scholarly journals Influence of ICG-technology on the results of surgical treatment of early forms of breast cancer

2021 ◽  
Vol 26 (2) ◽  
pp. 67-72
Author(s):  
J. Masia ◽  
O.Y. Savenkov
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Surgical Treatment ◽  
Sentinel Lymph Node ◽  
Intraoperative Imaging ◽  
Surgical Techniques ◽  
Main Group ◽  
Control Group ◽  
Subcutaneous Mastectomy ◽  
Tumor Spread

Breast cancer (BC) is one of the most common causes of death in women up to 50 years old. For today the choice of an adequate methods of surgical intervention and the need for an adequate surgical adjuvant therapy, quality of life of patients after surgeryis are important. The aim of our study was to select the volume of surgery for breast cancer using the technique of intraoperative identification of the sentinel lymph node (intraoperative ICG technology) and to evaluate the results of its urgent histological examination. It was shown that the most common method of surgery in patients who underwent intraoperative ICG technology was quadrantectomy, which was performed in 27 cases (54%), rarely subcutaneous mastectomy was performed (30%) and radical mastectomy (by Madden) – 16%. In the control group, priority was given to radical removal of the breast (63.2% of cases); partial resection (by U. Veronesi) was performed in 33.3% of patients, and subcutaneous mastectomy – in 3.5%. Pathomorphological examination of the sentinel lymph node during its intraoperative imaging using ICG-technology established metastatic lesion in 10 of 50 cases (20%) in the main group. The obtained results of the assessment of the regional lymph dissection size in the main group indicate its adequate nature to ensure the radicality of surgical treatment. In our opinion, this is one of the important preliminary conclusions of this study, because to assess the clinical significance of signal lymph node (SLN) analysis as a marker of regional tumor spread, firstly it is necessary to be sured that existing surgical techniques provide radical tumor removal.

scholarly journals Minimum Invasive Stabilizing and Decompressive-Stabilizing Methods of Surgical Treatment for Degenerative-Dystrophic Lesions of Spine

2011 ◽  
Vol 18 (4) ◽  
pp. 3-10
Author(s):  
A V Krut'ko ◽  
Shamil' Al'firovich Akhmet'yanov ◽  
D M Kozlov ◽  
A V Peleganchuk ◽  
A V Bulatov ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Lumbar Spine ◽  
Surgical Techniques ◽  
Pain Syndrome ◽  
Early Postoperative Period ◽  
Main Group ◽  
Control Group ◽  
Surgical Interventions ◽  
Comparative Group ◽  
Operative Wound

Results of randomized prospective study with participation of 94 patients aged from 20 to 70 years with monosegmental lumbar spine lesions are presented. Minimum invasive surgical interventions were performed in 55 patients from the main group. Control group consisted of 39 patients in whom decompressive-stabilizing operations via conventional posteromedian approach with skeletization of posterior segments of vertebral column were performed. Average size of operative wound in open interventions more than 10 times exceeded that size in minimum invasive interventions and made up 484 ± 56 and 36 ± 12 sq.cm, respectively. Mean blood loss was 326.6 ± 278.0 ml in the main group and 855.1 ± 512.0 ml in the comparative one. In the main group no one patient required substitution hemotransfusion, while in 13 patients from the comparative group donor erythrocytic mass and/or fresh-frozen plasma were used to eliminate the deficit of blood components. Intensity of pain syndrome in the zone of surgical intervention by visual analog scale in the main group was lower than in comparative group. In the main and comparative groups the duration of hospitalization made up 6.1 ± 2.7 and 9.7 ± 3.7 bed days, respectively. In no one patient from the main group complications in the zone of operative wound were noted. Three patients from the comparative group required secondary debridement and in 1 patient early deep operative wound suppuration was observed. Application of low invasive surgical techniques for the treatment of patients with degenerative lumbar spine lesions enabled to perform radical surgical treatment with minimal iatrogenic injury. The method possessed indubitable advantages over the conventional open operations especially intraoperatively and in early postoperative period.

scholarly journals Defining the Optimal Surgeon Experience for Breast Cancer Sentinel Lymph Node Biopsy: A Model for Implementation of New Surgical Techniques

2001 ◽  
Vol 234 (3) ◽  
pp. 292-300 ◽  
Author(s):  
Kelly M. McMasters ◽  
Sandra L. Wong ◽  
Celia Chao ◽  
Claudine Woo ◽  
Todd M. Tuttle ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
Surgical Techniques ◽  
Lymph Node Biopsy ◽  
Node Biopsy ◽  
Surgeon Experience

scholarly journals Effectiveness of Physiotherapy Intervention on the Quality of Life of Women with Breast Cancer who Underwent Sentinel Lymph Node Biopsy.

2017 ◽  
Vol 2 (4) ◽  
Author(s):  
Nuno Miguel Duarte ◽  
Pedro Aguiar ◽  
Paula Lobato Faria ◽  
Mario Bernardo
Keyword(s):  
Breast Cancer ◽  
Quality Of Life ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Lower Risk ◽  
Lymph Node Biopsy ◽  
Control Group ◽  
Node Biopsy ◽  
Experimental Group

Purpose: To evaluate if physiotherapy can contribute to the quality of service provided to Women with Breast Cancer who underwent sentinel lymph node biopsy (SLNB).Methods: This Quasi-experimental study addressed a sample of 172 women with breast cancer who underwent surgery with SLNB, 90 were included in the control group and 82 in the experimental group. We used the EORTC C30 and BR23 questionnaires to collect data about the quality of life (QoL) in the course of the first 9 months after surgery. The experimental group was submitted to specific physiotherapy techniques while the control group was the target of assessments only. Poisson regression was used to perform the calculation of the Relative Benefit (aRB) and Relative Risk (aRR) adjusted for several confounding factors at the baseline of the study.Results: In the third month after surgery the experimental group showed a higher proportion of patients with substantial clinical improvement in the Global Health Status (GHS) (aRB=2.230; p=0.014) and a lower risk of degradation of the GHS (aRR=0.384; p=0.011), Physical Function (PF) (aRR=0.484; p=0.035), and Arm Symptoms (BRAS) (aRR=0.159; p=0.007), when compared to the control group. Between the 1st and 6th month after surgery, physiotherapy seems to act as a protective factor on the degradation of GHS and PF. Between the 1st and 9th month after surgery the experimental group showed a higher proportion of patients with notable clinical improvement in the GHS (aRB=1.905; p=0.038) and in the BRAS (aRB=1.761; p=0.029) and a lower risk of degradation of the GHS (aRR=0.287; p=0.010) and BRAS (aRR=0.265; p=0.0421) scales.Conclusions: In the course of the acute survival phase, physiotherapy can help to improve the QoL of women with breast cancer who underwent surgeries with SLNB, giving a positive contribution to the quality of service provided to this group of patients.

scholarly journals A Review and Current Update on Sentinel Lymph Node Biopsy of Breast Cancer

2020 ◽  
Vol 8 (F) ◽  
pp. 78-83
Author(s):  
Stacia Novia Marta ◽  
Nyoman Dwi Aussi Hary Mastika ◽  
Hendry Irawan
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Surgical Treatment ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
Neoadjuvant Chemotherapy ◽  
Lymphatic Mapping ◽  
Early Cancer ◽  
Lymph Node Biopsy ◽  
Node Biopsy

Sentinel lymph node biopsy (SLNB) has become the standard staging technique in the surgical treatment of breast cancer, replacing the older method of dissecting lymph nodes of the axilla. Several advantages like lowering of the morbidities that accompany the technique and being less invasive have given rise to a promising effect on life aspects of patients suffering from this morbidity. The procedure has evolved over the last few decades, but further studies are still needed to make improvements. Several aspects of the evolution of SLNB, such as the incorporation of the management in early cancer, the technique of lymphatic mapping, the accuracy of the technique, and its utility and evaluation in clinical response after neoadjuvant chemotherapy are discussed in this review.  

Routine use of sentinel lymph node surgery in patients undergoing prophylactic mastectomy: A decision analysis model

2006 ◽  
Vol 24 (18_suppl) ◽  
pp. 607-607
Author(s):  
J. C. Boughey ◽  
J. N. Cormier ◽  
Y. Xing ◽  
F. Meric-Bernstam ◽  
M. I. Ross ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Surgical Treatment ◽  
Sentinel Lymph Node ◽  
Decision Analysis ◽  
Prophylactic Mastectomy ◽  
Invasive Cancer ◽  
Decision Analysis Model ◽  
Analysis Model ◽  
Node Negative

607 Background: Patients with invasive carcinoma identified following prophylactic mastectomy (PM) require axillary lymph node dissection (ALND) for nodal staging as standard surgical treatment. Since most patients will be node negative, sentinel lymph node (SLN) surgery has been advocated to avoid the sequelae of unnecessary axillary surgery. However, since SLN surgery is not without complications and the incidence of invasive cancer in PM is extremely low, we sought to compare surgical strategies using a decision analysis model in order to define the true risks and benefits of routine SLN surgery versus standard surgical treatment (ALND). Methods: Model estimates were derived by systematic review of the literature. The outcomes examined were: (1) the number of SLN procedures that would need to be performed to avoid one ALND in a pathologically node negative patient; and (2) the probability of long-term axillary complications with each strategy. Occult breast cancer was defined as invasive cancer in the PM specimen and/or SLN metastases. Results: The following weighted averages were used to inform the model: i) incidence of invasive cancer in PM of 1%, ii) incidence of nodal disease of 25% in the presence of invasive breast cancer and 1% in the absence of invasive cancer in the breast, and iii) incidence of complications after ALND of 30% and after SLN surgery of 6%. Routine use of SLN surgery doubled the sensitivity for detection of carcinoma compared to ALND. However, 133 SLN procedures were required to avoid one ALND in a node negative PM patient. Additionally, the probability of complications per breast cancer detected was 10-fold greater with the SLN strategy. When the risk of breast cancer was projected at 10%, 13 SLN procedures were required to avoid one negative ALND and the complication rate per cancer detected was 2-fold greater in the SLN arm. Conclusions: The benefit of adding SLN surgery in patients undergoing PM depends on the probability of detecting invasive cancer. Routine SLN surgery in PM is not warranted given the large number of procedures required to benefit one patient and the complications associated with performing SLN surgery in all patients. However, the SLN strategy may be appropriate for subgroups of patients at higher risk of occult carcinoma. No significant financial relationships to disclose.

Sentinel lymph node biopsy as the new standard of care in the surgical treatment for breast cancer

2006 ◽  
Vol 6 (10) ◽  
pp. 1503-1515 ◽  
Author(s):  
Alberta Ferrari ◽  
Francesca Rovera ◽  
Paolo Dionigi ◽  
Giorgio Limonta ◽  
Marina Marelli ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lymph Node ◽  
Surgical Treatment ◽  
Sentinel Lymph Node ◽  
Sentinel Lymph Node Biopsy ◽  
Standard Of Care ◽  
Lymph Node Biopsy ◽  
Node Biopsy
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