scholarly journals Comparison of Malondialdehyde Level in the Cord Blood of Newborn Infants of vaginal and cesarean deliveries

2019 ◽  
Vol 10 (3) ◽  
pp. 2487-2494
Author(s):  
Eman Khammas ALSaadi ◽  
Batol Faisal Taher ◽  
Mohammed Abid Darweesh ◽  
Mohammed Abul Al-Monther
Keyword(s):  
Oxidative Stress ◽  
Cesarean Section ◽  
Cord Blood ◽  
Vaginal Delivery ◽  
Oxidative Stress Marker ◽  
Elective Cesarean Section ◽  
Stress Injury ◽  
Vaginal Deliveries ◽  
Two Samples ◽  
Elective Cesarean

The oxidative stress injury that has been linked to poor perinatal outcome and birth asphyxia may be found even with normal pregnancy, and it is severity in a newborn may be related to modes of delivery for which our study aimed to identify. Furthermore, this study was aimed to study the effect of both related- maternal, and related neonatal characteristics on baby’s oxidative stress marker level (Malondialdehyde). Fifty newborn children were selected in both labor ward and operating theatre of Al-Sadder Teaching Hospital, Misan, Iraq. They were divided into two groups. The first group comprised 28 newborns, who were born by a vaginal delivery; the second group consisted of 22 newborns who delivered by elective cesarean section. The laboratory measurement of levels of an important antioxidant factor [malondialdehyde (MDA)] in baby’s cord blood has been extracted and used as an indicator of stress. We compared the two samples of different malondialdehyde levels in relation to variables as the delivery type, some maternal, fetal and neonatal characteristics. The results of this study revealed that MDA level was higher among neonates delivered through Elective Cesareans Section than those delivered through Vaginal Delivery with significant statistical value (p>0.0001). The previous delivery mood has a statistically significant value of (p>0.02) among mothers who had no previous deliveries.  While there were no significant statistical values regarding maternal characteristics as (ages, parity, residency, antenatal care, history of previous abortion, and body mass index) as well as fetal and neonatal characteristics as (sex, birth weight, fetal presentation, and Apgar score) and high MDA level. The current study was concluded that babies delivered by Elective Cesarean Section had been exposed to more oxidative stress compared to the normal Vaginal Deliveries especially for the Primigravidas.

scholarly journals Anandamide Exerts a Differential Effect on Human Placenta Before and After the Onset of Labor

2021 ◽  
Vol 12 ◽  
Author(s):  
Paula Accialini ◽  
Cyntia Abán ◽  
Tomás Etcheverry ◽  
Mercedes Negri Malbrán ◽  
Gustavo Leguizamón ◽  
...  
Keyword(s):  
Cesarean Section ◽  
Vaginal Delivery ◽  
Endocannabinoid System ◽  
Cesarean Sections ◽  
Vaginal Deliveries ◽  
Before And After ◽  
Elective Cesarean ◽  
Main Components ◽  
Relevant Finding

The onset of labor involves the action of multiple factors and recent reports have postulated the endocannabinoid system as a new regulator of this process. Our objective was to study the role of anandamide, one of the main endocannabinoids, on the regulation of placental molecules that contribute to the onset of labor at term. Placental samples were obtained from patients with laboring vaginal deliveries and from non-laboring elective cesarean sections. Vaginal delivery placentas produced higher prostaglandins levels than cesarean section samples. Besides, no differences were observed in NOS basal activity between groups. Incubation of vaginal delivery placentas with anandamide increased prostaglandins concentration and decreased NOS activity. Antagonism of type-1cannabinoid receptor (CB1) did not alter the effect observed on NOS activity. Conversely, incubation of cesarean section placentas with anandamide reduced prostaglandins levels and enhanced NOS activity, the latter involving the participation of CB1. Furthermore, we observed a differential expression of the main components of the endocannabinoid system between placental samples, being the change in CB1 localization the most relevant finding. Our results suggest that anandamide acts as a modulator of the signals that regulate labor, exerting differential actions depending on CB1 localization in laboring or non-laboring term placentas.

Effects of sevoflurane and desflurane on oxidative stress during general anesthesia for elective cesarean section

2013 ◽  
Vol 125 (15-16) ◽  
pp. 467-473 ◽  
Author(s):  
Saban Yalcin ◽  
Harun Aydoğan ◽  
Hasan Husnu Yuce ◽  
Ahmet Kucuk ◽  
Mahmut Alp Karahan ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Cesarean Section ◽  
General Anesthesia ◽  
Elective Cesarean Section ◽  
Elective Cesarean

Comparison of Melatonin Levels in the Colostrum between Vaginal Delivery and Cesarean Delivery

2017 ◽  
Vol 35 (05) ◽  
pp. 481-485 ◽  
Author(s):  
Ziya Kalem ◽  
Tuncay Yuce ◽  
Batuhan Bakırarar ◽  
Feride Söylemez ◽  
Müberra Namlı Kalem
Keyword(s):  
Cesarean Section ◽  
Cesarean Delivery ◽  
Vaginal Delivery ◽  
Mode Of Delivery ◽  
Elective Cesarean Section ◽  
Enzyme Linked Immunosorbent Assay ◽  
Cross Sectional ◽  
Emergency Cesarean ◽  
Study Results ◽  
Elective Cesarean

Objective This study aims to compare melatonin levels in colostrum between vaginal and cesarean delivery. Study Design This cross-sectional study was conducted with 139 mothers who gave live births between February 2016 and December 2016. The mothers were divided into three groups according to the mode of delivery: 60 mothers (43.2%) in the vaginal delivery group, 47 mothers (33.8%) in the elective cesarean delivery, and 32 mothers (23.0%) in the emergency cesarean delivery group. Colostrum of the mothers was taken between 01:00 and 03:00 a.m. within 48 to 72 hours following the delivery, and the melatonin levels were measured using the enzyme-linked immunosorbent assay (ELISA) and compared between the groups. Results The melatonin levels in the colostrum were the highest in the vaginal delivery group, lower in the elective cesarean section group, and the lowest in the emergency cesarean group (265.7 ± 74.3, 204.9 ± 55.6, and 167.1 ± 48.1, respectively; p < 0.001). The melatonin levels in the colostrum did not differ according to the demographic characteristics of the mothers, gestational age, birth weight, newborn sex, the Appearance, Pulse, Grimace, Activity, and Respiration (APGAR) scores, and for the requirement for neonatal intensive care. Conclusion Our study results showed that melatonin levels in the colostrum of the mothers who delivered vaginally were higher than those who delivered by cesarean section. Considering the known benefits of melatonin for the newborns, we believe that vaginal delivery poses an advantage.

scholarly journals Factors Associated with the Type of Cesarean Section and the Risk of Postoperative Complications in Greek Women

2020 ◽  
Author(s):  
Evangelia Antoniou ◽  
Eirini Orovou ◽  
Maria Iliadou ◽  
Angeliki Sarella ◽  
Ermioni Palaska ◽  
...  
Keyword(s):  
Postoperative Complications ◽  
Cesarean Section ◽  
Stress Disorders ◽  
Delivery Rate ◽  
Elective Cesarean Section ◽  
Emergency Cesarean Section ◽  
Cesarean Deliveries ◽  
Emergency Cesarean ◽  
Vaginal Deliveries ◽  
Elective Cesarean

Abstract Background Cesarean Section was historically performed to save the lives of mothers and infants. Ηowever, in the past decades, a significant increase in Cesarean Section rates have been observed in Greece and worldwide. The purpose of this research was to investigate the contributing factors to the increase in the Cesarean Section rate (emergency and elective) and postoperative complications.Methods A total of births in 6 months (August 2019- February 2020) at the University Hospital of Larisa in Greece was collected. The performed analysis included the available socio-demographic and medical information in the medical records and a socio-demographic and medical questionnaire for women with cesarean deliveries. We also analyzed the importance of the variables in cesarean deliveries compared to vaginal deliveries and postoperative complications.Results Out of the total number of the included 633 births, the vaginal delivery rate was 42% (n = 268), and the cesarean delivery rate was 58% (n = 365); Elective Cesarean Section was performed in 36% (n = 230) of the Cesarean Section cases and Emergency Cesarean Section in 22% (n = 135). Women with a previous Cesarean Section and women with in vitro fertilization showed higher percentages for Elective Cesarean Section (46%) compared to women who underwent an Emergency Cesarean Section for the same reasons (42.2%). Besides, a higher percentage of Emergency Cesarean Sections was observed in women living in urban centers (OR = 4.044, p = 0.002) and those diagnosed with stress disorders (OR = 7.048, p = 0.004). Furthermore, Cesarean Section complications were more common among women having undergone Emergency Cesarean Section (OR = 10.357, p < 0.001).Conclusion The overall high rates of Cesarean Section in Greece demonstrate the lack of national strategies and prevention mechanisms from iatrogenic interventions and lack of promoting good midwifery practices. More specifically, a decrease in iatrogenic factors leading to the primary Cesarean Section will decrease Cesarean Section rates in Greece.

scholarly journals Perbandingan Nilai Apgar antara Persalinan Normal dengan Seksio Sesarea Elektif

2016 ◽  
Vol 5 (1) ◽  
Author(s):  
Neila Azka ◽  
Syahredi Syahredi ◽  
Eva Chundrayetti
Keyword(s):  
Cesarean Section ◽  
Vaginal Delivery ◽  
Apgar Score ◽  
Cross Sectional Study ◽  
Elective Cesarean Section ◽  
Normal Vaginal Delivery ◽  
Sectional Study ◽  
Cross Sectional ◽  
Elective Cesarean ◽  
Minute Apgar Score

AbstrakPada masa sekarang ini telah terjadi perubahan tren dalam persalinan, yaitu berupa peningkatan angka seksio sesarea. Peningkatan ini dipengaruhi berbagai faktor seperti: adanya kekhawatiran akan terjadinya cedera janin, peningkatan permintaan ibu untuk melakukan persalinan seksio sesarea, serta faktor sosioekonomi. Beberapa penelitian justru menunjukkan seksio sesarea dapat menimbulkan morbiditas pada bayi. Tujuan penelitian ini adalah membandingkan kondisi bayi antara persalinan normal dan seksio sesarea elektif dilihat dari nilai Apgar Penelitian dilaksanakan dari Mei 2014 sampai Januari 2014 di bagian rekam medis RSUP Dr. M. Djamil Padang.. Jenis penelitian yang digunakan adalah analitik dengan desain cross-sectional study. Sampel dalam penelitian ini terdiri dari 179  pasien dengan persalinan normal dan 56 pasien dengan seksio sesarea. Hasil penelitian menunjukkan bahwa pada menit pertama nilai Apgar 4-6 adalah 3,4% pada persalinan normal. Nilai Apgar 7-10 sebanyak 96,6% pada persalinan normal dan 100% pada seksio sesarea pada menit pertama. Pada menit kelima, nilai Apgar 4-6 adalah 1,1% pada persalinan normal, sedangkan nilai Apgar 7-10 sebanyak 98,9% pada persalinan normal dan 100% pada seksio sesarea pada menit kelima. Setelah dilakukan analisis dengan mann-whitney test didapatkan bahwa tidak terdapat perbedaan nilai Apgar pada menit-1 (p=0,777) dan menit-5 (p=0,887) antara persalinan normal dengan seksio sesarea.Kata kunci: persalinan normal, seksio sesarea elektif, nilai Apgar AbstractIn recent years, cesarean section have increased. Several factor are contributing, such as fears of injury to the fetus, increased women's request to do a cesarean section deliveries and socioeconomic factors. Some studies have also shown that cesarean section can lead to morbidity in infants. The objective of this study was to compare between Apgar scores of infant born by elective cesarean section and normal vaginal deliveries. The research was done from May 2013 to January 2014 at the medical records department of general hospital center Dr. M. Djamil Padang. This was an analytic study with cross-sectional study design. This study used 179 samples with normal vaginal delivery and 56 samples with cesarean section. The result showed that 1st minute Apgar score of 4-6 in normal vaginal delivery was 3.4%, and Apgar score 7-10 was 96.6% in normal vaginal delivery while in cesarean section was 100%. The 5th minute Apgar score of  4-6 in normal vaginal delivery was 1.1%, and Apgar score 7-10 was 98.9% in normal vaginal delivery while in cesarean section was 100%. After being analyzed using Mann-Whitney test, the study showed that there was no significant different in Apgar score of neonates born through normal vaginal delivery and neonates born trough cesarean section at first minute (p=0.777) and fifth minute (p=0.887).Keywords: normal vaginal delivery, elective cesarean section, Apgar score

Oxygen saturation trends in normal healthy term newborns: normal vaginal delivery vs. elective cesarean section

2018 ◽  
Vol 46 (2) ◽  
pp. 191-195 ◽  
Author(s):  
Rashi Bhargava ◽  
Madhu Mathur ◽  
Jyoti Patodia
Keyword(s):  
Birth Weight ◽  
Cesarean Section ◽  
Oxygen Saturation ◽  
Vaginal Delivery ◽  
Neonatal Resuscitation ◽  
Elective Cesarean Section ◽  
Normal Vaginal Delivery ◽  
Elective Cesarean ◽  
Term Newborns ◽  
The Mean

AbstractObjectives:To study the normal oxygen saturation trends and fetomaternal correlates in healthy term newborns within 30 min of life born by normal vaginal delivery (NVD) and elective cesarean section (CS).Materials and methods::A cross-sectional study was conducted on 200 healthy term newborns born by NVD and elective CS at a tertiary care centre. Routine care as per the Neonatal Resuscitation Program (NRP) 2015 (Wyckoff MH, Aziz K, Escobedo MB, Kapadia VS, Kattwinkel J, Perlman JM, et al. Part 13: neonatal resuscitation: 2015 American Heart Association guidelines update for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation. 2015;132:S543–60) protocol was given and pre-ductal arterial oxygen saturation was assessed by pulse oximetry at different intervals after birth.Results:The mean peripheral oxygen saturation (SpO2) was 85.4%, 90.8%, 94.1%, 95.7%, 96.7% and 97.4% at 5, 10, 15, 20, 25 and 30 min, respectively, after birth. Higher mean SpO2was observed in NVD compared to elective CS (P<0.005). The mean time for SpO2to reach >90% was 9.13 min in NVD and 12.31 min in elective CS (P<0.001). Maternal hemoglobin (Hb) (r=−0.15; P<0.01), birth weight (r=−0.125; P<0.05) and Apgar at 10 min (r=0.33; P<0.001) were significantly correlated with SpO2of newborns at 10 min of life.Conclusion:Our study defines normal SpO2levels in healthy term newborns in the first 30 min of life born by NVD and elective CS. Babies born by NVD had significantly higher SpO2levels and attained SpO2>90% faster than those born by elective CS. Maternal Hb, birth weight and Apgar at 10 min were significant factors affecting SpO2levels of newborns at 10 min of life.

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