Headspace single-drop microextraction coupled with gas chromatography electron capture detection of butanone derivative for determination of iodine in milk powder and urine

AbstractA new detection method using headspace single-drop microextraction (HS-SDME) coupled to gas chromatography (GC) was established to determine the iodine in milk powder and urine. The derivative from the reaction between iodine and butanone in the acidic media was extracted into a micro-drop then determined by GC-ECD. With the optimisation of HS-SDME and derivatisation, the calibration curve showed good linearity within the range of 0.004–0.1 μg mL−1 (0.004–0.1 μg g−1) (R 2 = 0.9991), and the limits of detection for milk powder and urine were 0.0018 μg g−1 and 0.36 μg L−1, respectively. The mean recoveries of milk powder and urine were 90.0–107 % and 89.4–101 % with mean RSD of 1.7–3.4 % and 2.7–3.3 %, respectively. This detection method affords a number of advantages, such as being simple, rapid, and inexpensive, with low organic solvent consumption, and is remarkably free from interference effects, rendering it an efficient method for the determination of iodine in milk powder and urine samples.

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Application of single-drop microextraction coupled with gas chromatography for the determination of multiclass pesticides in vegetables with nitrogen phosphorus and electron capture detection

Journal of Chromatography A ◽

10.1016/j.chroma.2008.07.070 ◽

2009 ◽

Vol 1216 (14) ◽

pp. 2789-2797 ◽

Cited By ~ 50

Author(s):

E.G. Amvrazi ◽

N.G. Tsiropoulos

Keyword(s):

Gas Chromatography ◽

Electron Capture ◽

Electron Capture Detection ◽

Single Drop ◽

Single Drop Microextraction ◽

Nitrogen Phosphorus

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Application of single-drop microextraction and comparison with solid-phase microextraction and solid-phase extraction for the determination of α- and β-endosulfan in water samples by gas chromatography–electron-capture detection

Journal of Chromatography A ◽

10.1016/s0021-9673(02)01873-3 ◽

2003 ◽

Vol 984 (2) ◽

pp. 245-252 ◽

Cited By ~ 95

Author(s):

M.C López-Blanco ◽

S Blanco-Cid ◽

B Cancho-Grande ◽

J Simal-Gándara

Keyword(s):

Gas Chromatography ◽

Solid Phase Extraction ◽

Water Samples ◽

Solid Phase Microextraction ◽

Solid Phase ◽

Electron Capture Detection ◽

Phase Extraction ◽

Single Drop ◽

Single Drop Microextraction

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Single drop microextraction or solid phase microextraction–gas chromatography–mass spectrometry for the determination of iodine in pharmaceuticals, iodized salt, milk powder and vegetables involving conversion into 4-iodo-N,N-dimethylaniline

Journal of Chromatography A ◽

10.1016/j.chroma.2003.09.056 ◽

2004 ◽

Vol 1023 (1) ◽

pp. 33-39 ◽

Cited By ~ 62

Author(s):

P DAS ◽

M GUPTA ◽

A JAIN ◽

K VERMA

Keyword(s):

Mass Spectrometry ◽

Gas Chromatography ◽

Solid Phase Microextraction ◽

Solid Phase ◽

Milk Powder ◽

Iodized Salt ◽

Gas Chromatography Mass Spectrometry ◽

Single Drop ◽

Single Drop Microextraction

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Single-drop microextraction combined with gas chromatography-electron capture detection for the determination of acrylamide in food samples

Food Chemistry ◽

10.1016/j.foodchem.2018.08.108 ◽

2019 ◽

Vol 274 ◽

pp. 55-60 ◽

Cited By ~ 15

Author(s):

Mohammad Saraji ◽

Salman Javadian

Keyword(s):

Gas Chromatography ◽

Electron Capture ◽

Food Samples ◽

Electron Capture Detection ◽

Single Drop ◽

Single Drop Microextraction

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Determination of ethyl carbamate in wine by matrix modification-assisted headspace single-drop microextraction and gas chromatography-mass spectrometry technique

Food Chemistry ◽

10.1016/j.foodchem.2021.131573 ◽

2021 ◽

pp. 131573

Author(s):

Zexin Ma ◽

Tingyong Zhao ◽

Shiyao Cui ◽

Xiaoning Zhao ◽

Yong Fan ◽

...

Keyword(s):

Mass Spectrometry ◽

Gas Chromatography ◽

Ethyl Carbamate ◽

Gas Chromatography Mass Spectrometry ◽

Single Drop ◽

Single Drop Microextraction ◽

Mass Spectrometry Technique ◽

Matrix Modification ◽

Spectrometry Technique

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Determination of Chlorobenzenes in Wastewater by Single-Drop Microextraction Coupled to Capillary Gas Chromatography

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.838-841.2566 ◽

2013 ◽

Vol 838-841 ◽

pp. 2566-2569

Author(s):

Jian Qi Sun ◽

Bo Qiao ◽

Jun Dai

Keyword(s):

Gas Chromatography ◽

Capillary Gas Chromatography ◽

Preparation Technique ◽

Single Drop ◽

Flame Ionization ◽

Single Drop Microextraction ◽

Relative Standard ◽

Efficient Recovery ◽

Wastewater Samples

This study describes an analytical method employing capillary gas chromatography (GC) using flame ionization detection (FID) that has been developed for the simultaneous determination of chlorobenzenes (m-dichlorobenzene (m-DCB),p-dichlorobenzene (p-DCB),o-dichlorobenzene (o-DCB) and 1,2,4-trichlorobenzene (1,2,4-TCB)) in wastewater. For this purpose, single-drop microextraction (SDME) was applied as a sample preparation technique. The SDME parameters such as types of extractants, volume of the microdroplet size, extraction time, stir rate and immersion depth of needle point were studyed and optimized. The method was linear in the ranges from 4.0×10-3to 40.0 μg·mL-1form-DCB,p-DCB ando-DCB, and 4.0×10-3to 30.0 μg·mL-1for 1,2,4-TCB withR2≥0.9955. The SDME procedure allowed efficient recovery of the investigated chlorobenzenes ranging between 80 % and 105 % with a relative standard deviation (RSD) ≤6.5 for actual wastewater sampes spiked with 2, 5 and 10 μg·mL-1of chlorobenzes, respectively. These results showed the potential of this technique for chlorobenzenes monitoring in wastewater samples. Furthermore, the investigated methods are simple, reliable, reproducible, and not expensive.

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Determination of Volatile Halogenated Hydrocarbons in Wastewater by Single-Drop Microextraction Coupled to Capillary Gas Chromatography

Applied Mechanics and Materials ◽

10.4028/www.scientific.net/amm.295-298.487 ◽

2013 ◽

Vol 295-298 ◽

pp. 487-491

Author(s):

Jian Qi Sun

Keyword(s):

Gas Chromatography ◽

Capillary Gas Chromatography ◽

Halogenated Hydrocarbons ◽

Wastewater Sample ◽

Single Drop ◽

Single Drop Microextraction ◽

Relative Standard ◽

Wastewater Samples ◽

Volatile Halogenated Hydrocarbons

Single-drop microextraction (SDME) coupled to capillary gas chromatography (GC) was established for the determination of seven volatile halogenated hydrocarbons in wastewater, including chloroform (CF), carbon tetrachloride (CT), trichloroethylene (TCE), bromodichloromethane (BDCM), perchlorethylene (PCE), dibromochloromethane (DBCM) and bromoform (BF). The SDME parameters such as extractants, extracting time，stirring rate and immerging depth of needle point were studyed and optimized. The abovementioned halogenated hydrocarbons were quantified by external standardization method using GC coupled with a flame ionization detector (FID). The linear regression calibration curves, detection limits (S/N=3) and the linear ranges of the method for determining each halogenated hydrocarbons were determined, respectively. The concentrations of componds abovementioned in a real wastewater sample, the average of the recoveries obtained in the spiked wastewater samples and the corresponding relative standard deviations were determined, respectively. The results showed the proposed method several attributes, friendly enviroment, economic and highly efficient pretreatment, less time, simplicity, sensitivity, accuracy and wide linear range and so on.

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