Reliability and Validity of the Arabic Version of the EORTC QLQ-C30 and QLQ-BR23 Questionnaires

PURPOSE The European Organization for Research and Treatment of Cancer Core Quality of Life Questionnaire (EORTC QLQ-C30) is a well-validated instrument that assesses health-related quality of life (HRQOL) in cancer patients. It is used in cancer clinical trials in Europe, Canada, and the United States, and has demonstrated high reliability and validity in different groups of cancer patients. Despite thorough testing of reliability and validity, we have not identified any reports on its test/retest reliability; thus, a test/retest study was performed at the Norwegian Radium Hospital (NRH). MATERIALS AND METHODS Cancer patients from the outpatient clinic who were off treatment for > or = 3 months were eligible for the study. The EORTC QLQ-C30 was given to the patients when they presented for their visit. The second questionnaire was received by the patients 4 days later. Of 291 eligible patients, 270 (93%) agreed to participate and 190 (73%) completed both questionnaires. RESULTS The test/retest reliability measured by Pearson's correlation coefficient was high for all functional scales, with a range from .82 for cognitive and role function to .91 for physical function. The r value for global HRQOL was .85. For the symptom scales--nausea/vomiting, fatigue, and pain--the coefficients were .63, .83, and .86, respectively. The single-item coefficients ranged from .72 for diarrhea to .84 for financial impact. The Spearman rank correlation was in the same range for all dimensions. CONCLUSION The EORTC QLQ-C30 seems to yield high test/retest reliability in patients with various cancer diagnoses whose condition is not expected to change during the time of measurement.

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Reliability and validity of the EORTC QLQ-C30 in palliative care cancer patients

Open Medicine ◽

10.2478/s11536-009-0032-7 ◽

2009 ◽

Vol 4 (3) ◽

pp. 348-357 ◽

Cited By ~ 10

Author(s):

Hubert Jocham ◽

Theo Dassen ◽

Guy Widdershoven ◽

Ruud Halfens

Keyword(s):

Quality Of Life ◽

Palliative Care ◽

Cancer Patients ◽

Symptom Control ◽

Reliability And Validity ◽

European Organization ◽

Wide Range ◽

Eortc Qlq C30 ◽

Eortc Qlq

AbstractPalliative care aims at improving the patient’s quality of life. The assessment of this quality of life (QoL) is crucial for the evaluation of palliative care outcome. Many patients require hospital admissions for symptom control during their cancer journey and most of them die in hospitals, although they would like to stay at home until the end of their lives. In 1986, the European Organization for Research and Treatment (EORTC) initiated a research programme to develop an integrated, modular approach for evaluating the quality of life of patients participating in international clinical trials. This questionnaire measures cancer patients’ physical, psychological and social functions and was used in a wide range of clinical cancer trials with large numbers of research groups and also in various other non-trial studies. The aim of this study was to evaluate the psychometric properties, especially the reliability, validity and applicability of the EORTC QLQ-C30 in a German sample of terminally ill cancer patients receiving palliative care in different settings. The questionnaire was well accepted in the present patient population. Scale reliability was good (pre-treatment 0.80) especially for the functional scale. The results support the reliability and validity of the QLQ-C30 (version 3.0) as a measure of the health-related quality of life in German cancer patients receiving palliative care treatment.

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The feasibility, reliability and validity of the EORTC QLQ-C30 in assessing the quality of life of patients with a symptomatic HIV infection or AIDS (CDC IV)

Psychology and Health ◽

10.1080/08870449408407460 ◽

1994 ◽

Vol 9 (1-2) ◽

pp. 65-77 ◽

Cited By ~ 18

Author(s):

Josien B. De Boer ◽

Mirjam A.G. Sprangers ◽

Neil K. Aaronson ◽

Joep M.A. Lange ◽

Frits S.A.M. Van Dam

Keyword(s):

Quality Of Life ◽

Hiv Infection ◽

Reliability And Validity ◽

Eortc Qlq C30 ◽

Eortc Qlq

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Evaluation of reliability and validity of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30, Albanian version) among breast cancer patients from Kosovo

Patient Preference and Adherence ◽

10.2147/ppa.s78334 ◽

2015 ◽

pp. 459 ◽

Cited By ~ 5

Author(s):

Selvete Shuleta-Qehaja ◽

Zoran Sterjev ◽

Ljubica Shuturkova

Keyword(s):

Breast Cancer ◽

Quality Of Life ◽

Reliability And Validity ◽

Life Questionnaire ◽

Breast Cancer Patients ◽

European Organization ◽

Quality Of Life Questionnaire ◽

Eortc Qlq C30 ◽

Eortc Qlq

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Reliability and validity of the Arabic translation of the palliative performance scale

Palliative & Supportive Care ◽

10.1017/s1478951519000889 ◽

2019 ◽

Vol 18 (5) ◽

pp. 575-579

Author(s):

Ahmed A.M. Abdelhafeez ◽

Nafie F. Makady ◽

Ola Hafez ◽

Catherine N. Atallah ◽

Samy A. Alsirafy

Keyword(s):

Supportive Care ◽

Cancer Patients ◽

Palliative Chemotherapy ◽

Reliability And Validity ◽

Best Supportive Care ◽

Life Questionnaire ◽

Arabic Translation ◽

Eortc Qlq C30 ◽

Eortc Qlq ◽

Performance Scale

AbstractObjectiveThe aim of this study was to translate the Palliative Performance Scale (PPSv2) into Arabic and to test the reliability and validity of the PPS Arabic translation (PPS-Arabic).MethodThe PPSv2 was translated into Modern Standard Arabic using a forward–backward method. Inter-rater and intra-rater reliabilities were tested in a pilot study that included 20 patients. The validation study included 150 cancer patients. Patients were divided according to their treatment plan into three groups (in-remission, palliative chemotherapy, and best supportive care) to perform hypothesis-testing construct validity. Validity was further evaluated by correlating PPS-Arabic with the Karnofsky Performance Scale (KPS), the Eastern Cooperative Oncology Group (ECOG) scale, and Physical Functioning (PF2) and Role Functioning (RF2) scales of the European Organization for Research and Treatment of Cancer quality of life questionnaire (EORTC QLQ-C30).ResultsThe intraclass correlation coefficients for the intra-rater and inter-rater reliability were 0.935 (95% CI: 0.88–0.965; p < 0.001) and 0.965 (95% CI: 0.934–0.981; p < 0.001), respectively. The PPS-Arabic internal consistency Cronbach's alpha was 0.986. The average PPS-Arabic score differed significantly (p < 0.001) between the three groups of patients being 89 for in-remission, 58 for palliative chemotherapy, and 38 for best supportive care. The PPS-Arabic score correlated significantly (p < 0.001) with the KPS, ECOG performance scale, and the EORTC QLQ-C30 PF2 and RF2 scales.ConclusionThe PPS-Arabic is a reliable and valid tool for the assessment of performance status of cancer patients.

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eCross-cultural adaptation of the spine oncology-specific SOSGOQ2.0 questionnaire to German language and the assessment of its validity and reliability in the clinical setting

BMC Cancer ◽

10.1186/s12885-021-08578-x ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

T. Datzmann ◽

W. Kisel ◽

J. Kramer ◽

M. Dreimann ◽

J. D. Müller-Broich ◽

...

Keyword(s):

Construct Validity ◽

Physical Functioning ◽

Cultural Adaptation ◽

Reliability And Validity ◽

Cross Cultural ◽

German Language ◽

Cross Cultural Adaptation ◽

Eortc Qlq C30 ◽

The Cross ◽

Eortc Qlq

Abstract Background The recently developed Spine Oncology Study Group Outcomes Questionnaire (SOSGOQ2.0) was proven a valid and reliable instrument measuring health-related quality of life (HRQOL) for patients with spinal malignancies. A German version was not available. Objective A cross-cultural adaptation of the SOSGOQ2.0 to the German language and its multicenter evaluation. Methods In a multistep process, a cross-cultural adaptation of the SOSGOQ2.0 was conducted. Subsequently, a multicenter, prospective observational cohort study was initiated to assess the reliability and validity of the German adaptation. To assess external construct validity of the cross-cultural adapted questionnaire, a comparison to the established questionnaire QLQ-C30 from the European Organisation for Research and Treatment of Cancer was conducted. Mean-difference plots were used to measure the agreement between the questionnaires in total score and by domain (deviation from mean up to 10% allowed). Further reliability and validity tests were carried out. Change to baseline was analysed 3–16 weeks later after different interventions occurred. Clinically relevant thresholds in comparison to the EORTC QLQ-C30 questionnaire were evaluated by ROC curve analysis. Results We could enroll 113 patients from four different university hospitals (58 females, 55 males). Mean age was 64.11 years (sd 11.9). 80 patients had an ECOG performance status of 2 or higher at baseline. External construct validity in comparison to the EORTC QLQ-C30 questionnaire in total score and by domain was confirmed (range of deviation 4.4 to 9.0%). Good responsiveness for the domains Physical Functioning (P < .001) and Pain (P < .001) could be shown. The group mean values also displayed a difference in the domains of Social Functioning (P = .331) and Mental Health (P = .130), but not significant. The minimum clinically relevant threshold values for the questionnaire ranged from 4.0 to 7.5 points. Conclusions According to our results, the cross-cultural adapted questionnaire is a reliable and valid tool to measure HRQOL in German speaking patients with spinal malignancies. Especially the domains Physical Functioning and Pain showed overall good psychometric characteristics. In this way, a generic questionnaire, such as the EORTC QLQ-C30, can be usefully supplemented by spine-specific questions to increase the overall accuracy measuring HRQOL in patients with spinal malignancies.

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Comparison of the EORTC QLQ-C30 and the HPN-QOL in long term HPN-patients

Aktuelle Ernährungsmedizin ◽

10.1055/s-0030-1254602 ◽

2010 ◽

Vol 35 (03) ◽

Author(s):

P Thul

Keyword(s):

Eortc Qlq C30 ◽

Eortc Qlq

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Psychometric validation of the Moroccan version of the EORTC QLQ-C30 in colorectal Cancer patients: cross-sectional study and systematic literature review

BMC Cancer ◽

10.1186/s12885-021-07793-w ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Yacir El Alami ◽

Hajar Essangri ◽

Mohammed Anass Majbar ◽

Saber Boutayeb ◽

Said Benamr ◽

...

Keyword(s):

Quality Of Life ◽

Colorectal Cancer ◽

Discriminant Validity ◽

Cross Sectional Study ◽

Cross Sectional ◽

Related Quality ◽

Eortc Qlq C30 ◽

Eortc Qlq ◽

Colorectal Cancer Patients

Abstract Background Health-related quality of life is mainly impacted by colorectal cancer which justified the major importance addressed to the development and validation of assessment questionnaires. We aimed to assess the validity and reliability of the Moroccan Arabic Dialectal version of the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Core Questionnaire (QLQ-C30) in patients with colorectal cancer. Methods We conducted a cross-sectional study using the Moroccan version of the EORTC QLQ-C30 on colorectal cancer patients from the National Oncology Institute of Rabat, in the period from February 2015 to June 2017. The QLQ-C30 was administered to 120 patients. Statistical analysis included reliability, convergent, and discriminant validity as well as known-groups comparisons. Results In total, 120 patients with colorectal cancer were included in the study with 38 (32%) patients diagnosed with colon cancers. Eighty-two patients (68%) had rectal cancer, among which 29 (24%) patients with a stoma. The mean age of diagnosis was 54 years (+/− 13.3). The reliability and validity of the Arabic dialectal Moroccan version of the EORTC QLQ-C30 were satisfactory. [Cronbach’s alpha (α =0.74)]. All items accomplished the criteria for convergent and discriminant validity except for question number 5, which did not complete the minimum required correlation with its own scale (physical functioning). Patients with rectal cancer presented with bad Global health status and quality of life (GHS/QOL), emotional functioning as well as higher fatigue symptoms compared to patients with colon cancer. The difference between patients with and without stoma was significant for diarrhea and financial difficulty. Conclusions The Moroccan Arabic Dialectal version of the QLQ-C30 is a valid and reliable measure of health-related quality of life (HRQOL) in patients with colorectal cancer.

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