scholarly journals ANALISIS KINERJA TIANG DENGAN VARIASI KEMIRINGAN DI DERMAGA “SJ” BANDAR LAMPUNG

2021 ◽  
Vol 4 (4) ◽  
pp. 823
Author(s):  
Dede Oktaferdian ◽  
Sunarjo Leman

The design of the jetty cannot be separated from the use of piles as a foundation that supports the upper structure. The pile configuration affects the strength and stability of the structure. It may consist of only vertical piles or a combination of vertical and batter piles. This study analyzes and compares 10 types of pile configurations intending to determine the best pile configuration among the types analyzed. Type 1 is a pile configuration that is in accordance with the field planning of “SJ” jetty which consists of only vertical piles and type 2 to type 10 is a pile configuration that consists of a combination of vertical and batter piles with a slope ranging from 1H:12V to 1H:4V. The best configuration is determined based on the strength (capacity ratio), stiffness (deflection that occurs), and the axial bearing capacity of the pile. The process of modeling and analyzing the pile configurations are done using Midas Gen. The results showed that pile configuration type 8 with a combination of vertical and batter piles with a slope of 1H:6V is the best configuration with the smallest deflection and the axial forces of the vertical and batter piles are almost equal.ABSTRAKDesain dermaga tidak dapat dipisahkan dari penggunaan tiang sebagai fondasi yang menyangga struktur bagian atas. Konfigurasi tiang berpengaruh pada kekuatan dan stabilitas dari struktur dermaga. Konfigurasi tiang dapat terdiri dari tegak seluruhnya maupun kombinasi antara tiang tegak dan miring. Penelitian ini menganalisis dan membandingkan 10 tipe konfigurasi tiang dengan tujuan mendapatkan konfigurasi tiang terbaik di antara tipe-tipe yang dianalisis. Tipe 1 adalah konfigurasi tiang yang sesuai dengan perencanaan dermaga “SJ” berupa tiang tegak seluruhnya dan tipe 2 hingga tipe 10 adalah konfigurasi kombinasi tiang tegak dan miring dengan kemiringan 1H:12V hingga 1H:4V. Konfigurasi tiang terbaik ditentukan berdasarkan kekuatan (capacity ratio), kekakuan (defleksi yang terjadi), dan daya dukung aksial tiang. Model dan proses analisis dari seluruh konfigurasi tiang menggunakan program Midas Gen. Hasil analisis menunjukkan bahwa konfigurasi tiang tipe 8 dengan kombinasi tiang tegak dan miring dengan kemiringan 1H:6V adalah konfigurasi terbaik dengan defleksi terkecil serta gaya aksial tiang tegak dan miring yang hampir sama.

2008 ◽  
Vol 38 (15) ◽  
pp. 18
Author(s):  
SHERRY BOSCHERT
Keyword(s):  

2010 ◽  
Vol 30 (S 01) ◽  
pp. S150-S152
Author(s):  
G. Jiménez-Cruz ◽  
M. Mendez ◽  
P. Chaverri ◽  
P. Alvarado ◽  
W. Schröder ◽  
...  

SummaryHaemophilia A (HA) is X-chromosome linked bleeding disorders caused by deficiency of the coagulation factor VIII (FVIII). It is caused by FVIII gene intron 22 inversion (Inv22) in approximately 45% and by intron 1 inversion (Inv1) in 5% of the patients. Both inversions occur as a result of intrachromosomal recombination between homologous regions, in intron 1 or 22 and their extragenic copy located telomeric to the FVIII gene. The aim of this study was to analyze the presence of these mutations in 25 HA Costa Rican families. Patients, methods: We studied 34 HA patients and 110 unrelated obligate members and possible carriers for the presence of Inv22or Inv1. Standard analyses of the factor VIII gene were used incl. Southern blot and long-range polymerase chain reaction for inversion analysis. Results: We found altered Inv22 restriction profiles in 21 patients and 37 carriers. It was found type 1 and type 2 of the inversion of Inv22. During the screening for Inv1 among the HA patient, who were Inv22 negative, we did not found this mutation. Discussion: Our data highlight the importance of the analysis of Inv22 for their association with development of inhibitors in the HA patients and we are continuous searching of Inv1 mutation. This knowledge represents a step for genetic counseling and prevention of the inhibitor development.


1994 ◽  
Vol 71 (06) ◽  
pp. 731-736 ◽  
Author(s):  
M W Mansfield ◽  
M H Stickland ◽  
A M Carter ◽  
P J Grant

SummaryTo identify whether genotype contributes to the difference in PAI-1 levels in type 1 and type 2 diabetic subjects and whether genotype relates to the development of retinopathy, a Hind III restriction fragment length polymorphism and two dinucleotide repeat polymorphisms were studied. In 519 Caucasian diabetic subjects (192 type 1, 327 type 2) and 123 Caucasian control subjects there were no differences in the frequency of the Hind III restriction alleles (type 1 vs type 2 vs control: allele 1 0.397 vs 0.420 vs 0.448; allele 2 0.603 vs 0.580 vs 0.552) nor in the allelic frequency at either dinucleotide repeat sequence. In 86 subjects with no retinopathy at 15 years or more from diagnosis of diabetes and 190 subjects with diabetic retinopathy there was no difference in the frequency of Hind III restriction alleles (retinopathy present vs retinopathy absent: allele 1 0.400 vs 0.467; allele 2 0.600 vs 0.533) nor in the allelic frequencies at either dinucleotide repeat sequence. The results indicate that there is no or minimal influence of the PAI-1 gene on either PAI-1 levels or the development of diabetic retinopathy in patients with diabetes mellitus.


2017 ◽  
Author(s):  
Marwa Omri ◽  
Rayene Ben Mohamed ◽  
Imen Rezgani ◽  
Sana Mhidhi ◽  
Aroua Temessek ◽  
...  

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