scholarly journals Complications of Chickenpox in Bulgaria – Data from a Single-Center Experience

2021 ◽  
Vol 48 (2) ◽  
pp. 37-40
Author(s):  
M. Popov ◽  
S. Antonov ◽  
V. Velev ◽  
T. Tcherveniakova ◽  
N. Yancheva
Keyword(s):  
Bacterial Infections ◽  
Soft Tissues ◽  
University Hospital ◽  
Parasitic Diseases ◽  
Varicella Zoster ◽  
Single Center Experience ◽  
Acute Enteritis ◽  
One Year ◽  
The University ◽  
Varicella Zoster Infection

Abstract Primary Varicella zoster infection (chickenpox) in childhood is a common benign disease. The predominance of uncomplicated cases in children often overshadows the rarer cases of complicated severe course of the disease. Objective To study the complications of primary chickenpox in hospitalized patients for a period of one year. Materials and Methods 122 patients with complicated primary chickenpox with an average age of 18.6 years; 57 males (46.7%) and 64 females (53.3%), were hospitalized at the University Hospital of Infectious and Parasitic Diseases “Prof. Iv. Kirov” in the period January – December 2019. Results The bacterial infections of the skin and soft tissues comprised the largest relative frequenchy – they occurred in 74 (60.6%) of the patients; followed by pneumonia – in 31 (25.4%) patients, and a combination of pneumonia and pustulation – in 10 (8.2%) patients. Cerebelitis was observed in 1 (0.8%) patient. One of the patients developed hepatitis, purulent arthritis and acute enteritis. We also report the death of one patient. Conclusions We registered a relatively high proportion of hospitalizations, especially in young children and adults. Regarding the type of complications, we do not describe significant differences compared to other authors. Although in most cases primary chickenpox is a self-limiting disease, complications are more common in the countries where there is no vaccine.

Prospective evaluation for gastrointestinal bleedings at the University Hospital St. Pölten – one year of follow-up

2019 ◽  
Author(s):  
M Stättermayer ◽  
F Riedl ◽  
S Bernhofer ◽  
A Stättermayer ◽  
A Mayer ◽  
...  
Keyword(s):  
University Hospital ◽  
Prospective Evaluation ◽  
One Year ◽  
The University

scholarly journals Meningitis gone viral: Description of the German Echo Wave 2013

2019 ◽  
Author(s):  
Jonas Graf ◽  
Christian Hartmann ◽  
Helmar C Lehmann ◽  
Carolin Otto ◽  
Ortwin Adams ◽  
...  
Keyword(s):  
Aseptic Meningitis ◽  
University Hospital ◽  
Cerebrospinal Fluid Analysis ◽  
Enteroviral Infection ◽  
Varicella Zoster ◽  
Fluid Analysis ◽  
Significant Burden ◽  
Simplex Virus ◽  
Herpes Simplex Virus 2 ◽  
The University

Abstract BACKGROUND: Aseptic meningitis epidemics may pose various health care challenges. OBJECTIVE: We describe the German enterovirus meningitis epidemics in the university hospital centers of Düsseldorf, Cologne and Berlin between January 1st and December 31st, 2013. RESULTS: A total of 72 enterovirus (EV-positive) meningitis cases were detected in our multicenter cohort, corresponding to 2.1% of all EV-positive cases which were voluntarily reported within the National Enterovirussurveillance (based on investigation of patients with suspected aseptic meningitis/encephalitis and acute flaccid paralysis) by physicians within this period of time. Among these 72 patients, 38 (52.8%) were echovirus-positive (18 pediatric and 20 adult cases, median age 18.5 years). At the same time, 45 aseptic meningitis cases in our cohort were excluded to be due to enteroviral infection (EV-negative). Three EV-negative patients were tested positive for varicella zoster virus (VZV) and one EV-negative patient for herpes simplex virus 2. Hospitalization was significantly longer in EV-negative cases. Cerebrospinal fluid analysis did not reveal significant differences between the two groups. After discharge, EV-meningitis resulted in significant burden of sick leave in our pediatric cohort as parents had to care for the children at home. CONCLUSION: Voluntary disease-specific surveillance, such as provided by the National Enterovirussurveillance in our study may be a valuable tool for epidemiological research.

scholarly journals Meningitis gone viral: description of the echovirus wave 2013 in Germany

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Jonas Graf ◽  
Christian J. Hartmann ◽  
Helmar C. Lehmann ◽  
Carolin Otto ◽  
Ortwin Adams ◽  
...  
Keyword(s):  
Aseptic Meningitis ◽  
University Hospital ◽  
Enteroviral Infection ◽  
Echovirus 30 ◽  
Varicella Zoster ◽  
Fluid Analysis ◽  
Significant Burden ◽  
Simplex Virus ◽  
Herpes Simplex Virus 2 ◽  
The University

Abstract Background Aseptic meningitis epidemics may pose various health care challenges. Methods We describe the German enterovirus meningitis epidemics in the university hospital centers of Düsseldorf, Cologne and Berlin between January 1st and December 31st, 2013 in order to scrutinize clinical differences from other aseptic meningitis cases. Results A total of 72 enterovirus (EV-positive) meningitis cases were detected in our multicenter cohort, corresponding to 5.8% of all EV-positive cases which were voluntarily reported within the National Enterovirus surveillance (EVSurv, based on investigation of patients with suspected aseptic meningitis/encephalitis and/or acute flaccid paralysis) by physicians within this period of time. Among these 72 patients, 38 (52.8%) were enterovirus positive and typed as echovirus (18 pediatric and 20 adult cases, median age 18.5 years; echovirus 18 (1), echovirus 2 (1), echovirus 30 (31), echovirus 33 (1), echovirus 9 (4)). At the same time, 45 aseptic meningitis cases in our cohort were excluded to be due to enteroviral infection (EV-negative). Three EV-negative patients were tested positive for varicella zoster virus (VZV) and 1 EV-negative patient for herpes simplex virus 2. Hospitalization was significantly longer in EV-negative cases. Cerebrospinal fluid analysis did not reveal significant differences between the two groups. After discharge, EV-meningitis resulted in significant burden of sick leave in our pediatric cohort as parents had to care for the children at home. Conclusions Voluntary syndromic surveillance, such as provided by the EVSurv in our study may be a valuable tool for epidemiological research. Our analyses suggest that EV-positive meningitis predominantly affects younger patients and may be associated with a rather benign clinical course, compared to EV-negative cases.

scholarly journals Use of port-a-cath in cancer patients: a single-center experience

2014 ◽  
Vol 8 (11) ◽  
pp. 1476-1482 ◽  
Author(s):  
Philomena Charlotte D’Souza ◽  
Shiyam Kumar ◽  
Annupam Kakaria ◽  
Rashid Al-Sukaiti ◽  
Khawaja Farhan Zahid ◽  
...  
Keyword(s):  
Cancer Patients ◽  
Cox Regression ◽  
Infectious Complications ◽  
University Hospital ◽  
Factors Affecting ◽  
Cox Regression Analysis ◽  
Sultan Qaboos University ◽  
Single Center Experience ◽  
One Year ◽  
The Right

Introduction: Central venous catheters play an important role in the management of cancer patients. Different types of devices are associated with different patterns of complications. We report on the pattern of use and rate of complications of port-a-caths in patients diagnosed with malignant cancer at a single institution. Methodology: The data were collected retrospectively from patients who received the treatment for solid tumors or lymphoma through a port-a-cath at the Sultan Qaboos University Hospital (SQUH) between January 2007 and February 2013. Results: A total of 117 port-a-caths were inserted in 106 patients. The majority (86; 73.5%) were implanted by an interventional radiologist, and the right internal jugular vein was accessed in 79 (67.5%) patients. Mean catheter indwelling time was 354 (range 3–1,876) days for all patients, 252 (3–1,876) and 389 days (13–1,139) for patients with and without complications, respectively. Thirty (25.6%) port-a-caths were removed prematurely, mainly due to infectious complications, while 17 (14.5%) were removed after completion of treatment. Staphylococcus aureus was the most frequently isolated organism, found in 8 (6.8%) patients. Underlying diagnosis (p < 0.001), chemotherapy regimen (p < 0.001), sensitivity to antibiotics (p = 0.01), and any complication (p < 0.001) were significant factors affecting the duration of port-a-cath use. None of these factors were significant on multivariate cox regression analysis. Conclusions: The mean duration of port-a-cath use was almost one year. Infection was the most common complication leading to premature removal, followed by port thrombosis.

scholarly journals Automation of the Clinical Laboratories with a D.N.A. Computer System

1972 ◽  
Vol 9 (1-6) ◽  
pp. 191-193
Author(s):  
R. A. Côté
Keyword(s):  
Computer System ◽  
University Hospital ◽  
Clinical Laboratories ◽  
One Year ◽  
The University

The clinical laboratories of the University Hospital at Sherbrooke have been computerised with a small dedicated system. The D.N.A. System is described generally and then more specifically as installed at Sherbrooke and is critically evaluated after one year of operation.

scholarly journals Bacterial Pathogens and Evaluation of a Cut-Off for Defining Early and Late Neonatal Infection

Antibiotics ◽  
2021 ◽  
Vol 10 (3) ◽  
pp. 278
Author(s):  
Pavla Kucova ◽  
Lumir Kantor ◽  
Katerina Fiserova ◽  
Jakub Lasak ◽  
Magdalena Röderova ◽  
...  
Keyword(s):  
Risk Factors ◽  
Bacterial Infections ◽  
Late Onset ◽  
Bacterial Pathogens ◽  
Neonatal Infection ◽  
University Hospital ◽  
Neonatal Infections ◽  
Mortality And Morbidity ◽  
Amoxicillin Clavulanic Acid ◽  
The University

Bacterial infections are an important cause of mortality and morbidity in newborns. The main risk factors include low birth weight and prematurity. The study identified the most common bacterial pathogens causing neonatal infections including their resistance to antibiotics in the Neonatal Department of the University Hospital Olomouc. Additionally, the cut-off for distinguishing early- from late-onset neonatal infections was assessed. The results of this study show that a cut-off value of 72 h after birth is more suitable. Only in case of early-onset infections arising within 72 h of birth, initial antibiotic therapy based on gentamicin with ampicillin or amoxicillin/clavulanic acid may be recommended. It has been established that with the 72-h cut-off, late-onset infections caused by bacteria more resistant to antibiotics may be detected more frequently, a finding that is absolutely crucial for antibiotic treatment strategy.

scholarly journals Meningitis gone viral: Description of the Echovirus Wave 2013 in Germany

2019 ◽  
Author(s):  
Jonas Graf ◽  
Christian Hartmann ◽  
Helmar C Lehmann ◽  
Carolin Otto ◽  
Ortwin Adams ◽  
...  
Keyword(s):  
Aseptic Meningitis ◽  
University Hospital ◽  
Enteroviral Infection ◽  
Echovirus 30 ◽  
Varicella Zoster ◽  
Fluid Analysis ◽  
Significant Burden ◽  
Simplex Virus ◽  
Herpes Simplex Virus 2 ◽  
The University

Abstract BACKGROUND: Aseptic meningitis epidemics may pose various health care challenges. METHODS: We describe the German enterovirus meningitis epidemics in the university hospital centers of Düsseldorf, Cologne and Berlin between January 1st and December 31st, 2013 in order to scrutinize clinical differences from other aseptic meningitis cases.RESULTS: A total of 72 enterovirus (EV-positive) meningitis cases were detected in our multicenter cohort, corresponding to 5.8% of all EV-positive cases which were voluntarily reported within the National Enterovirus surveillance (EVSurv, based on investigation of patients with suspected aseptic meningitis/encephalitis and/or acute flaccid paralysis) by physicians within this period of time. Among these 72 patients, 38 (52.8%) were enterovirus positive and typed as echovirus (18 pediatric and 20 adult cases, median age 18.5 years; echovirus 18 (1), echovirus 2 (1), echovirus 30 (31), echovirus 33 (1), echovirus 9 (4)). At the same time, 45 aseptic meningitis cases in our cohort were excluded to be due to enteroviral infection (EV-negative). Three EV-negative patients were tested positive for varicella zoster virus (VZV) and one EV-negative patient for herpes simplex virus 2. Hospitalization was significantly longer in EV-negative cases. Cerebrospinal fluid analysis did not reveal significant differences between the two groups. After discharge, EV-meningitis resulted in significant burden of sick leave in our pediatric cohort as parents had to care for the children at home. CONCLUSIONS: Voluntary syndromic surveillance, such as provided by the EVSurv in our study may be a valuable tool for epidemiological research. Our analyses suggest that EV-positive meningitis predominantly affects younger patients and may be associated with a rather benign clinical course, compared to EV-negative cases.

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