Green synthesis of thioxoimidazolidine derivative ligand: Spectroscopic, thermal and biological assignments of new Cu(II), Co(II), and Ni(II) chelates in neutral system

Abstract Eco-friendly synthesis of ethyl 3-(4-oxo-3-(1-(pyridin-3-yl)ethylideneamino)-2-thioxoimidazolidin-1-yl)propanoate (4) ligand (L) using microwave irradiation technique was described. The structure of thioxoimidazolidine derivative ligand compound has been established based on different types of analyses such as infrared, 1H-NMR, 13C-NMR, and mass spectra as well as elemental analysis. The copper, cobalt, and nickel(II) complexes with molecular formula [M(L)(H2O)4]Cl2 (where M = Co(II), Ni(II), and Cu(II), L = thioxoimidazolidine derivative ligand), have been prepared and well-characterized using microanalytical, conductivity measurements, magnetic, spectroscopic, and physical analyses. Upon the outcome results of analyses, the stoichiometry of the synthesized complexes is 1:1 (M:L). The molar conductance values concluded that the behavior of metal complexes was electrolytes. The 3-(4-oxo-3-(1-(pyridin-3-yl)ethylideneamino)-2-thioxoimidazolidin-1-yl)propanoate chelate acts as a monovalent bidentate fashion via nitrogen and oxygen atoms of both thioxoimidazolidine and propanoate ester moieties. The geometric structures of the synthesized metal complexes are an octahedral configuration based on spectroscopic and magnetic moment studies. The thermogravimetric assignments deduced that the presence of four coordinated water molecules. The synthesized copper(II), cobalt(II), and nickel(II) complexes were biologically checked against G+ and G- bacteria and two species of fungi (Aspergillus Nigaer, and Penicillium Sp.).

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Synthesis, Characterization and Antimicrobial Studies of N1-[(1E)-1-(2-Hydroxyphenyl) ethylidene]-2-oxo-2H-chromene-3-carbohydrazide and its Metal Complexes

E-Journal of Chemistry ◽

10.1155/2009/416836 ◽

2009 ◽

Vol 6 (3) ◽

pp. 615-624 ◽

Cited By ~ 2

Author(s):

K. Siddappa ◽

K. Mallikarjun ◽

Tukaram Reddy ◽

M. Mallikarjun ◽

C. V. Reddy ◽

...

Keyword(s):

Antimicrobial Activity ◽

Magnetic Susceptibility ◽

Schiff Base ◽

Metal Complexes ◽

Molar Conductance ◽

Tetrahedral Geometry ◽

H Nmr ◽

Antimicrobial Studies ◽

Mononuclear Complexes ◽

Uv Visible

A new complexes of the type ML, MʹL and M″L [where M=Cu(II), Co(II), Ni(II) and Mn(II), Mʹ=Fe(III) and M″=Zn(II), Cd(II) and Hg(II) and L=N1-[(1E)-1-(2-hydroxyphenyl)ethylidene]-2-oxo-2H-chromene- 3-carbohydrazide (HL)] Schiff base have been synthesized and characterized by elemental analysis, magnetic susceptibility, molar conductance, IR,1H NMR, UV-Visible and ESR data. The studies indicate the HL acts as doubly monodentate bridge for metal ions and form mononuclear complexes. The complexes Ni(II), Co(II), Cu(II) Mn(II) and Fe(III) complexes are found to be octahedral, where as Zn(II), Cd(II) and Hg(II) complexes are four coordinated with tetrahedral geometry. The synthesized ligand and its metal complexes were screened for their antimicrobial activity.

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Synthesis, Characterization of La(III), Nd(III), and Er(III) Complexes with Schiff Bases Derived from Benzopyran-4-one and Thier Fluorescence Study

International Journal of Inorganic Chemistry ◽

10.1155/2012/901415 ◽

2012 ◽

Vol 2012 ◽

pp. 1-13 ◽

Cited By ~ 12

Author(s):

Aida L. El-Ansary ◽

Nora S. Abdel-Kader

Keyword(s):

Schiff Bases ◽

Molar Conductance ◽

Spectral Studies ◽

Water Molecules ◽

Stoichiometric Ratio ◽

Binuclear Complexes ◽

Fluorescence Study ◽

H Nmr ◽

Coordinated Water

The Schiff bases, L1, L2, and L3, are synthesized from the condensation of 5,7-dihydroxy-6-formyl-2-methylbenzopyran-4-one (L) with 2-aminopyridine (1), p-phenylenediamine (2), and o-phenylenediamine (3). The prepared Schiff bases react with lanthanum (III), neodymium (III), and erbium (III) nitrate to give complexes with stoichiometric ratio (1 : 1) (ligand : metal). The binuclear complexes of Er(III) with L3 and the three metal ions with L2 are separated. The complexes have been characterized by elemental analysis, molar conductance, electronic absorption, and infrared, 1H-NMR spectral studies. The presence of hydrated and coordinated water molecules is inferred from thermogravimetric analysis. Thermal degradation studies show that the final product is the metal oxide. The luminescence properties of the Nd(III) and Er(III) complexes in dimethylformamide (DMF) solutions were investigated.

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Spectral, Magnetic and Biological Studie on Some Bivalent 3d Metal Complexes of Hydrazine Derived Schiff-Base Ligands

Metal-Based Drugs ◽

10.1155/mbd.1997.65 ◽

1997 ◽

Vol 4 (2) ◽

pp. 65-68 ◽

Cited By ~ 5

Author(s):

Zahid H. Chohan ◽

Syed K. A. Sherazi

Keyword(s):

Schiff Base ◽

Metal Complexes ◽

Elemental Analysis ◽

Magnetic Moment ◽

Bacterial Species ◽

Biological Properties ◽

Molar Conductance ◽

Schiff Base Ligands ◽

H Nmr ◽

3D Metal Complexes

Metal(II) complexes of hydrazine derived Schiff-base ligands of the type M(L)2Cl2 where M = Co, Cu, Ni and Zn and L = L1 and L2 have been prepared and characterised by molar conductance, magnetic moment, elemental analysis and electronic, IR, H-NMR and C13 spectral data.The different modes of chelation of the ligands and their comparative biological properties against different bacterial species are reported.

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Antimicrobial Applications of Transition Metal Complexes of Benzothiazole Based Terpolymer: Synthesis, Characterization, and Effect on Bacterial and Fungal Strains

Bioinorganic Chemistry and Applications ◽

10.1155/2014/764085 ◽

2014 ◽

Vol 2014 ◽

pp. 1-16 ◽

Cited By ~ 10

Author(s):

Mohamed A. Riswan Ahamed ◽

Raja S. Azarudeen ◽

N. Mujafar Kani

Keyword(s):

Metal Complexes ◽

Elemental Analysis ◽

Biological Activities ◽

Gel Permeation Chromatography ◽

Spectral Studies ◽

X Ray Diffraction ◽

Spectral Techniques ◽

H Nmr ◽

Uv Visible ◽

C Nmr

Terpolymer of 2-amino-6-nitro-benzothiazole-ethylenediamine-formaldehyde (BEF) has been synthesized and characterized by elemental analysis and various spectral techniques like FTIR, UV-Visible, and1H and13C-NMR. The terpolymer metal complexes were prepared with Cu2+, Ni2+, and Zn2+metal ions using BEF terpolymer as a ligand. The complexes have been characterized by elemental analysis and IR, UV-Visible, ESR,1H-NMR, and13C-NMR spectral studies. Gel permeation chromatography was used to determine the molecular weight of the ligand. The surface features and crystalline behavior of the ligand and its complexes were analyzed by scanning electron microscope and X-ray diffraction methods. Thermogravimetric analysis was used to analyze the thermal stability of the ligand and its metal complexes. Kinetic parameters such as activation energy(Ea)and order of reaction (n) and thermodynamic parameters, namely,ΔS,ΔF,S*, andZ, were calculated using Freeman-Carroll (FC), Sharp-Wentworth (SW), and Phadnis-Deshpande (PD) methods. Thermal degradation model of the terpolymer and its metal complexes was also proposed using PD method. Biological activities of the ligand and its complexes were tested againstShigella sonnei,Escherichia coli,Klebsiellaspecies,Staphylococcus aureus,Bacillus subtilis, andSalmonella typhimuriumbacteria andAspergillus flavus,Aspergillus niger,Penicilliumspecies,Candida albicans,Cryptococcus neoformans,Mucor speciesfungi.

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Coordination Modes of a Schiff Base Derived from Substituted 2-Aminothiazole with Chromium(III), Manganese(II), Iron(II), Cobalt(II), Nickel(II) and Copper(II) Metal Ions: Synthesis, Spectroscopic and Antimicrobial Studies

E-Journal of Chemistry ◽

10.1155/2011/282061 ◽

2011 ◽

Vol 8 (4) ◽

pp. 1750-1764 ◽

Cited By ~ 4

Author(s):

Ambit Thakar ◽

Krishnakant Joshi ◽

Kishor Pandya ◽

Arvind Pancholi

Keyword(s):

Schiff Base ◽

Metal Ions ◽

Transition Metal Complexes ◽

Mass Spectra ◽

Antibacterial Activities ◽

Molar Conductance ◽

Spectral Techniques ◽

H Nmr ◽

Antimicrobial Studies ◽

C Nmr

Transition metal complexes of Cr(III), Mn(II), Fe(II), Co(II), Ni(II) and Cu(II) metal ions with general stoichiometry [ML2.2H2O] and [ML3], where M= Mn(II), Cr(III), Fe(II), Co(II), Ni(II) and Cu(II), L= Schiff base derived from the condensation of 2-amino-4(4’-phenyl/methylphenyl)-5-methyl-thiazole with 4-acetyl-1(3-chloro phenyl)-3-methyl-2-pyrazoline-5-ones, have been synthesized and structurally characterized by elemental analysis, molar conductance measurements, magnetic susceptibility measurements and spectral techniques like IR, UV,1H NMR,13C NMR and Mass Spectra. All the complexes were found to be octahedral geometry. The ligand and its complexes have been screened for their antifungal and antibacterial activities against three fungi,i.e. Alternaria brassicae, Aspergillus nigerandFesarium oxysporumand two bacteria,i.e. Xanthomonas compestrisandPseudomonas aeruginosa.

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Synthesis and Characterization of New Lead(II) and Organotin(IV) Complexes of Schiff Bases Derived from Histidine and Methionine

International Journal of Inorganic Chemistry ◽

10.1155/2012/568797 ◽

2012 ◽

Vol 2012 ◽

pp. 1-7 ◽

Cited By ~ 5

Author(s):

Har Lal Singh ◽

J. B. Singh

Keyword(s):

Schiff Base ◽

Metal Complexes ◽

Analytical Data ◽

Molar Conductance ◽

Molar Ratio ◽

Azomethine Nitrogen ◽

Spectral Studies ◽

Tetrahedral Geometry ◽

H Nmr ◽

Carboxylate Oxygen

New Schiff base (HL) ligand is prepared via condensation of isatins and amino acids in 1:1 molar ratio. Metal complexes are prepared and characterized by elemental analysis, molar conductance, electronic, infrared, and multinuclear magnetic resonance (1H NMR, 13C NMR, and 119Sn NMR). The analytical data showed that the ligand acts as bidentate toward metal ions via azomethine nitrogen and carboxylate oxygen by a stoichiometric reaction of metal : ligand (1 : 2) to from metal complexes (Pb(II)(L)2 and Bu2Sn(L)2, where L is the Schiff base ligands of histidine and methionine). The conductivity values between 15 and 25 Ω−1cm2 mol−1 in DMF imply the presence of nonelectrolyte species. On the basis of the above spectral studies, distorted octahedral and tetrahedral geometry have been proposed for the resulting organotin(IV) and lead(II) complexes.

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Transition Metal Complexes of Methyl-quinolino[3,2-b][1,5]benzodiazepine and Methylquinolino [3,2-b][1,5]benzoxazepine: Synthesis, Characterisation and Antimicrobial Studies

E-Journal of Chemistry ◽

10.1155/2007/836582 ◽

2007 ◽

Vol 4 (1) ◽

pp. 39-45

Author(s):

B. Basavaraju ◽

H. S. Bhojya Naik ◽

M. C. Prabhakara

Keyword(s):

Antifungal Activity ◽

Metal Complexes ◽

Transition Metal Complexes ◽

Molar Conductance ◽

Antibacterial And Antifungal Activity ◽

Magnetic Studies ◽

H Nmr ◽

Antimicrobial Studies ◽

Uv Visible ◽

Antibacterial And Antifungal

The synthesis and characterisation of title complexes of the ligand Methylquinolino[3,2-b][1,5]benzodiazepine (MQBD) and Methyl-quinolino[3,2-b][1,5]benzoxazepine (MQBO) are reported. The complexes have been characterized by elemental analysis, molar conductance, magnetic studies, IR,1H NMR and UV-visible studies. They have the stoichiometry [ML2Cl2] where M=Co(II)/Ni(II), L=MQBD/MQBO and [MLCl2] where M=Zn(II)/Cd(II), L=MQBD/MQBO. The antibacterial and antifungal activity of the metal complexes has been investigated.

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Synthesis, Characterization and Antibacterial Activity of Novel Schiff Bases Derived from 4-Phenyl-2-aminothiazole and their Mn(II), Fe(II), Co(II), Ni(II) and Cu(II) Metal complexes

E-Journal of Chemistry ◽

10.1155/2011/875896 ◽

2011 ◽

Vol 8 (4) ◽

pp. 1556-1565 ◽

Cited By ~ 2

Author(s):

A. S. Thakar ◽

K. S. Pandya ◽

K. T. Joshi ◽

A. M. Pancholi

Keyword(s):

Antibacterial Activity ◽

Metal Complexes ◽

Schiff Bases ◽

Mass Spectra ◽

Uv Spectra ◽

Assay Method ◽

H Nmr ◽

Ft Ir ◽

Schiff Base Metal Complexes ◽

C Nmr

Novel Schiff bases and their metal complexes were derived from some hetero cyclicβ-diketones with 4-phenyl-2-aminothiazole. All the synthesized compounds were confirmed their structure by Elemental analysis, FT-IR,1H NMR,13C NMR, Mass spectra, TGA analysis and UV spectra. All the compounds were tested for their antibacterial activity. Spectroscopic measurements suggest that all Schiff base metal complexes are of type ML2.(H2O)2(M=Mn, Fe, Co, Ni and Cu) and all the metal complexes shows moderate antibacterial activity in the agar cup assay method.

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Synthesis, Characterization, and Antimicrobial Activity Studies of Ni(II) Complex with Pyridine as a Ligand

Journal of Chemistry ◽

10.1155/2015/525239 ◽

2015 ◽

Vol 2015 ◽

pp. 1-8 ◽

Cited By ~ 2

Author(s):

Faridul Islam ◽

Md. Amran Hossain ◽

Nur Mostaq Shah ◽

Hridika Talukder Barua ◽

Md. Alamgir Kabir ◽

...

Keyword(s):

Antimicrobial Activity ◽

Nmr Spectra ◽

Conductivity Measurement ◽

Molar Conductivity ◽

Molecular Formula ◽

H Nmr ◽

Square Planar ◽

Elemental Analyses ◽

Prepared Complex ◽

C Nmr

We represent a metal complex which has been synthesized by the simple reaction with Ni(II) chloride and pyridine (as a lignd) affording a complex having the molecular formula [NiC5H5N2Cl2], characterized on the basis of elemental analyses, electronic, infrared,1H NMR,13C NMR spectra, magnetic susceptibility, and also aid of molar conductivity measurement. Conductivity measurement reveals nonelectrolytic nature of the complex. IR and13C NMR spectra reveal the presence ofcis- andtrans-structure. On the basis of above analyses the square planarcis- andtrans-structures are proposed for the prepared complex.

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Introduction of a novel nanosized N-sulfonated Brönsted acidic catalyst for the promotion of the synthesis of polyhydroquinoline derivatives via Hantzsch condensation under solvent-free conditions

RSC Advances ◽

10.1039/c6ra04148e ◽

2016 ◽

Vol 6 (31) ◽

pp. 26026-26037 ◽

Cited By ~ 41

Author(s):

Omid Goli-Jolodar ◽

Farhad Shirini ◽

Mohadeseh Seddighi

Keyword(s):

Sulfonic Acid ◽

Solvent Free ◽

Acidic Catalyst ◽

H Nmr ◽

Solvent Free Conditions ◽

Afm Analysis ◽

Hantzsch Condensation ◽

Different Types ◽

Ft Ir ◽

C Nmr

In this research NS-C4(DABCO-SO3H)2)·4Cl as a new nano sized N-sulfonic acid was prepared and characterized using different types of methods including FT-IR, 1H NMR, 13C NMR, mass, XRD, TGA, SEM and AFM analysis.

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