scholarly journals A Portable 3D-Printed Platform for Point-of-Care Diagnosis of Clostridium Difficile Infection and Malaria

2019 ◽  
Author(s):  
Soichiro Tsuda ◽  
Lewis A. Fraser ◽  
Salah Sharabi ◽  
Mohammed Hezwani ◽  
Andrew Kinghorn ◽  
...  

Here, we integrate 3D-printing technology with low-cost open source electronics to develop a portable diagnostic platform suitable for a wide variety of diagnostic and sensing assays. We demonstrate two different clinical applications in the diagnosis of <i>Clostridium difficile</i> infection and malaria.

2019 ◽  
Author(s):  
Soichiro Tsuda ◽  
Lewis A. Fraser ◽  
Salah Sharabi ◽  
Mohammed Hezwani ◽  
Andrew Kinghorn ◽  
...  

Here, we integrate 3D-printing technology with low-cost open source electronics to develop a portable diagnostic platform suitable for a wide variety of diagnostic and sensing assays. We demonstrate two different clinical applications in the diagnosis of <i>Clostridium difficile</i> infection and malaria.


Sensors ◽  
2021 ◽  
Vol 21 (10) ◽  
pp. 3321
Author(s):  
Diogo Helena ◽  
Amélia Ramos ◽  
Tiago Varum ◽  
João N. Matos

With the rise of 5G, Internet of Things (IoT), and networks operating in the mmWave frequencies, a huge growth of connected sensors will be a reality, and high gain antennas will be desired to compensate for the propagation issues, and with low cost, characteristics inherent to metallic radiating structures. 3D printing technology is a possible solution in this way, as it can print an object with high precision at a reduced cost. This paper presents different methods to fabricate typical metal antennas using 3D printing technology. These techniques were applied as an example to pyramidal horn antennas designed for a central frequency of 28 GHz. Two techniques were used to metallize a structure that was printed with polylactic acid (PLA), one with copper tape and other with a conductive spray-paint. A third method consists of printing an antenna completely using a conductive filament. All prototypes combine good results with low production cost. The antenna printed with the conductive filament achieved a better gain than the other structures and showed a larger bandwidth. The analysis recognizes the vast potential of these 3D-printed structures for IoT applications, as an alternative to producing conventional commercial antennas.


Polymers ◽  
2020 ◽  
Vol 12 (11) ◽  
pp. 2492
Author(s):  
Jun Wang ◽  
Bin Yang ◽  
Xiang Lin ◽  
Lei Gao ◽  
Tao Liu ◽  
...  

3D printing technology has been widely used in various fields, such as biomedicine, clothing design, and aerospace, due to its personalized customization, rapid prototyping of complex structures, and low cost. However, the application of 3D printing technology in the field of non-pneumatic tires has not been systematically studied. In this study, we evaluated the application of potential thermoplastic polyurethanes (TPU) materials based on FDM technology in the field of non-pneumatic tires. First, the printing process of TPU material based on fused deposition modeling (FDM) technology was studied through tensile testing and SEM observation. The results show that the optimal 3D printing temperature of the selected TPU material is 210 °C. FDM technology was successfully applied to 3D printed non-pneumatic tires based on TPU material. The study showed that the three-dimensional stiffness of 3D printed non-pneumatic tires is basically 50% of that obtained by simulation. To guarantee the prediction of the performance of 3D printed non-pneumatic tires, we suggest that the performance of these materials should be moderately reduced during the structural design for performance simulation.


2018 ◽  
Vol 919 ◽  
pp. 199-206 ◽  
Author(s):  
Jan Koprnicky ◽  
Jiří Šafka ◽  
Michal Ackermann

The 3D printing technology used for final production of upper limb prostheses is the topicof this article. It focuses on different 3D printing technologies and testing of different thermoplasticmaterials. As the testing object an index finger of HACKberry open source myoelectric bionic handwas used. This part was 3D printed by using of different printing technologies (FFF/FDM, SLA, SLS,PolyJet), and different materials (PLA, ABS, PC-ABS, Though, etc.), and different strategies (heightof layers). The fingers were mechanically tested to simulate flexion in a tip pinch grip. At the endof this paper results of this research and testing is summarized, and optimal material, technology andstrategies of parts production is highlighted.


RSC Advances ◽  
2021 ◽  
Vol 11 (33) ◽  
pp. 20507-20518
Author(s):  
Petr Panuška ◽  
Zuzana Nejedlá ◽  
Jiří Smejkal ◽  
Petr Aubrecht ◽  
Michaela Liegertová ◽  
...  

A novel design of 3D printed zebrafish millifluidic system for embryonic long-term cultivation and toxicity screening has been developed. The chip unit provides 24 cultivation chambers and a selective individual embryo removal functionality.


Molecules ◽  
2021 ◽  
Vol 26 (12) ◽  
pp. 3543
Author(s):  
Wei Zhou ◽  
Jiawei Fang ◽  
Shuwei Tang ◽  
Zhengguo Wu ◽  
Xiaoying Wang

Cushioning and antibacterial packaging are the requirements of the storage and transportation of fruits and vegetables, which are essential for reducing the irreversible quality loss during the process. Herein, the composite of carboxymethyl nanocellulose, glycerin, and acrylamide derivatives acted as the shell and chitosan/AgNPs were immobilized in the core by using coaxial 3D-printing technology. Thus, the 3D-printed cushioning–antibacterial dual-function packaging aerogel with a shell–core structure (CNGA/C–AgNPs) was obtained. The CNGA/C–AgNPs packaging aerogel had good cushioning and resilience performance, and the average compression resilience rate was more than 90%. Although AgNPs was slowly released, CNGA/C–AgNPs packaging aerogel had an obvious antibacterial effect on E. coli and S. aureus. Moreover, the CNGA/C–AgNPs packaging aerogel was biodegradable. Due to the customization capabilities of 3D-printing technology, the prepared packaging aerogel can be adapted to more application scenarios by accurately designing and regulating the microstructure of aerogels, which provides a new idea for the development of food intelligent packaging.


Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Timothy Campbell ◽  
Jonathan Stone ◽  
Arun Parmar ◽  
Edward Vates ◽  
Amrendra Miranpuri

Introduction: While stroke remains a leading cause of death and disability, recent advances in endovascular technology an important opportunity to make a significant impact in clinical outcomes. However, training opportunities are rare, preventing dissemination of these techniques. Hands-on training is further complicated by the critical time to therapy associated with stroke treatment. This physical simulator was built for neurosurgical residents and fellows to practice mechanical thrombectomy. Methods: A simplified virtual model of the anterior cerebral circulation was created based on patient imaging. This luminal model was 3D printed using flexible filament and attached to a guide catheter at the proximal carotid to provide endovascular access and an IV tube at the distal M2 branches to permit outflow. A 7Fr sheath was also connected at the anterior cerebral artery to permit placement of a simulated clot model and simulate a proximal M1 occlusion. This entire construct was placed into a container of polyvinyl alcohol (PVA) and after crosslinking the flexible print was removed. Results: Using 3D printing technology and polymer hydrogels, a low-cost, high fidelity stroke model was achieved. Despite its simplified anatomy, the model permitted realistic wire and catheter navigation through the different segments of the internal carotid and middle cerebral arteries. The ACOM sheath provided a convenient method to reliably place an embolism and created a life-like proximal M1 occlusion. Recanalization was performed using the solumbra technique, which is used in live-patient cases. Conclusions: This model demonstrated proof of concept for a mechanical thrombectomy simulation. The angiographic profile and response to endovascular tools created a training experience similar to live endovascular procedures. As the model is perfected visually and mechanically, next steps are to perform validation studies and create a training curriculum.


Author(s):  
M.A. SEREZHKIN ◽  
D.O. KLIMYUK ◽  
A.I. PLOKHIKH

The article presents the study of the application of 3D printing technology for rapid tooling in sheet metal forming for custom or small–lot manufacturing. The main issue of the usage of 3D printing technology for die tooling was discovered. It is proposed to use the method of mathematical modelling to investigate how the printing parameters affect the compressive strength of FDM 3D–printed parts. Using expert research methods, the printing parameters most strongly affecting the strength of products were identified for further experiments. A method for testing the strength of 3D–printed materials has been developed and tested.


2021 ◽  
pp. 50-54
Author(s):  
Nor Aiman Sukindar ◽  
Noorazizi Mohd Samsuddin ◽  
Sharifah Imihezri Bt. Syed Shaharuddin ◽  
Shafie Kamaruddin ◽  
Ahmad Zahirani Ahmad Azhar ◽  
...  

This project involves the implementation of 3D printing technology on designing and fabricating food holders in the food industry. Food holders are designed to hold the food packages in the filling line for food manufacturing industries that apply retort technology. Therefore, this study aims to implement the 3D printing technology in particular FDM to fabricate food holders for the food processing industry. The approach of using this technology is focused on giving more view on the capability of 3D printing technology, aiming at reducing the overall process fabrication cost and fabrication time. Hence, the fabrication cost and time between FDM and conventional machining methods were compared. This study revealed that Organic Gain food industry was able to reduce the cost and fabrication time for the food holder up to approximately 96.3% and 72% respectively. This project gives an insight into the ability of 3D printing technology in delivering the demands of the industry in producing parts as well as the adaptability of the technology to the industry in new product development. The project was carried out successfully and the 3D printed food holder has been tested and functions smoothly.


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