In situ methanolic solvent synthesis, spectroscopic and thermogravimetric characterizations of three new transition metal complexes of trimethoprim drug

Abstract Trimethoprim drug (TMP) complexes of copper (II), cobalt (II), and nickel (II) were prepared and discussed by using elemental analysis (C, H, N analysis), magnetic, molar conductance, FTIR, Raman spectroscopy, electron spin resonance (ESR) and UV-vis spectroscopy analyses. TMP drug coordinated as a tridentate ligand towards the respected three metal ions through two nitrogen atoms of amino groups and nitrogen atom of pyrimidine ring which flanked between –NH2 groups, these assignments confirmed by spectroscopic, magnetic, ESR and thermogravimetric analyses with formulas [Cu(TMP)(H2O)3]Cl2, [Co(TMP)(H2O)3]Cl2 and [Ni(TMP) (H2O)]Cl2. Copper (II) and cobalt (II) complexes have an octahedral geometrical structure included one TMP molecule, three coordinated water molecules and two uncoordinated chlorine atoms while, nickel(II)–TMP complex has a tetrahedral geometric configuration that involved one TMP molecule, one coordinated water molecule and two uncoordinated chlorine atoms. The activation energies and other kinetic thermodynamic parameters were estimated based on the employed of the Coats-Redfern and Horowitz-Metzger equations. The nano–structured form of the synthesized TMP complexes was confirmed dependent on the transmission electron microscopy (TEM).

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Synthesis, spectroscopic and thermogravimetric interpretations of UO2(II), ZrO(II), Zr(IV), VO(II) and V(V) ciprofloxacin antibiotic drug complexes

Polish Journal of Chemical Technology ◽

10.2478/pjct-2021-0007 ◽

2021 ◽

Vol 0 (0) ◽

Author(s):

Lamia A. Albedair

Keyword(s):

Metal Ion ◽

Thermal Studies ◽

Analysis Data ◽

Molar Conductance ◽

Water Molecules ◽

Transmission Electron ◽

Antibiotic Drug ◽

Electrolytic Properties ◽

Diamagnetic Behavior ◽

Coordinated Water

Abstract New five ciprofloxacin (CIP) complexes of dioxouranium(II), oxozirconium(II), zirconium(IV), oxovanadium(II) and vanadium(IV) in the proportion 1:2 have been prepared using CIP as a drug chelate with UO2(NO3)2. 6H2O, ZrOCl2. 8H2O, ZrCl4, VOSO4. xH2O and V2O5 respectively. The CIP complexes have been characterized based on the elemental analysis, molar conductance, magnetic, (FTIR & 1HNMR) spectral and thermal studies. The molar conductance studies of the synthesized complexes in DMSO solvent with concentration of 10–3 M indicate their non-electrolytic properties. At room temperature, the magnetic moment measurements revealed a diamagnetic behavior for all CIP prepared complexes. The different formulas of the new complexes can be represented as [UO2(CIP)2(NO3)2] (I), [VO(CIP)2(SO4)(H2O)] (II), [V2(O)(O2)2(CIP)2] (III), [Zr(O)(CIP)2(Cl)2] (IV), and [Zr(CIP)2(Cl)4] (V). The thermal analysis data of the complexes indicates the absence of coordinated water molecules except for vanadyl(II) complex (II). The CIP chelate is a uni-dentate ligand coordinated to the mentioned metal ion through terminal piperazinyl nitrogen. The transmission electron microscopy (TEM) investigation confirms the nano-structured form of the complexes.

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On the selective aerobic oxidation of benzyl alcohol with Pd/Au-nanoparticles in batch and flow

Nanotechnology Reviews ◽

10.1515/ntrev-2012-0085 ◽

2014 ◽

Vol 3 (1) ◽

pp. 99-110 ◽

Cited By ~ 2

Author(s):

Hannes Alex ◽

Norbert Steinfeldt ◽

Klaus Jähnisch ◽

Matthias Bauer ◽

Sandra Hübner

Keyword(s):

Catalytic Activity ◽

Benzyl Alcohol ◽

Aerobic Oxidation ◽

X Ray ◽

X Ray Scattering ◽

Oxidation Of Benzyl Alcohol ◽

Transmission Electron ◽

Vis Spectroscopy ◽

Selective Aerobic Oxidation

AbstractNanoparticles (NP) have specific catalytic properties, which are influenced by parameters like their size, shape, or composition. Bimetallic NPs, composed of two metal elements can show an improved catalytic activity compared to the monometallic NPs. We, herein, report on the selective aerobic oxidation of benzyl alcohol catalyzed by unsupported Pd/Au and Pd NPs at atmospheric pressure. NPs of varying compositions were synthesized and characterized by UV/Vis spectroscopy, transmission electron microscopy (TEM), and small-angle X-ray scattering (SAXS). The NPs were tested in the model reaction regarding their catalytic activity, stability, and recyclability in batch and continuous procedure. Additionally, in situ extended X-ray absorption fine structure (EXAFS) measurements were performed in order to get insight in the process during NP catalysis.

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Synthesis, Single Crystal Structural Investigation, Hirshfeld Surface Analysis, Thermoanalysis and Spectroscopic Study of Two New Cu(II) and Co(II) Transition-Metal Complexes

Crystals ◽

10.3390/cryst11080986 ◽

2021 ◽

Vol 11 (8) ◽

pp. 986

Author(s):

Rim Boubakri ◽

Mirosław Szybowicz ◽

Mariola Sadej ◽

Sarra Soudani ◽

Frédéric Lefebvre ◽

...

Keyword(s):

Hydrogen Bonds ◽

Single Crystal ◽

Organic Ligand ◽

Free Water ◽

Pyrimidine Ring ◽

Water Molecules ◽

Absorption Bands ◽

Infrared And Raman Spectroscopy ◽

Homo And Lumo ◽

Coordinated Water

Two new complexes, [Cu(dimpyr)2(H2O)2](NO3)2.2H2O (1) and (Hamdimpy)2[CoCl4].H2O (2), with the monodentate ligand 2-amino-6-methylpyrimidin-4-(1H)-one (dimpyr) and the countercation 4-amino-2,6-dimetylpyrimidium (Hamdimpy), respectively, were prepared and characterized by single crystal X-ray diffraction, elemental analysis and IR spectroscopy. In (1), the Cu(II) cation is tetracoordinated, in a square plan fashion, by two nitrogen atoms from the pyrimidine ring of the organic ligand and two oxygen atoms of two coordinated water molecules. In the atomic arrangement, the CuO2N2 square planes are interconnected via the formation of O-H…O hydrogen bonds involving both coordinated and free water molecules and NO3− nitrate anions to form inorganic layers parallel to the (a, b) plane at z = (2n + 1)/4. In (2), the central atom Co(II) is four-coordinated in a distorted tetrahedral fashion by four Cl− ions. The [CoCl4]2− tetrahedra are arranged parallel to the plane (110) at x = (2n + 1)/2 and the organic cations are grafted between them by establishing with them hydrogen bonds of CH…Cl and NH…Cl types. The vibrational absorption bands were identified by infrared and Raman spectroscopy. Intermolecular interactions were investigated via Hirshfeld surfaces and electronic properties such as HOMO and LUMO energies were derived. The two compounds were characterized by thermal analysis to determine their thermal behavior with respect to temperature.

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Photocatalytic Degradation of Methylene Blue under UV Light Irradiation on Prepared CarbonaceousTiO2

The Scientific World JOURNAL ◽

10.1155/2014/415136 ◽

2014 ◽

Vol 2014 ◽

pp. 1-8 ◽

Cited By ~ 18

Author(s):

Zatil Amali Che Ramli ◽

Nilofar Asim ◽

Wan N. R. W. Isahak ◽

Zeynab Emdadi ◽

Norasikin Ahmad-Ludin ◽

...

Keyword(s):

Methylene Blue ◽

Activated Carbon ◽

In Situ Polymerization ◽

Uv Light ◽

Carbon Composite ◽

Light Irradiation ◽

Uv Light Irradiation ◽

Transmission Electron ◽

Vis Spectroscopy

This study involves the investigation of altering the photocatalytic activity of TiO2using composite materials. Three different forms of modified TiO2, namely, TiO2/activated carbon (AC), TiO2/carbon (C), and TiO2/PANi, were compared. The TiO2/carbon composite was obtained by pyrolysis of TiO2/PANi prepared by in situ polymerization method, while the TiO2/activated carbon (TiO2/AC) was obtained after treating TiO2/carbon with 1.0 M KOH solution, followed by calcination at a temperature of 450°C. X-ray powder diffraction (XRD), transmission electron microscopy (TEM), Fourier transform infrared (FTIR), thermogravimetric analysis (TG-DTA), Brunauer-Emmet-Teller (BET), and UV-Vis spectroscopy were used to characterize and evaluate the prepared samples. The specific surface area was determined to be in the following order: TiO2/AC > TiO2/C > TiO2/PANi > TiO2(179 > 134 > 54 > 9 m2 g−1). The evaluation of photocatalytic performance for the degradation of methylene blue under UV light irradiation was also of the same order, with 98 > 84.7 > 69% conversion rate, which is likely to be attributed to the porosity and synergistic effect in the prepared samples.

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Synthesis, Characterization of La(III), Nd(III), and Er(III) Complexes with Schiff Bases Derived from Benzopyran-4-one and Thier Fluorescence Study

International Journal of Inorganic Chemistry ◽

10.1155/2012/901415 ◽

2012 ◽

Vol 2012 ◽

pp. 1-13 ◽

Cited By ~ 12

Author(s):

Aida L. El-Ansary ◽

Nora S. Abdel-Kader

Keyword(s):

Schiff Bases ◽

Molar Conductance ◽

Spectral Studies ◽

Water Molecules ◽

Stoichiometric Ratio ◽

Binuclear Complexes ◽

Fluorescence Study ◽

H Nmr ◽

Coordinated Water

The Schiff bases, L1, L2, and L3, are synthesized from the condensation of 5,7-dihydroxy-6-formyl-2-methylbenzopyran-4-one (L) with 2-aminopyridine (1), p-phenylenediamine (2), and o-phenylenediamine (3). The prepared Schiff bases react with lanthanum (III), neodymium (III), and erbium (III) nitrate to give complexes with stoichiometric ratio (1 : 1) (ligand : metal). The binuclear complexes of Er(III) with L3 and the three metal ions with L2 are separated. The complexes have been characterized by elemental analysis, molar conductance, electronic absorption, and infrared, 1H-NMR spectral studies. The presence of hydrated and coordinated water molecules is inferred from thermogravimetric analysis. Thermal degradation studies show that the final product is the metal oxide. The luminescence properties of the Nd(III) and Er(III) complexes in dimethylformamide (DMF) solutions were investigated.

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Antimicrobial Study of Newly Synthesized Lanthanide(III) Complexes of 2-[2-hydroxy-3-methoxyphenyl]-3-[2-hydroxy-3-methoxybenzylamino]-1,2-dihydroquinazolin-4(3H)-one

Metal-Based Drugs ◽

10.1155/2007/37348 ◽

2007 ◽

Vol 2007 ◽

pp. 1-7 ◽

Cited By ~ 17

Author(s):

Kalagouda B. Gudasi ◽

Vidyadhar C. Havanur ◽

Siddappa A. Patil ◽

Basavaraj R. Patil

Keyword(s):

Thermal Studies ◽

Carbonyl Oxygen ◽

Molar Conductance ◽

Tridentate Ligand ◽

Amine Nitrogen ◽

Antibacterial And Antifungal Activities ◽

Phenolic Oxygen ◽

Coordinated Water ◽

Dta Studies ◽

Antibacterial And Antifungal

New lanthanide(III) complexes with 2-[2-hydroxy-3-methoxyphenyl]-3-[hydroxyl-3-methoxybenzylamino]-1,2-dihydroquin-azoline-4(3H)-one (Hmpbaq) have been synthesized and characterized by elemental analysis, conductance measurements, magnetic susceptibilities, spectroscopic (IR, NMR, UV, EPR), and thermal studies. Molar conductance studies indicate 1 : 1 electrolytic behavior for these complexes. IR spectra indicate that Hmpbaq acts as a tridentate ligand coordinating through carbonyl oxygen, benzyl amine nitrogen, and deprotonated phenolic oxygen. TG and DTA studies of La(III) and Pr(III) complexes indicate the presence of two coordinated water molecules. Based on these studies, the complexes have been formulated as [La(mpbaq)2(H2O)2]·NO3, where Ln = La(III), Pr(III), Nd(III), Sm(III), Eu(III), Gd(III), Th(III), Dy(III), and Y(III). The ligand, lanthanide(III) salts, and the corresponding complexes have been simultaneously screened for their antibacterial and antifungal activities and compared with the drugs in use.

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In situ variable-temperature single crystal X-ray diffraction studies of the single-crystal-to-single-crystal dehydration and rehydration of a mixed-ligand 2D zinc metal–organic framework using trimesate and 4,4′-bipyridine-N,N′-dioxide as ligands

CrystEngComm ◽

10.1039/c5ce01297j ◽

2015 ◽

Vol 17 (46) ◽

pp. 8946-8956 ◽

Cited By ~ 7

Author(s):

Tayyibah Tahier ◽

Clive L. Oliver

Keyword(s):

Single Crystal ◽

Variable Temperature ◽

Metal Organic Framework ◽

Mixed Ligand ◽

Water Molecules ◽

X Ray Diffraction ◽

Metal Organic ◽

Reversible Loss ◽

Coordinated Water

A mixed-ligand 2D MOF based on ZnSO4, trimesate and 4,4′-bipyridine-N,N′-dioxide shows reversible loss of uncoordinated and coordinated water molecules.

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In-Situ Copper(II) Complexes of Some Quinolone Drug Ligands Were Discussed for Their Molecular Structures: Synthesis in Binary Solvent

Journal of Computational and Theoretical Nanoscience ◽

10.1166/jctn.2017.6363 ◽

2017 ◽

Vol 14 (1) ◽

pp. 561-576 ◽

Cited By ~ 1

Author(s):

Samy M El-Megharbel ◽

M. A Hussien ◽

Moamen S Refat

Keyword(s):

Magnetic Moments ◽

Esr Spectra ◽

Molecular Structures ◽

Water Molecules ◽

Binary Solvent ◽

Carboxylate Groups ◽

Conductance Data ◽

Spin Resonance ◽

Ft Ir

A series of copper solid complexes with different generation of quinolone drugs of the type [Cu(L)n(Cl)x(H2O)y]·zH2O ((1) L: nalidixic acid (Nal), n = 2, x = 2, y = 2, z = 9; (2) L: oxolonic acid (Oxo), n = 2, x = 2, y = 2, z = 2; (3) L: pipemidic acid (Pip), n = 2, x = 2, y = 2, z = 4; (4) L: lomefloxacin (Lom), n = 2, x = 2, y = 2, z = 2; (5) L: pefloxacin mesylate (Pef), n = 2, x = 2, y = 2, z 2; (6) L: levofloxacin (Lev), n = 2, x = 2, y = 2, z = 2) were synthesized and identified using micro-analytical, FT-IR spectroscopy, conductance data, effective magnetic moments, electronic UV-vis spectra, electron-spin-resonance (ESR) spectra. Except levofloxacin that behaves as bi-dentate fashion through oxygen atoms of pyridone and carboxylate groups, the other quinolone drug chelates acts as uni-dentate via nitrogen atom of pyridone/piperazyl moiety. Electronic spectroscopic tools are in agreement with an octahedral geometrical structure. Thermal degradation analyses TG-DTG in nitrogen gas environmental are discussed the number and location of water molecules. The thermal decomposition process is completely in 3–5 steps, that the first step is responsible to loss of uncoordinated water molecules. The stabilities of Cu(II) complex 1–5 were studied dependent on activations of energy E*, entropy ΔS*, enthalpy ΔH* and Gibbs free energy ΔG* that have been estimated using Coats-Redfern and Horowitz-Metzeger non-isothermal methods. Molecular docking was used to predict the binding between some quinolone drugs with the receptor of breast cancer mutant 3hb5-oxidoreductase.

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New Insights into the Chemistry of Oxovanadium(IV) Complexes with N4 Coordinating Ligands

ISRN Inorganic Chemistry ◽

10.1155/2013/871640 ◽

2013 ◽

Vol 2013 ◽

pp. 1-5 ◽

Cited By ~ 1

Author(s):

Ashok Kumar Yadava ◽

Hardeo Singh Yadav ◽

Uma Shanker Yadav ◽

Devendra Pratap Rao

Keyword(s):

Chelating Agents ◽

Magnetic Moments ◽

Molar Conductance ◽

In Situ Method ◽

Vanadyl Ion ◽

Spin Resonance ◽

Elemental Analyses ◽

Resonance Data ◽

Electron Spin Resonance Data

The syntheses of new oxovanadium(IV) complexes having general formula [VO(mac)]SO4 have been carried out by using in situ method of preparation where vanadyl ion acts as kinetic template for the ligands derived by condensation of 2,2′-pyridil with 1,2-diaminopropane and 1,3-diaminopropane. The complexes were characterized by elemental analyses, molar conductance, magnetic moments, and spectral (infrared, electronic, and electron spin resonance) data. All the oxovanadium(IV) complexes are five coordinate wherein derived ligands act as tetradentate chelating agents.

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An Asymmetric Salen-type Bisoxime Ligand and Its Supramolecular Copper(II) Complex: Synthesis, Crystal Structure and Spectral Properties

Zeitschrift für Naturforschung B ◽

10.1515/znb-2012-0303 ◽

2012 ◽

Vol 67 (3) ◽

pp. 197-203 ◽

Cited By ~ 2

Author(s):

Wen-Kui Dong ◽

Yin-Xia Sun ◽

Si-Jia Xing ◽

Yuan Wang ◽

Xiong-Hou Gao

Keyword(s):

Crystal Structure ◽

Molar Conductance ◽

Stacking Interactions ◽

X Ray Diffraction ◽

X Ray ◽

Pyramidal Geometry ◽

Vis Spectroscopy ◽

Dta Analysis ◽

Coordinated Water ◽

Square Pyramidal Geometry

A supramolecular Cu(II) complex [CuL(H2O)] with an asymmetric salen-type bisoxime ligand (H2L = 4-nitro-6ʹ-methoxy-2,2ʹ-[ethylenediyldioxybis(nitrilomethylidyne)]diphenol) has been synthesized and characterized by elemental analysis, IR and UV/Vis spectroscopy, TG-DTA analysis, and molar conductance measurements. The crystal structure of the Cu(II) complex has been determined by single-crystal X-ray diffraction. The Cu(II) atom is penta-coodinated by N2O2 donor atoms from the asymmetic salen-type bisoxime L2− unit and one oxygen atom from the coordinated water molecule, resulting in an almost regular square-pyramidal geometry. With the help of intermolecular O-H· · ·O, C-H· · ·O hydrogen bonding and π · · ·π stacking interactions, a self-assembled 3D supramolecular structure is formed.

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