scholarly journals A Longitudinal Study of Lipids and Blood Pressure in Relation to Method of Contraception in Latino Women With Prior Gestational Diabetes Mellitus

Diabetes Care ◽  
2007 ◽  
Vol 30 (8) ◽  
pp. 1952-1958 ◽  
Author(s):  
A. H. Xiang ◽  
M. Kawakubo ◽  
T. A. Buchanan ◽  
S. L. Kjos
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Longitudinal Study ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Latino Women

scholarly journals Prevalence of gestational diabetes mellitus and its correlation with blood pressure in Manipuri women

2013 ◽  
Vol 17 (6) ◽  
pp. 957 ◽  
Author(s):  
ThangjamPremchand Singh ◽  
Vanlalhruaii ◽  
Salam Ranabir ◽  
Lallan Prasad ◽  
NaoremNabakishore Singh
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus

scholarly journals Maternal GALNT2 Variations Affect Blood Pressure, Atherogenic Index, and Fetal Growth, Depending on BMI in Gestational Diabetes Mellitus

2021 ◽  
Vol 12 ◽  
Author(s):  
Linbo Guan ◽  
Ping Fan ◽  
Xinghui Liu ◽  
Mi Zhou ◽  
Yujie Wu ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Fetal Growth ◽  
Atherogenic Index ◽  
Dependent Manner ◽  
Nucleotide Polymorphisms ◽  
Genetic Associations ◽  
Genetic Components

BackgroundGALNT2 is a GalNAc transferase that regulates serum lipid fractions, insulin signaling, and lipogenesis. Genetic variants are implicated in the pathogenesis of gestational diabetes mellitus (GDM). The objective of this study was to investigate the association of GALNT2 rs2144300 and rs4846914 single nucleotide polymorphisms (SNPs) with the risk of GDM and related traits.MethodsTwo SNPs were genotyped, and clinical and metabolic parameters were determined in 461 GDM patients and 626 control subjects. Genetic associations with related traits were also analyzed.ResultsThe genotype distributions of the two SNPs in GDM patients were similar to those in normal controls. However, significant differences were noted across the three groups of genotypes with respect to the examined variables in subjects in a BMI-dependent manner. The rs4846914 and rs2144300 SNPs of GALNT2 were significantly associated with systolic blood pressure and/or diastolic blood pressure levels in nonobese GDM patients and atherogenic index (AI) in overweight/obese GDM patients. The rs4846914 SNP was also associated with fetal growth in overweight/obese GDM patients, and apo A1 and pregnancy weight gain in overweight/obese control women (all P<0.05).ConclusionsThe two polymorphisms in the GALNT2 gene are associated with variations in blood pressure, atherogenic index, and fetal growth in GDM, depending on BMI, but not with GDM. Our findings highlight a link between related phenotypes in GDM mothers and their fetuses and the genetic components.

Diabetes in pregnancy

2010 ◽  
pp. 2133-2139 ◽  
Author(s):  
Moshe Hod ◽  
Yariv Yogev
Keyword(s):  
Diabetes Mellitus ◽  
Blood Pressure ◽  
Glycaemic Control ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Vascular Disease ◽  
Peripheral Vascular Disease ◽  
Retinal Disease ◽  
Medical Complications ◽  
In Pregnancy

Diabetes is one of the most common medical complications in pregnancy: 0.4 to 2% of all births are complicated by pregestational diabetes; about 3% of pregnancies are complicated by gestational diabetes mellitus, with substantially more in some populations. Preconceptional evaluation—this should include evaluation of glycaemic control, blood pressure, retinal disease, renal status, thyroid function, peripheral and autonomic neuropathy, peripheral vascular disease, and hypoglyacemic symptoms....

Cardiovascular risk factors in offspring exposed to gestational diabetes mellitus in utero: systematic review and meta-analysis

2020 ◽  
Vol 11 (6) ◽  
pp. 599-616 ◽  
Author(s):  
Maleesa M. Pathirana ◽  
Zohra S. Lassi ◽  
Claire T. Roberts ◽  
Prabha H. Andraweera
Keyword(s):  
Diabetes Mellitus ◽  
Risk Factors ◽  
Systematic Review ◽  
Blood Pressure ◽  
Cardiovascular Risk ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Systolic Blood Pressure ◽  
Meta Analysis ◽  
In Utero

AbstractGestational diabetes mellitus (GDM) is a pregnancy complication that affects one in seven pregnancies. Emerging evidence demonstrates that children born of pregnancies complicated by GDM may be at increased risk of cardiovascular disease (CVD) in adulthood. Therefore, the aim of this study was to determine cardiovascular risk factors in offspring exposed to GDM in utero. PubMed, CINAHL, SCOPUS, and EMBASE databases were searched. Information was extracted on established CVD risk factors including blood pressure, lipids, blood glucose, fasting insulin, body mass index (BMI), and endothelial/microvascular function. The review protocol is registered in PROSPERO (CRD42018094983). Prospective and retrospective studies comparing offspring exposed to GDM compared to controls (non-GDM pregnancies) were considered. We included studies that defined GDM based on the International Association of Diabetes and Pregnancy Study Groups (IADPSG) definition, or prior definitions. The PRISMA guidelines were followed in conducting this systematic review. Methodological quality was assessed using the Newcastle–Ottawa Quality Assessment Scale. Study selection, data extraction, and quality assessment were done by two independent reviewers. The data were pooled using a random-effects model. Of 59 eligible studies, 24 were included in the meta-analysis. Offspring exposed to GDM had higher systolic blood pressure (mean difference (MD): 1.75 mmHg, 95% CI 0.57–2.94; eight studies, 7264 participants), BMI z-score (MD 0.11, 95% CI 0.02–0.20; nine studies, 8759 participants), and glucose (standard MD 0.43, 95% CI 0.08–0.77; 11 studies, 6423 participants) than control participants. In conclusion, offspring exposed to GDM have elevated systolic blood pressure, BMI, and glucose. Those exposed to GDM in utero may benefit from early childhood blood pressure measurements.

scholarly journals Vitamin D status during pregnancy and the risk of gestational diabetes mellitus: A longitudinal study in a multiracial cohort

2019 ◽  
Vol 21 (8) ◽  
pp. 1895-1905 ◽  
Author(s):  
Jin Xia ◽  
Yiqing Song ◽  
Shristi Rawal ◽  
Jing Wu ◽  
Stefanie N. Hinkle ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Vitamin D ◽  
Longitudinal Study ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Vitamin D Status

scholarly journals Plasma concentrations of lipids during pregnancy and the risk of gestational diabetes mellitus: A longitudinal study

2017 ◽  
Vol 10 (6) ◽  
pp. 487-495 ◽  
Author(s):  
Wei Bao ◽  
Sharon Dar ◽  
Yeyi Zhu ◽  
Jing Wu ◽  
Shristi Rawal ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Longitudinal Study ◽  
Gestational Diabetes ◽  
Gestational Diabetes Mellitus ◽  
Plasma Concentrations
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