scholarly journals Nonseminomatous Germ Cell Testicular Tumour With Metastatic Retroperitoneal Lymphadenopathy Presenting As Severe Backache Due To Ivc Thrombosis

Author(s):  
Sanjay M. Khaladkar ◽  
Rubab Kaur Sekhon ◽  
Khushboo Agrawal ◽  
Vikas Lilabai Jadhav ◽  
Rajesh S. Kuber

IVC thrombosis is often under-recognized. Malignancy can cause spontaneous IVC thrombosis due to its prothrombotic potential. Malignant tumors can compress, adhere or infiltrate the IVC wall causing endothelial damage with subsequent thrombosis. Retroperitoneal lymphadenopathy can cause compressive distortion of IVC causing venous stasis and turbulent flow. Metastatic retroperitoneal lymphadenopathy from testicular tumor is a rare cause of IVC invasion with resultant IVC thrombosis which can rarely present as backache. High index of suspicion is needed to detect primary testicular tumor in cases of IVC thrombosis, especially in young individuals. A 26 -year old male presented with lower back ache, weight loss and fever. MRI Lumbosacral spine done outside showed a soft tissue signal intensity retroperitoneal mass in aortocaval region compressing IVC. Ultrasound (done outside) revealed mild right sided hydroureteronephrosis secondary to a lobulated heterogeneous mass in inter-aortocaval region encasing right ureter and invading IVC causing thrombosis. Contrast enhanced Computerized axial tomography of abdomen showed a heterogeneously enhancing lobulated mass with multiple internal calcifications, in inter-aortocaval region at L3-4 level invading the IVC causing IVC thrombosis. Both tumor thrombus and bland thrombus were present. The right testis showed a subtle 10x10 mm hypodense lesion with peripheral calcification. DW-MRI showed diffusion restriction in retroperitoneal mass and the IVC tumor thrombus. Possibility of primary testicular tumor with metastatic retroperitoneal lymphadenopathy causing IVC invasion with resultant thrombosis was considered which was confirmed on histopathology examination. 

2011 ◽  
Vol 2011 ◽  
pp. 1-2 ◽  
Author(s):  
M. S. Papageorgiou ◽  
G. Dadakas ◽  
K. Donev

Liposarcomas are malignant tumors derived embryologically from mesodermal tissues. An unusual site of presentation is the spermatic cord, presenting as an inguinal or scrotal mass. We report a rare case of a liposarcoma of the spermatic cord, mimicking a testicular tumor. The patient was operated, and an orchidectomy, including the tumor, was performed. To our knowledge, there are about 185 similar cases reported in the literature.


ANALES RANM ◽  
2021 ◽  
Vol 138 (138(02)) ◽  
pp. 183-185
Author(s):  
M.K. Meneses Navas ◽  
P. Romero Fernández ◽  
M.N. Cabrera Martín ◽  
A. Ortega Candil ◽  
J.L. Carreras Delgado

Tuberculosis is an infectious disease, caused by the Mycobacterium tuberculosis bacillus. Extrapulmonary disease can cause nonspecific symptoms and signs, which makes diagnostic suspicion difficult. We present the case of a man with a history of cancer in complete remission, diagnosed with lymph node tuberculosis, after being admitted to our hospital due to fever, dyspnea, and central chest pain. A Positron Emission Tomography / Computed Axial Tomography with 18F-fluordexosiglucose is requested; which showed multiple mediastinal adenopathic conglomerates with intense radiotracer uptake, suggesting ruling out malignancy. Active lymph node tuberculosis will show increased metabolic activity with Positron Emission Tomography / Computed Tomography with 18F-fluordexosiglucose, which could make the differential diagnosis with malignant tumors or other granulomatous diseases difficult, as in the case of our patient. Therefore, it is important to consider lymph node tuberculosis as a differential diagnosis in patients with adenopathies suspected of malignancy.


2002 ◽  
Vol 12 (9) ◽  
pp. 326-331 ◽  
Author(s):  
Agnes Arnold

In last month's BJPN, Agnes Arnold discussed the pathophysiology of deep vein thrombosis and suggested ways that the risk could be reduced, particularly with respect to DVTs resulting from endothelial damage in surgery. In this, the second of a two-part series, Agnes continues by looking at hypercoagulability of blood and venous stasis and the impact of these conditions on the risk of DVT.


Immunotherapy ◽  
2021 ◽  
Author(s):  
Xuhong Liu ◽  
Yong Yi

Hepatocellular carcinoma is one of the most common malignant tumors in China and is also a major cause of cancer deaths worldwide. Recent advances in immunotherapy have identified new treatments in which immunotherapy can be combined with antiangiogenic therapy. We report a case of hepatocellular carcinoma with a tumor thrombus at the inferior vena cava–right atrium junction and multiple lung metastases after a multiple-course treatment. Treatment with sintilimab in combination with sorafenib led to a partial remission and immune-related hepatitis.


2021 ◽  
Vol 10 (4) ◽  
pp. 3280-3283
Author(s):  
Madhura Darware

Sacralization is an embryo congenital defect in which the fifth lumbar vertebra is fused to the sacrum in various degrees. The prevalence of sacralization is 7.5 percent. Sacralization can be unilateral or bilateral. This disorder arises due to irregularities in the lumbosacral spine segmentation during development. Transverse process of the L5 on one side or both sides is wider than usual and fuses into the sacrum or ilium or both in the sacralization of the fifth lumbar vertebra. Low back pain is the most common symptom in most of the population throughout their lifetime. As low back pain is a leading cause of disability, interfering with quality of life and job outcomes our goal is to assess the association between sacralisation and low back pain. Purpose: To study the relationship between sacralization and low back pain. Because the role of sacralization throughout causing LBP is still controversial. This is the observational study which includes 55 participants who have low back ache. The participants are between the ages 60 to 70 years. The intensity of pain was assessed through NPRS. To assess the relationship between Sacralization and low back pain, all the participants were sent for Xray and the presence of Sacralization was assessed by X-ray. We found that there was a significant relationship between sacralization and low back pain. The patients with sacralization show the high intensity of low back pain. We concluded that Sacralization affects the lumbosacral spine in different ways and result in pain in lower back. And there is significant association of sacralization with low back ache.


2003 ◽  
Vol 35 (2) ◽  
pp. 201-202
Author(s):  
Ali Ünsal ◽  
Ersin Cimentepe ◽  
Bunyamin Isık ◽  
Selda Tez ◽  
Ziya Akbulut ◽  
...  

2013 ◽  
Vol 70 (7) ◽  
pp. 693-696 ◽  
Author(s):  
Filip Vukmirovic ◽  
Nihad Zejnilovic ◽  
Jovan Ivovic

Introduction. Liposarcomas are malignant tumors derived from fat tissues. Liposarcoma of the paratesticular tissue is rare. Case report. We presented a 51-year-old man with liposarcoma of paratesticular tissue and the spermatic cord, mimicking a testicular tumor. Ultrasound examination of this scrotal mass was hyperechogenic and homogeneous and separated from the testis and epididymis. The patient was operated, and the orchidectomy was performed. Histology revealed well-differentiated lipoma-like liposarcoma of the paratesticular tissue and spermatic cord. After a 6 month follow-up the patient did not show any evidence of tumor-progression or recurrence. Conclusion. Liposarcomas of the paratesticular tissue and seminal cord represent a rare type of tumors, often misdiagnosed preoperatively. Therapy should include radical surgical excision, usually radical inguinal orchiectomy. If the margin status is in doubt, adjuvant radiation should be performed. Local relapse is common and may occur after several years, so follow- up period has to be sufficiently long.


2020 ◽  
Vol 6 (1) ◽  
Author(s):  
Daisuke Udagawa ◽  
Motohide Shimazu ◽  
Tadayuki Sakuragawa ◽  
Shotaro Maruyama ◽  
Yusuke Uchi ◽  
...  

Abstract Background The portal vein is occasionally invaded by advanced malignant tumors in the pancreatic head region. However, pancreatic cancer rarely has portal vein tumor thrombi. We report a case of pancreatic cancer with a massive portal vein tumor thrombus undergoing pancreatoduodenectomy with combined resection of the portal vein. Case presentation A 71-year-old man visited a clinic with complaints of abdominal discomfort and vomiting. Gastroscopy showed a massive tumor in the duodenum. He was referred to our hospital for further examinations and treatment. The CT showed a low-density tumor with a maximum diameter of 10 cm located on the pancreas head. A tumor widely invaded the duodenum and had a 6-cm portal vein tumor thrombus. MRCP did not show obvious stenosis of the pancreatic duct due to tumor invasion. There were no findings suggesting distant metastases. Biopsy of the duodenum revealed adenocarcinoma. He was diagnosed with primary pancreatic cancer or duodenal cancer with portal vein tumor thrombus and underwent pancreatoduodectomy with resection and reconstruction of the portal vein. He suffered no postoperative complications and was discharged 2 months after surgery. The final histopathological diagnosis was pancreatic colloid carcinoma. He received adjuvant chemotherapy, but died 16 months after surgery. Conclusions Colloid carcinoma of the pancreas is rare, and pancreatic carcinoma seldom forms a portal vein tumor thrombus. We experienced a very rare case of pancreatic colloid carcinoma with portal vein tumor thrombus and performed radical resection of the pancreas and portal vein.


2018 ◽  
Vol 2018 ◽  
pp. 1-4
Author(s):  
Hirotake Kodama ◽  
Shingo Hatakeyama ◽  
Teppei Matsumoto ◽  
Toshikazu Tanaka ◽  
Hirotaka Horiguchi ◽  
...  

A paratesticular fibrous pseudotumor is a relatively rare benign disease. Preoperatively diagnosing a fibrous pseudotumor is challenging because distinguishing these masses from malignant tumors on the basis of clinical and radiological findings can be difficult. We present a case of a 28-year-old man who presented with a painless palpable mass in the right scrotum; the fibrous pseudotumor of the tunica vaginalis was treated with organ-sparing surgery. Computed tomography and magnetic resonance imaging revealed paratesticular tumors. Testicular tumor marker levels were within normal limits. We scheduled the patient to undergo tumor biopsy combined with intraoperative rapid diagnosis. Frozen section assessment suggested a fibrous pseudotumor without malignancy. We successfully performed organ-sparing surgery. Testicular-sparing surgery combined with frozen section assessment is primarily used for treating paratesticular fibrous pseudotumors.


2010 ◽  
pp. 2116-2120
Author(s):  
I.A. Greer

Aetiology—features that predispose to venous thromboembolism include (1) pregnancy is a thrombophilic state; (2) there is relative venous stasis during pregnancy; and (3) some endothelial damage to the pelvic vessels occurs during delivery. Epidemiology— venous thromboembolism complicates around 1 in 1000 pregnancies, with highest risk just after delivery. Deep venous thromboses usually occur on the left side, and a much higher proportion are ileofemoral than in patients who are not pregnant....


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