scholarly journals Living systems, ‘total design’ and the evolution of the automobile: the significance and application of holistic design methods in automotive design, manufacture and operation

Author(s):  
D. Andrews ◽  
P. Nieuwenhuis ◽  
P.D. Ewing
1997 ◽  
Vol 161 ◽  
pp. 437-442
Author(s):  
Salvatore Di Bernardo ◽  
Romana Fato ◽  
Giorgio Lenaz

AbstractOne of the peculiar aspects of living systems is the production and conservation of energy. This aspect is provided by specialized organelles, such as the mitochondria and chloroplasts, in developed living organisms. In primordial systems lacking specialized enzymatic complexes the energy supply was probably bound to the generation and maintenance of an asymmetric distribution of charged molecules in compartmentalized systems. On the basis of experimental evidence, we suggest that lipophilic quinones were involved in the generation of this asymmetrical distribution of charges through vectorial redox reactions across lipid membranes.


Author(s):  
Robert Corbett ◽  
Delbert E. Philpott ◽  
Sam Black

Observation of subtle or early signs of change in spaceflight induced alterations on living systems require precise methods of sampling. In-flight analysis would be preferable but constraints of time, equipment, personnel and cost dictate the necessity for prolonged storage before retrieval. Because of this, various tissues have been stored in fixatives and combinations of fixatives and observed at various time intervals. High pressure and the effect of buffer alone have also been tried.Of the various tissues embedded, muscle, cartilage and liver, liver has been the most extensively studied because it contains large numbers of organelles common to all tissues (Fig. 1).


1990 ◽  
Vol 45 (8) ◽  
pp. 980-981 ◽  
Author(s):  
Donald H. Ford

IEE Review ◽  
1992 ◽  
Vol 38 (2) ◽  
pp. 72
Author(s):  
K.K. Schwarz
Keyword(s):  

Author(s):  
Silvia PIZZOCARO ◽  
Pınar KAYGAN ◽  
HARMAN Kerry ◽  
Erik BOHEMIA

Co-design is a process in which designers and users collaborate as ‘equals’ to develop innovative solutions. Co-design methods are increasingly used by professional designers to facilitate and enable users to co-develop innovative solutions for ‘themselves’. For example, the Design Council is advocating the use of co-design methods to support the development of practical innovative solutions to social problems such as increased cost of elderly care and tackling child poverty. The involvement of users in developing solutions acknowledges that their take up is dependent on the ways users create and negotiate meanings of objects and services.


Author(s):  
Federico VAZ ◽  
Sharon PRENDEVILLE

Described as units developing public policies in a design-oriented manner, Policy Labs are tasked to innovate to gain in policy effectiveness and efficiency. However, as public policymaking is a context-dependent activity, the way in which these novel organisations operate significantly differs. This study discusses the emergence of design approaches for policy innovation. The purpose is to map how Policy Labs in Europe introduce design approaches at distinct stages of the policymaking cycle. For this study, 30 organisations in Europe operating at various levels of government were surveyed. Based on the public policymaking process model, it investigates which design methods are Policy Labs deploying to innovate public policies. The study exposed a gap in the awareness of the utilised methods' nature. It also showed that the use of design methods is of less importance than the introduction of design mindsets for public policy innovation, namely ‘user-centredness’, ‘co-creation’, and ‘exploration’.


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