Long-term effectiveness of fingolimod in multiple sclerosis patients treated in the routine care of Greece: Results of the ‘DIAMOND’ non-interventional, prospective, observational study

Author(s):  
Dimos Dimitrios Mitsikostas
2010 ◽  
Vol 16 (10) ◽  
pp. 1248-1251 ◽  
Author(s):  
S. Sotgiu ◽  
G. Mameli ◽  
C. Serra ◽  
IR Zarbo ◽  
G. Arru ◽  
...  

Retrovirus-like particles containing the multiple sclerosis-associated retrovirus RNA, significantly found in the cerebrospinal fluid of patients with multiple sclerosis, have been preliminarily associated with a short-term poor clinical and radiological prognosis of the disease. We asked whether these prognostic indications are still measurable after a long-term clinical evaluation (10 years). Our 10-year blind observational study confirms that the presence of multiple sclerosis-associated retrovirus in the cerebrospinal fluid of early multiple sclerosis patients is associated with a significantly greater rate of relapse-unrelated unremitting disability and secondary progression of the disease.


Author(s):  
Francesca Corzani ◽  
Carolina Cecchetti ◽  
Claudia Oriolo ◽  
Paola Altieri ◽  
Annamaria Perri ◽  
...  

2020 ◽  
Vol 11 ◽  
Author(s):  
Justin M. Honce ◽  
Kavita V. Nair ◽  
Brian D. Hoyt ◽  
Rebecca A. Seale ◽  
Stefan Sillau ◽  
...  

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