Graphene-Oxide Based Fluorescent DNA Aptasensor for Liver Cancer Diagnosis and Therapy
Keyword(s):
Graphene-oxide based fluorescent DNA aptasensors for the <i>in vivo </i>application remain a challenging task. We demonstrate for the first time such a nanomaterial for <i>in vivo</i> diagnosis and therapy of liver tumor with good biocompatibility and high selectivity. This DNA nanomaterial comprising of DNA tetrahedron and aptamers, aggregation-induced emission luminogen (AIEgens) and antitumor drug doxorubicin, is fabricated and attached on GO surface. Additionally, this GO-based fluorescent DNA nanodevice is also constructed by using microfluidic chip for liver tumor cell screening.
2021 ◽
2014 ◽
Vol 8
(7)
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pp. 389-395
Keyword(s):
2018 ◽
Vol 19
(11)
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pp. 3564
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2015 ◽
Vol 493
(1-2)
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pp. 313-327
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2017 ◽
Vol 2017
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pp. 1-11
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2009 ◽
Vol 26
(3)
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pp. 207-273
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