scholarly journals Intrathoracic Axial Osteosarcoma

2018 ◽  
Vol 46 ◽  
pp. 6
Author(s):  
Paula Regina Silva Gomide ◽  
Cláudia Valéria Seullner Brandão ◽  
Vivian Rocco Babicsack ◽  
Bruno Watanabe Minto

Background: Bone tumors have a challenging diagnosis and treatment. Osteosarcoma is the name given to a heterogeneous group of malignant, agressive and invasive tumors that often determine bone lysis. Almost all of the animals develop lung metastases, progressing to death. Usually affect the appendicular skeleton, but can also occurs in others areas, although these presentations are rare. Prognosis is always poor. The aim of this paper is to report a case of a dog with osteoblastic osteosarcoma of the sternum, which was diagnosed by computed tomography and histopathologic analysis after excisional biopsy.Case: A male Cocker Spaniel dog, weighing 25 kg, elderly, was examined at the Veterinary Hospital. As main complaint was reported soft swelling on the ventral cervical region causing dyspnea. The patient had previously been medicated with dexamethasone with a significant decrease in the swelling, however recurrence was observed with the cessation of the treatment. Due to the presence of heart murmur, patient underwent to chest radiography and eletrocardiography. Images showed a tumor in the sternal lymph node region, displacing the heart caudally, trachea and esophagus dorsally, causing cranial edema due to a compression of the venous return by the cranial vena cava and subsequent dyspnea. Furosemide (Lasix®) was administered during ambulatorial treatment and prescribed to home, with satisfactory results, with decreased edema and consequent improvement of respiratory symptoms. It was decided to perform computed tomography to better design of the chest structure. The structure located in cranial thoracic region measured about 10.5 cm long x 5.8 cm high x 8.4 cm wide. The patient was undergone to sternotomy to remove the mass that was closely adhered to the sternum and pericardium. The pericardectomy and sternum removal were not performed due to animal being old and present metabolic and cardiopulmonary conditions. Some samples were collected for histological examination resulting in osteoblastic osteosarcoma. After surgical treatment, the patient showed improvement of dyspnea, more active and no signs of pain at the surgical site. Due to the unfavorable result of the histopathological analysis, it was decided to star chemotherapy. The protocol chosen was carboplatin (Carboplatino®) as a single drug, every 21 days totalizing four applications as recommended by literature. Two cycles of carboplatin were done as adjuvant chemotherapy. The patient supported the treatment very well without any clinical or laboratory abnormality. Any radiographic signs of pulmonary metastasis or local recurrence was seen, however, after 18 months of survival, the patient died of non-related cause.Discussion: Osteosarcoma is the most commonly diagnosed bone tumor in dogs. Intense dyspnea and the swelling in the submandibular region was due to the compression of thoracic structures by the size of the tumor and the internal location within the chest. The cranial swelling is due to the syndrome caval that is rare in veterinary medicine and is describe in some specific conditions. Computed tomography was performed to better tumor delineation, as it is an important tool to assess the extent of the tumor and other characteristics, allowing optimal surgical planning for each case. Histophatological diagnosis of osteoblastic osteosarcoma is characterized by new bone formation that appears radiographically with increased radiopacity, as observed in all images. Gold standard treatment of neoplasms is the association of surgical excision followed by chemotherapy, which was effective in this case reported, since it provided quality of life during 18 months, three times higher than the majority of cases reported in the literature, being death due to causes unrelated to the tumor.

2016 ◽  
Vol 19 (1) ◽  
pp. 028
Author(s):  
Shengjun Wu ◽  
Peng Teng ◽  
Yiming Ni ◽  
Renyuan Li

Coronary sinus aneurysm (CSA) is an extremely rare entity. Herein, we present an unusual case of an 18-year-old symptomatic female patient with a giant CSA. Secondary vena cava aneurysms were also manifested. The final diagnosis was confirmed by enhanced computed tomography (CT) and cardiac catheterization. As far as we know, it is the first case that such a giant CSA coexists with secondary vena cava aneurysms. Considering the complexity of postoperative reconstruction, we believe that heart transplantation may be the optimal way for treatment. The patient received anticoagulant due to the superior vena cava (SVC) thrombosis while waiting for a donor.


2020 ◽  
Vol 26 (1) ◽  
Author(s):  
Priyabrata Adhikari ◽  
Siddalingeshwar I. Neeli ◽  
Shyam Mohan

Abstract Background The presence of unilateral right-sided varicocele hints at a serious retroperitoneal disease such as renal cell neoplasm. Such tumors are usually associated with a thrombus in renal vein or spermatic vein. We report a rare presentation of right-sided renal tumor causing right-sided varicocele in the absence of thrombus in renal vein and spermatic vein but due to an anomalous vein draining from the tumor into the spermatic vein as demonstrated by computed tomography angiogram. Case presentation A 54-yr-old hypertensive male presented with unilateral grade 3 right-sided varicocele and no other signs and symptoms. Ultrasound examination of his abdomen showed the presence of a mass lesion in the lower pole of right kidney. Computed tomography confirmed the presence of right renal mass, absence of thrombus in right renal vein or inferior vena cava. The angiographic phase of CT scan showed an anomalous vein from the tumor draining into the pampiniform plexus causing varicocele. Conclusion The presence of right-sided varicocele should raise a suspicion hidden serious pathological retroperitoneal condition, renal malignancy in particular, and should prompt the treating physician to carry out imaging studies of the retroperitoneum and careful study of the angiographic phase of the CT scan can ascertain the pathogenesis of the varicocele.


2007 ◽  
Vol 43 (1) ◽  
pp. 45-51 ◽  
Author(s):  
Brian J. Trumpatori ◽  
Kyleigh Geissler ◽  
Kyle G. Mathews

Computed tomography was used to evaluate a 7-year-old English bulldog with a history of facial swelling and to aid in the diagnosis of parotid duct sialolithiasis. Removal of the sialolith with repair of the duct was not possible because of ductal fibrosis. Histological evaluation revealed glandular atrophy and fibrosis with lymphoplasmacytic inflammation. The parotid duct was ulcerated and fibrotic, with a mixed inflammatory infiltrate. Surgical excision of the parotid duct and salivary gland was curative.


2017 ◽  
Vol 65 (3) ◽  
pp. 260-264
Author(s):  
Isabella Lima Arrais RIBEIRO ◽  
Larissa Cavalcanti MONTEIRO ◽  
Ana Carolina Rodrigues de MELO ◽  
Tácio Candeia LYRA ◽  
Julio Cesar Campos FERREIRA FILHO ◽  
...  

ABSTRACT Introduction: Synovial sarcomas are rare and aggressive neoplasms located in the head and neck region and usually occurs in young adults. Presentation of case: This report presents a case of synovial sarcoma in a 15-year-old male patient who sought medical treatment for painful symptoms and associated dysphagia. The lesion was nodular, extensive, localized in the parotid region, and extended to the left cervical region. The patient was treated in a referral hospital with a treatment protocol that initially included chemotherapy for six months and surgery to attempt to excise the lesion, but the surgery was ineffective because removal could have damaged important vital structures. The Computed Tomography scan showed a hypodense area with diffuse growth and no involvement of the facial bones and the histopathological analysis revealed pleomorphic and oval spindle cells with rounded epithelial cells that formed nests surrounded by fibrous tissue. The Immunohistochemistry analysis was conclusive for the diagnosis of a high-grade SS in the parotid and left cervical regions. The medical team opted for palliative treatment with cervical radiotherapy. The patient remained hospitalized for four months after the surgery and died after 15 months since the diagnosis for compromise of airway by fast tumor growth. Conclusion: The synovial sarcoma, when diagnosed late may reduce the survival of patients because of the complications that tumor growth can bring to the prognosis and quality of life.


1992 ◽  
Vol 14 (3) ◽  
pp. 265-269 ◽  
Author(s):  
Ph Bonnichon ◽  
F Gaudard ◽  
B Lecam ◽  
J Shilder ◽  
D Pariente ◽  
...  

2014 ◽  
Vol 2014 ◽  
pp. 1-4
Author(s):  
Wataru Noguchi ◽  
Yoshihiro Inoue ◽  
Mana Fukushima

Here, we report a case of prostatic abscess probably due to malignant lymphoma of the prostate. An 82-year-old man was referred to our hospital with chief complaints of urinary frequency and discomfort on urination. Antibiotics were prescribed, but the symptoms remained and intermittent fever appeared. The patient was diagnosed with prostatic abscess by computed tomography (CT). Digital rectal examination (DRE) revealed soft prostate, and thick pus was milked out from the extrameatus by prostatic massage. For drainage, we performed transurethral resection of the prostate (TURP). Drainage by TURP was successful as CT clearly showed reduction of prostatic abscess after the operation. Nevertheless, intermittent fever did not improve and the patient’s general condition deteriorated. The day before the patient died, histopathological analysis showed prostatic abscess probably due to malignant lymphoma of the prostate and incidental adenocarcinoma. This is the first report of prostatic abscess with malignant lymphoma involving the prostate.


2019 ◽  
Vol 73 (1) ◽  
pp. 50-56
Author(s):  
Branislav Kureljusic ◽  
Slobodan Maksimovic ◽  
Slobodan Vujinovic ◽  
Bozidar Savic ◽  
Vesna Milicevic ◽  
...  

In this paper the case of a 2.5-year-old Simmental cow, with suspicion of lumpy skin disease in mid-2017 in Serbia will be presented. Clinical examination revealed numerous nodules of varied size from a few millimeters to approximately 10 centimeters disseminated predominantly on the skin of the udder and the perineum, some of which were coalescing and exulcerated. The general condition of the affected animal was unchanged. According to the results of laboratory analysis, the cow was negative for the presence of antibodies against the bovine leukemia virus, showed a negative reaction in tuberculinization and was vaccinated against lumpy skin disease virus. After the surgical excision of one skin node, the sample tested negative for the genome of lumpy skin disease virus. In order to establish the morphology of the skin lesion, a histopathological analysis was performed. Histopathological analysis showed the infiltration of the corium and subcutaneous tissue by numerous mononuclear cells showing cellular atypia. Suspicion of cutaneous lymphoma was established. Furthermore, the immunohistochemical examination confirmed that the infiltrate contained exclusively CD3-immunopositive cells, suggesting a T-cell origin nonepitheliotropic lymphoma.


2022 ◽  
pp. 519-521
Author(s):  
Mohd Monis ◽  
Divyashree Koppal ◽  
Aiman Ibbrahim ◽  
Zeeshan Nahid

Gastrointestinal liposarcomas are extremely rare with the most common reported morphological subtype being dedifferentiated liposarcoma and well-differentiated liposarcoma. These tumors are rarely diagnosed preoperatively and diagnosis is only confirmed on histopathological analysis. Treatment of gastrointestinal liposarcomas consists of surgical excision with widely negative margins followed by post-operative irradiation and close follow-up. We report an exceedingly rare case of myxoid liposarcoma of the small bowel (ileum) presenting with an unusual presentation with intussusception and intestinal obstruction. A 42-year-old male presented to the emergency department with features of intestinal obstruction. Contrast-enhanced computed tomography abdomen revealed ileo-ileal intussusception with an endoluminal soft-tissue lesion at the leading edge. The patient was taken for surgical intervention and the involved segment of the bowel along with the lesion was resected and re-anastomosis done. Histological sections of the mass along with immunohistochemistry suggested the pathological diagnosis of myxoid liposarcoma.


Sign in / Sign up

Export Citation Format

Share Document