scholarly journals The modified transmanubrial approach in thyroid malignant tumors: an optimal and less invasive surgical option.

2021 ◽  
Author(s):  
Paolo Nicola Girotti ◽  
Judit Gassner ◽  
Vebi Hodja ◽  
Ingmar Königsrainer
Keyword(s):  
Malignant Tumors ◽  
Thyroid Tumor ◽  
Middle Line ◽  
Thoracic Inlet ◽  
Thyroid Mass ◽  
Transmanubrial Approach ◽  
Vein Resection ◽  
Upper Thoracic ◽  
Cava Vein ◽  
Surgical Option

- We retrospectively evaluated a large series of patients (n: 15) underwent a modified transmanubrial approach for wide mediastinal resection in case of malignance thyroid mass - In fourteen cases, also with thyroid tumor involving the middle line. A bilateral mTMA was necessary to perform a cava vein resection. - No major postoperative and cutaneous/sternum complications were detected. - mTMA allows an optimal exposure of the upper thoracic inlet achieving a complete radical oncological resection of the tumor/lymph-node and a safety vascular/tracheal control. - As a limitation, the modified mTMA is anatomically more demanding and not familiar for most surgeons in comparison to sternotomy

Phyllodes Tumor Metastatic to Thyroid HürthleCell Adenoma

2002 ◽  
Vol 126 (10) ◽  
pp. 1233-1236
Author(s):  
Tamar Giorgadze ◽  
Richard M. Ward ◽  
Zubair W. Baloch ◽  
Virginia A. LiVolsi
Keyword(s):  
Tumor Metastasis ◽  
Unusual Case ◽  
Cellular Proliferation ◽  
Phyllodes Tumor ◽  
Thyroid Tumor ◽  
Cell Adenoma ◽  
Malignant Phyllodes Tumor ◽  
Hürthle Cell ◽  
Thyroid Mass ◽  
Tumor To Tumor Metastasis

Abstract We present a case of a malignant phyllodes tumor metastasizing to a Hürthle cell adenoma of the thyroid. A 55-year-old woman underwent mastectomy for a malignant phyllodes tumor. Two years later, she presented with a left thyroid mass, which was a single, circumscribed, soft, deep red-brown nodular lesion with an eccentric area of firmer consistency. Histologically, the thyroid tumor was composed of 2 distinct types of cellular proliferation. Atypical spindle cells were infiltrating between the Hürthle cell cords and follicles in a fibrosarcomatous pattern. A battery of immunohistochemical stains was applied to both the thyroid and breast tumors for comparison. Based on the histologic and immunophenotypic features of the fibrosarcomatous components of both the breast and thyroid tumors, we rendered a diagnosis of cystosarcoma phyllodes metastatic to Hürthle cell adenoma. To the best of our knowledge, this unusual case is a first report of tumor-to-tumor metastasis of a sarcoma to a primary thyroid neoplasm.

scholarly journals Intracardiac Metastasis from a Large Cell Neuroendocrine Lung Carcinoma

2019 ◽  
Vol 08 (01) ◽  
pp. e41-e43
Author(s):  
Christopher Gaisendrees ◽  
Kaveh Eghbalzadeh ◽  
Navid Mader ◽  
Thorsten C. W. Wahlers
Keyword(s):  
Lung Carcinoma ◽  
Malignant Tumors ◽  
Close Contact ◽  
Large Cell ◽  
Cardiac Metastasis ◽  
Cardiac Tumors ◽  
Cardiac Metastases ◽  
The Right ◽  
Cava Vein ◽  
Inferior Cava Vein

AbstractPrimary malignant tumors of the heart are rare; the biggest group is sarcomas. Cardiac metastases make up the biggest group of secondary cardiac tumors. We present a rare case of cardiac metastasis (3.1 × 3.2 × 2.8 cm) localized in the right atrium, originating from a large cell neuroendocrine lung carcinoma, with close contact to the tricuspid valve and inferior cava vein.

Technical Aspects of the Anterior Transmanubrial Approach in Thoracic Inlet Tumor Surgery

2012 ◽  
Vol 48 (11) ◽  
pp. 419-422 ◽  
Author(s):  
Antonio Francisco Honguero Martínez ◽  
Carlos A. Rombolá ◽  
Pablo León Atance
Keyword(s):  
Tumor Surgery ◽  
Thoracic Inlet ◽  
Technical Aspects ◽  
Transmanubrial Approach ◽  
Thoracic Inlet Tumor

scholarly journals Recurrent bilateral deep vein thrombosis after cava vein resection in a patient with leiomyosarcoma

2019 ◽  
Vol 54 (1) ◽  
pp. 1-1
Author(s):  
Lucia Ordieres-Ortega ◽  
Pablo Demelo-Rodríguez ◽  
Sandra Piqueras-Ruiz ◽  
Jorge del-Toro-Cervera
Keyword(s):  
Deep Vein Thrombosis ◽  
Vein Thrombosis ◽  
Vein Resection ◽  
Deep Vein ◽  
Cava Vein

Overcoming the transclavicular approach: The transmanubrial approach to the thoracic inlet

Head & Neck ◽  
2000 ◽  
Vol 22 (6) ◽  
pp. 629-630 ◽  
Author(s):  
Lorenzo Spaggiari ◽  
Luca Calabrese ◽  
Fausto Chiesa ◽  
Ugo Pastorino
Keyword(s):  
Thoracic Inlet ◽  
Transmanubrial Approach

scholarly journals RETROSPECTIVE ANALYSIS OF THE COURSE OF THYROID CARCINOMA WITH LUNG METASTASES AFTER RADIOIODINE THERAPY

2020 ◽  
Vol 17 (35) ◽  
pp. 728-738
Author(s):  
Olha M. ASTAPIEVA ◽  
Ganna V. GRUSHKA ◽  
Olga I. PASKEVYCH ◽  
Yuliia Ya. FEDULENKOVA ◽  
Oleksii V. MAKSIMISHYN
Keyword(s):  
Thyroid Carcinoma ◽  
Disease Progression ◽  
Radioiodine Therapy ◽  
Clinical Laboratory ◽  
Malignant Tumors ◽  
Lung Metastases ◽  
Survival Rates ◽  
Differentiated Thyroid Carcinoma ◽  
Thyroid Tumor ◽  
Medical Radiology

Metastasis of malignant tumors are one of the most acute problems of oncology. Among the organs and systems of the human body in terms of frequency of damage, one of the first places is occupied by the lungs, which is probably closely related to the anatomical features of their structure and physiology. During the first examination of cancer patients, metastases in the lungs are revealed in 6-15%, lymphogenous metastases are observed in 50-81%. With differentiated thyroid carcinoma (thyroid gland), metastases in the lung are most often detected (up to 15% of cases). At the same time, 5- and 10-year survival rates are 50-92.6% and 42-86%, respectively. The use of 131I-sodium iodide is central to the treatment of these patients. The purpose of the paper is to study the effectiveness of radioiodine therapy for metastases of thyroid carcinoma in the lung. We used clinical, laboratory, radiological methods for the diagnosis of thyroid carcinoma and pulmonary metastases. From 1986 to 2010, 68 patients from the clinic of the S.P. Hryhoriev Institute of Medical Radiology of the Academy of Medical Sciences of Ukraine were included in the study. Lung metastases were found in patients with all stages of the disease and with diverse sizes of the primary thyroid tumor. After the surgical treatment of patients, 131Isodium iodide was used in various doses of radioactivity. The full therapeutic effect of radiotherapy was achieved in 5 patients (7.8%) over a 3-year period of treatment, and a 5-year period – in 28 (43.8%); stabilization or partial effect was noted in 24 patients (37.8%), disease progression was observed in 12 patients (17.6%). Mortality from disease progression was 12.5%.

Lateral parascapular extrapleural approach to the upper thoracic spine

1991 ◽  
Vol 75 (3) ◽  
pp. 349-355 ◽  
Author(s):  
Richard G. Fessler ◽  
Donald D. Dietze ◽  
Michael Mac Millan ◽  
David Peace
Keyword(s):  
Nerve Root ◽  
Wound Dehiscence ◽  
Thoracic Vertebrae ◽  
Spinal Fixation ◽  
Thoracic Inlet ◽  
Content Type ◽  
Upper Thoracic ◽  
Extrapleural Approach ◽  
Fine Print ◽  
Shoulder Musculature

✓ The upper thoracic vertebrae are difficult to approach surgically because of the narrowing of the thoracic inlet, the proximity of the brachial plexus, and the parascapular shoulder musculature. A novel lateral parascapular extrapleural approach to the upper thoracic vertebrae is described. The parascapular shoulder musculature (trapezius, levator scapulae, and rhomboid muscles) is reflected off the spinous processes to the scapula as a musculocutaneous flap, preserving the neurovascular supply. The paraspinal musculature is mobilized and retracted, and the upper dorsal ribs are removed with caution to avoid injury to the C-8 and T-1 nerve roots. The rami communicantes are transected, and the sympathetic chain is displaced anterolaterally. The T2–4 vertebrae can be approached unobstructed. The T-1 nerve root obstructs posterolateral access to the T-1 vertebra, necessitating an inferolateral approach underneath the T-1 nerve root axilla. Four patients with compressive myelopathy from upper thoracic vertebral metastases underwent neural decompression, vertebral reconstruction, and posterior spinal fixation with this approach. Their postoperative neurological status was either unchanged or improved. Complications included radiographic pleural effusion and superficial wound dehiscence; one patient required posterior spinal reinstrumentation for progressive kyphosis. One patient developed pneumonia 7 days postoperatively which was unresponsive to appropriate treatment. It is believed that the anatomical limitations to this region have been overcome, and that excellent exposure of the T1–4 vertebrae for neural decompression and vertebral reconstruction can be performed safely. A major advantage is that posterior spinal fixation can be carried out simultaneously.

scholarly journals Transmanubrial approach to the thoracic inlet

1997 ◽  
Vol 113 (5) ◽  
pp. 958-959 ◽  
Author(s):  
Dominique Grunenwald ◽  
Lorenzo Spaggiari ◽  
Philippe Girard ◽  
Pierre Baldeyrou
Keyword(s):  
Thoracic Inlet ◽  
Transmanubrial Approach

scholarly journals Comparative analysis of the prevalence of the glutathione S-transferase (GST) system in malignant and benign thyroid tumor cells

2007 ◽  
Vol 125 (5) ◽  
pp. 289-291 ◽  
Author(s):  
Antonio José Gonçalves ◽  
Lucia Helena de Carvalho ◽  
Kauê Serdeira ◽  
Marianne Yumi Nakai ◽  
Tatiana Ramos Malavasi
Keyword(s):  
Head And Neck ◽  
Malignant Tumors ◽  
Thyroid Tissue ◽  
Neck Surgery ◽  
Thyroid Tumor ◽  
Double Negative ◽  
Glutathione S Transferase ◽  
Cross Sectional ◽  
De Medicina ◽  
Benign Thyroid

CONTEXT AND OBJECTIVE: When null, the mu and theta genes of the glutathione S-transferase system (GSTM1 and GSTT1, respectively) are related to malignant tumors affecting the lungs, colon, prostate, bladder and head and neck. In the thyroid, the appearance of cancer has been correlated with deletion of these genes. The aim of this study was to compare the frequencies of these genes in patients with benign and malignant tumors of the thyroid gland. DESIGN AND SETTINGS: This was a cross-sectional clinical trial carried out in the Head and Neck Surgery Division, Faculdade de Medicina da Santa Casa de São Paulo. METHODS: Samples of thyroid tissue were collected from 32 patients and divided into two groups: benign tumor (A) and malignant tumor (B). After DNA extraction, the genes were amplified using PCR. RESULTS: The B group presented four cases of positive genotyping for both genes, seven positive for GSTT1 and negative for GSTM1, two negative for GSTT1 and positive for GSTM1, and only one case of double negative. The A group showed 11 cases with positive genotyping for both genes and none with the double negative genotype. CONCLUSION: In this study, there was no relationship between the presence of the GSTT1 and GSTM1 genes and the benign and malignant thyroid tumors.

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