scholarly journals Antibiotic Sensitivity and Resistance Among the Most Common Uropathogens in Kidney Transplant Recipients

2015 ◽  
Vol 12 (1) ◽  
pp. 27-32
Author(s):  
Borelli Zlatkov ◽  
Jean Filipov ◽  
Emil Paskalev ◽  
Boyka Markova ◽  
Yuliya Marteva-Proevska ◽  
...  
Keyword(s):  
Antibiotic Resistance ◽  
Kidney Transplant ◽  
Antibiotic Sensitivity ◽  
High Sensitivity ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Bacterial Strains ◽  
Gram Positive ◽  
Transplant Center ◽  
Enterococcus Spp

Abstract Introduction. Urinary tract infection (UTI) among kidney transplant recipients (KTRs) is one of the most common complications after transplantation. The aim of our study was to analyze the antibiotic sensitivity and resistance of the most common agents causing UTI in Bulgarian KTRs followed up in our Transplant Center. Methods. We analyzed the antibiotic resistance and sensitivity of the most common strains of bacteria causing UTI in the Bulgarian KTRs, namely class Enterobac-teriaceae and Enterococcus spp. We used conventional biochemical methods to identify different strains of uro-pathogens-miniApi (bioMerieux, France) and BBL Crystal (BD). The antibiotic sensitivity was determined via disc-diffusing method, according to the accepted Bulgarian CLSI standard. We used WHONET, version 5.6 to analyze the antibiotic resistance data. Results. The total number of tested patients was 366 [males 228, females 138]. The total number of tested urine samples was 829 [positive ones-203), negative samples 606, contaminated 20]. The most commonly detected uropathogens in Bulgarian KTRs were Gram /-/ negative bacteria (63.80%). Of these, 93.28% belonged to the Enterobacteriaceae group, with E. coli, K. pneumoniae and the PPM /Proteus, Providentia, Mor-ganela/subgroup being the most common (54.5%, 19.20% and 16%, respectively). Gram /+/ positive bacteria were detected in 28.09% of the patients, Enterococcus spp being the most commonly isola-ted-67.79%. In the Enterococcus group, the strains of E. faecalis and E. faecium were the most commonly detected. The bacteria belonging to Enterobacteriaceae group were most sensitive to carbapenems and aminoglycosides, with sensitivity peaking to almost 100%, whereas they were least sensitive to aminopenicillines [sensitivity below 20%]. The PPM subgroup revealed very high sensitivity to beta-lactamase protected broad spectrum penicillins (Piperacillin/Tazobactam, sensitivity - 90%). Gram /+/ positive uropathogens were mostly sensitive to Linezolid, Vancomycin, Teicoplanin (100%). These strains were least sensitive to Erythromycin and Tetracicline (17.50%). Conclusions. Our results were similar to previous studies. The differences detected can be explained with the characteristics of the bacterial strains and the specific practice of each transplant center. Having in mind the possible complications of UTIs, further studies are needed to clarify the problem with antimicrobial resistance in uropathogens and the use of antibiotics after KT.

Readmission Rates Are a Poor Proxy for Transplant Center Quality of Care among US Kidney Transplant Recipients

2012 ◽  
Vol 94 (10S) ◽  
pp. 185 ◽  
Author(s):  
T. R. Srinivas ◽  
R. Woodward ◽  
A. Tang ◽  
D. Goldfarb ◽  
S. Flechner ◽  
...  
Keyword(s):  
Quality Of Care ◽  
Kidney Transplant ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Readmission Rates ◽  
Transplant Center

COVID-19 Infection in Kidney Transplant Recipients in Italy: Management Issues in a Kidney Transplant Center

2021 ◽  
Vol 19 (3) ◽  
pp. 284-286
Author(s):  
Gerardo Sarno ◽  
Enrico Russo ◽  
Aristide Ferrara ◽  
Vincenzo Cerbone ◽  
Rachele Villa
Keyword(s):  
Kidney Transplant ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Transplant Center ◽  
Management Issues

High-Sensitivity Troponin T Levels in Kidney Transplant Recipients

2012 ◽  
Vol 44 (9) ◽  
pp. 2545-2547 ◽  
Author(s):  
D. Arroyo ◽  
B. Quiroga ◽  
N. Panizo ◽  
M. Rodríguez-Ferrero ◽  
N. Macías ◽  
...  
Keyword(s):  
Kidney Transplant ◽  
Troponin T ◽  
High Sensitivity ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
High Sensitivity Troponin ◽  
High Sensitivity Troponin T

scholarly journals Impact of Navigators on First Visit to a Transplant Center, Waitlisting, and Kidney Transplantation

2018 ◽  
Vol 13 (10) ◽  
pp. 1550-1555 ◽  
Author(s):  
Catherine M. Sullivan ◽  
Kitty V. Barnswell ◽  
Kate Greenway ◽  
Cindy M. Kamps ◽  
Derrick Wilson ◽  
...  
Keyword(s):  
Confidence Interval ◽  
Kidney Transplant ◽  
Living Donor ◽  
Waiting List ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Transplant Center ◽  
And Control ◽  
Trial Intervention ◽  
Donor Transplant

Background and objectivesMany patients with ESKD face barriers in completing the steps required to obtain a transplant. These eight sequential steps are medical suitability, interest in transplant, referral to a transplant center, first visit to center, transplant workup, successful candidate, waiting list or identify living donor, and receive transplant. This study sought to determine the effect of navigators on helping patients complete these steps.Design, setting, participants, & measurementsOur study was a cluster randomized, controlled trial involving 40 hemodialysis facilities and four transplant centers in Ohio, Kentucky, and Indiana from January 1, 2014 to December 31, 2016. Four trained kidney transplant recipients met regularly with patients on hemodialysis at 20 intervention facilities, determined their step in the transplant process, and provided tailored information and assistance in completing that step and subsequent steps. Patients at 20 control facilities continued to receive usual care. Primary study outcomes were waiting list placement and receipt of a deceased or living donor transplant. An exploratory outcome was first visit to a transplant center.ResultsBefore the trial, intervention (1041 patients) and control (836 patients) groups were similar in the proportions of patients who made a first visit to a transplant center, were placed on a waiting list, and received a deceased or living donor transplant. At the end of the trial, intervention and control groups were also similar in first visit (16.1% versus 13.8%; difference, 2.3%; 95% confidence interval, −0.8% to 5.5%), waitlisting (16.3% versus 13.8%; difference, 2.5%; 95% confidence interval, −1.2% to 6.1%), deceased donor transplantation (2.8% versus 2.2%; difference, 0.6%; 95% confidence interval, −0.8% to 2.1%), and living donor transplantation (1.2% versus 1.0%; difference, 0.1%; 95% confidence interval, −0.9% to 1.1%).ConclusionsUse of trained kidney transplant recipients as navigators did not increase first visits to a transplant center, waiting list placement, and receipt of deceased or living donor transplants.

MO999COMPARISON OF BASILIXIMAB VS NO INDUCTION ON 12-MONTHS RENAL FUNCTION IN KIDNEY TRANSPLANT RECIPIENTS IN THE TACROLIMUS ERA

2021 ◽  
Vol 36 (Supplement_1) ◽  
Author(s):  
Zdenek Lys ◽  
Ivo Valkovsky ◽  
Pavel Havranek ◽  
Jarmila Dedochova ◽  
Jana Polaskova ◽  
...  
Keyword(s):  
Renal Function ◽  
Kidney Transplantation ◽  
Serum Creatinine ◽  
Kidney Transplant ◽  
Interleukin 2 ◽  
Graft Function ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Median Serum ◽  
Transplant Center

Abstract Background and Aims IL2-RA (Interleukin 2 receptor antagonist) are recommended for the induction immunosuppression of kidney transplant recipients in patients with low/standard immunological risk. Studies showing the effectiveness of these substances have often been performed in patients taking cyclosporine. We aimed to find out whether the same results would be obtained with the more effective tacrolimus in an immunosuppressive regimen. Method Induction immunosuppression using IL2-RA basiliximab in all patients undergoing kidney transplantation has been routinely used in our transplant center since April 1, 2018. We retrospectively compared outcomes of kidney transplantation of the last 40 patients before introduction of induction and the first 40 patients after the induction (monitored period of analysis is June 2017 to January 2019). All patients in each group received baseline immunosuppression of tacrolimus, corticosteroid and mycophenolate. We selected patients with low immunological risk (1st transplant, panel reactive antibodies up to 20%, without donor specific antibodies, donation after brain death) in both groups and evaluated their renal outcomes (serum creatinine and estimated glomerular filtration rate/eGFR) at 12 months after transplantation. Results Patients in the groups withnout and with basiliximab induction were of comparable age (51.9 years vs. 54.7) and with similar retransplantation rate (20%). The 1-year survival of patients and kidneys was the same (97.4% patient survival and 92.1% renal survival). Renal transplant function at 12 months was analyzed in 21 patients without and 19 patients with basiliximab induction with low baseline immunological risk. The patients who received basiliximab inductive immunosuppression had better graft function 12 months compared to patients without basiliximab administration: median serum creatinine level 112 µmol/L vs. 127 µmol/L (P=0.047) and eGFR 0.85 ml/s vs. 0.77 ml/s (P=0.347). Better renal function was also shown in the subgroup of patients older than 65 years. Conclusion At our transplant center, the introduction of basiliximab induction in patients at low immunological risk led to improved graft function in the short term despite the growing subpopulation of geriatric patients.

scholarly journals Outcomes for Somali immigrant kidney transplant recipients in a large-volume transplant center

2020 ◽  
Vol 5 (4) ◽  
pp. 100066
Author(s):  
Kent J. Peterson ◽  
Oscar K. Serrano ◽  
Marjorie Odegard ◽  
Steven J. Mongin ◽  
Danielle Berglund ◽  
...  
Keyword(s):  
Kidney Transplant ◽  
Large Volume ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Transplant Center ◽  
Somali Immigrant
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