scholarly journals URGENT DIAGNOSTICS OF CEREBRAL VENOUS TROMBOSIS

2016 ◽  
Vol 175 (5) ◽  
pp. 18-25 ◽  
Author(s):  
L. M. Tibekina ◽  
T. A. Shumakova ◽  
A. A. Nikolaeva ◽  
Yu. A. Shcherbuk
Keyword(s):  
Ischemic Stroke ◽  
Reference Range ◽  
Comparison Group ◽  
Clinical Laboratory ◽  
Diagnostic Algorithm ◽  
Information Value ◽  
Cerebral Veins ◽  
Elevated Protein ◽  
Clinical Syndromes ◽  
Deep Cerebral Veins

Investigations were carried out in 24 patients in order to evaluate information value of the data of clinical, laboratory, neuroradiological methods of research and develop the diagnostic algorithm in case of cerebral venous thrombosis (CVT). The main group consisted of 11 patients (7 male, 4 female, average age 49,1±4,3) with CVT. The comparison group included 13 patients (6 male, 7 female; average age 68,1±9,5) with ischemic stroke (IS) of moderate severity. There were revealed changes in blood and cerebrospinal fluid (CSF) as form of leukocytosis of blood and moderately increased cell count with elevated protein in CSF and blood in case of CTV. The authors noted an elevated protein in CSF and blood and leukocytosis with predominant lymphopenia in blood and neurophilic predominance in CSF within the reference range of CSF in patient with ischemic stroke. The epileptic attacks, meningeal syndromes, headaches were more often among clinical syndromes at CTV than in case of ischemic stroke. The algorithm of neuroimaging research methods and modes of MRI were determined and allowed an effective diagnostics of damages of venous sinuses, superficial and deep cerebral veins in case of urgent hospitalization of patients. It was possible to suggest the venous pathology in 7 (63,6%) cases due to SKT (without contrast) and in case of application of MR venography (2D TOFmode), there were revealed 100% of cases.

scholarly journals Clinical, laboratory and instrumental criteria for myocarditis, established in comparison with myocardial biopsy: A non-invasive diagnostic algorithm

2017 ◽  
Vol 89 (9) ◽  
pp. 30-40 ◽  
Author(s):  
O V Blagova ◽  
Yu V Osipova ◽  
A V Nedostup ◽  
E A Kogan ◽  
V A Sulimov
Keyword(s):  
Heart Surgery ◽  
Comparison Group ◽  
Clinical Laboratory ◽  
Inflammatory Diseases ◽  
Open Heart Surgery ◽  
Diagnostic Algorithm ◽  
Diagnostic Value ◽  
Left Ventricular ◽  
Study Group ◽  
Morphological Examination

Aim. To determine the diagnostic value of different clinical, laboratory, and instrumental signs in the diagnosis of myocarditis in patients with the picture of idiopathic arrhythmias, dilated cardiomyopathy (DCM) and in a comparison group when comparing with myocardial morphological examination. Subjects and methods. A study group included 100 patients (35 women; mean age, 44.7±12.5 years) with idiopathic arrhythmias (n=20) and DCM as a syndrome (n=100). All underwent myocardial morphological examination: endomyocardial biopsy (EMB) (n=71), intraoperative biopsy (n=13), study of the explanted heart (n=6), and autopsy (n=11). A comparison group consisted of 50 patients (25 women; mean age, 53.7±11.7 years) with non-inflammatory diseases of the heart (left ventricular end-diastolic dimension 50%) who underwent open-heart surgery (n=47), EMB (n=2), or autopsy (n=1). The investigators also performed polymerase chain reaction for cardiotropic viral DNA in the blood and myocardium, anticardiac antibody (ACA) identification, myocardial scintigraphy (n=26), coronary angiography (n=47), magnetic resonance imaging (MRI) (n=25), and multislice computed tomography of the heart (n=45). The diagnostic value of the extended spectrum of clinical, laboratory, and instrumental markers for myocarditis was estimated. Results. Active/borderline myocarditis was diagnosed in 76% of the patients in the study group (75.5% in the arrhythmia subgroup and 76.3% in the DCM one) and in 24.3% of those in the comparison group (p

Clinical diagnostic algorithm for determining subtype of ischemic stroke in patientsof integrated stroke block

2020 ◽  
Vol 0 (1—2) ◽  
pp. 20-27
Author(s):  
Y. V. Flomin ◽  
G. S. Trepet ◽  
V. G. Guryanov ◽  
L. I. Sokolova
Keyword(s):  
Ischemic Stroke ◽  
Diagnostic Algorithm ◽  
Clinical Diagnostic

scholarly journals 2019 novel coronavirus disease with secondary ischemic stroke: two case reports

BMC Neurology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Bin Fu ◽  
Yun Chen ◽  
Ping Li
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
Clinical Laboratory ◽  
Case Reports ◽  
Small Vessel ◽  
Vessel Occlusion ◽  
Aged Patients ◽  
Health Crisis ◽  
Physical Examinations ◽  
Novel Coronavirus

Abstract Background The COVID-19 pandemic, which broke out in Wuhan in 2019, has become the global health crisis of our time. Elderly patients with certain fundamental diseases are more likely to develop severe cases. The secondary lesion following viral infection have only rarely been reported. Case presentation We here report two cases of coronavirus-infected pneumonia with acute ischemic stroke in middle-aged patients. In both COVID-19 cases, neurological physical examinations showed normal results before infection. Lymphocytopenia, accompanied by elevated cytokines and D-dimers, were found from serum clinical laboratory examination at admission. Dysarthria and limb muscle weakness are initial manifestations, occurring one week after infect-causative pathogen, SARS-CoV-2. The head CT and head/neck arterial CTA showed small-vessel occlusion. The patients were diagnosed with coronavirus diseases with secondary acute ischemic stroke. They were treated with tirofiban and followed up with daily aspirin and atorvastatin. Conclusions These cases suggested that secondary ischemic stroke, mainly manifested as small-vessel occlusion, should be considered for COVID-19 patients and diagnosed and treated promptly.

Thrombosis of the deep cerebral veins: CT and MRI findings with pathologic correlation

1997 ◽  
Vol 39 (11) ◽  
pp. 777-780 ◽  
Author(s):  
A. Madan ◽  
M. Sluzewski ◽  
W. J. J. van Rooij ◽  
C. C. Tijssen ◽  
J. L. J. M. Teepen
Keyword(s):  
Cerebral Veins ◽  
Mri Findings ◽  
Pathologic Correlation ◽  
Deep Cerebral Veins ◽  
Ct And Mri

The treatment effi cacy of disturbed swallowing function in patients with ischemic stroke and neurogenic dysphagia

2021 ◽  
Vol 26 (3) ◽  
pp. 51-57
Author(s):  
V. I. Ershov ◽  
A. A. Borzdyko ◽  
V. V. Silkin
Keyword(s):  
Ischemic Stroke ◽  
Combination Therapy ◽  
Comparison Group ◽  
Dynamic Assessment ◽  
Control Group ◽  
Training Method ◽  
Severity Scale ◽  
Neurogenic Dysphagia ◽  
Swallowing Function ◽  
Penetration Aspiration Scale

The aim. To evaluate the effi cacy of swallowing recovery of patients with ischemic stroke carried out with the use of training rehabilitation method using special nutrient mixtures as part of combination therapy. Material and methods. The study included 65 patients (35 men and 30 women, aged 45 to 80 years) with dysphagia in the acute period of ischemic stroke. Thirty patients (control group) were treated with special binding compounds as part of a combination therapy. Thirty fi ve patients (comparison group) did not use the mixture. The dynamics of the recovery function of swallowing using the Penetration–Aspiration Scale (PAS) and the Fiberoptic Endoscopic Dysphagia Severity Scale (FEDSS), as well as the transition from tube to independent feeding were studied. Results. The training method of rehabilitation using special nutritional mixtures is eff ective assessed with PAS and FEDSS in patients with ischemic stroke and neurogenic dysphagia (p < 0.05). The most pronounced eff ect was achieved in the group of patients with pseudobulbar syndrome. In patients with bulbar syndrome no statistically signifi cant diff erences were observed in the dynamic assessment of the severity of dysphagia on the PAS and FEDSS scales. The application of the training method leads to a signifi cantly better transition from tube to independent feeding. Conclusion. The training method of rehabilitation using special nutritional mixtures is eff ective in patients with ischemic stroke and neurogenic dysphagia and leads to a signifi cantly better transition from tube to independent feeding.

scholarly journals Falco-Tentorial Meningioma Producing Irreversible Midbrain Damage

2014 ◽  
Vol 21 (3) ◽  
pp. 301-304
Author(s):  
Amit Agrawal
Keyword(s):  
Ct Scan ◽  
Obstructive Hydrocephalus ◽  
Fatal Outcome ◽  
Surgical Decompression ◽  
Cerebral Veins ◽  
Tentorial Meningioma ◽  
Brain Surface ◽  
Deep Cerebral Veins ◽  
History Of ◽  
The Brain

Abstract Meningiomas arising from the falcotentorial junction are the rarest subgroup of tentorial menigiomas. Because of the distance from the brain surface and the surrounding deep cerebral veins these lesions are difficult and dangerous to treat surgically. A 45-year-old female presented with the history of progressive headache, disorientation, unsteadiness, and urinary incontinence for over 6 months. The patient developed difficulty in swallowing, and weakness of all four limbs for the last 7 days. CT scan brain plain and contrast showed a large well defined, homogenously enhancing mass lesion in the peineal region with compression of the upper brain stem and obstructive hydrocephalus. Inspite of the good surgical decompression the patient did not do well. As described in the literature, the compression of the midbrain can cause severe respiratory disturbances with fatal outcome; probably the similar mechanism resulted in poor outcome in present case. As we noticed the diffuse hypodensity in midbrain on CT scan, similar findings have been described in literature in cases of transtentorial herniation with poorer outcome.

scholarly journals MODERN METHODS OF PREVENTION AND TREATMENT OF COMPLICATIONS OF CERVICAL ESOPHAGO-ORGAN ANASTOMOSIS AT ESOPHAGOPLASTY

2020 ◽  
Vol 73 (8) ◽  
pp. 1696-1699
Author(s):  
Volodymyr O. Shaprynskyi ◽  
Yevhen V. Shaprynskyi ◽  
Mustafa Bassam Hussein ◽  
Oleg O. Vorovskyi ◽  
Yaroslav V. Karyi ◽  
...  
Keyword(s):  
Operative Treatment ◽  
Postoperative Period ◽  
Comparison Group ◽  
Postoperative Mortality ◽  
Diagnostic Algorithm ◽  
Main Group ◽  
Instrumental Method ◽  
Complication Risk ◽  
Esophageal Strictures ◽  
Bed Days

The aim: To improve the results of operative treatment of esophageal strictures by decreasing the rate of failure and stricture of cervical esophago-organ anastomoses. Materials and methods: There were 45 patients with post-burn corrosive gullet strictures, 17 patients with postoperative corrosive strictures, 10 patients with peptic strictures secondary to reflux-esophagitis, 42 patients with esophageal cancer strictures. The patients were divided into two groups: the comparison group – 55 persons and the main group – 59 persons. Patients of comparison group underwent surgical treatment of esophageal strictures according to classic protocols and standards. In the main group of patients we applied proposed diagnostic algorithm with prediction of complication risk and the designed method of esophago-organ anastomosis formation. Results: The results of operative treatment in patients with esophageal strictures showed the development of early postoperative complications in 59 individuals (51.75 %). In the postoperative period six patients died: four – in the comparison group and two – in the main group. Failure of cervical esophago-organ anastomosis and esophageal strictures occurred in 7 patients (11.86 %) of main group and 20 patients (36.36 %) of the comparison group (p<0.05). Conclusions: Application of method predicting the risk of complications of cervical anastomosis, treatment program and instrumental method of formation anastomosis resulted in reduced incidence of failure and strictures of esophago-organ anastomosis from 36.36 % to 11.86 % (p<0.05); decreased time of hospitalization - from 28.2 ± 1.1 to 21.5 ± 0.5 bed-days (p<0.001), postoperative period - from 20.5 ± 1.1 to 16.1 ± 0.7 bed-days (p<0.01); decreased postoperative mortality - from 7.27 % to 3.39 %.

scholarly journals DIAGNOSIS OF VENOUS ISCHEMIC STROKE. PART II (ALGORITHMS AND SEMIOLOGY OF DIAGNOSTIC RADIOLOGY. LIMITATIONS IN CLINICAL PRACTICE). A REVIEW

2019 ◽  
Vol 8 (3) ◽  
pp. 104-115
Author(s):  
S. E. Semenov ◽  
E. A. Yurkevich ◽  
I. V. Moldavskaia ◽  
M. G. Shatokhina ◽  
A. S. Semenov
Keyword(s):  
Ischemic Stroke ◽  
Transcranial Doppler ◽  
Sinus Thrombosis ◽  
Pathological Condition ◽  
Diagnostic Algorithm ◽  
Diagnostic Procedures ◽  
Cerebral Venous Sinus Thrombosis ◽  
Standards Of Care ◽  
Unstable Process ◽  
Venous Stroke

Venous stroke in cerebral venous sinus thrombosis is a rare pathological condition with uncertain diagnostic algorithm to ensure prompt treatment by neurologists and radiologists. All the methods are not obligatory in the workup of acute stroke, except computed tomography (CT) and transcranial Doppler. Researchers and clinicians are commonly guided by their own experiences. Therefore, the diagnosis of venous stroke is an unstable process resulting in its underestimation in the general stroke population. The optimal use of neuroimaging methods within the existing standards of care for patients with stroke, determination of the necessary and sufficient set of diagnostic procedures is an organizational and methodical problem. In addition, there is no complete description of venous ischemic stroke patterns in the medical literature. The article reviews existing evidence-based data on the diagnostic algorithms for venous stroke and discusses the probability of detecting radiologic symptoms based on the diagnostic accuracy and effectiveness of such methods as conventional CT and magnetic resonance imaging (MRI), CT and MR angiography, CT and MR perfusion, transcranial Doppler (TCD) and ultrasound of the brachiocephalic arteries stated in the national and international guidelines, as well as our own experience. Limitations of their use and options to overcome major drawbacks including the introduction of teleradiology are considered.

Deep Cerebral Veins

1976 ◽  
pp. 210-261 ◽  
Author(s):  
Georges Salamon ◽  
Yun Peng Huang ◽  
P. Michotey ◽  
N. Moscow ◽  
Ch. Raybaud ◽  
...  
Keyword(s):  
Cerebral Veins ◽  
Deep Cerebral Veins

Analysis of On-Line Clinical Laboratory Manuals and Practical Recommendations

2004 ◽  
Vol 128 (4) ◽  
pp. 476-479
Author(s):  
Bruce Beckwith ◽  
Robert Schwartz ◽  
Liron Pantanowitz
Keyword(s):  
Reference Range ◽  
Clinical Laboratory ◽  
Critical Values ◽  
Supplementary Information ◽  
Reference Ranges ◽  
Individual Test ◽  
Test Methodology ◽  
Laboratory Manuals ◽  
On Line ◽  
Data Elements

Abstract Context.—On-line clinical laboratory manuals are a valuable resource for medical professionals. To our knowledge, no recommendations currently exist for their content or design. Objective.—To analyze publicly accessible on-line clinical laboratory manuals and to propose guidelines for their content. Design.—We conducted an Internet search for clinical laboratory manuals written in English with individual test listings. Four individual test listings in each manual were evaluated for 16 data elements, including sample requirements, test methodology, units of measure, reference range, and critical values. Web sites were also evaluated for supplementary information and search functions. Results.—We identified 48 on-line laboratory manuals, including 24 academic or community hospital laboratories and 24 commercial or reference laboratories. All manuals had search engines and/or test indices. No single manual contained all 16 data elements evaluated. An average of 8.9 (56%) elements were present (range, 4–14). Basic sample requirements (specimen and volume needed) were the elements most commonly present (98% of manuals). The frequency of the remaining data elements varied from 10% to 90%. Conclusions.—On-line clinical laboratory manuals originate from both hospital and commercial laboratories. While most manuals were user-friendly and contained adequate specimen-collection information, other important elements, such as reference ranges, were frequently absent. To ensure that clinical laboratory manuals are of maximal utility, we propose the following 13 data elements be included in individual test listings: test name, synonyms, test description, test methodology, sample requirements, volume requirements, collection guidelines, transport guidelines, units of measure, reference range, critical values, test availability, and date of latest revision.

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