The Liver and Portal System

2017 ◽  
Author(s):  
Jared A White

Understanding of the anatomy and physiology of the liver and techniques for safe anatomic and nonanatomic liver resections has evolved over the past several decades. The liver is composed of a complex arterial and portal venous inflow, which has several important variants that are crucial for the surgeon to understand when planning hepatic resections, both anatomic and nonanatomic. In addition, intra- and extrahepatic biliary configurations may be encountered, and variants must be recognized to prevent complications during common surgical procedures, such as cholecystectomy and liver resection. The liver is responsible for numerous metabolic, homeostatic, and immunologic processes throughout the body. It is crucial for the practicing physician and surgeon to have a fundamental understanding of hepatic anatomy and physiology when treating patients with derangements in liver structure and function.  Key words: bile duct, bilirubin, bilirubin metabolism, hepatic artery, hepatic blood flow, hepatic parenchyma microstructure, liver anatomy, portal hypertension, portal vein

2017 ◽  
Author(s):  
Jared A White

Understanding of the anatomy and physiology of the liver and techniques for safe anatomic and nonanatomic liver resections has evolved over the past several decades. The liver is composed of a complex arterial and portal venous inflow, which has several important variants that are crucial for the surgeon to understand when planning hepatic resections, both anatomic and nonanatomic. In addition, intra- and extrahepatic biliary configurations may be encountered, and variants must be recognized to prevent complications during common surgical procedures, such as cholecystectomy and liver resection. The liver is responsible for numerous metabolic, homeostatic, and immunologic processes throughout the body. It is crucial for the practicing physician and surgeon to have a fundamental understanding of hepatic anatomy and physiology when treating patients with derangements in liver structure and function.  Key words: bile duct, bilirubin, bilirubin metabolism, hepatic artery, hepatic blood flow, hepatic parenchyma microstructure, liver anatomy, portal hypertension, portal vein


Author(s):  
Walter Bonani ◽  
Claudio Migliaresi ◽  
Wei Tan

Essential to growing or regenerating 3-dimensional tissues is the formation of functional microcirculation that provides nutrients, oxygen and signal molecules for tissue survival and function regeneration. In the past decade, molecule-based microvascular formation has been achieved in vitro and in vivo. However, direct delivery of angiogenic molecules often results in malformed hyperpermeable microvessels, microvessels with low density. This can be attributed to the lack of effective molecule mechanisms that regulate vascular formation. More recent studies utilize biodegradable materials to control the delivery of biomolecules for vascularization of engineered or ischemic tissues, and exciting results have shown the importance of molecule kinetics to the vascular formation. Molecule delivery mechanisms that mimic precisely-regulated spatiotemporal signaling events during natural vascularization may be a possible way to improve or optimize the process. Hence, this study is designed to develop a new release system capable of degrading in the body and releasing biomolecules in a spatiotemporally controlled manner.


2012 ◽  
Vol 4 (3) ◽  
pp. 378
Author(s):  
Raodah Raodah

AbstrakPenelitian mengkaji arsitektur tradisional Makassar rumah adat Balla Lompoa, bekas istana Raja Gowa. Rumah adat itu berlokasi di Kota Sungguminasa, Kabupaten Gowa, Sulawesi Selatan. Arsitektur rumah adat Balla Lompoa berbentuk rumah pang-gung, mencerminkan bentuk kebudayaan masa lampau. Tujuan penelitian, mengung-kapkan bentuk dan fungsi ruang, struktur bangunan, ragam hias, kosmologi dalam arsitektur Balla Lompoa. Metode penelitian yang digunakan bersifat deskriptif dengan pendekatan kualitatif. Teknik pengumpulan data berupa wawancara, pengamatan, dan studi pustaka. Hasil penelitian menunjukkan bentuk dan fungsi bangunan  Balla Lompoa  terdiri dari tiga bagian, yaitu bagian atas disebut loteng atau pammakang, bagian tengah merupakan badan rumah disebut kale balla, dan bagian bawah atau kolong yang disebut passiringan. Arsitekturnya menganut falsafah sulapa appa yang menggambarkan segala aspek kehidupan manusia barulah sempurna jika berbentuk segi empat. Falsafah tersebut direfleksikan pada areal tanah, tiang rumah, jendela dan ruangan.  AbstractThis paper is a result of my research on traditional architecture of adat house Balla Lompoa, former palace of the King of Gowa. It is located in the city of Sungguminasa, Residence of Gowa, South Sulawesi. Balla Lompoa is a rumah panggung (house on stilts) that reflects cultural forms of the past. The aim of the study is to reveal form and function of the rooms, building structure, ornaments, and cosmology in the architecture. This is a descriptive research with qualitative approach. Data was compiled through observation, interviews, and bibliographic study. The result finds that the form and function of Balla Lampoa consist of three parts: upper part is called loteng or pammakang, middle part, which is the body of the house, called kale balla; and the lower part called passiringan. The house conveys philosophical value called sulappa appa, describing that perfect life of a human being is in the form of square. It is applied to the land are, house posts, windows, and rooms.


2020 ◽  
Author(s):  
Junior Kimwah ◽  
Ismail Ibrahim ◽  
Hj Baharudin Mohd Arus

Artikel ini membincangkan artifak boat-shaped coffin atau keranda berbentuk perahu yang terdapat di dalam Gua Kain Hitam (Painted Cave) Niah, Sarawak. Artifak berbentuk perahu ini dipercayai digunakan sebagai keranda pada suatu ketika dahulu. Keranda ini dipercayai dihasilkan oleh masyarakat neolitik yang menghuni sekitar Gua Kain Hitam pada ketika itu. Upacara kematian yang diamalkan ini bersifat primary burial. Mayat disimpan di dalam keranda perahu sehingga reput sepenuhnya. Kemudian, baki tulang tersebut ditanam di tapak pengebumian lain yang terletak di Gua Kain Hitam II. Penyelidikan ini menekankan kaedah pemerhatian secara langsung di lapangan. Subjek penyelidikan difoto dan direkodkan secara terperinci melalui fotografi dan buku lakaran. Hasil penyelidikan ini menjelaskan reka bentuk dan fungsi serta kegunaan boat-shaped coffin pada suatu ketika dahulu. Hasil analisis kandungan terhadap hubung kait keranda dan lukisan gua prasejarah yang ditemui menunjukkan ruangan Gua Kain Hitam berfungsi sebagai death chamber. Justeru, penyelidikan ini dapat mendokumentasi dan memelihara artifak secara kolektif untuk tatapan masyarakat akan datang.   This article discusses on boat-shaped coffin artefacts found in the Painted Cave of Niah, Sarawak. This boat-shaped artefact is believed have been used as a caoffin in the past. The coffin is believed have been maded by the neolithic people who lived around the Painted Cave at that time. This ritual of death is a primary burial. The body was stored in the boat’s coffin until it was completely decomposed. The remains were then buried at another burial site, located in the Painted Cave II. This research emphasizes the method of direct observation in the field. The research subjects were photographed and recorded in detail through photography and sketches. The results of this research explain the design and function and use of boat-shaped coffins in the past. The results of the analysis from the contents of the coffin linkages and prehistoric cave drawings found that the Painted Cave spaces served as a death chamber. As such, this research can document and conserve artefacts collectively for the public to see.


Author(s):  
Martin E. Atkinson

Human anatomy concerns the structure of the human body. Anatomy is often interpreted as the study of only those structures that can be seen with the naked eye (gross anatomy). Anatomy also covers the study of structure at the cellular (histology) and subcellular level (ultrastructure). The formation (embryology) and growth of anatomical structures (developmental anatomy) influence their organization, appearance, and their relationship to other structures and often explain gross anatomical arrangement. Historically, physiology (the study of the function of the body) was regarded as a separate subject from anatomy but the relationships between structure and function (functional anatomy) is critical to understanding how the body works at all levels. Most modern dental curricula now have some degree of integration between anatomy and physiology to emphasize their interrelationship in the study of the human body. It is impossible to recognize changes in structure brought about by disease and their clinical manifestations and effects on function without an understanding of healthy structure and function. It is impossible to use any surgical procedures effectively and safely without a good working knowledge of the anatomy of the relevant part of the body. In clinical work, internal structures often need to be located accurately even when they cannot be visualized directly. A good example of this is the need to be able to locate the nerves supplying the teeth in order to deliver local anaesthetic accurately prior to carrying out a restoration or extraction. Fortunately, most structures have a fairly constant relationship to surface features (surface anatomy) to allow their position to be determined with considerable accuracy. Information about deep structures can also be obtained by the use of imaging techniques such as X-rays or scanning technology. Interpretation of radiographs and scans requires knowledge of the radiographic appearance of normal body structures (radiological anatomy). Surface and radiological anatomy are obviously of great practical importance and are covered in the relevant sections of the book. The principal aim of this book is to provide you with sufficient practical information about the anatomy of the human body to form a basis on which to build your clinical skills and practice.


Author(s):  
Azadeh Zarei ◽  
Samaneh Noroozi ◽  
Ebrahim Khadem

Persian medicine (PM) scholars have explained the structure and function of each organ based on clinical observations and past experiences. The liver is one of the three commanders in the body (brain, heart, liver) that manages nutrition and growth. This study was aimed to evaluate the anatomy and physiology of the Liver as presented in PM school and compare with conventional medicine. Relevant keywords were searched through PM reference books, Google scholar, PubMed, Web of Science and Scopus. After extracting the data, the results were classified in terms of concepts and categories. PM scholars believe that liver is one of the first organs created in the fetal period. In their view, the liver has a warm and wet temperament. In this manner the natural blood’s temperament is warm and wet and it arises from the temperance of the liver and its correct function. In conventional medicine, the Liver consists an operational unit called hepatic lobule and plays an important role in the metabolism of the nutrition’s and growth of tissues. Overview of fetal origin, structure and function of the liver between these two schools of medicine interpreted in many ways, revealed many similarities. Thus, we can utilize PM’s point of view on the liver and its important functions in the body, especially in the field of disease prevention and treatment.


Author(s):  
K.E. Krizan ◽  
J.E. Laffoon ◽  
M.J. Buckley

With increase use of tissue-integrated prostheses in recent years it is a goal to understand what is happening at the interface between haversion bone and bulk metal. This study uses electron microscopy (EM) techniques to establish parameters for osseointegration (structure and function between bone and nonload-carrying implants) in an animal model. In the past the interface has been evaluated extensively with light microscopy methods. Today researchers are using the EM for ultrastructural studies of the bone tissue and implant responses to an in vivo environment. Under general anesthesia nine adult mongrel dogs received three Brånemark (Nobelpharma) 3.75 × 7 mm titanium implants surgical placed in their left zygomatic arch. After a one year healing period the animals were injected with a routine bone marker (oxytetracycline), euthanized and perfused via aortic cannulation with 3% glutaraldehyde in 0.1M cacodylate buffer pH 7.2. Implants were retrieved en bloc, harvest radiographs made (Fig. 1), and routinely embedded in plastic. Tissue and implants were cut into 300 micron thick wafers, longitudinally to the implant with an Isomet saw and diamond wafering blade [Beuhler] until the center of the implant was reached.


Derrida Today ◽  
2013 ◽  
Vol 6 (1) ◽  
pp. 97-114 ◽  
Author(s):  
Christopher Morris

Over the past thirty years, academic debate over pornography in the discourses of feminism and cultural studies has foundered on questions of the performative and of the word's definition. In the polylogue of Droit de regards, pornography is defined as la mise en vente that is taking place in the act of exegesis in progress. (Wills's idiomatic English translation includes an ‘it’ that is absent in the French original). The definition in Droit de regards alludes to the word's etymology (writing by or about prostitutes) but leaves the referent of the ‘sale’ suspended. Pornography as la mise en vente boldly restates the necessary iterability of the sign and anticipates two of Derrida's late arguments: that there is no ‘the’ body and that performatives may be powerless. Deriving a definition of pornography from a truncated etymology exemplifies the prosthesis of origin and challenges other critical discourses to explain how pornography can be understood as anything more than ‘putting (it) up for sale’.


Somatechnics ◽  
2017 ◽  
Vol 7 (2) ◽  
pp. 288-303
Author(s):  
Michael Connors Jackman

This article investigates the ways in which the work of The Body Politic (TBP), the first major lesbian and gay newspaper in Canada, comes to be commemorated in queer publics and how it figures in the memories of those who were involved in producing the paper. In revisiting a critical point in the history of TBP from 1985 when controversy erupted over race and racism within the editorial collective, this discussion considers the role of memory in the reproduction of whiteness and in the rupture of standard narratives about the past. As the controversy continues to haunt contemporary queer activism in Canada, the productive work of memory must be considered an essential aspect of how, when and for what reasons the work of TBP comes to be commemorated. By revisiting the events of 1985 and by sifting through interviews with individuals who contributed to the work of TBP, this article complicates the narrative of TBP as a bluntly racist endeavour whilst questioning the white privilege and racially-charged demands that undergird its commemoration. The work of producing and preserving queer history is a vital means of challenging the intentional and strategic erasure of queer existence, but those who engage in such efforts must remain attentive to the unequal terrain of social relations within which remembering forms its objects.


Author(s):  
Raphael A. Cadenhead

Although the reception of the Eastern father Gregory of Nyssa has varied over the centuries, the past few decades have witnessed a profound awakening of interest in his thought, particularly in relation to the contentious issues of gender, sex, and sexuality. The Body and Desire sets out to retrieve the full range of Gregory’s thinking on the challenges of the ascetic life through a diachronic analysis of his oeuvre. Exploring his understanding of the importance of bodily and spiritual maturation in the practices of contemplation and virtue, Raphael Cadenhead recovers the vital relevance of this vision of transformation for contemporary ethical discourse.


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