scholarly journals The study of vascular wall stiffness in patients with arterial hypertension depending on some factors of risk and associated clinical conditions

2019 ◽  
Vol 10 (1) ◽  
pp. 6-11
Author(s):  
Larisa A. Khaisheva ◽  
Sergey V. Shlyk ◽  
Azat S. Samakaev ◽  
Svetlana E. Glova ◽  
Anna A. Pirozhenko ◽  
...  
Keyword(s):  
Arterial Hypertension ◽  
Propagation Velocity ◽  
Pulse Wave ◽  
Classical Method ◽  
Vascular Wall ◽  
Functional Class ◽  
Wall Stiffness ◽  
History Of ◽  
Stage 1 ◽  
Clinical Conditions

Aim. To study the effect of gender, age, duration of disease and different forms of ischemic heart disease on the stiffness of the vascular wall in patients with arterial hypertension by determining the propagation velocity of the pulse wave. Materials and methods. In order to study the propagation velocity of the pulse wave it was examined 369 patients with the method of volumetric sphygmography. In all patients was diagnosed arterial hypertension I-III stage, 1-3 degree, besides 47 patients were diagnosed with stable angina I-III functional class, 50 patients had a history of prior myocardial infarction. The investigation was held with the help of hardware complex "Poli-Spektr" made by Neirosoft firm (city Ivanovo) by the classical method of determining the propagation velocity of the pulse wave using synchronous registration sphygmograms of the carotid, radial and femoral arteries. Results. Patients with arterial hypertension had statistically higher velocity of pulse wave propagation for elastic-type vessels in comparison with healthy volunteers (9.48±0.18 и 7.28±0.64 cm/sec; р

Assessment of arterial wall stiffness by 24-hour blood pressure monitoring

2016 ◽  
Vol 88 (9) ◽  
pp. 119-124 ◽  
Author(s):  
V A Korneva ◽  
T Yu Kuznetsova
Keyword(s):  
Blood Pressure ◽  
Arterial Wall ◽  
Pulse Wave ◽  
Blood Pressure Monitoring ◽  
Vascular Wall ◽  
Pressure Monitoring ◽  
Therapeutic Practice ◽  
Wall Stiffness ◽  
The Given ◽  
Large Vessels

Arterial wall stiffness is an early marker of cardiovascular diseases. The gold standard for assessment of the stiffness of large vessels is presently pulse wave velocity (PWV). Work is in progress on the study of the reference values of PWV in people of different genders and ages. 24-hour blood pressure (BP) monitoring is not only a procedure that can estimate diurnal BP variability, but also monitor the indicators of vascular wall stiffness in a number of cases over a 24-hour period. The given review highlights the pathophysiology of arterial stiffness, methods for its assessment, and the aspects of use in therapeutic practice.

scholarly journals The increasing of arterial vascular resistance is a primary factor of development isolated systolic hypertensions

2007 ◽  
Vol 13 (1) ◽  
pp. 7-13
Author(s):  
A. A. Sokolov ◽  
M. V. Soldatenko
Keyword(s):  
Arterial Stiffness ◽  
Pulse Wave Velocity ◽  
Arterial Hypertension ◽  
Vascular Resistance ◽  
Vascular Tone ◽  
Arterial Wall ◽  
Pulse Wave ◽  
Vascular Wall ◽  
Non Invasive ◽  
Modern Methods

In the submitted review value of increase of vascular resistance and a vascular tone in development of an isolated arterial hypertension has been shown. Parameters of elasticity of the arteries, used for the characteristic of properties of a vascular wall are discussed. In the review modern methods non invasive study of the properties of the arterial wall was described. The special attention has been given study of the pulse wave velocity, value of parameters of resistance and arterial stiffness for an estimation of the forecast was shown.

scholarly journals BENEFITS OF VOLUMETRIC COMPRESSION OSCILLOMETRY FOR THE ASSESSMENT OF HEMODYNAMIC PARAMETERS IN PATIENTS WITH ARTERIAL HYPERTENSION

2013 ◽  
Vol 12 (2) ◽  
pp. 10-17
Author(s):  
L. V. Shpak ◽  
E. S. Galoshina
Keyword(s):  
Arterial Hypertension ◽  
Vascular Wall ◽  
Healthy People ◽  
Control Group ◽  
Hemodynamic Parameters ◽  
Simultaneous Reduction ◽  
Non Invasive ◽  
Wide Range ◽  
The Status ◽  
Stage 1

Aim. To compare the parameters of central and peripheral hemodynamics in healthy people and patients with Stage 1–3 arterial hypertension (AH).Material and methods. In total, 105 individuals were examined. The control group (CG) included 50 healthy people (25 women and 25 men; mean age 27,8±0,8 years) with optimal and normal levels of blood pressure (BP) (mean levels 118,5±1,6/71,82±1,2 mm Hg). The main group (MG) included 55 patients (41 women and 14 men; mean age 62,9±1,6 years) with systolo-diastolic AH: Stage 1 in 25 (mean BP levels 146,1±0,9/84,9±1,6 mm Hg), Stage 2 in 20 (164,4±1,8/95±2,1 mm Hg), and Stage 3 in 10 (189,6±10,6/92,6±6,3 mm Hg). The method of volumetric compression oscillometry (VCO) was used to assess a wide range of myocardial and hemodynamic parameters.Results. In AH patients, all AH phenotypes, vascular and cardiac parameters were increasing, with a simultaneous reduction in vascular wall distensibility, in parallel with the AH progression from Stage 1 to Stage 3. This indicated an increase in myocardial contractility, tone strain of arterial wall, and peripheral vascular resistance. From Stage 1 to Stage 3, the prevalence of hyper- and eukinetic cardiac hemodynamic types was decreasing, while the prevalence of mixed and hypokinetic types was increasing. The mixed hemodynamic type (a combination of hyper-, eu-, and particularly hypokinetic type characteristics) was considered as an incompletely developed disadaptive hypokinetic type.Conclusion. The VCO method is an effective, non-invasive way to simultaneously assess the status of multiple hemodynamic parameters in both healthy people and AH patients. A specific benefit of this method is the registration of lateral BP levels and identification of mixed (additional) hemodynamic type. 

scholarly journals Features of arterial hypertension in postmenopausal women with abdominal obesity: The role of inflammatory response markers, leptin, and female sex hormones in the pathogenesis of vascular wall stiffness

2019 ◽  
Vol 34 (3) ◽  
pp. 103-113 ◽  
Author(s):  
K. S. Avdeeva ◽  
T. I. Petelina ◽  
L. I. Gapon ◽  
N. A. Musikhina ◽  
E. V. Zueva
Keyword(s):  
Blood Pressure ◽  
Inflammatory Response ◽  
Arterial Hypertension ◽  
Postmenopausal Women ◽  
Sex Hormones ◽  
Abdominal Obesity ◽  
Vascular Wall ◽  
Female Sex Hormones ◽  
Wall Stiffness ◽  
Group 2

Background. Despite overall efforts, arterial hypertension remains one of the most significant medical and social problems. The risk of developing arterial hypertension is tripled in obese individuals compared with people who have normal body weight. According to clinical studies, individual biochemical markers can be predictors of initiation of remodeling processes in systems at a preclinical level. Endothelial dysfunction is the initial stage in the development of atherosclerosis. Mechanisms of the vascular inflammatory response in arterial hypertension with obesity can be considered a factor that largely determines the onset and course of the disease, a cause of its aggravation, development, and progression. Cardiovascular risk factors, genetic predisposition, deficit of sex hormones, and aging affect the endothelium function.Aim. To study specifics of hypertension in postmenopausal women with abdominal obesity and to evaluate the role of inflammatory response markers, leptin, and female sex hormones in the pathogenesis of vascular wall stiffness.Material and Methods. The study included 164 patients divided into three groups. Group 1 consisted of 42 healthy women aged 44.43 ± 14.26 years; group 2 comprised 62 hypertensive women aged 60.69 ± 7.09 years; group 3 comprised 60 hypertensive women with abdominal obesity aged 57.24 ± 7.40 years. Patients of all groups received 24-hour blood pressure monitoring, sphygmography, and assessment of sex hormones, lipids, inflammatory, and biochemical parameters in blood serum.Results. Results of analysis showed that patients of group 3 had significantly higher blood pressure compared with that in group 2. Higher pulse wave velocity was observed in women of group 2. Groups 2 and 3 had lower levels of sex hormones and significant increases in the levels of inflammatory markers compared with those in control group. Multiple multidirectional correlations between the studied parameters were revealed.Conclusions. Features of hypertension in postmenopausal women with obesity consist in a systolic-diastolic variant of hypertension, an increase in systolic blood pressure variability at night, an increase in diastolic blood pressure during the daytime, and increases in systolic and diastolic blood pressure at night. The method of logistic regression allowed to identify biochemical markers that determine the elastic properties of the vascular wall in this category of patients, namely: leptin, highsensitivity C-reactive protein, and endothelin-1. 

scholarly journals 268Regional vascular wall stiffness in apparently healthy women and their mothers with arterial hypertension

2017 ◽  
Vol 38 (suppl_1) ◽  
Author(s):  
Y. Brytkova ◽  
R. Stryuk ◽  
S. Berns ◽  
P. Krikunov ◽  
O. Tatarinova ◽  
...  
Keyword(s):  
Arterial Hypertension ◽  
Vascular Wall ◽  
Healthy Women ◽  
Wall Stiffness ◽  
Apparently Healthy

Measurement of the Propagation Velocity of Pulse Wave Generated by Ultrasound in Arteries

2005 ◽  
Author(s):  
Xiaoming Zhang ◽  
James F. Greenleaf
Keyword(s):  
Wave Velocity ◽  
Propagation Velocity ◽  
Pressure Wave ◽  
Pulse Wave ◽  
Low Frequency ◽  
Radiation Force ◽  
Frequency Wave ◽  
Reflected Waves ◽  
Wall Stiffness ◽  
Artery Stiffness

Arterial wall stiffness can be associated with various diseases. The stiffness of an artery can be assessed by measurement of the pulse wave velocity (PWV). Usually, PWV is estimated using the foot-to-foot method. However, the foot of the pressure wave is not very clear due to reflected waves. Also, the blood pressure wave generated by the heart is normally a low frequency wave, hence the time resolution is low. PWV is an average indicator of artery stiffness between two measuring locations, therefore, it is not easy to identify local stiffness. In this paper a short external pulse is generated in an artery by the radiation force of ultrasound. The propagation velocity of the pulse wave is measured along the artery. The temporal resolution of this method, which is in the range of microseconds, is much higher than the conventional pressure PWV method, and therefore allows the wave velocity to be measured accurately over a few millimeters.

Acute absolute vasodilatation is associated with a lower vascular wall stiffness in pulmonary arterial hypertension

2013 ◽  
Vol 164 (2) ◽  
pp. 227-231 ◽  
Author(s):  
Juan C. Grignola ◽  
Enric Domingo ◽  
Rio Aguilar ◽  
Manuel Vázquez ◽  
Manuel López-Messeguer ◽  
...  
Keyword(s):  
Pulmonary Arterial Hypertension ◽  
Arterial Hypertension ◽  
Vascular Wall ◽  
Wall Stiffness ◽  
Pulmonary Arterial
Sign in / Sign up

Export Citation Format

Share Document