scholarly journals Long-term Observation for Space Closing of Maxillary Incisors with Severe Alveolar Bone Loss by Fixed Minor Tooth Movement Appliance. A Case Report.

Author(s):  
Masafumi Shiraki ◽  
Tsuneo Ishihara ◽  
Hiroshi Iwanaga ◽  
Shingo Nagasawa ◽  
Yukio Iwayama
2019 ◽  
Vol 46 (8) ◽  
pp. 799-808 ◽  
Author(s):  
Paula Tegelberg ◽  
Tellervo Tervonen ◽  
Matti Knuuttila ◽  
Jari Jokelainen ◽  
Sirkka Keinänen‐Kiukaanniemi ◽  
...  

2013 ◽  
Vol 72 (4) ◽  
pp. 148-155 ◽  
Author(s):  
Chisa Shitano ◽  
Otto Baba ◽  
Sawa Kaneko ◽  
Jun Hosomichi ◽  
Yasuhiro Shimizu ◽  
...  

Author(s):  
Masahiro Asano ◽  
Yoji Asahara ◽  
Akinori Kirino ◽  
Mika Ohishi ◽  
Noriko Akimaru ◽  
...  

1990 ◽  
Vol 61 (7) ◽  
pp. 434-437 ◽  
Author(s):  
Cynthia A. Layport ◽  
George W. Greco ◽  
Walter T. McFall

2017 ◽  
Vol 20 (4) ◽  
pp. 42 ◽  
Author(s):  
Daniela Martins de Souza ◽  
Alan De Aquino Silva ◽  
Kauê Alberto Pereira ◽  
Vitor Sulz Gonsalves ◽  
Vinicius Anéas Rodrigues ◽  
...  

<p><strong>Objective:</strong> The aim of the present study was to assess the effect of regular and constant long-term alcohol consumption on the percentage of the remaining periodontal bone support (PBS) and periodontal bone loss (PBL) in adult rats. <strong>Material and Methods: </strong>Fifty-four (54) rats were divided into 3 groups: Control (daily water intake, n=18) daily alcohol intake (20% ethanol, n=18) and social alcohol intake (20% ethanol 2x a week, n=18). The rats were treated with continuous free-choice access to both ethanol consumption frequencies. They were euthanized after 90 days and their left mandibles were radiographed for PBS measuring. The same left mandibles were defleshed and stained. The PBL was morphometrically assessed by measuring the distance between cement-enamel junction and alveolar bone crest. <strong>Results: </strong>Did not show difference (p &gt; 0.05) in the amount of consumed alcohol between the social and daily intake groups. Rats also evidenced lower PBS percentage and higher PBL (p&lt;0.05) in both alcohol consumption groups in comparison to the control. <strong>Conclusion: </strong>The long-term constant and regular same amount alcohol consumption may cause alveolar bone loss and reduce the remaining periodontal bone support in adult rats. Thus, the alveolar bone loss was associated with the amount of consumed alcohol, rather than with periodicity in periodontitis-free rats.</p><p><strong>Keywords</strong></p><p>Alveolar Bone Loss; Alcoholism; Ethanol; Periodontal Disease; X-ray.<strong></strong></p><p> </p>


2022 ◽  
Author(s):  
Meri Hisamoto ◽  
Shunsuke Kimura ◽  
Kai Iwata ◽  
Toshihiko Iwanaga ◽  
Atsuro Yokoyama

Abstract Residual ridge resorption (RRR) is a chronic and progressive bone resorption following tooth loss. It causes deterioration of the oral environments and leads to the pathogenesis of various systemic diseases. However, the molecular mechanisms and risk factors for RRR progression are still unclear and controversial. In this study, we developed a tooth extraction model using mice for analyzing long-term morphological and gene expression changes in the alveolar bone. We further applied ovariectomy to this model to elucidate the effects of osteoporosis on RRR progression. As a result, the alveolar bone loss was biphasic and consisted of rapid loss in the early stages and subsequently slow and sustained bone loss over a long period. Gene expression analysis indicated that ovariectomy increased the expression of pro-inflammatory cytokines in the alveolar bone and prolonged the activation of osteoclasts same as histological analysis. Furthermore, the expressions of Tnfsf11 and Sema4d kept increasing for a long time in OVX mice. Administration of neutralization antibodies for receptor activator of NF-κB ligand (RANKL) effectively suppressed RRR. Similarly, inhibition of Semaphorin 4d (Sema4d) also improved alveolar bone loss. This study demonstrated that osteoporosis is a risk factor for RRR and that RANKL and Sema4d suppression are potential treatments.


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