An Approach to Acute, Subacute, Subchronic, and Chronic Toxicity Assessment in Animal Models

2015 ◽  
Vol 22 (2) ◽  
pp. 83
Author(s):  
Enegide Chinedu ◽  
David Arome ◽  
Fidelis Solomon Ameh ◽  
Dabum Luka Jacob
Keyword(s):  
Animal Models ◽  
Chronic Toxicity ◽  
Toxicity Assessment

scholarly journals Oral acute and sub-chronic toxicity assessment of aqueous leaf extract of Simarouba glauca DC (Paradise tree)

2021 ◽  
Vol 8 ◽  
pp. 239-247
Author(s):  
SD. E. Osagie-Eweka ◽  
N.E.J. Orhue ◽  
E.K.I. Omogbai ◽  
F.C. Amaechina
Keyword(s):  
Leaf Extract ◽  
Chronic Toxicity ◽  
Toxicity Assessment ◽  
Aqueous Leaf Extract ◽  
Simarouba Glauca

Acute and chronic toxicity assessment and the gene expression of Dhb, Vtg, Arnt, CYP4, and CYP314 in Daphnia magna exposed to pharmaceuticals

2015 ◽  
Vol 11 (2) ◽  
pp. 153-160 ◽  
Author(s):  
Seung Hyuck Bang ◽  
Ji-Young Ahn ◽  
Nam-Hui Hong ◽  
Simranjeet Singh Sekhon ◽  
Yang-Hoon Kim ◽  
...  
Keyword(s):  
Gene Expression ◽  
Daphnia Magna ◽  
Chronic Toxicity ◽  
Toxicity Assessment ◽  
Acute And Chronic Toxicity

scholarly journals Acute and chronic toxicity assessment of benzylpenicillin G residue in heat-treated animal food products

Chemosphere ◽  
2018 ◽  
Vol 202 ◽  
pp. 757-767 ◽  
Author(s):  
Cheng Cui ◽  
Xiang Zhang ◽  
Yang Wang ◽  
Shiying Lu ◽  
Huijun Lu ◽  
...  
Keyword(s):  
Chronic Toxicity ◽  
Food Products ◽  
Toxicity Assessment ◽  
Treated Animal ◽  
Animal Food ◽  
Acute And Chronic Toxicity ◽  
Heat Treated ◽  
Animal Food Products

A comparison of mixture toxicity assessment: Examining the chronic toxicity of atrazine, permethrin and chlorothalonil in mixtures to Ceriodaphnia cf. dubia

Chemosphere ◽  
2011 ◽  
Vol 85 (10) ◽  
pp. 1568-1573 ◽  
Author(s):  
Y.L. Phyu ◽  
C.G. Palmer ◽  
M.St.J. Warne ◽  
G.C. Hose ◽  
J.C. Chapman ◽  
...  
Keyword(s):  
Chronic Toxicity ◽  
Mixture Toxicity ◽  
Toxicity Assessment

Use of reverse osmosis as a polish for the cationic surfactant after electro-oxidative treatment: Acute and chronic toxicity assessment

2018 ◽  
Vol 163 ◽  
pp. 521-527
Author(s):  
Mariana S. Paula ◽  
Rodrigo P.M. Ribeiro ◽  
Alexandre A. Cerqueira ◽  
Fábio Merçon ◽  
Daniele Maia Bila ◽  
...  
Keyword(s):  
Reverse Osmosis ◽  
Cationic Surfactant ◽  
Chronic Toxicity ◽  
Toxicity Assessment ◽  
Oxidative Treatment ◽  
Acute And Chronic Toxicity

scholarly journals The Study in Animal Models of Local Action, Acute and Chronic Toxicity of Inactivated Influenza Vaccine Ultriks in Syringe

2015 ◽  
Vol 14 (3) ◽  
pp. 66-73 ◽  
Author(s):  
O. G. Kurskaya ◽  
K. A. Sharshov ◽  
A. Yu. Alekseev ◽  
M. A. Gulyaeva ◽  
A. M. Shestopalov ◽  
...  
Keyword(s):  
Animal Models ◽  
Influenza Vaccine ◽  
Intraperitoneal Injection ◽  
Intramuscular Injection ◽  
Chronic Toxicity ◽  
Local Effect ◽  
Experimental Animals ◽  
Single Intraperitoneal Injection ◽  
Acute And Chronic Toxicity ◽  
Single Intramuscular Injection

The evaluation of acute and chronic toxicity and local effect of the inactivated influenza vaccine Ultriks in animal models (guinea pigs, mice BALB/c) was performed. No vaccine-related toxic effect after a single intraperitoneal injection, multiple intramuscular injections, and no local irritant effect after a single intramuscular injection were reported in experimental animals.

Chronic Toxicity Assessment of 2′-O-Methoxyethyl Antisense Oligonucleotides in Mice

2018 ◽  
Vol 28 (4) ◽  
pp. 233-241 ◽  
Author(s):  
Thomas A. Zanardi ◽  
Tae-Won Kim ◽  
Lijiang Shen ◽  
David Serota ◽  
Chris Papagiannis ◽  
...  
Keyword(s):  
Antisense Oligonucleotides ◽  
Chronic Toxicity ◽  
Toxicity Assessment

Comparison of Brachionus calyciflorus 2-d and microtox® chronic 22-h tests with Daphnia magna 21-d test for the chronic toxicity assessment of chemicals

1999 ◽  
Vol 18 (10) ◽  
pp. 2178-2185 ◽  
Author(s):  
Pascal Radix ◽  
Marc Léonard ◽  
Christos Papantoniou ◽  
Gilles Roman ◽  
Erwan Saouter ◽  
...  
Keyword(s):  
Daphnia Magna ◽  
Chronic Toxicity ◽  
Toxicity Assessment ◽  
Brachionus Calyciflorus

scholarly journals Viability of the marine amphipod Parhyale hawaiensis growth rate as an endpoint for chronic ecotoxicological tests

2019 ◽  
Author(s):  
Patricia Kushima Assano ◽  
Gisela de Aragao Umbuzeiro ◽  
Otávio Jürgensen Diehl ◽  
Rhaul de Oliveira
Keyword(s):  
Growth Rate ◽  
Chronic Toxicity ◽  
Sediment Quality ◽  
Marine Species ◽  
Toxicity Assessment ◽  
Model Organisms ◽  
Toxicity Tests ◽  
Ecotoxicological Tests ◽  
Parhyale Hawaiensis ◽  
Marine Amphipod

There is a lack of suitable marine species for ecotoxicological tests. Parhyale hawaiensis is a marine amphipod with circumtropical distribution. Recently, acute ecotoxicological procedures were standardized for these model organisms. However, its potential for chronic toxicity assessment still unclear. Sediment quality assessments using sublethal responses of benthic organisms, such as growth and reproduction, have been used to successfully evaluate moderately contaminated areas. The aim of this work was to evaluate the viability of growth rate as an sublethal endpoint for chronic toxicity tests.

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