scholarly journals Protective effect of maternal vitamin E supplementation on phenytoin-induced teratogenicity in rat pups

2015 ◽  
Vol 9 (1) ◽  
pp. 1-12 ◽  
Author(s):  
Tarek M Essa ◽  
Attia M Gabr ◽  
Abd El-Rahman E Mohamed ◽  
Abdel-Raheim M A Meki
Keyword(s):  
Vitamin E ◽  
Protective Effect ◽  
Maternal Vitamin ◽  
Rat Pups ◽  
Vitamin E Supplementation

scholarly journals Protective effect of vitamin E supplementation on increased thermal stability of collagen in diabetic rats

Diabetologia ◽  
1992 ◽  
Vol 35 (10) ◽  
pp. 913-916 ◽  
Author(s):  
Y. Aoki ◽  
Y. Yanagisawa ◽  
K. Yazaki ◽  
H. Oguchi ◽  
K. Kiyosawa ◽  
...  
Keyword(s):  
Thermal Stability ◽  
Vitamin E ◽  
Protective Effect ◽  
Diabetic Rats ◽  
Thermal Stability Of ◽  
Vitamin E Supplementation

Protective effect of vitamin E on exercise-induced oxidative damage in young and older adults

1993 ◽  
Vol 264 (5) ◽  
pp. R992-R998 ◽  
Author(s):  
M. Meydani ◽  
W. J. Evans ◽  
G. Handelman ◽  
L. Biddle ◽  
R. A. Fielding ◽  
...  
Keyword(s):  
Vitamin E ◽  
Oxidative Damage ◽  
Protective Effect ◽  
Eccentric Exercise ◽  
Conjugated Dienes ◽  
Alpha Tocopherol ◽  
Double Blind ◽  
Tocopherol Concentration ◽  
Exercise Induced ◽  
Vitamin E Supplementation

The protective effect of vitamin E supplementation on exercise-induced oxidative damage was tested in 21 male volunteers. Nine young (22-29 yr) and 12 older (55-74 yr) sedentary male subjects participated in a double-blind protocol and received either 800 IU dl-alpha-tocopherol or a placebo daily. After 48 days, vitamin E supplementation significantly increased alpha-tocopherol in plasma and skeletal muscle. Subjects then performed a bout of eccentric exercise at 75% of their maximum heart rate by running down an inclined treadmill for 45 min. All vitamin E-supplemented subjects excreted less (P < 0.05) urinary thiobarbituric acid adducts after the exercise bout than placebo subjects at 12 days postexercise (35 and 18% above baseline in young and old supplemented groups, respectively, vs. 60 and 80% in young and old placebo groups, respectively). After exercise, the initial difference in alpha-tocopherol concentration of muscle between young placebo and vitamin E-supplemented groups was diminished and muscle lipid conjugated dienes tended to increase (P = 0.09) in placebo subjects. Placebo subjects had a significant decrease in major fatty acids of muscle biopsy taken immediately after exercise. When normalized for the hemoconcentration effects of exercise, the plasma concentration of vitamins E and C and uric acid showed no significant change. The alterations in fatty acid composition, vitamin E, and lipid conjugated dienes in muscle and in urinary lipid peroxides in controls after eccentric exercise are consistent with the concept that vitamin E provides protection against exercise-induced oxidative injury.

scholarly journals Maternal Vitamin E Supplementation Affects the Antioxidant Capability and Oxidative Status of Hatching Chicks

2005 ◽  
Vol 135 (10) ◽  
pp. 2457-2461 ◽  
Author(s):  
Yih-Fwu Lin ◽  
Hsiu-Ling Tsai ◽  
Yi-Chun Lee ◽  
Sue-Joan Chang
Keyword(s):  
Vitamin E ◽  
Oxidative Status ◽  
Maternal Vitamin ◽  
Vitamin E Supplementation

scholarly journals Dietary vitamin E supplementation on cholesterol and cholesterol oxides of pig meat and cooked ham

2006 ◽  
Vol 49 (2) ◽  
pp. 197-205 ◽  
Author(s):  
Vera Lúcia Ferreira de Souza ◽  
Rui Sérgio S. Ferreira da Silva
Keyword(s):  
Vitamin E ◽  
Protective Effect ◽  
Control Diet ◽  
Dietary Vitamin ◽  
Cholesterol Oxides ◽  
Associated Production ◽  
Cholesterol Levels ◽  
Cooked Ham ◽  
Pig Meat ◽  
Vitamin E Supplementation

Objective of this work was to evaluate the protective effect of vitamin E on the cooked ham. Ninety-six pigs (LW X L X P), forty-eight barrows and forty-eight gilts were divided in four randomized blocks. Each block received four treatments: a control diet, diets formulated with 100 mg, with 200 mg and with 400 mg of vitamin E/kg diet. The average cholesterol values in cooked ham were 46.53 ± 0.47 mg/100g. However, a reduction of 30% was observed in samples of supplemented diets with 400 mg of vitamin E/kg. During shelf-life of the cooked ham was observed a reduction in the cholesterol levels, with the associated production of cholesterol oxides. The cholesterol oxides observed were: cholesta-4,6-dien-3-one; 20alpha-hydroxycolesterol; 24-hydroxycholesterol, and 25-hidroxycholesterol. Supplementation of 200 mg of vitamin E/kg or more maintained the cholesterol oxides values below 10 µg/g during the 116 days before slaughter.

Has high-dose vitamin E supplementation a protective effect during open heart surgery?

1990 ◽  
Vol 9 ◽  
pp. 44
Author(s):  
P.E. Balimer ◽  
W.H. Reinhart ◽  
P. Jordan ◽  
E. Bühler ◽  
U. Moser ◽  
...  
Keyword(s):  
Vitamin E ◽  
Protective Effect ◽  
Heart Surgery ◽  
Open Heart Surgery ◽  
High Dose ◽  
Open Heart ◽  
High Dose Vitamin ◽  
Vitamin E Supplementation

Protective Effect of Vitamin E on Immune Triggered, Granulocyte Mediated Endothelial Injury

1984 ◽  
Vol 51 (01) ◽  
pp. 089-092 ◽  
Author(s):  
M A Boogaerts ◽  
J Van de Broeck ◽  
H Deckmyn ◽  
C Roelant ◽  
J Vermylen ◽  
...  
Keyword(s):  
Vitamin E ◽  
Protective Effect ◽  
Umbilical Vein ◽  
Endothelial Damage ◽  
Endothelial Injury ◽  
Mediated Effects ◽  
Anti Oxidant ◽  
Endothelial Cell Cultures ◽  
Vitro Model

SummaryThe effect of alfa-tocopherol on the cell-cell interactions at the vessel wall were studied, using an in vitro model of human umbilical vein endothelial cell cultures (HUEC). Immune triggered granulocytes (PMN) will adhere to and damage HUEC and platelets enhance this PMN mediated endothelial injury. When HUEC are cultured in the presence of vitamin E, 51Cr-leakage induced by complement stimulated PMN is significantly decreased and the enhanced cytotoxicity by platelets is completely abolished (p <0.001).The inhibition of PMN induced endothelial injury is directly correlated to a diminished adherence of PMN to vitamin E- cultured HUEC (p <0.001), which may be mediated by an increase of both basal and stimulated endogenous prostacyclin (PGI2) from alfa-tocopherol-treated HUEC (p <0.025). The vitamin E-effect is abolished by incubation of HUEC with the irreversible cyclo-oxygenase inhibitor, acetylsalicylic acid, but the addition of exogenous PGI2 could not reproduce the vitamin E-mediated effects.We conclude that vitamin E exerts a protective effect on immune triggered endothelial damage, partly by increasing the endogenous anti-oxidant potential, partly by modulating intrinsic endothelial prostaglandin production. The failure to reproduce vitamin E-protection by exogenously added PGI2 may suggest additional, not yet elucidated vitamin E-effects on endothelial metabolism.

Vitamin E supplementation in the treatment of Graves' disease

2013 ◽  
Author(s):  
Mirela Sanda Petrulea ◽  
Ioana Ilie ◽  
Ana Valea ◽  
Cristina Ghervan ◽  
Carmen Georgescu ◽  
...  
Keyword(s):  
Vitamin E ◽  
Graves Disease ◽  
Vitamin E Supplementation
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