scholarly journals Montmorillonite K-10 supported one-pot synthesis of some symmetric diimides and 3a,4,7,7a-tetrahydroisoindole-1,3-dione derivatives under solvent-free conditions using microwaves

2005 ◽  
Vol 70 (4) ◽  
pp. 579-583 ◽  
Author(s):  
Davood Habibi ◽  
Omid Marvi
Keyword(s):  
Nmr Spectroscopy ◽  
Maleic Anhydride ◽  
Microwave Irradiation ◽  
Elemental Analysis ◽  
1H Nmr Spectroscopy ◽  
Solvent Free ◽  
One Pot ◽  
Solvent Free Conditions ◽  
High Yields ◽  
Aromatic And Aliphatic Amines

The syntheses of cis-3a,4,7,7a-tetrahydroisoindole-1,3-dione derivatives and some cyclic diimides were performed by the reaction of different aromatic and aliphatic amines and diamines with cis-1,2,3,6-tetrahydrophthalic anhydride and maleic anhydride on montmorillonite K-10 under microwave irradiation and solvent- free conditions. The desired attractive products were obtained in high yields and characterized by elemental analysis aswell as by IR and 1H-NMR spectroscopy.

A One-Pot, Three-Component, Solvent-Free Synthesis of Novel 6H-Chromeno[3’,4’:5,6]Pyrido[2,3-d]Pyrimidine-Triones under Microwave Irradiation

2018 ◽  
Vol 42 (12) ◽  
pp. 604-607
Author(s):  
Loghman Firoozpour ◽  
Hoda Yahyavi ◽  
Ramona Ejtemaei ◽  
Setareh Moghimi ◽  
Alireza Foroumadi
Keyword(s):  
Microwave Irradiation ◽  
Efficient Method ◽  
Barbituric Acid ◽  
Reaction Times ◽  
Solvent Free ◽  
One Pot ◽  
Solvent Free Conditions ◽  
Substituted Benzaldehydes ◽  
High Yields ◽  
Solvent Free Synthesis

A green and efficient method for preparing novel heterocyclic systems is established through the reaction of differently substituted benzaldehydes, barbituric acid and 4-amino-2H-chromene-2-one under solvent-free conditions. This method affords 6H-chromeno[3’,4’:5,6] pyrido[2,3-d]pyrimidine-trione derivatives in high yields and short reaction times.

1,3-Dibromo-5,5-dimethylhydantoin as a useful reagent for efficient synthesis of 3,4-dihydropyrimidin-2-(1H)-ones under solvent-free conditions

2009 ◽  
Vol 63 (1) ◽  
Author(s):  
Mohammad Abdollahi-Alibeik ◽  
Zahra Zaghaghi
Keyword(s):  
Microwave Irradiation ◽  
Ethyl Acetoacetate ◽  
Biginelli Reaction ◽  
Reaction Times ◽  
Solvent Free ◽  
Efficient Synthesis ◽  
One Pot ◽  
Aliphatic Aldehydes ◽  
Solvent Free Conditions ◽  
High Yields

AbstractEfficient syntheses of 3,4-dihydropyrimidin-2-(1H)-ones and the corresponding thioxo derivatives using 1,3-dibromo-5,5-dimethylhydantoin (DBH) catalysis of a one-pot three-component Biginelli reaction of aldehydes, ethyl acetoacetate, and urea or thiourea under microwave irradiation are described. The advantages of this method are its short reaction times, high yields of the products, inexpensive and commercially available catalyst, and solvent-free conditions. Typical isolated yields exceed 70 % for arylaldehydes (9 examples) and aliphatic aldehydes (2 examples).

An efficient, Green Synthesis of benzo[a]furo[2, 3-c]phenazine derivatives via Microwave-Assisted and TiO2-SO3H as Cost-effective and Recyclable Catalyst under solvent-free conditions

2020 ◽  
Vol 17 ◽  
Author(s):  
Milad Taheri ◽  
Razieh Mohebat ◽  
Mohammad Hossein Moslemin
Keyword(s):  
Microwave Irradiation ◽  
Solid Acid Catalyst ◽  
Internal Standard ◽  
Acid Catalyst ◽  
Cost Effective ◽  
Solvent Free ◽  
One Pot ◽  
Solvent Free Conditions ◽  
High Yields ◽  
Recyclable Heterogeneous Catalyst

Background: A rapid, efficient, and environmentally benign procedure for the synthesis of novel furo [2,3- c]phenazine derivatives has been developed via reactions of 2-hydroxynaphthalene-1,4-dione, arylglyoxals, and indole in the presence of TiO2-SO3H-catalyst (TSAC) as a recyclable heterogeneous catalyst under solvent-free conditions using microwave irradiation. Introduction: This study describes a successful approach for the synthesis of 2-(4-bromophenyl)-1-(1H-indol-3-yl) benzo[a]furo[2,3-c] phenazine via TiO2-SO3H-catalyst using microwave irradiation. Objectives: In this paper, we wish to report an efficient and convenient method for the synthesis of phenazine derivatives from benzo[a]phenazin-5-ol, arylglyoxal derivatives, and Indoles in the presence of TiO2-SO3H-catalyst under microwave irradiation. Materials and Methods: All reagents and solvent were purchased from Merck and Aldrich and used without further purification. 1H NMR spectra (DMSO) were recorded on Gemini-500 MHz spectrophotometer with TMS as internal standard. Results and Discussions: To investigate the reaction conditions for the synthesis of 2-(4-bromophenyl)-1-(1H-indol-3-yl) benzo[a]furo [2, 3-c] phenazine derivatives, we performed a reaction between 2-hydroxynaphthalene-1,4-dione (1 mmol) and aromatic 1,2-diamines (1 mmol) as a model. Conclusion: We demonstrated a green and straightforward procedure for the efficient synthesis of novel benzo[a]furo[2, 3- c] phenazine derivatives in high yields via a one-pot, four-component domino protocol by using TiO2-SO3H as a mild, effective, non-toxic, and inexpensive solid acid catalyst without the addition of an organic co-solvent.

Facile one-pot synthesis of sugar–thiazolidinone derivatives

2011 ◽  
Vol 89 (11) ◽  
pp. 1382-1386 ◽  
Author(s):  
Ali Darehkordi ◽  
Kazem Saidi ◽  
Somayeh Ghazi
Keyword(s):  
Microwave Irradiation ◽  
Ambient Temperature ◽  
Cost Effective ◽  
Solvent Free ◽  
One Pot ◽  
One Pot Synthesis ◽  
Cost Effective Method ◽  
Solvent Free Conditions ◽  
High Yields

A simple, efficient, and cost-effective method for the synthesis of a series of sugar–thiazolidinone derivatives by a one-pot reaction of the corresponding thiosemicarbazone of d-galactose, d-glucose, and d-mannose compounds in the presence of dimethyl or diethyl acetylenedicarboxylate is described. Two different methods were used and high yields were obtained in both cases: (A) in EtOAC–H2O at an ambient temperature and (B) microwave irradiation under solvent-free conditions.

Uncatalysed Preparation of α-Amino Phosphonates under Solvent Free Conditions

2005 ◽  
Vol 2005 (5) ◽  
pp. 324-327 ◽  
Author(s):  
Mohamed Zahouily ◽  
Abdelhakim Elmakssoudi ◽  
Abdessamad Mezdar ◽  
Ahmed Rayadh ◽  
Saïd Sebti
Keyword(s):  
Microwave Irradiation ◽  
Carbonyl Compounds ◽  
Environmentally Friendly ◽  
Solvent Free ◽  
Aliphatic Amines ◽  
Solvent Free Conditions ◽  
Dialkyl Phosphites ◽  
High Yields ◽  
Amino Phosphonates ◽  
Aromatic And Aliphatic Amines

A simple, efficient and environmentally friendly procedure has been developed for the three component coupling of carbonyl compounds, aromatic and aliphatic amines and dialkyl phosphites to produce α-amino phosphonates. The α-amino phosphonates are synthesised in high yields (74–97%) in a few minutes (1–3 min) by microwave irradiation under solvent-free conditions, avoiding the use of any catalyst.

A highly efficient and green approach for the synthesis of pyrimido[4,5-b]quinolines using N,N-diethyl-N-sulfoethanaminium chloride

2021 ◽  
Vol 76 (2) ◽  
pp. 85-90
Author(s):  
Abdolkarim Zare ◽  
Manije Dianat
Keyword(s):  
Reaction Times ◽  
Solvent Free ◽  
One Pot ◽  
Catalyst Amount ◽  
Green Protocol ◽  
Highly Efficient ◽  
Green Approach ◽  
Solvent Free Conditions ◽  
The One ◽  
High Yields

Abstract A highly efficient and green protocol for the synthesis of pyrimido[4,5-b]quinolines has been described. The one-pot multicomponent reaction of dimedone with arylaldehydes and 6-amino-1,3-dimethyluracil in the presence of N,N-diethyl-N-sulfoethanaminium chloride ([Et3N–SO3H][Cl]) as an ionic liquid (IL) catalyst under solvent-free conditions afforded the mentioned compounds in high yields and short reaction times. Our protocol is superior to many of the reported protocols in terms of two or more of these factors: the reaction times, yields, conditions (solvent-free versus usage of organic solvents), temperature and catalyst amount.

scholarly journals Tandem Fries Reaction–Conjugate Addition under Microwave Irradiation in Dry Media; One-pot Synthesis of Flavanones

1999 ◽  
Vol 23 (9) ◽  
pp. 574-575
Author(s):  
Firouz Matloubi Moghaddam ◽  
Mohammad Ghaffarzadeh ◽  
Seyed Hossein Abdi-Oskoui
Keyword(s):  
Microwave Irradiation ◽  
Silica Gel ◽  
Conjugate Addition ◽  
Solvent Free ◽  
Naphthalene Derivatives ◽  
One Pot ◽  
Fries Rearrangement ◽  
One Pot Synthesis ◽  
Solvent Free Conditions ◽  
Fries Reaction

An AICl3–ZnCl2 mixture supported on silica gel is found to be an efficient medium for the Fries rearrangement of acyloxybenzene or naphthalene derivatives in solvent-free conditions under microwave irradiation.

Rapid and Green One-Pot Synthesis of Novel 2-(4-Hydroxy-2-oxo-2H-chromen-3-yl)-2-(arylamino)-1H-indene-1,3(2H)-diones

2021 ◽  
Vol 18 ◽  
Author(s):  
Abolfazl Olyaei ◽  
Zahra Ghahremany ◽  
Madieh Sadeghpour
Keyword(s):  
Aromatic Amines ◽  
Low Cost ◽  
Guanidine Hydrochloride ◽  
Reaction Times ◽  
Solvent Free ◽  
One Pot ◽  
Solvent Free Conditions ◽  
The One ◽  
High Yields ◽  
Work Up

: A green and efficient protocol was developed for the one-pot three-component synthesis of novel 2-(4-hydroxy-2-oxo-2H-chromen-3-yl)-2-(arylamino)-1H-indene-1,3(2H)-dione derivatives by the reaction of 4-hydroxycoumarin, ninhydrin and aromatic amines in the presence of guanidine hydrochloride as an organocatalyst under solvent-free conditions. The present approach offers several advantages such as low cost, simple work-up, short reaction times, chromatography-free purification, high yields and greener conditions.

TiO2–SiO2 nanocomposite as a highly efficient catalyst for the solvent-free cyclocondensation reaction of isatins, cyclohexanones, and urea

2019 ◽  
Vol 74 (7-8) ◽  
pp. 559-564
Author(s):  
Simin Janitabar-Darzi ◽  
Shahrzad Abdolmohammadi
Keyword(s):  
Present Method ◽  
High Efficiency ◽  
Solvent Free ◽  
High Catalytic Activity ◽  
One Pot ◽  
Efficient Catalyst ◽  
Solvent Free Conditions ◽  
Cyclocondensation Reaction ◽  
The One ◽  
High Yields

AbstractA TiO2–SiO2 nanocomposite catalyzes the one-pot cyclocondensation reaction of 1H-indole-2,3-diones (isatins), 1,3-cyclohexanediones, and urea at T = 70°C under solvent-free conditions with high efficiency. The present method affords the corresponding spiro products in high yields and short reaction time. The unique features of the TiO2–SiO2 nanocomposite are high catalytic activity, ease of preparation, non-toxicity, low loading, and recyclability.

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