scholarly journals Bone availability for mandibular molar distalization in adults with mandibular prognathism

2017 ◽  
Vol 88 (1) ◽  
pp. 52-57 ◽  
Author(s):  
Young Tak Choi ◽  
Yoon-Ji Kim ◽  
Kyung-Sook Yang ◽  
Dong-Yul Lee
Keyword(s):  
Mixed Models ◽  
Class I ◽  
Class Iii ◽  
Class Iii Malocclusion ◽  
Molar Distalization ◽  
Mandibular Prognathism ◽  
Second Molar ◽  
Mandibular Molar ◽  
Mandibular Second Molar ◽  
The Right

ABSTRACT Objectives: To investigate the retromolar space available for molar distalization in patients with mandibular prognathism. Materials and Methods: Using cone-beam computed tomography, the posterior mandibular dimensions in 110 consecutive patients with Class I or Class III malocclusion were measured (mean age, 27.0 ± 7.1 years). The shortest linear distances from the distal root of the right mandibular second molar to the inner border of the mandibular cortex were measured at the level of root furcation and 2, 4, and 6 mm apical to the furcation along the sagittal line and the posterior line of occlusion. The retromolar distances were compared between the Class I and Class III malocclusion groups using general linear mixed models. Results: The retromolar space measured through the sagittal line showed no significant intergroup difference. Among the distances measured through the posterior line of occlusion, the space measured at depths 0 and 2 mm to the furcation were significantly greater in the Class III group than in the Class I group. Conclusions: Patients with Class III malocclusion have greater retromolar space for mandibular molar distalization along the posterior line of occlusion only at the level of the second molar furcation.

scholarly journals Analysis Of MYO1H Single Nucleotide Polymorphism In Class III Malocclusion With Mandibular Prognathism: A Preliminary Study

2017 ◽  
Vol 16 (2) ◽  
Author(s):  
Siti Nazirah Yahya ◽  
Nurul Syafiqah Abdul Razak ◽  
Noraini Abu Bakar ◽  
Khairani Idah Mokhtar ◽  
Azrul Fazwan Kharuddin
Keyword(s):  
Single Nucleotide Polymorphism ◽  
Local Population ◽  
Class I ◽  
Class Iii ◽  
Class Iii Malocclusion ◽  
Nucleotide Polymorphism ◽  
Marker Allele ◽  
Single Nucleotide ◽  
Allele Distribution ◽  
Mandibular Prognathism

Introduction: Evidence suggests that several genes; including MYO1H, play an important role in the etiology of Class III malocclusion. Single nucleotide polymorphism (SNP) in marker rs10850110 (locus 12q24.11) within MYO1H gene has been associated with the incidence of mandibular prognathism (MP). MYO is a class 1 myosin that is responsible for the synthesis of Matrilin-1; an important protein involved in the formation of cartilage's extracellular matrix, hence is implicated in the formation of mandibular condyle cartilage. This study aimed to detect the presence of MYO1H (rs10850110) SNP and to determine its genotype and allele distribution in MP patient in the local population. Materials and Methods: The sample comprises of 31 patients; 14 patients from class I malocclusion (control samples) and 17 patients from class III malocclusion (MP). Cephalometric measurements were performed prior to saliva samples collection. The DNA was amplified using the specific primers for the marker rs10850110 and the genotyping was done by sequencing. Chi-square test was used to determine the over-representation of marker allele (p<0.05). Results:  Presence of MYO1H SNP (rs10850110) was detected in local population analysed and the distribution of its genotype and allele could be observed. There were significant differences between allele (p=0.000) and genotype (p=0.000) frequency within control (Class I) and Class III malocclusion. Conclusion(s):  Our findings are in agreement with previous studies suggesting positive influence of MYO1H (rs10850110) SNP in the incidence of MP. Further studies should be developed in order to understand the exact role and mechanism of MYO1H in different classes of malocclusions.

scholarly journals Identification Of PAX9 Single Nucleotide Polymorphism In Class III Malocclusion Patients With Mandibular Prognatism

2017 ◽  
Vol 16 (2) ◽  
Author(s):  
Noraini Abu Bakar ◽  
Khairani Idah Mokhtar ◽  
Azrul Fazwan Kharuddin
Keyword(s):  
Single Nucleotide Polymorphism ◽  
Local Population ◽  
Class I ◽  
Class Iii ◽  
Class Iii Malocclusion ◽  
Nucleotide Polymorphism ◽  
Chi Square ◽  
Marker Allele ◽  
Single Nucleotide ◽  
Mandibular Prognathism

Introduction: PAX9 (Paired box 9) gene is one of the genes which play significant role during craniofacial development. Single nucleotide polymorphism (SNP) in PAX9 has been associated with Class II/Division 2 malocclusion (with or without hypodontia). However, the relationship between PAX9 SNP marker (rs8004560) with mandibular prognathism (MP) has not been analysed, at least in our local population. This study aimed to detect the presence of PAX9 (rs8004560) SNP in Class III malocclusion patients (with MP) in the local population. Materials and Methods: Genomic DNA were extracted from unstimulated saliva of 31 class I malocclusion (control samples) and 30 patients from Class III malocclusion (MP). Cephalometric measurements were performed prior to saliva samples collection. The DNA was amplified using the specific primers for the marker rs8004560 and the genotyping was done by sequencing. Chi-square test was used to determine the overrepresentation of marker allele (p<0.05). Results:  Presence of PAX9 SNP (rs8004560) was detected in local population analysed and the distribution of its genotype and allele could be observed. There were significant differences between allele (p=0.000) and genotype (p=0.000) frequency within control (Class I) and Class III malocclusion. Conclusion(s): The most common allele of a marker flanking PAX9 (rs8004560) was over-represented in the mandibular prognathism (MP) subjects indicating the genetic association of PAX9 (rs8004560) SNP in the incidence of MP. Further studies involving larger number of samples should be developed in order to understand the exact role and mechanism of PAX9 in different classes of malocclusions.

scholarly journals Treatment of Class III Malocclusion in an Adolescent with Banded RPE/Face Mask and Self-Ligating System

2017 ◽  
Vol 1 ◽  
Author(s):  
Dwita Pratiwi Dwita Pratiwi ◽  
Benny Mulyono Soegiharto
Keyword(s):  
Orthodontic Treatment ◽  
Face Mask ◽  
Class I ◽  
Adolescent Patient ◽  
Class Iii ◽  
Class Iii Malocclusion ◽  
Facial Profile ◽  
The Right ◽  
Cervical Vertebral Maturation ◽  
Dental Malocclusion

<p>This case report describes the treatment of a 12-years-old female with a Class III skeletal profile and dental malocclusion. The clinical examination showed concave profile, class III dental relationship, buccal crossbite on the right side, and mild crowding. The cervical vertebral maturation analysis showed the patient was on the CS3 stage. The class III malocclusion was treated with combination of banded rapid palatal expander and face mask followed by non-extraction orthodontic treatment with self-ligating system. Banded rapid palatal expander and face mask were used to improve the skeletal discrepancy. Class I maxilla-mandibular relationship was achieved along with class I molar, incisor, and canine relationship. The buccal crossbite and mild crowding were corrected, the overbite and overjet were normal, and the facial profile was improved. This case demonstrates a good result of a class III malocclusion treatment in an adolescent patient with banded rapid palatal expander/face mask and self-ligating system.</p>

scholarly journals Analysis of MYO1H Gene Polymorphism in Skeletal Class-III Malocclusion Due to Mandibular Prognathism

2021 ◽  
Author(s):  
Anjana Atteeri ◽  
Praveen Kumar Neela ◽  
Pavan Kumar Mamillapalli ◽  
Vasu M. Sesham ◽  
Sreekanth Keesara ◽  
...  
Keyword(s):  
Local Population ◽  
Research Work ◽  
Control Group ◽  
Study Group ◽  
Genome Wide Association Studies ◽  
Class Iii ◽  
Class Iii Malocclusion ◽  
Mandibular Prognathism ◽  
Skeletal Class ◽  
Increased Risk

Abstract Background Mandibular prognathism (MP) is a craniofacial deformity resulting from the combined effects of environmental and genetic factors. Although various linkage and genome-wide association studies for mandibular prognathism have identified multiple strongly associated regions and genes, the causal genes and variants responsible for the deformity remained ambiguous. Aim This research work was aimed to study the association between polymorphism rs10850110 of the MYO1H gene and skeletal class-III malocclusion in our local population. Materials and Methods Thirty patients with skeletal class III due to mandibular prognathism in the study group and 30 patients with skeletal class I in the control group were selected for this study. These patients were from both sexes and above age 10 years. Based on the cephalometric values, patients were categorized into study and control groups. SNB (angle between sella, nasion and point B at nasion) greater than 82 degrees with an ANB (angle between point A, nasion and point B at nasion) of less than 0 degrees in the study group and ANB (angle between point A, nasion and point B at nasion) of 2 to 4 degrees in the control group were categorized. The polymorphism (rs10850110) of the MYO1H gene was genotyped using polymerase chain reaction and restriction fragment length polymorphism. Associations were tested with SNP exact test using SNPstats software. Results The single-nucleotide polymorphism rs10850110 showed a statistically significant association with mandibular prognathism. The G allele of marker rs10850110 (5′ of myosin1H - MYO1H) was overrepresented when compared with the “A” allele in mandibular prognathism cases (p < 0.0001), and this was very significant. Conclusion These results suggest that the rs10850110 polymorphism of the MYO1H gene is associated with an increased risk for mandibular prognathism.

scholarly journals The Short-Term Effect of Active Skeletonized Sutural Distractor Appliance on Temporomandibular Joint Morphology of Class III Malocclusion Subjects

2021 ◽  
Author(s):  
Mohamed Zahoor Ul Huqh ◽  
Rozita Hassan ◽  
Roselinda Abdul Rahman ◽  
Asilah Yusof ◽  
Ida Bagus Narmada ◽  
...  
Keyword(s):  
Temporomandibular Joint ◽  
Term Effect ◽  
Class Iii ◽  
Class Iii Malocclusion ◽  
Short Term ◽  
Short Term Effect ◽  
Condylar Position ◽  
Joint Morphology ◽  
The Right ◽  
Condylar Volume

Abstract Objectives The purpose of this study was to evaluate the short-term effect of active skeletonized sutural distractor (ASSD) appliance on temporomandibular joint morphology of class III malocclusion subjects. Materials and Methods This was a prospective interventional study. Cone-beam computerized tomography (CBCT) images of 22 patients were taken before and after treatment by using Planmeca Promax 3D CBCT machine version 2.9.2 (Planmeca OY Helsinki, Finland). The condylar width, height, length, roof of glenoid fossa thickness, and all joint spaces were measured. The condylar position was determined based on Pullinger and Hollander formula. The condylar shape was determined as per Kinzinger et al. The condylar volume was calculated by using Mimics software (Materialize, Belgium). Statistical Analysis Data analysis was performed by using SPSS software version 24. Wilcoxon paired signed-rank test was used to compare the difference in temporomandibular joint morphology and condylar volume between pre- and post-treatment measurements. Chi-square test was used to compare the condylar position and shape. Results The superior (p = 0.000 on the right side, p = 0.005 on the left side) and posterior joint spaces (p = 0.000 on both sides) were decreased after the treatment, respectively. The condyles were rotated upward and backward, thereby increasing the anterior joint spaces (p = 0.000 on both sides) after the treatment. The condylar volume increases after treatment, but no significant differences were observed (p = 0.903 on the right side, p = 0.062 on the left side). Conclusion The significant changes were observed in joint spaces. The condyles were more anteriorly placed before treatment. Condylar position and shape alter in response to ASSD treatment. The condylar volume did not show any significant change.

scholarly journals Correction of severe facial asymmetry: A case with fractured condyle

2019 ◽  
Vol 9 ◽  
pp. 59-64
Author(s):  
Ramesh Agrawal ◽  
Dolly P. Patel ◽  
Bhagyashree B. Desai
Keyword(s):  
Facial Asymmetry ◽  
Post Treatment ◽  
Radiographic Examination ◽  
Rigid Fixation ◽  
Class Iii ◽  
Class Iii Malocclusion ◽  
History Of ◽  
Condylar Head ◽  
The Stability ◽  
The Right

The current paper depicts the challenges faced during the treatment of a complicated case of mandibular condylar head fracture, facial asymmetry, and centric relation-centric occlusion (CR-CO) discrepancy along with Class III malocclusion. A 20-year-old female reported with the chief complaint of difficulty in chewing and concern with her appearance due to deviated jaw and had a history of trauma over chin region. The clinical and radiographic examination revealed significant facial asymmetry with long face, right-sided deviation of the mandible, fractured condyle, CR-CO discrepancy, cross- bite with Class III malocclusion, and a missing mandibular single incisor along with non-vital 21 and 22. She was treated with 0.022 MBT appliance along with guiding plane for CR-CO correction followed by asymmetric bilateral sagittal split osteotomy and differential set back on the right and left sides and finally rigid fixation. A good facial profile and functional occlusion were achieved and non-vital 21 and 22 were esthetically rehabilitated with PFM crowns. The stability of surgical as well as orthodontic corrections was excellent and appreciable in the records obtained 2-year post-treatment. When faced with mutilated malocclusion, with multiple problems, sequential correction of functional malocclusion with dental decompensation followed by skeletal correction with surgical approach has yielded a appreciable facial correction with good stability showing 2-year post-treatment follow-up.

scholarly journals Nonsurgical Treatment of Class III Malocclusion with Both Anterior and Posterior Crossbites Combined with Impacted and Congenitally Missed Teeth

2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Yahya A. Alogaibi ◽  
Ahmed R. Afify ◽  
Ahmad A. Al-Fraidi ◽  
Ali A. Hassan
Keyword(s):  
Composite Resin ◽  
Functional Results ◽  
Deciduous Teeth ◽  
Class Iii ◽  
Class Iii Malocclusion ◽  
Viable Option ◽  
Skeletal Class ◽  
Posterior Crossbite ◽  
The Right ◽  
Leveling And Alignment

Class III malocclusions present a great challenge for many orthodontists, especially if malocclusions are found in adult patients and alongside other dental problems. This case report shows an adult patient with a skeletal class III anterior crossbite, a unilateral posterior crossbite on the right side, a congenital absence of both lateral incisors and retained deciduous teeth, and shift in the lower midline. The upper retained deciduous teeth and lower premolars were extracted. Leveling and alignment were initiated. Build-up composite resin placed on the first molars allowed for bite opening. The crossbites were corrected by using sequentially larger archwires combined with class III elastics until both the anterior and posterior crossbites were corrected. The impacted upper right canine was exposed using the closed eruption technique and leveled into the position of the upper lateral incisor. Miniscrews were utilized to close the residual spaces. Both canines were reshaped to simulate the upper lateral incisors. At the end of the treatment, good esthetic and functional results were obtained. In conclusion, orthodontic camouflage can be a viable option for treating patients with multiple skeletal and dental problems.

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