scholarly journals Research Progress on the Antitumor Effect of Polysaccharides from Fungus Used in Traditional Chinese Medicine

2021 ◽  
Vol 5 (5) ◽  
pp. 7-10
Author(s):  
Ru Xiang ◽  
Bing Xu
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Antitumor Effect ◽  
Biological Activities ◽  
Research Progress ◽  
Cancer Breast ◽  
Wide Range ◽  
Low Toxicity ◽  
Fungal Polysaccharides ◽  
Cancer Côlon

Cancer is a serious threat to human health. Fungal polysaccharide is a polar biological macromolecule with low toxicity. It has a wide range of biological activities, including immune regulation, antitumor activity, and antiviral activity. In recent years, the research results have shown that polysaccharides from fungus in traditional Chinese medicine have excellent antitumor effect in liver cancer, gastric cancer, breast cancer, colon cancer, esophageal cancer, and lung cancer. Therefore, the research and development of fungal polysaccharides are of great significance for the development of antitumor drugs in the future.

scholarly journals Research progress of icariin, an extract of traditional Chinese medicine, in the treatment of asthma

2022 ◽  
Vol 50 (1) ◽  
pp. 9-16
Author(s):  
Jia-ying Yuan ◽  
Zhi-ying Tong ◽  
Yu-chao Dong ◽  
Jia-yi Zhao ◽  
Yan Shang
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Biological Activities ◽  
Airway Disease ◽  
Research Direction ◽  
Research Progress ◽  
Therapeutic Drug ◽  
First Choice ◽  
Wide Range ◽  
New Research

Bronchial asthma is a common chronic airway disease, and long-term management of asthma is the focus and difficulty of clinical treatment. Glucocorticoids are often used as the first choice for the treatment of asthma. However, the occurrence of hormone dependence, hormone resistance, local and systemic adverse reactions caused by hormone application also brings problems for the treatment of asthma. Finding safe and effective new therapeutic drugs is an important research direction at present. Icariin is the effective ingredient of traditional Chinese medicine Epimedium. It has various biological activities such as anti-inflammatory, anti-oxidative stress, and immune regulation. It has high safety and has a wide range of clinical applications. Icariin has the characteristics of multi-target intervention in the treatment of asthma. This article reviews recent studies in order to provide new research directions for further therapeutic drug development.

Medicinal Research Progress of Natural Coumarin and its Derivatives

2020 ◽  
Vol 10 ◽  
Author(s):  
Aadil Khursheed ◽  
Vikrant Jain
Keyword(s):  
Web Of Science ◽  
Biological Activities ◽  
Significant Inhibition ◽  
Research Progress ◽  
Natural Class ◽  
Detailed Review ◽  
Cancer Breast ◽  
Natural Coumarin ◽  
Anti Inflammatory ◽  
Cancer Côlon

Abstract:: Coumarins- a natural class of compounds, firstly isolated from Tonka beans and are found in various medicinal herbs. This class of compounds has been reported of remarkable biological and pharmacological applications including antimicrobial, anticoagulants, anti-inflammatory as well as cancer. Additionally, coumarins have revealed significant inhibition of different human cancers viz bladder cancer, lung cancer, prostate cancer, ovarian cancer, colon cancer, breast cancer, gastric cancer, leukemia, pancreatic cancer and still counting. Therefore, the compilation of medicinal research progress of natural coumarin and its derivatives will be beneficial for scientists and researchers worldwide. The literature review of medicinal research progress of natural coumarin and its derivatives was collected from various databases including PubMed, Web of Science and Science Direct from the year 1942 to date.The presented data on medicinal research progress of natural coumarin and its derivatives provides a detailed review which could serve as a platform for future research.The data presented the medicinal and biological activities of coumarin and its derivatives like antimicrobial, anticoagulant, anti-inflammatory and anticancer in particular. This could be utilized for future formulation and development of drugs and references based on coumarin and its derivatives.

scholarly journals Chemical Constituents of Yarsagumba (Ophiocordyceps sinensis (Berk.) Sung et al.), a Valued Traditional Himalayan Medicine

2013 ◽  
Vol 13 (1) ◽  
pp. 43-58 ◽  
Author(s):  
Sabina Shrestha ◽  
Bhushan Shrestha ◽  
Ji-Hae Park ◽  
Dae-Young Lee ◽  
Jin-Gyeong Cho ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Biological Activities ◽  
Chemical Constituents ◽  
Health Conditions ◽  
Nitrogenous Compounds ◽  
Entomogenous Fungus ◽  
Ophiocordyceps Sinensis ◽  
Wide Range

Ophiocordyceps sinensis (Berk.) Sung et al. is popularly known as Yarsagumba (winter worm summer grass) in Nepal. It is a well-known entomogenous fungus distributed in alpine nival zone of trans-Himalayas and Tibetan Plateau. Its occurrence in extreme biological niche and cohabitation with insect [Thitarodes (Hepialus)] larvae has led to unique assemblage of metabolites including proteins and nitrogenous compounds, polysaccharides, sterols, nucleosides, fatty acids and their derivatives, vitamins and inorganics. In traditional Chinese medicine, it is one of the most trusted main ingredients for several preparations of remedy from wide range of human health conditions. Several biological activities from O. sinensis have been reported that include anti-inflammatory, antioxidant, antitumor, anti-metastatic, immunomodulatory, antimicrobial, insecticidal, hypolipidaemic, hypoglycemic, anti-ageing, lipolytic, neuroprotective, renoprotective effects, etc. The chemical constituents and their pharmacological uses are reviewed here highlighting the potentiality of this highly esteemed traditional Himalayan medicine. Nepal Journal of Science and Technology Vol. 13, No. 1 (2012) 43-58 DOI: http://dx.doi.org/10.3126/njst.v13i1.7398

scholarly journals Research progress in use of traditional Chinese medicine for treatment of spinal cord injury

2020 ◽  
Vol 127 ◽  
pp. 110136 ◽  
Author(s):  
Yubao Lu ◽  
Jingjing Yang ◽  
Xuexi Wang ◽  
Zhanjun Ma ◽  
Sheng Li ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Research Progress ◽  
Cord Injury

Phytochemistry and Pharmacology of the Genus Pedicularis Used in Traditional Chinese Medicine

2014 ◽  
Vol 42 (05) ◽  
pp. 1071-1098 ◽  
Author(s):  
Mao-Xing Li ◽  
Xi-Rui He ◽  
Rui Tao ◽  
Xinyuan Cao
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Chemical Constituents ◽  
Iridoid Glycosides ◽  
In Vivo Studies ◽  
Chemical Components ◽  
Wide Range ◽  
Phenylpropanoid Glycosides

In the present review, the literature data on the chemical constituents and biological investigations of the genus Pedicularis are summarized. Some species of Pedicularis have been widely applied in traditional Chinese medicine. A wide range of chemical components including iridoid glycosides, phenylpropanoid glycosides (PhGs), lignans glycosides, flavonoids, alkaloids and other compounds have been isolated and identified from the genus Pedicularis. In vitro and in vivo studies indicated some monomer compounds and extracts from the genus Pedicularis have been found to possess antitumor, hepatoprotective, anti-oxidative, antihaemolysis, antibacterial activity, fatigue relief of skeletal muscle, nootropic effect and other activities.

scholarly journals Research Progress on Treatment of Abnormal Uterine Bleeding during Puberty with Traditional Chinese and Western Medicine

2021 ◽  
Vol 5 (4) ◽  
pp. 144-147
Author(s):  
Dan Zhang ◽  
Jing Cai ◽  
Xiaoping Cui ◽  
Xinchun Xiao
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Recurrence Rate ◽  
Western Medicine ◽  
Adverse Reactions ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
Research Progress ◽  
Related Literature ◽  
Sudden Collapse

In recent years, the frequency of clinical occurrence of abnormal uterine bleeding in adolescence has gradually increased. In order to fully understand the research progress in the treatment of abnormal uterine bleeding in adolescence, various studies and clinical experience have been reviewed by consulting related literature reports. The results found that currently Western medicine mainly uses hormone drugs in clinical treatment, but there are risks such as more clinical adverse reactions and higher recurrence rate; traditional Chinese medicine (TCM) treatment has achieved satisfactory results, but the advantages of sudden collapse and hemostasis are not obvious. Combined TCM and Western medicine treatment, it can learn from each other and has become a research hotspot in recent years, which is worthy of an in-depth discussion.

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