scholarly journals From closed to open. Democratising medical devices using additive manufacture and open source development and distribution systems.

2021 ◽  
Author(s):  
Callum Allen
Keyword(s):  
3D Printing ◽  
Data Collection ◽  
Open Source ◽  
Blue Light ◽  
Medical Devices ◽  
Distribution Systems ◽  
Printing Technology ◽  
3D Printing Technology ◽  
Research Through Design ◽  
Open Source Development

<p><b>Pupils can provide important neurological information that can aid in the diagnosis of a range of conditions, including aneurysms, impending strokes and tumors in the lung (Gale, et al). In a research context, there is increasing interest in studying the intrinsically photosensitive Retinal Ganglion cells (ipRGC), which respond to intense blue light thanks to a photo pigment called melanopsin. Studying these cells could lead to a better understanding of sleep disorders and a range of optic nerve diseases. Although commercially available pupil testing devices do exist, all cost upwards of $10,000, and suffer from either poor portability or limitations in the tests they can perform. Specifically, the ipRGC require a specific intensity of blue light to be activated and measured, which most devices cannot produce. </b></p><p>In recent years, the open source movement has enabled users from around the world to freely collaborate on the development and distribution of their own products. At first, only software could be produced using this approach, however the continued improvement of 3D printing technology has enabled the same model to be applied to physical products as well. From a medical perspective, this is particularly exciting. </p><p>The aim of this research was to produce an inexpensive, open source pupilometer that runs on widely available components, can be distributed online and manufactured using 3D printing technology. In doing so, this thesis asks the question; How can an open source development and distribution model be used in conjunction with online 3D printing services and widely available parts and components to produce an inexpensive and open source pupilometer? </p><p>To answer this, a range of practice based methodologies, including research for design and research through design were used to explore this new potential. The resulting design proposal demonstrates how online file sharing platforms, in conjunction with distributed 3D printing services and online supply chains can be combined to develop new medical devices. The ability to collect pupil data using an open source pupilometer may lead to expanded data collection and diagnostic capabilities from doctors in a number of clinical settings, while a cloud based data collection system taking the form of a smartphone app will create a large biometric database and cooperative online research community. </p>

scholarly journals From closed to open. Democratising medical devices using additive manufacture and open source development and distribution systems.

2021 ◽  
Author(s):  
Callum Allen
Keyword(s):  
3D Printing ◽  
Data Collection ◽  
Open Source ◽  
Blue Light ◽  
Medical Devices ◽  
Distribution Systems ◽  
Printing Technology ◽  
3D Printing Technology ◽  
Research Through Design ◽  
Open Source Development

<p><b>Pupils can provide important neurological information that can aid in the diagnosis of a range of conditions, including aneurysms, impending strokes and tumors in the lung (Gale, et al). In a research context, there is increasing interest in studying the intrinsically photosensitive Retinal Ganglion cells (ipRGC), which respond to intense blue light thanks to a photo pigment called melanopsin. Studying these cells could lead to a better understanding of sleep disorders and a range of optic nerve diseases. Although commercially available pupil testing devices do exist, all cost upwards of $10,000, and suffer from either poor portability or limitations in the tests they can perform. Specifically, the ipRGC require a specific intensity of blue light to be activated and measured, which most devices cannot produce. </b></p><p>In recent years, the open source movement has enabled users from around the world to freely collaborate on the development and distribution of their own products. At first, only software could be produced using this approach, however the continued improvement of 3D printing technology has enabled the same model to be applied to physical products as well. From a medical perspective, this is particularly exciting. </p><p>The aim of this research was to produce an inexpensive, open source pupilometer that runs on widely available components, can be distributed online and manufactured using 3D printing technology. In doing so, this thesis asks the question; How can an open source development and distribution model be used in conjunction with online 3D printing services and widely available parts and components to produce an inexpensive and open source pupilometer? </p><p>To answer this, a range of practice based methodologies, including research for design and research through design were used to explore this new potential. The resulting design proposal demonstrates how online file sharing platforms, in conjunction with distributed 3D printing services and online supply chains can be combined to develop new medical devices. The ability to collect pupil data using an open source pupilometer may lead to expanded data collection and diagnostic capabilities from doctors in a number of clinical settings, while a cloud based data collection system taking the form of a smartphone app will create a large biometric database and cooperative online research community. </p>

scholarly journals From closed to open. Democratising medical devices using additive manufacture and open source development and distribution systems.

2021 ◽  
Author(s):  
Callum Allen
Keyword(s):  
3D Printing ◽  
Data Collection ◽  
Open Source ◽  
Blue Light ◽  
Medical Devices ◽  
Distribution Systems ◽  
Printing Technology ◽  
3D Printing Technology ◽  
Research Through Design ◽  
Open Source Development

<p><b>Pupils can provide important neurological information that can aid in the diagnosis of a range of conditions, including aneurysms, impending strokes and tumors in the lung (Gale, et al). In a research context, there is increasing interest in studying the intrinsically photosensitive Retinal Ganglion cells (ipRGC), which respond to intense blue light thanks to a photo pigment called melanopsin. Studying these cells could lead to a better understanding of sleep disorders and a range of optic nerve diseases. Although commercially available pupil testing devices do exist, all cost upwards of $10,000, and suffer from either poor portability or limitations in the tests they can perform. Specifically, the ipRGC require a specific intensity of blue light to be activated and measured, which most devices cannot produce. </b></p><p>In recent years, the open source movement has enabled users from around the world to freely collaborate on the development and distribution of their own products. At first, only software could be produced using this approach, however the continued improvement of 3D printing technology has enabled the same model to be applied to physical products as well. From a medical perspective, this is particularly exciting. </p><p>The aim of this research was to produce an inexpensive, open source pupilometer that runs on widely available components, can be distributed online and manufactured using 3D printing technology. In doing so, this thesis asks the question; How can an open source development and distribution model be used in conjunction with online 3D printing services and widely available parts and components to produce an inexpensive and open source pupilometer? </p><p>To answer this, a range of practice based methodologies, including research for design and research through design were used to explore this new potential. The resulting design proposal demonstrates how online file sharing platforms, in conjunction with distributed 3D printing services and online supply chains can be combined to develop new medical devices. The ability to collect pupil data using an open source pupilometer may lead to expanded data collection and diagnostic capabilities from doctors in a number of clinical settings, while a cloud based data collection system taking the form of a smartphone app will create a large biometric database and cooperative online research community. </p>

scholarly journals Coumarins as Powerful Photosensitizers for the Cationic Polymerization of Epoxy-Silicones under Near-UV and Visible Light and Applications for 3D Printing Technology

Molecules ◽  
2020 ◽  
Vol 25 (9) ◽  
pp. 2063 ◽  
Author(s):  
Mira Abdallah ◽  
Akram Hijazi ◽  
Frédéric Dumur ◽  
Jacques Lalevée
Keyword(s):  
3D Printing ◽  
Visible Light ◽  
Blue Light ◽  
Laser Diode ◽  
Cationic Polymerization ◽  
High Performance ◽  
Printing Technology ◽  
3D Printing Technology ◽  
Visible Irradiation

In this study, eight coumarins (coumarins 1–8) are proposed as near-UV and blue light sensitive photoinitiators/photosensitizers for the cationic polymerization (CP) of epoxysilicones when combined with 4-isopropyl-4’-methyldiphenyliodonium tetrakis(pentafluorophenyl)borate (IOD). Among these coumarins, four of them (coumarins 1, 2, 6 and 8) have never been reported in the literature, i.e., these structures have been specifically designed to act as photoinitiators for silicones upon near UV and visible irradiation. Good final reactive epoxy function conversions (FCs) and also high rates of polymerization (Rp) were achieved in the presence of the newly proposed coumarin-based systems. The polymers generated from the photopolymerization of epoxysilicones can be considered as attractive candidates for several applications such as: elastomers, coatings, adhesives, and so on. The goal of this study focuses also on the comparison of the new proposed coumarins with well-established photosensitizers i.e., 1-chloro-4-propoxythioxanthone (CPTX), 9,10-dibutoxyanthracene (DBA) or some commercial coumarins (Com. Coum). As example of their high performance, the new proposed coumarins were also used for laser write experiments upon irradiation with a laser diode at 405 nm in order to develop new cationic 3D printing systems.

scholarly journals Recent Trends, Opportunities and Challenges in 3D Printing Technology for Personalize Medicine

2020 ◽  
Vol 10 (4) ◽  
pp. 242-252
Author(s):  
Shrikrishna T. Mule ◽  
O.G. Bhusnure ◽  
S.S. Waghmare ◽  
Mamta R. Mali
Keyword(s):  
Pharmaceutical Industry ◽  
3D Printing ◽  
Medical Devices ◽  
Drug Product ◽  
Production Method ◽  
Current Status ◽  
Printing Technology ◽  
3D Printing Technology ◽  
Drug Products ◽  
Personalize Medicine

The scrutiny of medical devices industry as well as pharmaceutical industry for its application in health care industry on different platform is captured the 3D printing technique.  3D printing technology withstand for a very long duration only because of the approval of medical devices, 3D printed tablets and also with the advent of USFDA guideline on technical consideration. This technology is specific to devices utilizing preservative manufacturing. Many thoughts are triggered by 3D printing this technology and for successful delivery of intended product which is necessarily take into a consideration. In this review paper expectation limitations of some regulatory companies, Advantages, disadvantages, what type problems are arises while establishing this setups for drug product production, method, application, and manufacturing risk are represented. It also gives information about the current status of 3D printing technology in research and development of drug products.  For the fabrication of novel solid dosage form a number of 3D printing technology have been developed. This review is mainly focused on describing different technology used for the application of 3D printing in pharmaceutical industry.  Keywords: - 3D printing technology, recent trend, Opportunities, personalize medicine, challenges, future.

scholarly journals A Portable 3D-Printed Platform for Point-of-Care Diagnosis of Clostridium Difficile Infection and Malaria

2019 ◽  
Author(s):  
Soichiro Tsuda ◽  
Lewis A. Fraser ◽  
Salah Sharabi ◽  
Mohammed Hezwani ◽  
Andrew Kinghorn ◽  
...  
Keyword(s):  
Clostridium Difficile ◽  
3D Printing ◽  
Open Source ◽  
Clostridium Difficile Infection ◽  
Point Of Care ◽  
Low Cost ◽  
Clinical Applications ◽  
Printing Technology ◽  
3D Printing Technology ◽  
3D Printed

Here, we integrate 3D-printing technology with low-cost open source electronics to develop a portable diagnostic platform suitable for a wide variety of diagnostic and sensing assays. We demonstrate two different clinical applications in the diagnosis of <i>Clostridium difficile</i> infection and malaria.

scholarly journals Powder-Based 3D Printing for the Fabrication of Device with Micro and Mesoscale Features

Micromachines ◽  
2020 ◽  
Vol 11 (7) ◽  
pp. 658 ◽  
Author(s):  
Seow Yong Chin ◽  
Vishwesh Dikshit ◽  
Balasankar Meera Priyadarshini ◽  
Yi Zhang
Keyword(s):  
3D Printing ◽  
Medical Devices ◽  
Three Dimensional ◽  
High Accuracy ◽  
Printing Technology ◽  
Comprehensive Review ◽  
3D Printing Technology ◽  
Wide Range ◽  
Strong Candidate ◽  
Printing Processes

Customized manufacturing of a miniaturized device with micro and mesoscale features is a key requirement of mechanical, electrical, electronic and medical devices. Powder-based 3D-printing processes offer a strong candidate for micromanufacturing due to the wide range of materials, fast production and high accuracy. This study presents a comprehensive review of the powder-based three-dimensional (3D)-printing processes and how these processes impact the creation of devices with micro and mesoscale features. This review also focuses on applications of devices with micro and mesoscale size features that are created by powder-based 3D-printing technology.

scholarly journals A Portable 3D-Printed Platform for Point-of-Care Diagnosis of Clostridium Difficile Infection and Malaria

2019 ◽  
Author(s):  
Soichiro Tsuda ◽  
Lewis A. Fraser ◽  
Salah Sharabi ◽  
Mohammed Hezwani ◽  
Andrew Kinghorn ◽  
...  
Keyword(s):  
Clostridium Difficile ◽  
3D Printing ◽  
Open Source ◽  
Clostridium Difficile Infection ◽  
Point Of Care ◽  
Low Cost ◽  
Clinical Applications ◽  
Printing Technology ◽  
3D Printing Technology ◽  
3D Printed

Here, we integrate 3D-printing technology with low-cost open source electronics to develop a portable diagnostic platform suitable for a wide variety of diagnostic and sensing assays. We demonstrate two different clinical applications in the diagnosis of <i>Clostridium difficile</i> infection and malaria.

scholarly journals Application Status and Prospect of 3D Printing Technology in the Field of Medical Devices

2018 ◽  
Vol 2 (4) ◽  
Author(s):  
Fei Ma
Keyword(s):  
3D Printing ◽  
Medical Devices ◽  
Research Topic ◽  
Printing Technology ◽  
Main Research ◽  
3D Printing Technology ◽  
Main Research Topic ◽  
Manufacturing Science

 3D printing technology belongs to a new manufacturing science and has been widely used in various fields of industry. This article will apply 3D printing technology as its main research topic, with emphasis on its application in the field of medical devices and prospects for contribution.

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