scholarly journals Impact of Comorbidities on Self-Esteem of Children with Attention Deficit Hyperactivity Disorder

2016 ◽  
Vol 3 (3) ◽  
Author(s):  
Pradeep Palaniappan

Background: 2 decades of research had found that comorbid disorders occur in children with ADHD more than by chance. The role of comorbidities in influencing the self-esteem of children with ADHD is still less explored. Aims: To study the various domains of self-esteem in children with ADHD and to evaluate the effect of comorbidities on low self-esteem in ADHD children. Methods And Materials: 60 subjects aged 6 to 16 years who were diagnosed based on DSM IV as ADHD were recruited with informed consent, from tertiary care hospital for a period of 6 months by consecutive sampling. Based on detailed interview of subjects and parents using the Semi structured assessment schedule K- SADS – PL for comorbidities, children with ADHD were grouped as those with and without comorbidities. While severity of ADHD was assessed by Conner’s Parent’s 10 item abbreviated index, self-esteem was assessed by Culture free self-esteem inventory. Results: Parent related self-esteem was lower in ADHD children with comorbid internalizing disorders when compared to ADHD children with comorbid externalizing disorders. Higher severity of ADHD and longer duration of ADHD correlated with lower self-esteem, (especially social domain). Conclusions: Comorbidities definitely influence the level of self-esteem in children with ADHD, but other factors also need to be considered for optimal management of low self-esteem.

Author(s):  
Vinod Kumar ◽  
Bhupen Songra ◽  
Richa Jain ◽  
Deeksha Mehta

Background: the present study was under taken to determine the role of CA-125 in the diagnosis of acute appendicitis (AA), to prevent its complications and also in preventing negative appendicectomies in tertiary care hospital. Methods: The study was conducted at a tertiary care and research center between 01/03/2018 to 30/06/2019. Patients admitted to the surgery department with diagnosis of AA were considered for the study. After informed consent, a, standardized history was obtained as a case Performa. Serum samples from all the cases with clinical diagnosis of AA were obtained and stored. Only the cases with histopathologically approved AA were included in the study. Cases operated for clinical diagnosis of AA, but not histopathologically proven AA was not included in the study. CA125 levels in cases with definitive diagnosis of AA were measured. Results: In present study, ROC curve analysis revealed the sensitivity of 87.27 % and specificity of 90.91 % when the CA 125 cut-off value of > 16.8 was taken to diagnose acute appendicitis. AUC was 0.911 with a standard error of 0.0292. Conclusion: In this study we have observed that CA125 showed a positive correlation with acute appendicitis, that was statistically not significant (P>0.05). We didn’t evaluate the correlation with the disease severity. We consider that CA125 can be used as a marker in acute appendicitis cases although further research is still needed. Keywords: CA125, Acute Appendicitis, Surgery.


2017 ◽  
Vol 6 (94) ◽  
pp. 6858-6862
Author(s):  
Singhal R P ◽  
Pardaman Singh Setia ◽  
Kawal Preet Kaur ◽  
Virinder Mohan ◽  
Payal Bansal

2020 ◽  
Vol 8 (1) ◽  
pp. 4-6
Author(s):  
Ashu Dogra

Porphyria cutanea tarda is the most frequent type of Porphyria worldwide & presents with skin symptoms mainly. Porphyrias can affect peripheral, autonomic and central nervous system. In Porphyria conditions there is accumulation of heme precursors 5 Aminolevulinic acid, Porphobilinogen and porphyrins which are associated with characteristic clinical feature with acute neurovisceral attacks and skin lesions. This case report summarizes Case of PCT that was successfully managed with Therapeutic Phlebotomy.


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