Hantavirus in the peruvian jungle: a systematic review of series and cases reported

Hantavirosis is a zoonotic infection transmitted mainly by rodents. In Peru, a lethality of 40–60% is calculated in inhabitants of the Peruvian Amazon jungle, especially in Loreto. Despite this, this disease continues to be under-diagnosed despite the fact that it represents a serious problem for public health in Latin America. We present a sistematic revision of case reports and seris of cases of Hantavirus infection in the Peruvian jungle. The most important characteristic of the cases presented are mean age 25.7 years, predominance of females (5/6), clinical presentation of headache, myalgias, nausea and vomiting (6/6) and unfavorable evolution to acute respiratory to acute respiratory distress (ARDS), renal failure, septic shock and multiple organ failure in 3of the cases presented.

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More than Pneumonia: Distinctive Features of SARS-Cov-2 Infection. From Autopsy Findings to Clinical Implications: A Systematic Review

Microorganisms ◽

10.3390/microorganisms8111642 ◽

2020 ◽

Vol 8 (11) ◽

pp. 1642

Author(s):

Stefano D’Errico ◽

Martina Zanon ◽

Martina Montanaro ◽

Davide Radaelli ◽

Francesco Sessa ◽

...

Keyword(s):

Systematic Review ◽

Case Reports ◽

Case Series ◽

Endothelial Damage ◽

Multiple Organ ◽

Post Mortem ◽

Letters To The Editor ◽

Distinctive Features ◽

First Results ◽

Inflammatory Processes

Despite safety recommendations for the management of corpses with COVID-19 infection and the high number of deaths worldwide, the post-mortem investigation rate is extremely low as well as the scientific contributions describing the pathological features. The first results of post-mortem investigations provided interesting findings and contributed to promoting unexplored therapeutic approaches and new frontiers of research. A systematic review is provided with the aim of summarizing all autopsy studies up to February 2020 in which a complete post-mortem investigation in patients with COVID-19 disease was performed, focusing on histopathological features. We included case reports, case series, retrospective and prospective studies, letters to the editor, and reviews. A total of 28 studies fulfilled the inclusion criteria, producing a pooled dataset of 407 full autopsies. Analyzing the medical history data, only 12 subjects had died without any comorbidities (for 15 cases the data were not available). The post-mortem investigation highlighted that acute respiratory distress syndrome (ARDS) and multiple organ failure represent the main clinical features of COVID-19 disease, often leading to pulmonary thromboembolism and superimposed bronchopneumonia. The discussed data showed a strict relationship among the inflammatory processes, diffuse alveolar, and endothelial damage. In light of these results, the full autopsy can be considered as the gold standard to investigate unknown infections or pathogens resulting in death.

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Hepatic Abscess Induced by Fish Bone Migration: Two Case Reports

Acta Médica Portuguesa ◽

10.20344/amp.9662 ◽

2018 ◽

Vol 31 (5) ◽

pp. 276 ◽

Cited By ~ 1

Author(s):

José Eduardo Mateus ◽

Carlos Silva ◽

Sofia Beirão ◽

Jorge Pimentel

Keyword(s):

Septic Shock ◽

Gastrointestinal Tract ◽

Foreign Bodies ◽

Clinical Presentation ◽

Case Reports ◽

Age Groups ◽

Hepatic Abscess ◽

Fish Bone ◽

Common Occurrence ◽

History Of

Although foreign body ingestion is a common occurrence, perforation and penetration of the gastrointestinal tract is unusual and the development of a hepatic abscess is even more rare. The authors describe two cases of fish bone perforation of the gastrointestinal tract with hepatic perforation and abscess formation, from distinctive age groups and varying presentation, although both developed septic shock. The lack of history of ingestion of foreign bodies, non-specificity of both clinical presentation and complementary examinations all play a role in delaying the diagnosis and therefore in the prognosis itself.

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Methylene blue for vasoplegic syndrome in cardiopulmonary bypass surgery: A systematic review and meta-analysis

Asian Cardiovascular and Thoracic Annals ◽

10.1177/0218492321998523 ◽

2021 ◽

pp. 021849232199852

Author(s):

Fajar Perdhana ◽

Nabila A Kloping ◽

Andro P Witarto ◽

David Nugraha ◽

Niwanda Yogiswara ◽

...

Keyword(s):

Systematic Review ◽

Methylene Blue ◽

Renal Failure ◽

Mortality Rate ◽

Multiple Organ Failure ◽

Organ Failure ◽

Unit Length ◽

Multiple Organ ◽

Morbidity Rate ◽

Vasoplegic Syndrome

Background To evaluate the benefit of methylene blue as an adjunct treatment by assessing hemodynamic, morbidity rate, intensive care unit length of stay, and mortality rate outcomes in adult patients with vasoplegic syndrome. Methods A systematic search through electronic databases including Pubmed, Embase, Scopus, and Medline for studies assessing the use of methylene blue in patients with vasoplegic syndrome compared to control treatments. The Newcastle–Ottawa Scale tool was used for observational studies, and Jadad Scale was used for controlled trials to assess the risk of bias. Results This systematic review included six studies for qualitative synthesis and five studies for quantitative synthesis. Pooled analysis revealed that mean arterial pressure, systemic vascular resistance, heart rate, and hospital stay were not statistically significant in methylene blue administration compared to control. However, administration of methylene blue in vasoplegic syndrome patients significantly reduces renal failure (OR = 0.25; 95% CI = 0.08–0.75), development of multiple organ failure (OR = 0.09; 95% CI = 0.02–0.51), and mortality rate (OR = 0.12; 95% CI = 0.03–0.46). Conclusion Adjunct administration of methylene blue for vasoplegic syndrome patients significantly reduces renal failure, multiple organ failure, and mortality.

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Recurrent SARS-CoV-2 infections and their potential risk to public health – a systematic review

PLoS ONE ◽

10.1371/journal.pone.0261221 ◽

2021 ◽

Vol 16 (12) ◽

pp. e0261221

Author(s):

Seth Kofi Abrokwa ◽

Sophie Alice Müller ◽

Alba Méndez-Brito ◽

Johanna Hanefeld ◽

Charbel El Bcheraoui

Keyword(s):

Public Health ◽

Systematic Review ◽

Recurrence Rate ◽

Potential Risk ◽

Observational Studies ◽

Case Reports ◽

Relevant Literature ◽

Contact Tracing ◽

Epidemiological Characteristics

Objective To inform quarantine and contact-tracing policies concerning re-positive cases—cases testing positive among those recovered. Materials and methods We systematically reviewed and appraised relevant literature from PubMed and Embase for the extent of re-positive cases and their epidemiological characteristics. Results In 90 case reports/series, a total of 276 re-positive cases were found. Among confirmed reinfections, 50% occurred within 90 days from recovery. Four reports related onward transmission. In thirty-five observational studies, rate of re-positives ranged from zero to 50% with no onward transmissions reported. In eight reviews, pooled recurrence rate ranged from 12% to 17.7%. Probability of re-positive increased with several factors. Conclusion Recurrence of a positive SARS-CoV-2 test is commonly reported within the first weeks following recovery from a first infection.

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The impact of the COVID-19 pandemic on self-harm and suicidal behaviour: protocol for a living systematic review

F1000Research ◽

10.12688/f1000research.24274.1 ◽

2020 ◽

Vol 9 ◽

pp. 644 ◽

Cited By ~ 3

Author(s):

Ann John ◽

Emily Eyles ◽

Luke A. McGuinness ◽

Chukwudi Okolie ◽

Babatunde K. Olorisade ◽

...

Keyword(s):

Public Health ◽

Systematic Review ◽

Suicidal Behaviour ◽

Research Evidence ◽

Single Case ◽

Case Reports ◽

Eligibility Criteria ◽

Protection Measures ◽

Self Harm ◽

The Impact

Background: The COVID-19 pandemic has caused widespread morbidity and mortality as well as disruption to people’s lives and livelihoods around the world; this has occurred as a result of both infection with the virus itself and the health protection measures taken to curb its spread. There are concerns that rates of suicide, suicidal behaviours and self-harm may rise during and in the aftermath of the pandemic. Given the likely rapidly expanding research evidence base on the pandemic’s impact on rates of suicide, suicidal behaviours and self-harm and emerging evidence about how best to mitigate such effects, it is important that the best available knowledge is made readily available to policymakers, public health specialists and clinicians as soon as is possible. To facilitate this, we plan to undertake a living systematic review focusing on suicide prevention in relation to COVID-19. Method: Regular automated searches will feed into a web-based screening system which will also host the data extraction form for included articles. Our eligibility criteria are wide and include aspects of incidence and prevalence of suicidal behaviour, effects of exposures and effects of interventions in relation to the COVID-19 pandemic, with minimal restrictions on the types of study design to be included. The outcomes assessed will be death by suicide; self-harm or attempted suicide (including hospital attendance and/or admission for these reasons); and suicidal thoughts/ideation. There will be no restriction on study type, except for single case reports. There will be no restriction on language of publication. The review will be updated at three-monthly intervals if a sufficient volume of new evidence justifies doing so. Conclusions: Our living review will provide a regular synthesis of the most up-to-date research evidence to guide public health and clinical policy to mitigate the impact of COVID-19 on suicide. Protocol registration: PROSPERO CRD42020183326 01/05/2020

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Internal mammary artery-to-pulmonary vasculature fistula: Systematic review of case reports

Vascular Medicine ◽

10.1177/1358863x17724262 ◽

2017 ◽

Vol 22 (5) ◽

pp. 426-431 ◽

Cited By ~ 5

Author(s):

Ali Abdul Jabbar ◽

Amish Patel ◽

Nathan Marzlin ◽

Sayf Altabaqchali ◽

Mohanad Hasan ◽

...

Keyword(s):

Systematic Review ◽

Internal Mammary Artery ◽

Clinical Presentation ◽

Case Reports ◽

Artery Bypass ◽

Pulmonary Vasculature ◽

Bypass Grafting ◽

Chronic Infections ◽

Inflammatory Conditions ◽

Internal Mammary

The formation of a fistula between the internal mammary artery and the pulmonary vasculature (IMA-to-PV) is a rare anomaly. The etiology can be congenital; however, most recent cases have been associated with coronary artery bypass grafting, trauma, inflammatory conditions, chronic infections, or neoplasia. The knowledge base on the formation of these fistulas is derived primarily from case reports. To our knowledge, no systematic reviews or guidelines are available that provide information on how to manage these cases, and the treatment of an IMA-to-PV fistula is controversial. To our knowledge, this report is the first to review 80 cases of IMA-to-PV fistulas reported in the literature. We describe the etiologies, clinical presentation, and management of these fistulas.

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Cannabis-associated arteritis

VASA ◽

10.1024/0301-1526/a000004 ◽

2010 ◽

Vol 39 (1) ◽

pp. 43-53 ◽

Cited By ~ 17

Author(s):

Grotenhermen

Keyword(s):

Systematic Review ◽

Case Reports ◽

Case Series ◽

Cardiovascular Effects ◽

Causative Factor ◽

Cannabis Use ◽

Thromboangiitis Obliterans ◽

Pathological Features ◽

Scientific Support ◽

Clinical And Pathological Features

Background: To investigate the hypothesis that cases of arteritis similar to thromboangiitis obliterans (TAO) and associated with the use of cannabis were caused by cannabis or THC (dronabinol), or that cannabis use is a co-factor of TAO. Patients and methods: A systematic review on case reports and the literature on so-called cannabis arteritis, TAO, and cardiovascular effects of cannabinoids was conducted. Results: Fifteen reports with 57 cases of an arteritis associated with the use of cannabis and two additional case series of TAO, in which some patients also used cannabis, were identified. Clinical and pathological features of cannabis-associated arteritis do not differ from TAO and the major risk factor of TAO, tobacco use, was present in most, if not in all of these cases. The proposed pathophysiological mechanisms for the development of an arteritis by cannabis use are not substantiated. Conclusions: The hypothesis of cannabis being a causative factor or co-factor of TAO or an arteritis similar to TAO is not supported by the available evidence. The use of the term cannabis arteritis should be avoided until or unless more convincing scientific support is forthcoming.

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