Comparison of effect of anticholinergic premedication on intubation condition and time on induction with low dose rocuronium in children undergoing short surgical procedures

2020 ◽  
Vol 17 (3) ◽  
pp. 118-121
Author(s):  
Akanksha Aggarwal ◽  
2012 ◽  
Vol 27 (1) ◽  
pp. 7-11 ◽  
Author(s):  
Ji Young Kim ◽  
Jong Seok Lee ◽  
Hee Yeon Park ◽  
Yong Beom Kim ◽  
Youngjun Kwon ◽  
...  

2012 ◽  
Vol 7 (4) ◽  
pp. 53-57
Author(s):  
RK Yadav ◽  
PC Majhi ◽  
BB Pradhan

As use of suxamethonium is associated with a large number of undesirable and serious side effects, including cardiac arrhythmias and malignant hyperthermia. These undesirable effects have prompted anesthesiologists to restrict use of suxamethonium. The low dose of the drug is expected to have lower side effects without compromising its neuromuscular blocking properties as the dose dependent side effects have been known for long, so the present study carried out to compare the efficacy of high dose (1.5mg/Kg) of suxamethonium to that of low dose (0.5mg/Kg) assessed by intubation condition with neuromuscular blockade. We prospectively randomized and compared the intubating conditions with neuromuscular monitoring in 100 patients undergoing elective abdominal, gynaecological and limb surgery in CMS-TH and found duration of apnoea and time taken for recovery of twitch height was significantly shorter. Without compromising the quality of neuromuscular blockade. Suxamethonium or Succinylcholine can be used in lower doses (0.5 mg/kg) in elective cases without airway compromise to achieve intubation. Journal of College of Medical Sciences-Nepal,2011,Vol-7,No-4, 53-57 DOI: http://dx.doi.org/10.3126/jcmsn.v7i4.6812 


2000 ◽  
Vol 131 (3) ◽  
pp. 331-335 ◽  
Author(s):  
LEON ARDEKIAN ◽  
RONEN GASPAR ◽  
MICHA PELED ◽  
BENJAMIN BRENER ◽  
DOV LAUFER

Author(s):  
T. M. Seed ◽  
M. H. Sanderson ◽  
D. L. Gutzeit ◽  
T. E. Fritz ◽  
D. V. Tolle ◽  
...  

The developing mammalian fetus is thought to be highly sensitive to ionizing radiation. However, dose, dose-rate relationships are not well established, especially the long term effects of protracted, low-dose exposure. A previous report (1) has indicated that bred beagle bitches exposed to daily doses of 5 to 35 R 60Co gamma rays throughout gestation can produce viable, seemingly normal offspring. Puppies irradiated in utero are distinguishable from controls only by their smaller size, dental abnormalities, and, in adulthood, by their inability to bear young.We report here our preliminary microscopic evaluation of ovarian pathology in young pups continuously irradiated throughout gestation at daily (22 h/day) dose rates of either 0.4, 1.0, 2.5, or 5.0 R/day of gamma rays from an attenuated 60Co source. Pups from non-irradiated bitches served as controls. Experimental animals were evaluated clinically and hematologically (control + 5.0 R/day pups) at regular intervals.


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