scholarly journals Giant Basal Cell Carcinoma – a Case Report

2018 ◽  
Vol 10 (3) ◽  
pp. 83-89
Author(s):  
Igor Kapetanović ◽  
Vesna Reljić ◽  
Martina Bosić ◽  
Svetlana Popadić
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Slow Growth ◽  
Rare Type ◽  
Basal Cell Carcinomas ◽  
The Right ◽  
Electron Radiotherapy ◽  
Giant Basal Cell Carcinoma ◽  
Cutaneous Cancer

Abstract Basal cell carcinoma is the most common form of cutaneous cancer. In majority of cases it is locally invasive with slow growth, ranging in size from a couple of milimeters to a couple of centimeters and located primarily on sun-exposed regions. Giant basal cell carcinoma, defined as a tumor that is larger than 5 cm in diameter, is a very rare type of cutaneous malignancy accounting for 0.5-1% of all basal cell carcinomas. We present a case of a 74-year-old man with a 17 x 14 cm giant basal cell carcinoma in the right supraclavicular region. Detailed history revealed that the lesion had started as a papule 15 years before presentation. Despite its growth, the lesion was neglected until admission. Histological examination of skin lesion confirmed superficial and focally infiltrative types of basal cell carcinoma. Electron radiotherapy was administered with 54 Gy total dose delivered in 20 daily fractions which resulted in healing of lesions and adequate response. Thus, definitive radiotherapy can be just as effective as excision when the criteria are met.

scholarly journals Locally advanced basal cell carcinoma of the auricle and parotid region: A case report

2021 ◽  
Vol 68 (2) ◽  
pp. 94-98
Author(s):  
Srdjan Milanovic ◽  
Suzana Stojanovic-Rundic ◽  
Nikola Milosevic ◽  
Branko Dozic ◽  
Marko Dozic
Keyword(s):  
Case Report ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Multidisciplinary Approach ◽  
Locally Advanced ◽  
Parotid Region ◽  
Basal Cell Carcinomas ◽  
The Right ◽  
Advanced Basal Cell Carcinoma

Skin cancers are the most common malignant tumors in general. The most significant risk factor is exposure to UV radiation. They mainly occur in the head and neck region, and the majority of about 80% are basal cell carcinomas. Surgery is standard treatment of uncomplicated basal cell carcinomas, but a multidisciplinary approach is necessary in advanced cases. The case report refers to a patient with locally advanced recurrent basal cell carcinoma with primary tumor localization in the right auricle and parotid region in 2012 when primary surgery was performed. Due to the local recurrence, amputation of the right auricle and trepanation of the mastoid process was done in November 2018, and after that, radiation therapy of a recurrent tumor in the area of the trepanation cavity was applied. In the course of follow-up so far, there is good local control, without signs of toxicity. The case report points to the importance of a multidisciplinary approach and the role of radiotherapy in the treatment and control of advanced basal cell carcinoma of this region.

scholarly journals Giant Basal Cell Carcinoma: A Case Report

2018 ◽  
Vol 35 (2) ◽  
pp. 149-155
Author(s):  
Danijela Popović ◽  
Andrija Jović ◽  
Danica Tiodorović ◽  
Nataša Vidović ◽  
Ivana Graovac
Keyword(s):  
Case Report ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Human Population ◽  
Common Type ◽  
Rare Type ◽  
Clinical Variants ◽  
Aggressive Tumors ◽  
Giant Basal Cell Carcinoma

Abstract Basal cell carcinoma (BCC) is the most common type of skin cancer and the most common type of tumor in the human population in general. Clinical variants of BCC include nodular, superficial, pigmented, morpheaform, cystic, metatypical types and fibroepithelioma of Pinkus. Giant BCC is a rare type of carcinoma, accounting for less than 1% of all cases of BCC. Most often they occur on the trunk. BCC belongs to the group of aggressive tumors, leading to the invasion of deeper tissues, and examples of metastasis of this type of tumor can be found in the reference literature. In this case report, we present a case of a 76-year-old female patient with a giant ulcerous form of basal cell carcinoma on the back.

scholarly journals Giant basal cell carcinoma

2012 ◽  
Vol 87 (3) ◽  
pp. 469-471 ◽  
Author(s):  
Nilton Nasser ◽  
Nilton Nasser Filho ◽  
Bruno Trauczynski Neto ◽  
Lissandra Melati da Silva
Keyword(s):  
Surgical Treatment ◽  
Local Recurrence ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Rare Form ◽  
Common Skin ◽  
The Right ◽  
Giant Basal Cell Carcinoma

The basal cell carcinoma is the most common skin cancer but the giant vegetating basal cell carcinoma reaches less than 0.5 % of all basal cell carcinoma types. The Giant BCC, defined as a lesion with more than 5 cm at its largest diameter, is a rare form of BCC and commonly occurs on the trunk. This patient, male, 42 years old presents a Giant Basal Cell Carcinoma which reaches 180 cm2 on the right shoulder and was negligent in looking for treatment. Surgical treatment was performed and no signs of dissemination or local recurrence have been detected after follow up of five years.

scholarly journals Giant morphea-form basal cell carcinoma of the umbilicus: Successful debulking with vismodegib

Rare Tumors ◽  
2018 ◽  
Vol 10 ◽  
pp. 203636131877293 ◽  
Author(s):  
Mariana Orduz Robledo ◽  
Eve Lebas ◽  
Marie-Annick Reginster ◽  
Mahmoud Baghaie ◽  
Sabine Groves ◽  
...  
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Treatment Plan ◽  
Sequential Treatment ◽  
Basal Cell Carcinomas ◽  
Cd56 Expression ◽  
Main Representative ◽  
Form Type ◽  
Giant Basal Cell Carcinoma

Basal cell carcinoma of the umbilicus is very rare. The nodular subtype is the main representative. Giant basal cell carcinomas represent around 1% of all basal cell carcinomas. The hedgehog pathway inhibitor vismodegib is indicated for advanced basal cell carcinoma and CD56-negative immunostaining seems indicative for successful treatment. A 54-year-old man presented a 10 cm × 14 cm large and 4.5 cm deep morphea-form basal cell carcinoma with faint immunohistochemical CD56 expression arising from the umbilicus. A sequential treatment was initiated with debulking using vismodegib 150 mg per day for 4 months, followed by reconstructive surgery. To the best of our knowledge, this is the first report of a giant basal cell carcinoma of the morphea-form type of the umbilicus. The sequential treatment plan reduces the duration of vismodegib inherent adverse effects and significantly reduces the tumor mass prior to surgery. Besides increasing adherence to vismodegib treatment, this approach facilitates the surgical technique and improves cosmetic outcome.

scholarly journals Comparative Analysis of the Applicability of Island Flap in Primary and Recurrent Basal Cell Carcinomas of Similar Localization

2018 ◽  
Vol 6 (6) ◽  
pp. 1077-1080
Author(s):  
Georgi Tchernev ◽  
Ivanka Temelkova ◽  
Hristo Mangarov ◽  
Konstantin Stavrov
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Surgical Excision ◽  
Good Prognosis ◽  
Individual Risk ◽  
Complete Surgical Excision ◽  
Basal Cell Carcinomas ◽  
The Individual ◽  
The Right

BACKGROUND: Basal cell carcinoma belongs to non-melanoma skin cancers and is the most prevalent neoplasia that shows a tendency to increase over the last few decades. It occurs most often in skin areas exposed to sunlight. It is characterised by slow progression, low tendency to metastasising and good prognosis when the right choice of treatment has been made. The difficulty in the treatment of basal cell carcinomas is determined by their localisation and puts to the test the aesthetic potential of dermatosurgeons. Complete surgical excision is the standard approach in most uncomplicated cases. In relapsing basal cell carcinoma or carcinoma with aggressive or unfavourable histopathological characteristics, the clinician faces the dilemma of identifying the most appropriate method of treatment. To find the decision, help comes from the individualisation of each case and the related risk factors.CASE REPORT: Two cases of basal cell carcinoma of similar localisation are presented, where the carcinomas are removed using island flaps. In spite of the desire to observe the recommended field of surgical security (by the desire for the ultimate esthetic effect for the patient), one of the tumours was not completely removed, and as an alternative, reoperation was proposed using Mohs micrographic surgery (MMS).CONCLUSION: The choice of a surgical technique, which would guarantee a better outcome and could be applied depending on the individual risk factor in each patient, is discussed.

Two Cases of Giant Basal Cell Carcinoma of the Vulva

2005 ◽  
Vol 67 (6) ◽  
pp. 584-589 ◽  
Author(s):  
Tadamasa YAMAMOTO ◽  
Sachiko TAKEICHI ◽  
Daisuke FUKUMOTO ◽  
Hirotsugu TAKIWAKI ◽  
Seiji ARASE ◽  
...  
Keyword(s):  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Giant Basal Cell Carcinoma

Basal Cell Carcinoma of Prostate With MSMB–NCOA4 Fusion and a Probable Basal Cell Carcinoma In Situ: Case Report

2021 ◽  
pp. 106689692110173
Author(s):  
Vilde Pedersen ◽  
Katrine S. Petersen ◽  
Klaus Brasso ◽  
Olga Østrup ◽  
Anand C. Loya
Keyword(s):  
Prostate Cancer ◽  
Basal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Basal Cell ◽  
Carcinoma In Situ ◽  
Pathological Examination ◽  
Molecular Characteristics ◽  
Histological Lesion ◽  
Basal Cell Carcinomas

Basal cell carcinomas of prostate (BCCP) are very rare. Most arise in the transition zone and thus are associated with lower urinary tract symptoms and rarely associated with elevated prostate-specific antigen (PSA). These features make diagnosis/early diagnosis difficult because of the routine protocols followed. Basal cell carcinomas have distinctive histopathological, immunohistochemical, and to some extent also different molecular characteristics. Basal cell carcinoma in situ (BCCIS) is a nonexistent histological lesion as per the current literature, but here is an attempt to describe it through this case. A 74-year-old man presented with hematuria and previous diagnosis of prostatic hyperplasia. Based on this history, he underwent a prostatectomy ad modum Freyer. Pathological examination surprisingly revealed a diffusely infiltrative tumor with nonacinar adenocarcinoma morphology and many glandular structures probably representing BCCIS. Tumor was diagnosed as BCCP. Patient presented with metastasis to the abdominal wall 8 months postprostatectomy. BCCP is an aggressive type of prostate cancer, which might be challenging to diagnose based on routine protocols. This results in delayed diagnosis and treatment and thus poor prognosis. Furthermore, patients with this subtype of prostate cancer need appropriately designed, and maybe a totally different follow-up regimen as PSA is of no use for BCCP patients. Finally, diagnosis of BCCIS, if agreed upon its existence needs to be studied in larger cohorts as a precursor lesion.

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