scholarly journals Experimental and modelling studies on antifungal compounds

2006 ◽  
Vol 4 (3) ◽  
pp. 428-439 ◽  
Author(s):  
Mukesh Doble ◽  
K. Kumar

AbstractAntifungal activity of organic compounds (aromatic, salicylic derivatives, cinnamyl derivatives etc) on Fusarium Rosium (14 compounds) and Aspergillus niger (17 compounds) was studied and QSAR models were developed relating molecular descriptors with the observed activity. Back propagation Neural Network models and single and multiple regression models were tested for predicting the observed activity. The data fit as well as the predictive capability of the neural network models were satisfactory (R2 = 0.84, q2 = 0.73 for Fusarium Rosium and R2 = 0.75, q2 = 0.62 for Aspergillus niger). The descriptors used in the network for the former were X4 (connectivity) and Jhetv (topological); and TIC1 (information) and SPI (topological) for the latter fungus. Antifungal activities of these organic compounds were generally lower against the latter than with the former fungus.

2012 ◽  
Vol 6-7 ◽  
pp. 1055-1060 ◽  
Author(s):  
Yang Bing ◽  
Jian Kun Hao ◽  
Si Chang Zhang

In this study we apply back propagation Neural Network models to predict the daily Shanghai Stock Exchange Composite Index. The learning algorithm and gradient search technique are constructed in the models. We evaluate the prediction models and conclude that the Shanghai Stock Exchange Composite Index is predictable in the short term. Empirical study shows that the Neural Network models is successfully applied to predict the daily highest, lowest, and closing value of the Shanghai Stock Exchange Composite Index, but it can not predict the return rate of the Shanghai Stock Exchange Composite Index in short terms.


The neural network models series used in the development of an aggregated digital twin of equipment as a cyber-physical system are presented. The twins of machining accuracy, chip formation and tool wear are examined in detail. On their basis, systems for stabilization of the chip formation process during cutting and diagnose of the cutting too wear are developed. Keywords cyberphysical system; neural network model of equipment; big data, digital twin of the chip formation; digital twin of the tool wear; digital twin of nanostructured coating choice


Symmetry ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 1082
Author(s):  
Fanqiang Meng

Risk and security are two symmetric descriptions of the uncertainty of the same system. If the risk early warning is carried out in time, the security capability of the system can be improved. A safety early warning model based on fuzzy c-means clustering (FCM) and back-propagation neural network was established, and a genetic algorithm was introduced to optimize the connection weight and other properties of the neural network, so as to construct the safety early warning system of coal mining face. The system was applied in a coal face in Shandong, China, with 46 groups of data as samples. Firstly, the original data were clustered by FCM, the input space was fuzzy divided, and the samples were clustered into three categories. Then, the clustered data was used as the input of the neural network for training and prediction. The back-propagation neural network and genetic algorithm optimization neural network were trained and verified many times. The results show that the early warning model can realize the prediction and early warning of the safety condition of the working face, and the performance of the neural network model optimized by genetic algorithm is better than the traditional back-propagation artificial neural network model, with higher prediction accuracy and convergence speed. The established early warning model and method can provide reference and basis for the prediction, early warning and risk management of coal mine production safety, so as to discover the hidden danger of working face accident as soon as possible, eliminate the hidden danger in time and reduce the accident probability to the maximum extent.


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