scholarly journals Food allergy in early childhood increases the risk of pollen-food allergy syndrome

2022 ◽  
Author(s):  
Kun Baek Song ◽  
Min Jee Park ◽  
Eom Ji Choi ◽  
Sungsu Jung ◽  
Ji-Sun Yoon ◽  
...  
Keyword(s):  
Early Childhood ◽  
Food Allergy ◽  
Birth Cohort ◽  
Age At Onset ◽  
Allergic Diseases ◽  
Population Based ◽  
Food Allergens ◽  
History Of ◽  
Skin Prick Tests ◽  
Inhalant Allergens

Abstract Background: The level of pollen in Korea has increased over recent decades. Research suggests that pollen-food allergy syndrome (PFAS) may be more frequent in childhood than previously recognized. We aimed to investigate the prevalence and characteristics of PFAS in children aged 6–10 years from a general population-based birth cohort. Methods: We analyzed 930 children from the COhort for Childhood Origin of Asthma and allergic diseases (COCOA) birth cohort. Allergic diseases were diagnosed annually by pediatric allergists. The skin prick tests were performed with 14 common inhalant allergens and four food allergens for children aged 3 and 7 years. Results: Of the 930 eligible children, 44 (4.7%) aged 6–10 years were diagnosed with. The mean age at onset was 6.74 years. PFAS prevalence was 7.2% among children with allergic rhinitis (AR) and 19.1% among those with pollinosis, depending on comorbidity. PFAS was more prevalent in schoolchildren with atopic dermatitis, food allergy, and sensitization to food allergens and grass pollen in early childhood. In schoolchildren with AR, only a history of food allergy before 3 years increased the risk of PFAS (aOR 2.971, 95% CI: 1.159–7.615). Conclusion: Food allergy and food sensitization in early childhood was associated with PFAS in schoolchildren with AR. Further study is required to elucidate the mechanism by which food allergy in early childhood affects the development of PFAS.

scholarly journals The prevalence of food allergy and other allergic diseases in early childhood in a population-based study: HealthNuts age 4-year follow-up

2017 ◽  
Vol 140 (1) ◽  
pp. 145-153.e8 ◽  
Author(s):  
Rachel L. Peters ◽  
Jennifer J. Koplin ◽  
Lyle C. Gurrin ◽  
Shyamali C. Dharmage ◽  
Melissa Wake ◽  
...  
Keyword(s):  
Early Childhood ◽  
Food Allergy ◽  
Allergic Diseases ◽  
Population Based ◽  
Population Based Study

Prenatal and early-life predictors of atopy and allergic disease in Canadian children: results of the Family Atherosclerosis Monitoring In earLY life (FAMILY) Study

2016 ◽  
Vol 7 (6) ◽  
pp. 665-671 ◽  
Author(s):  
T. Batool ◽  
P. L. Reece ◽  
K. M. Schulze ◽  
K. M. Morrison ◽  
S. A. Atkinson ◽  
...  
Keyword(s):  
Food Allergy ◽  
Birth Cohort ◽  
Allergic Disease ◽  
Early Life ◽  
Skin Prick Testing ◽  
Allergic Diseases ◽  
Population Based ◽  
Life Study ◽  
The Family ◽  
Study Population

Prenatal and early-life environmental exposures play a key role in the development of atopy and allergic disease. The Family Atherosclerosis Monitoring In earLY life Study is a general, population-based Canadian birth cohort that prospectively evaluated prenatal and early-life traits and their association with atopy and/or allergic disease. The study population included 901 babies, 857 mothers and 530 fathers. Prenatal and postnatal risk factors were evaluated through questionnaires collected during the antenatal period and at 1 year. The end points of atopy and allergic diseases in infants were evaluated through questionnaires and skin prick testing. Key outcomes included atopy (24.5%), food allergy (17.5%), cow’s milk allergy (4.8%), wheezing (18.6%) and eczema (16%). The association between infant antibiotic exposure [odds ratio (OR): 2.04, 95% confidence interval (CI): 1.45–2.88] and increased atopy was noted in the multivariate analysis, whereas prenatal maternal exposure to dogs (OR: 0.60, 95% CI: 0.42–0.84) and acetaminophen (OR: 0.68, 95% CI: 0.51–0.92) was associated with decreased atopy. This population-based birth cohort in Canada demonstrated high rates of atopy, food allergy, wheezing and eczema. Several previously reported and some novel prenatal and postnatal exposures were associated with atopy and allergic diseases at 1 year of age.

Staphylococcus aureus sensitization and allergic disease in early childhood: Population-based birth cohort study

2007 ◽  
Vol 119 (4) ◽  
pp. 930-936 ◽  
Author(s):  
Aida Semic-Jusufagic ◽  
Claus Bachert ◽  
Philippe Gevaert ◽  
Gabriele Holtappels ◽  
Lesley Lowe ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Early Childhood ◽  
Cohort Study ◽  
Birth Cohort ◽  
Allergic Disease ◽  
Population Based ◽  
Birth Cohort Study ◽  
Childhood Population

scholarly journals Hypersensitivity and the Working Environment for Allergy Nurses in Sweden

2014 ◽  
Vol 2014 ◽  
pp. 1-7
Author(s):  
Pia Kalm-Stephens ◽  
Therese Sterner ◽  
Kerstin Kronholm Diab ◽  
Greta Smedje
Keyword(s):  
Allergic Diseases ◽  
Working Environment ◽  
National Guidelines ◽  
Allergen Specific Immunotherapy ◽  
Exhaust Ventilation ◽  
Provocation Tests ◽  
History Of ◽  
Challenge Tests ◽  
Skin Prick Tests ◽  
Personnel Safety

Background. Allergy nurses are exposed to allergens and respiratory irritants, and there are no national guidelines addressing personnel safety when working with these agents. Objective. To investigate the prevalence of allergies, asthma, and hypersensitivity symptoms among allergy nurses and the use of protective equipment and measures when working with allergen concentrates and respiratory irritants. Methods. A questionnaire survey was performed among the members of the Swedish Association of Allergy Nurses. Results. Diagnosed asthma was reported by 17%, while 18% had allergy to pets, 28% had allergy to pollens, and 26% reported nasal symptoms. Fifty-one percent reported a history of asthma, allergic diseases, or hypersensitivity symptoms in their family. Exhaust ventilation was used by 24% during skin prick tests, 17% during allergen specific immunotherapy, and 33% when performing methacholine challenge tests. Tightly closed containers for disposable waste were used by 58% during skin prick tests, by 60% during immunotherapy, and by 40% during Pc provocation tests. Conclusion. Allergy nurses had a tendency to increased prevalence of lower respiratory symptoms, asthma, and allergic rhinitis and more than half of the nurses had a family history of asthma, allergic diseases, or hypersensitivity symptoms. Additional studies are needed to evaluate the validity of these results.

scholarly journals A Web-based Survey for the Association Between Food Allergy and Depression/psychological Distress in 11,876 Japanese (P18-019-19)

2019 ◽  
Vol 3 (Supplement_1) ◽  
Author(s):  
Shinsuke Hidese ◽  
Shun Nogawa ◽  
Kenji Saito ◽  
Hiroshi Kunugi
Keyword(s):  
Food Allergy ◽  
Psychological Distress ◽  
Control Group ◽  
Food Allergens ◽  
Kiwi Fruit ◽  
Web Based ◽  
Funding Sources ◽  
Depression Group ◽  
Japanese Sample ◽  
History Of

Abstract Objectives The aim of this study is to examine whether food allergy (FA) is associated with depression/psychological distress in a large Japanese sample. Methods This web-based survey was conducted on a platform of “Yahoo! JAPAN -HealthData Lab” and the Genequest Inc. (Tokyo, Japan). Participants were 1000 individuals with self-reported history of depression (mean age: 41.4 years, 501 men and 499 women) and the remaining 10,876 controls (mean age: 45.1 years, 5691 men and 5185 women). Six-item Kessler scale (K6) test cut-off score ≥13 was used to estimate severe psychological distress. We gained self-reported information on FA and 27 specific food allergens. Results The proportion of individuals with FA, 2 or more, 3 or more, and 4 or more allergens was higher in the depression group compared to the control group (odds ratio [OR] = 1.64, 1.75, 2.02, and 2.27, respectively; P < 0.001). Allergen analyses revealed that allergies for shrimp, egg, mackerel, crab, kiwi fruit, milk, banana, and squid were more common in the depression group compared to the control group (P < 0.05). Individuals who had severe psychological distress was more common in the FA group than in the non-FA group, in the total participants (OR = 1.32, 1.62, 2.04 and 2.51; 1, 2, 3, and 4 or more allergens, respectively; P < 0.001). Conclusions We suggest that FA is likely to be a risk factor for depression and severe psychological distress, which is dependent on the number of food allergens. Funding Sources This work was supported by an Intramural Research Grant for Neurological and Psychiatric Disorders of National Center of Neurology and Psychiatry.

scholarly journals The Impact of Family History of Allergy on Risk of Food Allergy: A Population-Based Study of Infants

2013 ◽  
Vol 10 (11) ◽  
pp. 5364-5377 ◽  
Author(s):  
Jennifer Koplin ◽  
Katrina Allen ◽  
Lyle Gurrin ◽  
Rachel Peters ◽  
Adrian Lowe ◽  
...  
Keyword(s):  
Food Allergy ◽  
Family History ◽  
Population Based ◽  
Population Based Study ◽  
History Of ◽  
The Impact

Schizotypal and affective traits in the offspring of antenatally depressed mothers – Relationship to family history of psychosis in the Northern Finland 1966 Birth Cohort

2017 ◽  
Vol 42 ◽  
pp. 36-43 ◽  
Author(s):  
T. Taka-Eilola (née Riekki) ◽  
J. Miettunen ◽  
P. Mäki
Keyword(s):  
General Population ◽  
Birth Cohort ◽  
Depressed Mood ◽  
Familial Risk ◽  
Population Based ◽  
Adult Offspring ◽  
Parental History ◽  
Affective Traits ◽  
History Of ◽  
Depressed Mothers

AbstractBackgroundMaternal depression is relatively common during pregnancy. However, follow-ups of the adult offspring of antenatally depressed mothers are scarce. Previously we found the risk of schizophrenia to be higher in the adult offspring with antenatally depressed mothers and parents with psychosis than in subjects with only one or neither of these risk factors. The aim was to study whether the risk of schizotypal or affective traits differ among adult offspring with antenatally depressed mothers with or without a parental history of psychosis when compared with offspring without antenatally depressed mothers and without parental psychosis.MethodsIn the general population-based Northern Finland 1966 Birth Cohort (NFBC 1966), the mothers of the cohort members were asked at mid-gestation whether they felt depressed. Parental psychosis (Familial Risk, FR) was detected using the Finnish Care Register for Health Care. In the 31-year field study, seven psychometric questionnaires surveyed schizotypal and affective traits in the offspring. The final sample included 4928 individuals (2203 males).ResultsThere were no statistically significant differences in mean scores on the schizotypal and affective scales between offspring with and without antenatally depressed mothers, or between subjects with and without parental psychosis. The scores were not highest in the subjects with both maternal antenatal depressed mood and FR.ConclusionSurprisingly, maternal depressed mood during pregnancy was unlikely to increase the risk of schizotypy or affective traits in adult offspring, and not even with parental psychosis (FR) in this general population-based birth cohort with about 5000 subjects.

scholarly journals Prediction of peanut allergy in adolescence by early childhood storage protein-specific IgE signatures: The BAMSE population-based birth cohort

2017 ◽  
Vol 140 (2) ◽  
pp. 587-590.e7 ◽  
Author(s):  
Anna Asarnoj ◽  
Carl Hamsten ◽  
Christian Lupinek ◽  
Erik Melén ◽  
Niklas Andersson ◽  
...  
Keyword(s):  
Early Childhood ◽  
Birth Cohort ◽  
Storage Protein ◽  
Peanut Allergy ◽  
Specific Ige ◽  
Population Based

Parental mental illness and fatal birth defects in a national birth cohort

2007 ◽  
Vol 38 (10) ◽  
pp. 1495-1503 ◽  
Author(s):  
R. T. Webb ◽  
A. R. Pickles ◽  
S. A. King-Hele ◽  
L. Appleby ◽  
P. B. Mortensen ◽  
...  
Keyword(s):  
Mental Illness ◽  
Birth Cohort ◽  
Birth Defects ◽  
Birth Defect ◽  
Population Based ◽  
Parental Mental Illness ◽  
Risk Of Death ◽  
Maternal Illness ◽  
Relative Risks ◽  
History Of

BackgroundFew large studies describe links between maternal mental illness and risk of major birth defect in offspring. Evidence is sparser still for how effects vary between maternal diagnoses and no previous study has assessed risk with paternal illnesses.MethodA population-based birth cohort was created by linking Danish national registers. We identified all singleton live births during 1973–1998 (n=1.45 m), all parental psychiatric admissions from 1969 onwards, and all fatal birth defects until 1 January 1999. Linkage and case ascertainment were almost complete. Relative risks were estimated using Poisson regression.ResultsRisk of fatal birth defect was elevated in relation to history of any maternal admission and also with affective disorders specifically, although the strongest effect found was with maternal schizophrenia. The rate was more than doubled in this group compared to the general population [relative risk (RR) 2.34, 95% confidence interval (CI) 1.45–3.77], which also represented a significant excess risk compared with all other admitted maternal disorders (p=0.018). Risk of death from causes other than birth defect was no higher with schizophrenia than with other maternal conditions. There was no elevation in risk of fatal birth defect if the father was admitted with schizophrenia or any other psychiatric diagnosis.ConclusionsThere are many possible explanations for a higher risk of fatal birth defect with maternal schizophrenia and affective disorder. These include genetic effects directly linked with maternal illness, lifestyle factors (diet, smoking, alcohol and drugs), poor antenatal care, psychotropic medication toxicity, and gene–environment interactions. Further research is needed to elucidate the causal mechanisms.

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