Preoperative risk factors in elderly patients undergoing aortic valve replacement

Author(s):  
I.I. Skopin ◽  
A.M. Otarov
Author(s):  
I.I. Skopin ◽  
A.M. Otarov ◽  
T.V. Asatryan ◽  
P.V. Kakhktsyan ◽  
Sh.M. Kurbanov

2019 ◽  
Vol 7 (4S) ◽  
pp. 24-35
Author(s):  
I. I. Skopin ◽  
A. M. Otarov ◽  
P. V. Kakhktsyan ◽  
T. V. Asatryan ◽  
Sh. M. Kurbanov ◽  
...  

Background.Despite an increase in the number of surgeries performed in elderly patients, conventional aortic valve replacement is associated with high postoperative mortality in comparison to young adults. The risk of surgical intervention in elderly patients is associated not only with the age, but also with the presence of a large number of concomitant diseases.Aim.To evaluate the immediate results of conventional aortic valve replacement and assess the impact of preoperative risk factors on surgical treatment.Methods.A retrospective analysis of the results of aortic valve replacement was performed in patients older than 65 years operated in the period from 2011 to 2015 (a total of 253 cases). The mean age of the patients was 70.4±4.14 years. The mean EuroSCORE was 6.09±4.45%. The impact of more than 30 preoperative risk factors on the in-hospital mortality and development of postoperative complications has been analyzed.Results.The overall in-hospital mortality was 10.3%. In-hospital mortality of isolated aortic valve replacement was 4.8%. In-hospital mortality of aortic valve replacement combined with coronary artery bypass grafting was 8.8%. High postoperative mortality rate was reliably associated with the urgency of surgery, a positive history of stroke, obesity, chronic renal failure, chronic obstructive pulmonary disease, pulmonary hypertension, a positive history of malignant neoplasms, polyvascular disease, pre-operative atrial fibrillation, IV class NYHA, post-stenotic aortic dilation, severe calcification, small aortic root.Conclusion.Aortic valve replacement in elderly and advanced age patients have relatively similar results to those of the younger patients. High risk of surgery in advanced age patients is mainly associated with the presence of concomitant extracardiac pathology and preoperative risk factors.


2013 ◽  
Vol 19 (5) ◽  
pp. 368-374 ◽  
Author(s):  
Mitsuharu Hosono ◽  
Yasuyuki Sasaki ◽  
Hidekazu Hirai ◽  
Masanori Sakaguchi ◽  
Atsushi Nakahira ◽  
...  

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Lytfi Krasniqi ◽  
Mads P. Kronby ◽  
Lars P. S. Riber

Abstract Background This study describes the long-term survival, risk of reoperation and clinical outcomes of patients undergoing solitary surgical aortic valve replacement (SAVR) with a Carpentier-Edwards Perimount (CE-P) bioprosthetic in Western Denmark. The renewed interest in SAVR is based on the questioning regarding the long-term survival since new aortic replacement technique such as transcatheter aortic-valve replacement (TAVR) probably have shorter durability, why assessment of long-term survival could be a key issue for patients. Methods From November 1999 to November 2013 a cohort of a total of 1604 patients with a median age of 73 years (IQR: 69–78) undergoing solitary SAVR with CE-P in Western Denmark was obtained November 2018 from the Western Danish Heart Registry (WDHR). The primary endpoint was long-term survival from all-cause mortality. Secondary endpoints were survival free from major adverse cardiovascular and cerebral events (MACCE), risk of reoperation, cause of late death, patient-prothesis mismatch, risk of AMI, stroke, pacemaker or ICD implantation and postoperative atrial fibrillation (POAF). Time-to-event analysis was performed with Kaplan-Meier curve, cumulative incidence function was performed with Nelson-Aalen cumulative hazard estimates. Cox regression was applied to detect risk factors for death and reoperation. Results In-hospital mortality was 2.7% and 30-day mortality at 3.4%. The 5-, 10- and 15-year survival from all-cause mortality was 77, 52 and 24%, respectively. Survival without MACCE was 80% after 10 years. Significant risk factors of mortality were small valves, smoking and EuroSCORE II ≥4%. The risk of reoperation was < 5% after 7.5 years and significant risk factors were valve prosthesis-patient mismatch and EuroSCORE II ≥4%. Conclusions Patients undergoing aortic valve replacement with a Carpentier-Edwards Perimount valve shows a very satisfying long-term survival. Future research should aim to investigate biological valves long-term durability for comparison of different SAVR to different TAVR in long perspective.


2000 ◽  
Vol 48 (4) ◽  
pp. 222-228 ◽  
Author(s):  
Shigeaki Ohtake ◽  
Yoshiki Sawa ◽  
Taichi Sakaguchi ◽  
Motonobu Nishimura ◽  
Hisashi Satoh ◽  
...  

2007 ◽  
Vol 83 (6) ◽  
pp. 2050-2053 ◽  
Author(s):  
Tohru Takaseya ◽  
Takemi Kawara ◽  
Shigehiko Tokunaga ◽  
Michitaka Kohno ◽  
Yasuhisa Oishi ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document