A reflection on a bone tissue engineering design and commercialisation project

10.26686/wgtn.17148074 ◽

2021 ◽

Author(s):

◽

Thomas Sobiecki

Keyword(s):

Team Building ◽

Technical Information ◽

Advanced Technology ◽

Multiple Goals ◽

Enterprise Development ◽

Engineering Discipline ◽

The Individual ◽

Full Design ◽

Individual Role

<p>A commercialisation project centred round a material called synthetic nacre was undertaken as a teamas part of the 2014 Masters of Advanced Technology Enterprise (MATE) programme. There were multiple goals of: examining the individual role within the group,from an engineering discipline(mechatronics), and what it means for building successful teams; finding and developing the material for a market application, in this casethe niche ofbiodegradable osteoconductive load bearing biomaterials for orthopaedic implants; andreflecting on the personalcontribution to the commercialisation processand how successful it was. The role of an engineer to solve problems was proposed and found to be partially true in this case; additionally a secondary role in communicating technical information coherently was also apparent and important to the enterprise development. An adaptive biomaterial design concept and specification for the target application was formed using the literature and extrapolating where there was no resolution or gaps in the research. The influence of mechatronics has been established on the decision making process and direction of the commercialisation project. The design process was incomplete and therefore the enterprise develop was unsuccessful as it has not been validated by going through a full design, test, evaluate cycle. The goals of the course environment and the team building approach further reinforces this belief.</p>

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Part 6 The Trial: Le Procès, Art.76 Sentencing/Prononcé de la peine

10.1093/law/9780198739777.003.0080 ◽

2016 ◽

Author(s):

Schabas William A

Keyword(s):

International Criminal Court ◽

Rome Statute ◽

International Criminal ◽

Trial Chamber ◽

Criminal Court ◽

Form Part ◽

The Individual ◽

Individual Role

This chapter comments on Article 76 of the Rome Statute of the International Criminal Court. Article 76 governs the imposition of sentence in the event of a conviction. If the accused is convicted, the Trial Chamber is required to establish the ‘appropriate sentence’. In so doing, the Statute instructs it to consider the evidence presented and submissions made during the trial that are relevant to the sentence. Mitigating and aggravating factors relating to the commission of the crime itself, such as the individual role of the offender and of the treatment of the victims, will form part of the evidence germane to guilt or innocence and thus appear as part of the record of the trial.

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Understanding the individual role of fish, oyster, phytoplankton and macroalgae in the ecology of integrated production in earthen ponds

Aquaculture ◽

10.1016/j.aquaculture.2019.734297 ◽

2019 ◽

Vol 512 ◽

pp. 734297 ◽

Cited By ~ 4

Author(s):

M.E. Cunha ◽

H. Quental-Ferreira ◽

A. Parejo ◽

S. Gamito ◽

L. Ribeiro ◽

...

Keyword(s):

Integrated Production ◽

Earthen Ponds ◽

The Individual ◽

Individual Role

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Methodology for assessing the individual role of fish, oyster, phytoplankton and macroalgae in the ecology of integrated production in earthen ponds

MethodsX ◽

10.1016/j.mex.2019.10.016 ◽

2019 ◽

Vol 6 ◽

pp. 2570-2576 ◽

Cited By ~ 1

Author(s):

M.E. Cunha ◽

H. Quental-Ferreira ◽

A. Parejo ◽

S. Gamito ◽

L. Ribeiro ◽

...

Keyword(s):

Integrated Production ◽

Earthen Ponds ◽

The Individual ◽

Individual Role

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The individual role of active sites in bimetallic oxygen evolution reaction catalysts

Dalton Transactions ◽

10.1039/d0dt03448g ◽

2020 ◽

Vol 49 (48) ◽

pp. 17505-17510

Author(s):

Guan-Bo Wang ◽

Chia-Shuo Hsu ◽

Hao Ming Chen

Keyword(s):

Oxygen Evolution ◽

Oxygen Evolution Reaction ◽

Active Sites ◽

Noble Metals ◽

Cost Effective ◽

The Family ◽

The Individual ◽

Individual Role ◽

Bimetallic Oxides

The family of bimetallic oxides, chalcogenides, and pnictides is regarded as a promising and cost-effective oxygen evolution reaction (OER) catalyst compared to noble metals.

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Cable Pili and the 22-Kilodalton Adhesin Are Required for Burkholderia cenocepacia Binding to and Transmigration across the Squamous Epithelium

Infection and Immunity ◽

10.1128/iai.73.9.5426-5437.2005 ◽

2005 ◽

Vol 73 (9) ◽

pp. 5426-5437 ◽

Cited By ~ 32

Author(s):

Teresa A. Urban ◽

Joanna B. Goldberg ◽

Janet F. Forstner ◽

Umadevi S. Sajjan

Keyword(s):

Squamous Epithelium ◽

Burkholderia Cenocepacia ◽

Expression Library ◽

Gene Encoding ◽

Large Gene ◽

Cytokeratin 13 ◽

The Individual ◽

Isogenic Mutants ◽

Individual Role

ABSTRACT Burkholderia cenocepacia strains expressing both cable (Cbl) pili and the 22-kDa adhesin bind to cytokeratin 13 (CK13) strongly and invade squamous epithelium efficiently. It has not been established, however, whether the gene encoding the adhesin is located in the cbl operon or what specific contribution the adhesin and Cbl pili lend to binding and transmigration or invasion capacity of B. cenocepacia. By immunoscreening an expression library of B. cenocepacia isolate BC7, we identified a large gene (adhA) that encodes the 22-kDa adhesin. Isogenic mutants lacking expression of either Cbl pili (cblA or cblS mutants) or the adhesin (adhA mutant) were constructed to assess the individual role of Cbl pili and the adhesin in mediating B. cenocepacia binding to and transmigration across squamous epithelium. Relative to the parent strain, mutants of Cbl pili showed reduced binding (50%) to isolated CK13, while the adhesin mutant showed almost no binding (0 to 8%). Mutants lacking either cable pili or the adhesin were compromised in their ability to bind to and transmigrate across the squamous epithelium compared to the wild-type strain, although this deficiency was most pronounced in the adhA mutant. These results indicate that both Cbl pili and the 22-kDa adhesin are necessary for the optimal binding to CK13 and transmigration properties of B. cenocepacia.

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MUSEUMS – VIEW FROM THE INSIDE

Muzealnictwo ◽

10.5604/01.3001.0010.2669 ◽

2017 ◽

Vol 58 (1) ◽

pp. 0-0

Author(s):

Piotr Kosiewski

Keyword(s):

The People ◽

Museum Professionals ◽

Ethnographic Museums ◽

National Museums ◽

Definition Of ◽

The Individual ◽

University Museum ◽

Maritime Museum ◽

Individual Role

The publication Museums, exhibits, museum professionals complements our knowledge of how museums functioned in the Communist period and their situation after 1989. The book includes discussions or memoirs by eleven people vital to Polish museology, who were connected with National Museums (in Cracow, Poznań and Wrocław), museum-residences (the Wawel Museum, the Royal Castle in Warsaw), specialised museums (the National Maritime Museum in Gdańsk, the Museum of Literature in Warsaw, the Jagiellonian University Museum), ethnographic museums (in Cracow and Toruń) and the Tatra Museum, which is an example of an important regional museum in Poland. Among the people are Zofia Gołubiew, Mariusz Hermansdofer, Jerzy Litwin, Janusz Odrowąż-Pieniążek, Jan Ostrowski, Andrzej Rottermund and Stanisław Waltoś. The book presents the image of Polish museology in a scattershot but interesting way. It also mentions more detailed aspects, such as how particular museums were founded or developed in the Communist period, and the individual role of museum professionals in founding and developing the establishments they managed. However, the most attention is paid to issues regarding the state of museums after 1989. The most important of these include the contemporary functions and tasks of those establishments and the challenges they will face in the future, and the role of a musealium and its place in a contemporary museum. The observations regarding internal changes in museum institutions, in the “master-disciple” relation in the past and today, the appearance of new specialities, and the change of their status and role in institutions (for example, of people responsible for education) are also noteworthy. Another significant thread is the discussion on the definition of a “museum professional” and which museum employees may use this title.

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Unhealthy lifestyles and their deleterious relationship with infections: A Narrative Review

International Journal of Medical and All Body Health Research ◽

10.54660/ijmabhr.2021.2.4.2 ◽

2021 ◽

pp. 54-63

Author(s):

Shashi K Agarwal

Keyword(s):

Health Care Providers ◽

Scientific Literature ◽

Fungal Infections ◽

Narrative Review ◽

Healthy Lifestyles ◽

Direct Connection ◽

Care Providers ◽

The Individual ◽

Individual Role

Infection morbidity and mortality generate a significant global health burden. Several pandemics throughout human history have caused considerable suffering and killed millions of people. The ongoing Covid-19 pandemic is one such example. Individual lifestyles, if healthy, have been shown to modulate immune function and help fight infection. The five most important lifestyles are diet, obesity, exercise, alcohol consumption, and smoking. A favorable lifestyle or a prudent change result in reducing the risk and severity of infections. These include several viral, bacterial, parasitic, and fungal infections. The medical scientific literature is loaded with large well-done studies that have focused on the individual role of these lifestyles. A direct connection has been identified and verified in most cases. This manuscript provides a narrative review of this lifestyle-infection relationship. The aim is to raise the awareness of health care providers on the significant impact healthy lifestyles can have on infectious diseases. It is hoped that disseminating this data will translate into improved healthcare.

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