Some Statistical Considerations in the Selection of Research Projects in the Pharmaceutical Industry

Author(s):  
O. L. Davies
2016 ◽  
Vol 66 (2) ◽  
pp. 289-295
Author(s):  
Borche Stamatoski ◽  
Miroslava Ilievska ◽  
Hristina Babunovska ◽  
Nikola Sekulovski ◽  
Sasho Panov

AbstractMicrobiological control is of crucial importance in the pharmaceutical industry regarding the possible bacterial contamination of the environment, water, raw materials and finished products. Molecular identification of bacterial contaminants based on DNA sequencing of the hypervariable 16SrRNA gene has been introduced recently. The aim of this study is to investigate the suitability of gene sequencing using our selection of PCR primers and conditions for rapid and accurate bacterial identification in pharmaceutical industry quality control.DNA was extracted from overnight incubated colonies from 10 bacterial ATCC strains, which are common contaminants in the pharmaceutical industry. A region of bacterial 16SrRNA gene was analyzed by bidirectional DNA sequencing. Bacterial identification based on partial sequencing of the 16SrRNA gene is the appropriate method that could be used in the pharmaceutical industry after adequate validations. We have successfully identified all tested bacteria with more than 99 % similarity to the already published sequences.


Author(s):  
Bruce Calway

Education practices, like Work-Integrated Learning, result from a confluence of educational issues, and contextual and philosophical influences. This chapter commences with an overview of the Work-Integrated Learning philosophy, the contextual modifiers and the education issues that provide the framework for Work-Integrated Learning education practices. Issues in investigating or researching Work-Integrated Learning and research paradigm possibilities are explored. It is contended that adoption of a holistic research paradigm for future Work-Integrated Learning research projects is needed to avoid simplistic assessments of Work-Integrated Learning that fail to advance experiential learning (e.g. Dewey, 1938) in school-to-work and workforce scenarios, in any meaningful way. Selection of the neo-positivist research paradigm is argued.


2011 ◽  
Vol 30 (01) ◽  
pp. 65-70
Author(s):  
Amy L. Fletcher

Reviewing the work of Lynton Caldwell, Robert Blank, and Andrea Bonnicksen is both a privilege and a challenge. These three scholars rank among the key figures in the development of biopolicy as a legitimate research and teaching subfield within political science. Each of them worked in academia, on significant bioethical advisory boards, and with policymaking entities, and also contributed to numerous externally funded research projects. Across long and prolific careers, Caldwell, Blank, and Bonnicksen engaged seriously with the political, social and ethical issues raised by significant advances in many bio-scientific domains. This essay analyzes several of their works across two broad themes: 1) the development of the subfields of biopolitics and biopolicy, and 2) the tension between science policy and democratic governance. While each of them wrote significant and well-received books, the focus here is on insights to be gleaned from an idiosyncratic selection of their scholarly articles across the time period, 1966 to 2007. To borrow Michel Foucault's term, this brief and necessarily selective archaeology of the published journal record nevertheless demonstrates the significance, durability and prescience of the authors' insights. (I expect that at least one, if not all three, of these authors might raise objections to the mention of Foucault, but the term “archaeology” in this instance is apt.)


2020 ◽  
Vol 19 (3) ◽  
pp. ar31
Author(s):  
Michelle A. Maher ◽  
Annie M. Wofford ◽  
Josipa Roksa ◽  
David F. Feldon

This study explored how biological science doctoral students made decisions about fitting with a principal investigator (PI) and within a research lab. Results illuminated a complex array of factors students considered in selecting a PI, including PI mentoring style and professional stability. Peers and research projects played an important role in students’ lab selection.


2007 ◽  
Vol 9 (7) ◽  
pp. 785 ◽  
Author(s):  
J. Dewulf ◽  
G. Van der Vorst ◽  
W. Aelterman ◽  
B. De Witte ◽  
H. Vanbaelen ◽  
...  

1969 ◽  
Vol EM-16 (1) ◽  
pp. 2-8 ◽  
Author(s):  
Anthony C. Atkinson ◽  
Arthur H. Bobis

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