scholarly journals Modifications of agar diffusion method to determination of the antimicrobial effect of the herbal medicinal products

2016 ◽  
Vol 0 (2(43)) ◽  
pp. 80-84
Author(s):  
N. M. Vorobets ◽  
H. V. Yavorska
Keyword(s):  
Antimicrobial Effect ◽  
Diffusion Method ◽  
Medicinal Products ◽  
Herbal Medicinal Products ◽  
Agar Diffusion ◽  
Herbal Medicinal ◽  
Agar Diffusion Method

scholarly journals Evaluation of the antimicrobial effect of calcium hydroxide combined to different vehicles

2016 ◽  
Vol 31 (2) ◽  
pp. 89
Author(s):  
Tatiana Dantas Piana ◽  
Maria de Fátima Malvar Gesteira ◽  
Erica Dos Santos Carvalho ◽  
Josilene Borges Torres Lima Matos ◽  
Monica Franca ◽  
...  
Keyword(s):  
Calcium Hydroxide ◽  
Enterococcus Faecalis ◽  
Antimicrobial Effect ◽  
Antimicrobial Action ◽  
Diffusion Method ◽  
Agar Diffusion ◽  
Inhibition Zones ◽  
Agar Diffusion Method

Objective: To evaluate the potentiating effect of different substances in antimicrobial action of calcium hydroxide.Methods: The agar diffusion method, was used with well technique, to analyze seven substances associated to calcium hydroxide to make some pastes, they are: chlorexidine, saline, anesthetic, malvatricin, propolis, hypochlorite, paramonochlorophenol.Results: The pastes with malvatricin and paramonochlorophenol presented greater inhibition zones against Enterococcus faecalis.Conclusion: There was potentialization in antimicrobial effect of calcium hydroxide when associated to paramonochlorophenol and to malvatricin especially against Enterococcus faecalis. Low increase of the antimicrobial capacity was observed when using chlorexidine as vehicle to calcium hydroxine paste.

scholarly journals Determination of the Marker Diarylheptanoid Phytoestrogens in Curcuma comosa Rhizomes and Selected Herbal Medicinal Products by HPLC-DAD

2018 ◽  
Vol 66 (1) ◽  
pp. 65-70 ◽  
Author(s):  
Bancha Yingngam ◽  
Adelheid Brantner ◽  
Damrongsak Jinarat ◽  
Rawiwun Kaewamatawong ◽  
Wandee Rungseevijitprapa ◽  
...  
Keyword(s):  
Medicinal Products ◽  
Curcuma Comosa ◽  
Herbal Medicinal Products ◽  
Herbal Medicinal

scholarly journals Comparative Evaluation of Assay Methods Used to Determine Anthracene Derivatives in Herbal Substances and Herbal Medicinal Products

2018 ◽  
Vol 8 (4) ◽  
pp. 252-261
Author(s):  
N. P. Antonova ◽  
I. M. Morgunov ◽  
S. S. Prokhvatilova ◽  
E. P. Shefer ◽  
A. M. Kalinin
Keyword(s):  
Experimental Studies ◽  
Total Content ◽  
Test Method ◽  
Theoretical Research ◽  
Medicinal Products ◽  
Herbal Medicinal Products ◽  
Anthracene Derivatives ◽  
Assay Methods ◽  
Herbal Medicinal

 The use of assay methods with different test conditions for determination of anthracene derivatives in herbal substances and herbal medicinal products requires adjustment of the established limits for total anthracene derivatives content based on the test method used.The aimof the study was to compare different pharmacopoeial methods of quantitative determination of anthracene derivatives, and established limits for the active substance content, and to analyse the possibility of adjusting the limits based on the test method used.Materials and methods: the total content of anthracene derivatives was measured in the samples of frangula bark (fragmented bark and powder) and senna leaves (fragmented leaves and powder) using the test methods described in the State Pharmacopoeia of the Russian Federation (XI and XIII editions), and the European Pharmacopoeia.Results:the analysis of Russian and foreign pharmacopoeial requirements for determination of anthracene derivatives in laxative herbal medicinal products demonstrated differences in extraction solvents, extraction conditions, and calculation methods used. The experiments showed that the optimal extraction solvent was 70 % alcohol solutions, and that an indirect cobaltic chloride reference standard should be replaced by specific absorbance of glucofrangulin A and sennoside B. It was shown that the limits for total anthracene derivatives content should be chosen based on the extraction conditions used.Conclusions:comparative theoretical research and experimental studies helped to determine optimal assay conditions and respective limits for total anthracene derivatives content to be used in quality control of herbal substances and herbal medicinal products.   

scholarly journals Determination of Anthracene Derivatives in Herbal Medicines

2021 ◽  
Vol 11 (2) ◽  
pp. 104-114
Author(s):  
O. V. Evdokimova ◽  
A. V. Beketova ◽  
M. N. Lyakina
Keyword(s):  
Comparative Analysis ◽  
Herbal Medicines ◽  
Quality Standards ◽  
Test Methods ◽  
Medicinal Products ◽  
Herbal Medicinal Products ◽  
Herbal Preparations ◽  
Anthracene Derivatives ◽  
Herbal Medicinal

The relevance of this study stems from the need for alignment of test methods used for identification and assay of anthracene derivatives in herbal preparations and herbal medicinal products. The aim of the study was to analyse Russian and international quality standards and to identify the most specific and sensitive test methods that could be used for herbal medicines containing anthracene derivatives. The comparative analysis of requirements in the Identification, Determination of major classes of bioactive compounds, and Assay parts of the Russian and foreign pharmacopoeial monographs for herbal preparations and herbal medicinal products containing anthracene derivatives, demonstrated that the main test method used for identification is thin layer chromatography, while assays most often rely on spectrophotometry. The so-called “consistent standardisation” principle is implemented in the Russian quality standards as regards alignment of methods used for anthracene derivative determination in herbal preparations (i.e. active pharmaceutical ingredients, APIs) and herbal medicinal products containing these APIs. The comparative analysis of requirements in the Russian and foreign quality standards for herbal medicines containing anthracene derivatives demonstrated the need for elaboration of two general chapters: Qualitative analysis of anthracene derivatives in herbal medicines and Quantitative analysis of anthracene derivatives in herbal medicines.

scholarly journals Limits for the Content of Heavy Metals and Arsenic as a Means of Ensuring Safe Use of Herbal Medicinal Products

2021 ◽  
Vol 9 (2) ◽  
pp. 61-68
Author(s):  
M. S. Galenko ◽  
I. V. Gravel ◽  
N. Yu. Velts ◽  
R. N. Alyautdin
Keyword(s):  
Heavy Metals ◽  
Human Body ◽  
Toxic Elements ◽  
Quantitative Methods ◽  
Arsenic Content ◽  
Medicinal Products ◽  
Herbal Medicinal Products ◽  
Herbal Medicinal ◽  
Heavy Metals And Arsenic

Herbal medicinal products (HMPs) are widely used in medical practice due to their availability, ease of use, and relatively safe pharmacological profile. However, medicinal plants are capable of accumulating heavy metals and arsenic which can have toxic effect on the human body when found in HMPs. The aim of the study was to summarise and analyse requirements of the Russian and foreign pharmacopoeias for the limits of heavy metals and arsenic in HMPs. National and regional pharmacopoeias have limits for the content of the major toxic elements (lead, cadmium, mercury, chromium, and arsenic) in HMPs. The study showed that the Indian and Japanese pharmacopoeias include only semi-quantitative methods for determination of heavy metals and arsenic, while the Russian and Chinese pharmacopoeias allow for the use of both quantitative and semi-quantitative methods. It was demonstrated that the limits for heavy metals and arsenic are the same for herbal substances and HMPs. The development of consistent approaches to determination of heavy metals and arsenic content, a systematic transition to quantitative methods of analysis, and establishment of individual limits for toxic elements in different HMP dosage forms, will make it possible to achieve the so-called consistent harmonisation, ensure reliable assessment of the content of heavy metals and arsenic, and minimize the risk of their entering human body with HMPs.

Determination of heavy metals in Ayurvedic herbal preparations by atomic emission spectrometry

2021 ◽  
pp. 62-65
Author(s):  
Margarita Dmitrievna Anikina ◽  
Yuliya Eduardovna Generalova ◽  
Irina Valerievna Gravel
Keyword(s):  
Heavy Metals ◽  
Atomic Emission ◽  
Atomic Emission Spectrometry ◽  
Emission Spectrometry ◽  
Qualitative And Quantitative Analysis ◽  
Medicinal Products ◽  
Herbal Medicinal Products ◽  
Qualitative And Quantitative ◽  
Herbal Medicinal

The article presents the results of a qualitative and quantitative analysis of the content of heavy metals in herbal medicinal products used in Ayurveda.

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