HISTOLOGICAL CHANGES IN THE SMALL INTESTINE IN THE ADVANCED STAGES OF BURN DISEASE

2017 ◽  
Vol 13 (61) ◽  
pp. 090
Author(s):  
G. M. Galunko
Keyword(s):  
Small Intestine ◽  
Histological Changes ◽  
Advanced Stages ◽  
Burn Disease

scholarly journals Adenocarcinomas of the Intestine Induced in Syrian Hamsters by N-methyl-N-nitrosourea

1969 ◽  
Vol 6 (5) ◽  
pp. 403-412
Author(s):  
Katherine McD. Herrold
Keyword(s):  
Small Intestine ◽  
Cytological Change ◽  
Histological Changes ◽  
Syrian Hamsters ◽  
Histological Types ◽  
Absorptive Cells ◽  
Cytological Features

The adenocarcinomas of the intestine induced in Syrian hamsters by N-methyl-N-nitrosourea (NMU) were of two histological types, superficial and intestinal. These types had distinctive characteristics regarding pattern, cytological features, secretion of mucus, and mode of growth. The histological changes induced by NMU in the mucosa of the small intestine differed from what has been described in enzootic intestinal adenocarcinoma and proliferative ileitis of Syrian hamsters. NMU produced alteration in the villous architecture and cytological change in the absorptive cells. There was marked shortening of the villi and reduced thickness of the mucosa. The villous absorptive cells were large and cuboidal with centrally placed nuclei.

Biochemical and histological changes in the small intestine of mice with dextran sulfate sodium colitis

2011 ◽  
Vol 226 (12) ◽  
pp. 3219-3224 ◽  
Author(s):  
Roger Yazbeck ◽  
Gordon S. Howarth ◽  
Ross N. Butler ◽  
Mark S. Geier ◽  
Catherine A. Abbott
Keyword(s):  
Small Intestine ◽  
Dextran Sulfate ◽  
Dextran Sulfate Sodium ◽  
Histological Changes

scholarly journals Efficacy of oryzalin and associated histological changes in Cryptosporidium-infected neonatal rats

Parasitology ◽  
2002 ◽  
Vol 125 (2) ◽  
pp. 113-117 ◽  
Author(s):  
A. ARMSON ◽  
K. MENON ◽  
A. O'HARA ◽  
L. M. MACDONALD ◽  
C. M. READ ◽  
...  
Keyword(s):  
Small Intestine ◽  
Single Dose ◽  
Neonatal Rats ◽  
Intestinal Villus ◽  
Histological Changes ◽  
Distal Small Intestine ◽  
Maximum Inhibition

This paper reports the anti-cryptosporidial effects of, and concomitant amelioration of the histological changes in the gut of neonatal rats with intestinal cryptosporidiosis treated with the dinitroaniline, oryzalin. The ED50 was determined to be 7 mg/kg using twice daily doses administered for 3 consecutive days. A maximum inhibition of 85.5% was achieved at 25 mg/kg and this inhibition remained constant despite increasing the oryzalin dose to 200 mg/kg. Cryptosporidiosis significantly decreased the intestinal villus/crypt (VC) ratio by approximately 50% (duodenum = 2.3, jejunum = 2.5 and ileum = 1.7) when compared to uninfected untreated controls (duodenum = 4.3, jejunum = 5.9 and ileum = 4.5). Treatment with oryzalin doubled the VC ratio in the duodenum, jejunum and ileum following doses of 5 mg, 50 mg and 200 mg/kg respectively. Oryzalin concentrations in the small intestine contents and plasma were determined, using HPLC, at 0.5, 1 and 2 h after dosing. The much greater dose required to return VC ratios to normal in the ileum (200 mg/kg) compared to the duodenum (6.25 mg/kg) appeared to reflect the decreased concentration of the drug in the distal small intestine. Concentrations of oryzalin equivalent to the in vitro IC50 were maintained for 2 h in the first half of the small intestine following a single dose of 100 mg/kg.

Can Endoscopic Visualization Predict Histological Changes and Early Rejection of Small Intestine Grafts?

2008 ◽  
Vol 103 ◽  
pp. S115
Author(s):  
Ihab El Hajj ◽  
Tong Wu ◽  
Kareem Abu-Elmagd ◽  
Stephen Oʼ Keefe
Keyword(s):  
Small Intestine ◽  
Histological Changes

Histological Changes in the Epithelium of the Small Intestine during Protein Absorption in the New-born Animal

Nature ◽  
1951 ◽  
Vol 168 (4263) ◽  
pp. 84-85 ◽  
Author(s):  
R. S. COMLINE ◽  
H. E. ROBERTS ◽  
D. A. TITCHEN
Keyword(s):  
Small Intestine ◽  
Histological Changes ◽  
Protein Absorption ◽  
New Born

Histological Changes of the Acetabular Labrum in Coxarthrosis: Labral Degeneration and Repair

2016 ◽  
Vol 27 (1) ◽  
pp. 66-73 ◽  
Author(s):  
Marcin E. Domzalski ◽  
Marek Synder ◽  
Anna Karauda ◽  
Wielislaw Papierz
Keyword(s):  
Endothelial Cell ◽  
Cell Formation ◽  
Chondrocyte Apoptosis ◽  
Cellular Infiltration ◽  
Acetabular Labrum ◽  
Histological Changes ◽  
Vascular Proliferation ◽  
Advanced Stages ◽  
Granular Matrix ◽  
The Mean

Introduction The current study was designed to describe types of histological changes within the acetabular labrum in the advanced stages of coxarthrosis, in patients requiring total hip arthroplasty (THA). Methods 77 consecutive patients without systemic disorders or prior hip surgery, scheduled for THA with 3 types of coxarthrosis: avascular necrosis (AVN), idiopathic, and dysplastic coxarthrosis were analysed. Patient's data: age, gender, side of the involvement, duration of the symptoms were recorded, and standard anteroposterior (AP) radiographic views of the pelvis were obtained. During THA procedure the acetabular labrum was harvested and examined histologically and immunohistochemically. The mean chondrocytes number and density were calculated using morphometric techniques. Results In 77 analysed acetabular labra the following histological changes were found: heterogenic matrix, foci of granular matrix breakdown, pseudocysts, intralabral c alcifications, chondrocyte apoptosis, inflammatory reaction with lymphocytes infiltration and macrophages infiltration and vascular proliferation with 2 stages of maturation: endothelial cell formation and fully formed blood vessels. The average chondrocytes density was 478 cells in 1 mm2 and significantly decreased with age. Conclusions The acetabular labrum is an important part of the process of degeneration of the hip in osteoarthritis (OA). Vascular formation and cellular infiltration found in the damaged fibrocartilage may represent a labral response to degenerative changes.

scholarly journals Gambaran histologik usus halus pada hewan coba selama 24 jam postmortem

2017 ◽  
Vol 5 (1) ◽  
Author(s):  
Victori J. Theodore ◽  
Sunny Wangko ◽  
Sonny J.R. Kalangi
Keyword(s):  
Small Intestine ◽  
Observational Study ◽  
Histological Change ◽  
Time Intervals ◽  
Domestic Pig ◽  
Histological Changes

Abstract: Studies about histological changes in small intestine are still very limited. This study was aimed to obtain the histological changes of the small intestine in several time intervals during 24 hours postmortem. This was a descriptive observational study using domestic pig as model. Samples were obtained from the ileum section of the small intestine, taken at 0 hour, 1 hour, 2 hours, 3 hours, 4 hours, 5 hours, 6 hours, 7 hours, 8 hours, 9 hours, 12 hours, 14 hours, 16 hours, 18 hours, 20 hours, 22 hours, and 24 hours postmortem. The results showed that the earliest histological change was identified at 0 hours postmortem as congestion of the intestinal glands and formation of subepithelial cell spaces, followed by destruction of basal membranes of the glands at 3 hours postmortem, lysis of the glands at 16 hours postmortem. At 18-24 hours postmortem, almorst all intestinal glands could not be identified. Conclusion: The earliest histological change of small intestine was identified at 0 hours postmortem as congestion of the intestinal glands, followed by necrosis of the glands at 3 hours postmortem, and lysis of the glands at 16 hours postmortem.Keywords: small intestine, autolysis, histological changes, postmortem Abstrak: Studi mengenai perubahan gambaran histologik usus halus postmortem masih sangat terbatas. Penelitian ini bertujuan untuk mendapatkan gambaran histologik usus halus berdasarkan variasi waktu selama 24 jam postmortem. Jenis penelitian ialah deskriptif observasional dengan menggunakan babi domestik sebagai hewan coba. Sampel diambil dari bagian ileum usus halus pada interval waktu: 0 jam, 1 jam, 2 jam, 3 jam, 4 jam, 5 jam, 6 jam, 7 jam, 8 jam, 9 jam, 12 jam, 14 jam, 16 jam, 18 jam, 20 jam, 22 jam, dan 24 jam postmortem. Hasil penelitian ini memperlihatkan bahwa perubahan histologik usus halus babi mulai teridentifikasi pada 0 jam postmortem berupa kongesti kelenjar intestinal, diikuti oleh kerusakan struktur membran basalis kelenjar pada 3 jam postmortem, dan lisis sel-sel kelenjar pada 16 jam postmortem. Pada 18-24 jam postmortem, hampir seluruh kelenjar intestinal tidak dapat diidentifikasi. Simpulan: Perubahan histologik awal dari usus halus dapat diidentifikasi pada 0 jam postmortem berupa kongesti kelenjar intestinal, diikuti oleh kerusakan struktur membran basalis 3 jam postmortem, dan lisis kelenjar pada 16 jam postmortem. Kata kunci: usus halus, autolisis, postmortem, waktupostmortem, perubahan histologik postmortem

Ultrosonogarphic and histological charac-teristics of the digestive tract in dogs with parvoviral enteritis

2020 ◽  
Vol 1 ◽  
pp. 115-123
Author(s):  
R.A. Tsyganski ◽  
◽  
A.N. Kvochko ◽  
V.V. Mikhailenko ◽  
◽  
...  
Keyword(s):  
Small Intestine ◽  
Chain Reaction ◽  
Histological Changes ◽  
Mucous Layer ◽  
Bowel Diseases ◽  
Inflammatory Bowel ◽  
Polymerase Chain ◽  
Guang Dong ◽  
Number Of Publications ◽  
Ultrasound Parameters

Since the clinical manifestation of enteri-tis of various etiologies has a similar picture, and parvovirus enteritis has a high mortality rate, early diagnosis of this disease is im-portant. A number of publications demon-strate changes in ultrasound parameters dur-ing inflammatory bowel diseases. The article is devoted to comparison of ultrasound and histological changes in the wall of the stom-ach and small intestine with parvovirus en-teritis in order to distinguish the most spe-cific ultrasound markers. Object of the study – 53 dogs of mixed breeds of both sexe with a confirmed diagnosis of parvovirus enteri-tis by polymerase chain reaction in real time from the age of 6 weeks to 7 months. Re-search were conducted at the Stavropol Vet-erinary Center named after Pirogov and Vet-erinary Center of the Stavropol State Agrari-an University, by the use of SIUI Apogee 1100 Omni scanner (Shantou Institute of Ultrasonic Instruments Co., Ltd., Guang-dong, China), according to the generally accepted method using a multi-frequency linear sensor with a frequency of 5-13 MHz in B-mode. The most characteristic ultrason- ic manifestations of canine parvovirus enteri-tis are hypotension and ectasia of the stom-ach and loops of the small intestine with the presence of anechogenic fluid content in their cavity; thickening of the surface layer of the mucosa in the form of a hyperechoic strip, a decrease in the ratio of the mucous layer to the entire wall thickness of the duo-denum and jejunum by more than 2 times and increased echogenicity of the mucous layer. This picture is a result of the partial necrosis and desquamation of villi, prolifera-tion of cell infiltrate in the mucous layer itself, consisting of lymphocytes, macro-phages, a small number of histiocytes and fibroblasts.

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