Shedding Light on Graphene Quantum Dots: Key Synthetic Strategies, Characterization Tools, and Cutting-Edge Applications

During the last 20 years, the scientific community has shown growing interest towards carbonaceous nanomaterials due to their appealing mechanical, thermal, and optical features, depending on the specific nanoforms. Among these, graphene quantum dots (GQDs) recently emerged as one of the most promising nanomaterials due to their outstanding electrical properties, chemical stability, and intense and tunable photoluminescence, as it is witnessed by a booming number of reported applications, ranging from the biological field to the photovoltaic market. To date, a plethora of synthetic protocols have been investigated to modulate the portfolio of features that GQDs possess and to facilitate the use of these materials for target applications. Considering the number of publications and the rapid evolution of this flourishing field of research, this review aims at providing a broad overview of the most widely established synthetic protocols and offering a detailed review of some specific applications that are attracting researchers’ interest.

Adult Education at Biological Field Stations: Building Capacity for Science Learning

An understanding of science concepts is important for living in modern society. Supporting adults’ science learning can be particularly challenging because most adults no longer attend formal educational institutions where access and opportunities are facilitated by teachers and school-sponsored programs. Biological field stations (BFSs) are a newly recognized educational venue that hold considerable intrinsic value for adult science education. In this study, we conducted a survey of 223 U.S. BFSs about their nonformal and informal educational outreach programs for adults. Results show BFSs offer a wide variety of science learning programs for adults, focused heavily on experiential learning to engage learners. These experiences promote interactions with the natural environment and are perceived to increase participants’ knowledge and skills. This study has implications for how adult educators can better support the professional development of science educators at BFSs and enrich the general public's science learning.

Recent advances in the syntheses of anthracene derivatives

Anthracene and anthracene derivatives have been extensively studied over the years because of their interesting photophysical, photochemical, and biological properties. They are currently the subject of research in several areas, which investigate their use in the biological field and their application in OLEDs, OFETs, polymeric materials, solar cells, and many other organic materials. Their synthesis remains challenging, but some important preparative methods have been reported, especially in the last decade. This review presents an update of the recent strategies that have been employed to prepare anthracene derivatives. It encompasses papers published over the last twelve years (2008–2020) and focuses on direct and indirect methods to construct anthracene and anthraquinone frameworks.

Carbon Dots as Promising Tools for Cancer Diagnosis and Therapy

Carbon Dots (CDs) are the latest members of carbon-based nanomaterials, which since their discovery have attracted notable attention due to their chemical and mechanical properties, brilliant fluorescence, high photostability, and good biocompatibility. Together with the ease and affordable preparation costs, these intrinsic features make CDs the most promising nanomaterials for multiple applications in the biological field, such as bioimaging, biotherapy, and gene/drug delivery. This review will illustrate the most recent applications of CDs in the biomedical field, focusing on their biocompatibility, fluorescence, low cytotoxicity, cellular uptake, and theranostic properties to highlight above all their usefulness as a promising tool for cancer diagnosis and therapy.

Repurposing of Drugs Targeted Against COVID-19 Spike Receptor for Treatment: An In silico Approach

An escalating pandemic by the novel SARS-CoV2 is spreading across the globe at a rate. An urgent need for therapy is needed. Initially, the virus appeared first in Wuhan, China, and later approximately in 187 countries worldwide. Coronaviruses are causative of respiratory as well as neurological diseases in humans. The novel zoonotic disease-causing coronaviruses are single-stranded RNA viruses. The coronavirus's outer structure consists of spike protein made up of glycoproteins, which binds to ACE (Angiotensin Converting Enzyme) protein when infected in humans. In the current study, 37 compounds that are already used in the biological field as anti-viral compounds are observed with bioinformatics tools. The repurposing drugs are docked against the spike receptor by molecular Docking. The ligand structure and the receptor structure are retrieved from Protein Data Bank. Patch dock server is an open freeware available for docking procedures. The results include acceleration and score of matched properties showing the feasibility of working the drug against SARS-nCoV. For the visualization of the final docked product, PyMOL and RasWin software’s are used. The scores of each ligand docked against the receptor show the compatibility working against the COVID-19 disease.

Physiology and Physical Chemistry of Bile Acids

Bile acids (BAs) are facial amphiphiles synthesized in the body of all vertebrates. They undergo the enterohepatic circulation: they are produced in the liver, stored in the gallbladder, released in the intestine, taken into the bloodstream and lastly re-absorbed in the liver. During this pathway, BAs are modified in their molecular structure by the action of enzymes and bacteria. Such transformations allow them to acquire the chemical–physical properties needed for fulling several activities including metabolic regulation, antimicrobial functions and solubilization of lipids in digestion. The versatility of BAs in the physiological functions has inspired their use in many bio-applications, making them important tools for active molecule delivery, metabolic disease treatments and emulsification processes in food and drug industries. Moreover, moving over the borders of the biological field, BAs have been largely investigated as building blocks for the construction of supramolecular aggregates having peculiar structural, mechanical, chemical and optical properties. The review starts with a biological analysis of the BAs functions before progressively switching to a general overview of BAs in pharmacology and medicine applications. Lastly the focus moves to the BAs use in material science.

MAKNA KATA DALAM BIDANG STRUKTUR BANGUNAN YANG BERASOSIASI DENGAN BIDANG BIOLOGIS

This research is entitled, "The Meaning of Words in the Field of Building Structures Associated with the Biological Field". This study aims to analyze the meaning of various terms, in particular, words in the field of building structures that contain biological elements. Researchers used descriptive qualitative methods. Data collection was done by observing method and note taking technique. The data in this study are in the form of a list of terms contained in the SNI for loading and SNI for reinforced concrete. The theory of semantic studies regarding the shift in meaning, especially associative meaning, becomes the theory used in research. The results show that in the field of civil engineering there are the same words as elements of the term biological. Some of the associated words include diaphragm, reinforcement, and tendons. These three words are used because of developments in science and technology, differences in usage, and development of terms. These three factors are caused by the need to use terms in the field of civil engineering which contain elements of similarity in nature to biological elements