Seasonal variation of vitamin D levels, calcium and other markers of bone metabolism in HIV infected patients

2016 ◽  
Author(s):  
Sebastian Noe
Keyword(s):  
Vitamin D ◽  
Seasonal Variation ◽  
Bone Metabolism ◽  
Vitamin D Levels

25-Hydroxyvitamin D levels in serum at the onset of multiple sclerosis

2005 ◽  
Vol 11 (3) ◽  
pp. 266-271 ◽  
Author(s):  
M Soilu-Hänninen ◽  
L Airas ◽  
I Mononen ◽  
A Heikkilä ◽  
M Viljanen ◽  
...  
Keyword(s):  
Vitamin D ◽  
Bone Metabolism ◽  
Sun Exposure ◽  
Serum Levels ◽  
Vitamin D Supplementation ◽  
Hydroxyvitamin D ◽  
Normal Bone ◽  
Vitamin D Levels ◽  
25 Hydroxyvitamin D ◽  
Lower Vitamin

Past sun exposure and vitamin D supplementation have been associated with a reduction in the risk of MS. We measured the serum concentration of 25-hydroxyvitamin D (25[OH]D) at the time of MS diagnosis in 40 MS patients and 40 controls. We found no difference in the serum levels of 25(OH)D between MS patients and controls when all samples or samples obtained during winter months were compared, but MS patients had significantly lower serum 25(OH)D concentrations in June to September than the controls. The vitamin D stores were adequate for bone metabolism (> 37 nmol/L) in 70% of MS patients throughout the year and within the hypovitaminosis level (< 37 nmol/L) in 30% of MS patients at some time of the year. During MS-relapses, 25(OH)D levels were lower than in remission, but mostly within the reference range observed in relation with normal bone metabolism. We conclude that the vitamin D stores in most MS patients are adequate for their normal bone metabolism. However, lower vitamin D levels during MS relapses than in remission suggest that vitamin D could be involved in the regulation of the clinical disease activity of MS. The optimal serum levels of vitamin D for the regulation of immune responses remain to be determined.

Reversed Seasonal Variation in Maternal Vitamin D Levels in Southern Louisiana

2012 ◽  
Vol 51 (8) ◽  
pp. 718-722 ◽  
Author(s):  
Mariam Gangat ◽  
Tulasi Ponnapakkam ◽  
Elease Bradford ◽  
Ranjitha Katikaneni ◽  
Robert Gensure
Keyword(s):  
Vitamin D ◽  
Seasonal Variation ◽  
Maternal Vitamin ◽  
Vitamin D Levels ◽  
Southern Louisiana

Serum 25(OH)-vitamin D levels and bone metabolism in patients on maintenance hemodialysis

2005 ◽  
Vol 64 (10) ◽  
pp. 288-294 ◽  
Author(s):  
I. Mucsi ◽  
C. Almási ◽  
G. Deák ◽  
A. Marton ◽  
C. Ambrus ◽  
...  
Keyword(s):  
Vitamin D ◽  
Bone Metabolism ◽  
Maintenance Hemodialysis ◽  
Vitamin D Levels ◽  
25 Oh Vitamin D

scholarly journals Correlation between markers of bone metabolism and vitamin D levels in patients with monoclonal gammopathy of undetermined significance (MGUS)

2017 ◽  
Vol 7 (12) ◽  
Author(s):  
Brea Lipe ◽  
Suman Kambhampati ◽  
Peter Van Veldhuizen ◽  
Abdulraheem Yacoub ◽  
Omar Aljitawi ◽  
...  
Keyword(s):  
Vitamin D ◽  
Bone Metabolism ◽  
Monoclonal Gammopathy ◽  
Vitamin D Levels ◽  
Undetermined Significance

scholarly journals Bone Metabolism In Patients With Type 1 Neurofibromatosis: Key Role of Sun Exposure and Physical Activity

2021 ◽  
Author(s):  
Ursula Pia Ferrara ◽  
Cristina Tortora ◽  
Carmen Rosano BD ◽  
Antonia Assunto BD ◽  
Alessandro Rossi ◽  
...  
Keyword(s):  
Physical Activity ◽  
Vitamin D ◽  
Bone Metabolism ◽  
Bone Mineral ◽  
Linear Regression Analysis ◽  
Serum Vitamin ◽  
Sun Exposure ◽  
Mineral Density ◽  
Vitamin D Levels ◽  
Cholecalciferol Supplementation

Abstract Bone metabolism has been rarely investigated in children affected by Neurofibromatosis (NF1). Aim of the present study was to assess bone mineral metabolism in children and adults NF1 patients, to determine the relevant factors potentially involved in the development of reduced bone mineral density (BMD), and provide possible therapeutic intervention in NF1 patients. 114 NF1 patients and sex and age matched controls were enrolled into the study. Clinical and biochemical factors reflecting bone metabolism were evaluated. Factors potentially affecting BMD were also investigated including: physical activity, sun exposure, vitamin D intake. Whenever the presence of vitamin D deficiency was recorded, cholecalciferol supplementation was started and BMD data obtained during supplementation were compared with previous ones. NF1 patients showed lower Z-scores at Dual-Energy X-ray Absorptiometry (DXA) than controls. Physical activity was significantly reduced in NF1 patients than in controls. Sun exposure was significantly lower in NF1 compared to control subjects. At linear regression analysis vitamin D was the most predictive factor of reduced BMD (p = 0.0001). Cholecalciferol supplementation significantly increased BMD z.score (p = 0.000). We speculated that a combination of different factors, including reduced sun exposure, possibly associated with reduced serum vitamin D levels, and poor physical activity, concur to the impaired bone status in NF1 patients. We also demonstrated that treatment with vitamin D can be effective in improving BMD in NF1 patients, including children. In conclusion, the findings of the current study are expected to have important implications for the follow-up and prevention of osteopenia/osteoporosis in this common genetic disease.

scholarly journals Vitamin D Daily versus Monthly Administration: Bone Turnover and Adipose Tissue Influences

Nutrients ◽  
2018 ◽  
Vol 10 (12) ◽  
pp. 1934 ◽  
Author(s):  
Luca Dalle Carbonare ◽  
Maria Valenti ◽  
Francesco del Forno ◽  
Giorgio Piacentini ◽  
Angelo Pietrobelli
Keyword(s):  
Vitamin D ◽  
Waist Circumference ◽  
Bone Turnover ◽  
Bone Metabolism ◽  
Vitamin D3 ◽  
Metabolic Diseases ◽  
Neurological Diseases ◽  
Protective Role ◽  
Vitamin D Levels ◽  
Monthly Administration

Vitamin D is involved in bone metabolism and in many various extra-skeletal diseases such as malabsorption syndromes, cardiovascular and metabolic diseases, cancer, and autoimmune and neurological diseases. However, data on the optimal route of administration are not consistent. The aims of our study were to analyze not only the influence of daily vs. monthly administration of vitamin D on bone metabolism and bone turnover, but also the effects of different routes of administration on fat mass in a cohort of adults with low levels of 25(OH) vitamin D3 at baseline. We analyzed 44 patients with hypovitaminosis at baseline and after six months of two different regimens of administration: seven drops (1750 IU)/day vs. 50,000 IU/month. We found that the two regimens were equivalent; 36 out of 44 patients reached the normal range of vitamin D after six months of treatment. Interestingly, the main determinant of vitamin D at baseline was the waist circumference. In addition, 22 patients treated by monthly regimen were evaluated after 18 months of treatment. At the end of follow-up, patients showed normal levels of vitamin D, with increased calcium levels and decreased bone turnover. Waist circumference also decreased. Our results support the efficacy of vitamin D3 given monthly both for correcting hypovitaminosis and for maintaining vitamin D levels. The relationship between serum 25(OH)vitamin D3 concentration and waist circumference supports vitamin D having a protective role in the current setting, since waist size is directly associated with the risk of cardiovascular and metabolic diseases.

scholarly journals Vitamin D Status and Its Determinants in a Paediatric Population in Norway

Nutrients ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 1385
Author(s):  
Mads N Holten-Andersen ◽  
Johanne Haugen ◽  
Ingvild Oma ◽  
Tor A Strand
Keyword(s):  
Vitamin D ◽  
Seasonal Variation ◽  
Children And Adolescents ◽  
Parental Education ◽  
Sun Exposure ◽  
Late Summer ◽  
Paediatric Population ◽  
Vitamin D Supplementation ◽  
Healthy Children ◽  
Vitamin D Levels

Recommendations for sufficient vitamin D intake in children were recently revised in Norway. However, optimal levels of vitamin D are still debated and knowledge on supplementation and vitamin D levels in healthy children in Norway is scarce. Therefore, we measured the plasma-concentration of 25-hydroxyvitamin D (25(OH)D) in children and adolescents attending the outpatient paediatric clinics in Innlandet Hospital Trust, Norway during two consecutive years (2015–2017). We recruited 301 children and adolescents aged 5 months to 18 years (mean 7.8, SD 4.4 years) for the study and obtained sample material for 25(OH)D measurements from 295 (98%). Information on diet, vitamin D supplementation, sun exposure, ethnicity, parental education and general health was collected by questionnaire. 25(OH)D levels were analysed and determinants for 25(OH)D were estimated by linear regression. 1.0% of the children had deficient levels (25(OH)D < 25 nmol/L) and 21.0% had insufficient levels (25–50 nmol/L). 25(OH)D levels ranging from 50 to 75 nmol/L were found among 38.3%, while 39.7% had levels above 75 nmol/L. The mean 25(OH)D level was 70.0 nmol/L (SD 23.4, range 17–142 nmol/L) with a significant seasonal variation with lowest levels in mid-winter and highest in late summer. In addition to seasonal variation independent determinants for 25(OH)D-levels were age of the child, parental ethnicity, vitamin D supplementation and soda consumption. Along with parental ethnicity other than Nordic, age was the strongest determinant of 25(OH)D, with adolescents having the lowest levels.

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