scholarly journals COMPARİSON OF PREOPERATİVE PENİLE ELASTOGRAPHİC ULTRASOUND FİNDİNGS AND PATHOLOGİCAL TİSSUE RESULTS OF PATİENTS İMPLEMENTED WİTH PENİLE PROSTHESİS

Author(s):  
Yunus Erol BOZKURT ◽  
Bilal Gumus ◽  
Fatih DÜZGÜN ◽  
Nalan NEŞE

Objective Histopathologically to determine the relationship between penile elastography ultrasonography and erectile dysfunction. Material and Method 12 patients who applied to our clinic for erectile dysfunction in the last 1 year and accepted this study were included . Preoperative two-dimensional shear wave elastography imaging was performed in 12 patients and recorded in the Pascal (kPa) unit. Approximately 0.5x0.5x0.5 cm tissue samples were taken from the right and left spongy tissue during penile prosthesis implantation operation. Tissue samples were sent to the pathology department. The percentage of the area covered by muscle fibers and elastic fibers in the corpus cavernosum was noted semi-quantitatively (ratio of muscle fibers and cavernous body elastic fiber score). All data obtained were compared with each other. Results Cavernous body elastic fiber score data(Grouped Score 1, 2 and 3) and percentage of cavernous body muscle fibers data (Grouped %10,%20,%30… %100) were compared with Shear wave elastography data (kPa). The results were not statistically significant according to the Kruskal Wallis Test and Spearman’s correlation test. Cavernous body elastic fiber score and the percentage of cavernous body muscle fibers were also compared, it was not statistically significant according to the Kruskal Wallis test and Spearman’s correlation test. The data we obtained as a result of our study showed that penile elastographic imaging is not a reliable method in the diagnosis of erectile dysfunction. Conclusions Penile shear wave elastography can be used clinically to quantitatively assess the amount of smooth muscle cells and elastic fibers in the penis, but it deserves to be studied with a larger number of patients and a more specific interpretation of the pathology preparation. Keywords: Penile elastography, erectile dysfunction, penile prosthesis, shear wave

2007 ◽  
Vol 33 (6) ◽  
pp. 785-794 ◽  
Author(s):  
Fabrizio Iacono ◽  
Domenico Prezioso ◽  
Stefania Chierchia ◽  
Raffaele Galasso ◽  
Gennaro Iapicca ◽  
...  

Ultrasound ◽  
2017 ◽  
Vol 25 (3) ◽  
pp. 150-155 ◽  
Author(s):  
Rustu Turkay ◽  
Ercan Inci ◽  
Mustafa Gurkan Yenice ◽  
Volkan Tugcu

Introduction Erectile dysfunction (ED) is a common health problem among males, and radiology has limited use in its diagnosis and treatment. Shear wave elastography (SWE) is a new sonographic technique. In this study, we examined the significance of SWE in the diagnosis of ED. Methods The study included a total number of 70 participants. The mean age of the participants was 54.14 ± 8.03 years (range: 39 and 71 years old). We composed two groups. Group 1 had 35 patients who presented to the urology clinic in our hospital complaining of ED, and had a score of 17 or lower from the International Index of Erectile Function (IIEF) questionnaire. Group 2 consisted of 35 healthy volunteers who did not have ED. SWE measurements were performed from corpus cavernosum penis in both groups, and the results were noted. Differences between the groups were evaluated statistically. Results The difference between the mean SWE measurements of two groups (Group 1: 20.94 ± 6.23 kPa and group 2: 24.63 ± 7.58 kPa) was found to be statistically significant ( p = 0.027; p < 0.05). For a cut-off value of 17.1 kPa, the SWE method has specificity, sensitivity, positive predictive value, and negative predictive value regarding diagnosis of ED as 94.29%, 34.29%, 85.71%, and 58.93%, respectively. The mean age of the groups did not show a statistically significant difference ( p = 0.287; p > 0.05). Conclusions Due to its high specificity and positive predictive value, SWE can offer useful data in the radiologic evaluation of ED cases.


Open Medicine ◽  
2010 ◽  
Vol 5 (2) ◽  
pp. 227-234 ◽  
Author(s):  
Özlem Baran ◽  
Mehmet Tuncer ◽  
Yusuf Nergiz ◽  
Murat Akkuş ◽  
Mahmut Erdemoğlu ◽  
...  

AbstractThis study has goals of examining whether pre-eclampsia may lead to an increase of elastic tissue fibers in blood vessel walls of placental stem villi or whether there are differences in the thickness of blood vessel walls within these villi when compared to normotensive pregnant women. Non-infarcted placental tissue samples from 28 participants with uncomplicated pregnancies and 26 patients with pre-eclampsia were obtained. After routine histological procedures, the sections were processed either for conventional Verhoeff staining for the demonstration of elastic fiber system. Paraffine sections from placenta biopsies prepared for light microscopic examination were gathered. In uncomplicated pregnancies, terminal villi blood vessels were observed with no stained elastic tissue fibers in most areas. In the pre-eclampsia pregnancy of human placenta, the elastic fibers significiantly increased in terminal villi blood vessel walls which were dark in color, using Verhoeff’s tissue stain, when comparing with the uncomplicated pregnancy group. Our results indicate that an increase of elastic tissue fibers in blood vessels of placental stem villus and terminal villi, and also an increase of wall thickness during pre-eclampsia.


Author(s):  
Wang Zhou ◽  
Yuyang Zhang ◽  
Liang Li ◽  
Jingjing Gao ◽  
Hui Zheng ◽  
...  

Author(s):  
Eugen Divjak ◽  
Gordana Ivanac ◽  
Niko Radović ◽  
Iva Biondić Špoljar ◽  
Slavica Sović ◽  
...  

Abstract Purpose To investigate if second-look US using shear-wave elastography (SWE) can help to differentiate between benign and malignant changes in the postoperative breast after surgical treatment of breast carcinoma. Materials and Methods SWE and related sonographic features were reviewed in 90 female patients with a history of surgical treatment of breast carcinoma and a suspicious lesion detected on a follow-up MRI scan. A single experienced radiologist performed all second-look US exams with SWE measurements placing a circular region of interest measuring 2 mm in diameter over the stiffest part of the lesion. Tissue samples for histopathological analysis were obtained during the same US examination via core-needle biopsy. Results Out of 90 lesions, 39 were proven malignant on histopathological analysis. 50 % of malignant lesions had Elmax values ranging from 128 to 199 kPa, and 50 % of benign lesions had Elmax values ranging from 65 to 169 kPa. The cut-off value of 171.2 kPa for Elmax shows a sensitivity of 59 % and specificity of 78.4 % for carcinoma recurrence, area under the curve 0.706 (CI95 % 0.6–0.81), P = 0.001. In univariate logistic models, restricted diffusion and stiffness on SWE, Elmax > 171.2 kPa, were shown as significant recurrence predictors. In the multivariate model, restricted diffusion remains significant independent recurrence predictor. With a recurrence prevalence of 43 %, the test sensitivity is 95 % (CI95 % 81–99 %) and the specificity is 75 % (CI95 % 60–85 %). Conclusion Stiffer lesions should be considered suspicious on second-look US in the postoperative breast and SWE can be a helpful tool in identifying malignant lesions, especially if this is related to restricted diffusion on MRI exam. Lesion stiffness, however, should not be considered as an independent predictor of lesion malignancy in the postoperative breast, because of benign changes that can appear stiff on SWE, as well as carcinoma recurrences that may appear soft.


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