scholarly journals The Impact of Probiotics in Respiratory Diseases

2020 ◽  
Vol 10 (1) ◽  
pp. 148-156
Author(s):  
Rafee H. Askandar ◽  
Nasim Ebrahimi
Keyword(s):  
Tract Infection ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
The Other ◽  
Chronic Obstructive ◽  
Recurrent Respiratory Tract Infection ◽  
Other Hand ◽  
Probiotic Treatment ◽  
Wide Range ◽  
The Impact

Probiotics are viable microorganisms that, if adequately administered, confer great benefits to the host for the prevention or treatment of a wide range of human diseases, including recurrent respiratory tract infection (RRTI), cystic fibrosis, allergies, and chronic obstructive pulmonary disease (COPD). One of the current problems is that the overuse of antibiotics during respiratory tract infection has led to increased resistance to them, which has been demonstrated in numerous examinations that specific lactic acid bacteria (LAB), one of the key probiotics, against bacterial and viral infections of the respiratory and gastrointestinal tract, have a protective effect. On the other hand, changes in the gastrointestinal and respiratory microbiomes, especially lactobacilli and bifidobacteria, lead to an increase in allergies and asthma and a balance in the microbiome may improve symptoms. Probiotics are able to increase the number and activity of leukocytes, neutrophils, and NK cells. They can also increase IL-10 expression and decrease the expression of inflammatory cytokines such as TNF-α, IL-1β, and IL-8. In addition, they maintain high levels of IgA and produce bacteriocin and ruterin that have antimicrobial activity. Without identifying the specific properties of the probiotic strains and identifying the precise mechanism of their action, probiotic treatment would only be a large hypothesis because the therapeutic and clinical outcomes are different. On the other hand, metagenomics have provided information on how the microbiome interacts with host physiology, leading to new therapeutic targets.

scholarly journals COPD-Lower Respiratory Tract Infection Visual Analogue Score (c-LRTI-VAS) validation in stable and exacerbated patients with COPD

2021 ◽  
Vol 8 (1) ◽  
pp. e000761
Author(s):  
Hendrik Johannes Prins ◽  
Ruud Duijkers ◽  
Johannes M A Daniels ◽  
Thys van der Molen ◽  
Tjip S van der Werf ◽  
...  
Keyword(s):  
Tract Infection ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Lower Respiratory Tract Infection ◽  
Lower Respiratory Tract ◽  
Visual Analogue Score ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
Significant Difference ◽  
Related Quality

BackgroundWe developed the chronic obstructive pulmonary disease (COPD)-Lower Respiratory Tract Infection-Visual Analogue Score (c-LRTI-VAS) in order to easily quantify symptoms during exacerbations in patients with COPD. This study aimed to validate this score.MethodsIn our study, patients with stable COPD as well as those with an acute exacerbations of COPD (AECOPD) were included. The results of c-LRTI-VAS were compared with other markers of disease activity (lung function parameters, oxygen saturation and two health related quality of life questionnaires (St Georges Respiratory Questionnaire (SGRQ) and Clinical COPD Questionnaire (CCQ)) and validity, reliability and responsiveness were assessed.ResultsEighty-eight patients with clinically stable COPD and 102 patients who had an AECOPD completed the c-LRTI-VAS questionnaire. When testing on two separate occasions for repeatability, no statistically significant difference between total scores was found 0.143 (SD 5.42) (p=0.826). Internal consistency was high across items (Cronbach’s apha 0.755). Correlation with SGRQ and CCQ total scores was moderate to high. After treatment for hospitalised AECOPD, the mean c-LRTI-VAS total score improved 8.14 points (SD 9.13; p≤0.001).Conclusionsc-LRTI-VAS showed proper validity, responsiveness to change and moderate to high correlation with other questionnaires. It, therefore, appears a reliable tool for symptom measurement during AECOPD.Trial registration numberNCT01232140.

scholarly journals Recurrent respiratory tract infection or allergic rhinitis?

Alergoprofil ◽  
2019 ◽  
Vol 15 (1) ◽  
Author(s):  
Andrzej Emeryk ◽  
Justyna Emeryk-Maksymiuk ◽  
Arkadiusz Jędrzejewski
Keyword(s):  
Allergic Rhinitis ◽  
Tract Infection ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Recurrent Respiratory Tract Infection

To proceed or not to proceed: ENT surgery in paediatric patients with acute upper respiratory tract infection

2016 ◽  
Vol 130 (9) ◽  
pp. 800-804 ◽  
Author(s):  
S Shemesh ◽  
S Tamir ◽  
A Goldfarb ◽  
T Ezri ◽  
Y Roth
Keyword(s):  
Tract Infection ◽  
Literature Review ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Surgical Procedures ◽  
Upper Respiratory Tract Infection ◽  
Upper Respiratory Tract ◽  
Risk Benefit Assessment ◽  
Upper Respiratory ◽  
The Impact

AbstractBackground:Upper respiratory tract infection is the most common non-preventable cause of surgery cancellation. Consequently, surgeons and anaesthesiologists involved in elective ENT surgical procedures frequently face a dilemma of whether to proceed or to postpone surgery in affected children.Methods:A literature review was conducted and a practical assessment algorithm proposed.Conclusion:The risk–benefit assessment should take into consideration the impact of postponing the surgery intended to bring relief to the child and the risks of proceeding with general anaesthesia in an inflamed airway. The suggested algorithm for assessment may be a useful tool to support the decision of whether to proceed or to postpone surgery.

scholarly journals Recurrent Respiratory Tract Infection Caused by Moraxella catarrhalis in Patients with Pneumoconiosis

1999 ◽  
Vol 73 (4) ◽  
pp. 311-317 ◽  
Author(s):  
Akemi OMORI ◽  
Toshiaki YOSHIDA ◽  
Kana FURUKAWA ◽  
Atsushi TAKAHASHI ◽  
Syunichi MOCHINAGA ◽  
...  
Keyword(s):  
Tract Infection ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Moraxella Catarrhalis ◽  
Recurrent Respiratory Tract Infection

scholarly journals Recurrent Respiratory Tract Infection in an infant: Early Diagnosis by Clinical and Radiological Pearls

2021 ◽  
Vol 41 (1) ◽  
pp. 111-114
Author(s):  
Shatanik Sarkar ◽  
Chaitali Patra ◽  
Shibani Pal ◽  
Arkapriya Pramanik
Keyword(s):  
Tract Infection ◽  
Early Diagnosis ◽  
Respiratory Tract ◽  
Respiratory Tract Infection ◽  
Clinical Examination ◽  
Respiratory Tract Infections ◽  
Recurrent Respiratory Tract Infection ◽  
Organ Systems ◽  
Tract Infections ◽  
Recurrent Respiratory Tract Infections

Recurrent respiratory tract infections, a cause of concern for both parents and paediatricians, can have various etiologies entitled to different organ systems. Diagnosing the exact cause warrants both clinical acumen and timely investigations. Here, we are reporting an infant with recurrent respiratory tract infections, where adequate clinical examination prompted us to diagnose the extra-respiratory cause with simple investigations.

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