Meta Analysis: The Effect of Type 2 Diabetes Mellitus in Stroke

ABSTRACT Background: Diabetes can cause pathologic changes in blood vessels at various locations and can lead to stroke if cerebral vessels are directly affected. Additionally, mortality is higher and poststroke outcomes are poorer in patients with stroke with uncontrolled glucose levels. The purpose of this study was to examine the effect of type 2 diabetes mellitus in stroke. Subjects and Method: Meta analysis and systematic review was conducted by collecting published articles from PubMed, Science Direct, Google Sscholar, Mendeley, and Clinical key databases. Keywords used “Diabetes Mellitus” AND “Type 2 Diabetes Mellitus” AND “Stroke” AND “Risk Factor of Stroke” AND “Cross-sectional”. The inclusion criteria were full text and using cross-sectional study design. The articles were collected and selected by PRISMA flow chart. The quantitative data were analyzed by Review Manager 5.3. Results: Meta analysis from 6 studies reported that type 2 DM increased the risk of stroke (aOR= 1.90; 95% CI= 1.41 to 2.57; p<0.001) with heterogeneity (I2= 78%). Conclusion: Type 2 DM increases the risk of stroke. Keywords: type 2 diabetes mellitus, stroke Correspondence: Dody Suprayogi. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: [email protected]. Mobile: 08562772052. DOI: https://doi.org/10.26911/the7thicph.05.46

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The Correlation between the levels of HbA1c with Ureum and Creatinine in Patient with Type 2 Diabetes Mellitus

Asian Journal of Applied Sciences ◽

10.24203/ajas.v7i5.5978 ◽

2019 ◽

Vol 7 (5) ◽

Author(s):

Tri Prasetyorini ◽

Karningsih Sudiro ◽

Bagya Mujianto ◽

Rus Martini

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Chronic Kidney Failure ◽

Cross Sectional Study ◽

Cross Sectional ◽

Glucose Levels ◽

Type 2 Dm ◽

Hba1c Levels

Introduction and Aims : Untransmitted diseases is the leading cause of death globally. Diabetes mellitus is one of the four priorities of untransmitted diseases. This disease is a chronic disease characterized by blood glucose levels that exceed normal values. High blood sugar levels (hyperglycemia) will cause various complications, one of which is chronic complications that can attack various organs such as eyes, kidneys, nerves and blood vessels. This study aims to find out the correlation between the results of the examination of HbA1c, urea and creatinine levels which is an indicator of complications of Chronic Kidney Failure in Type 2 DM patients.Â Methods : This research is a survey research using cross-sectional study design. The respondents in this study are Type 2 DM patients who filled out the questionnaire and examined levels of HbA1c, ureum, and creatinine. Analysis of the data performed by using the SPEARMEN test SPSS for Windows 17.Â Result : The result of the SPEARMEN analysis is p = 0,016 (p < 0.05) which means there is a relationship between the levels of HbA1c with age of respondent. Meanwhile, p = 0,84 (p>0,05) which means there is no relationship between HbA1c levels of type 2 DM with urea levels of type 2 DM patients. While, there is no relationship between HbA1c levels of type 2 DM with creatinine levels of type 2 DM with p = 0.693 (p > 0,05).Â Conclusions : There is a correlation between HbA1c levels of type 2 diabetes mellitus with the age of the respondent, but there is no correlation between HbA1c levels of type 2 diabetes mellitus with ureum levels of type 2 diabetes mellitus and there is no correlation between HbA1c levels with Creatinine levels of Â type 2 diabetes mellitus patients.

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Self-care and clinical parameters in patients with type 2 diabetes mellitus

Rev Rene ◽

10.15253/2175-6783.2015000400004 ◽

2015 ◽

Vol 16 (4) ◽

pp. 479

Author(s):

José Thiago de Sousa ◽

Suyanne Freire de Macêdo ◽

Jayne Ramos Araújo Moura ◽

Ana Roberta Vilarouca da Silva ◽

Eduardo Emanuel Sátiro Vieira ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Self Care ◽

Family Health ◽

Cross Sectional Study ◽

Clinical Parameters ◽

Cross Sectional ◽

Glucose Levels

To verify characteristics related to self-care and clinical parameters in patients with type 2 diabetes mellitus. Methods: descriptive and exploratory, cross-sectional study, conducted with 173 patients assisted in 12 Family Health Units in the urban area of a city in the Northeast region of Brazil. Results: most participants (61.3%) were female, aged less than 60 years old. There were significant differences in the lower glycemic control (p = 0.014), capillary glycemia (p = 0.018) and alcohol consumption (p = 0.015) for men as well as higher central obesity indexes for women (p = 0.000). It was observed high frequency of overweight, abdominal obesity, high blood pressure, elevated blood glucose levels and insufficient levels of physical activity. Conclusion: there is the need for nursing actions aimed at improving self-care and control of the clinical parameters in these patients.

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Glucometers for Patients with Type 2 Diabetes Mellitus: Are they helpful?

International Journal of Medical Students ◽

10.5195/ijms.2021.786 ◽

2021 ◽

Vol 9 (2) ◽

pp. 140-144

Author(s):

Andrew Thomas ◽

Mohan T. Shenoy ◽

K.T. Shenoy ◽

Nirmal George

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Plasma Glucose ◽

Cross Sectional Study ◽

Cross Sectional ◽

Glucose Levels ◽

The Mean ◽

Glycated Hemoglobin Level

Background: The effectiveness of self-monitoring of blood glucose (SMBG) in type 2 diabetes mellitus (T2DM) patients is debated in the literature. We aimed at elucidating the association and patterns of complications between SMBG use and plasma glucose values. Methods: This cross-sectional study comprised 303 participants from outpatient departments with T2DM for over 12 months. We analyzed sociodemographic and clinical variables including: anthropometry, SMBG use, disease duration, treatment modality, complications, plasma glucose level, and glycated hemoglobin level (%). Results: The mean duration of T2DM was 93±76 months. Participants were grouped into SMBG users (n=115, 38%) and non-SMBG users (n=188, 62%). The mean fasting plasma glucose levels of SMBG and non-SMBG users were 140.7±42.7 (95% Confidence Interval [95%CI]: 132.72;148.67) mg/dl and 145.4±50 (95%CI: 138.12;152.67) mg/dl (p=0.03), respectively. The mean post-prandial plasma glucose levels of the SMBG and non-SMBG groups were 202±63.42 (95%CI: 190.23;213.76) mg/dl and 209±84.54 (95%CI: 196.56;221.43) mg/dl (p=0.002), respectively. The mean difference in HbA1c among the groups were 8.14±1.69% (95%CI: 7.59;8.68) and 8.15±1.98% (95%CI: 7.27;9.02) (p=0.4), respectively. Hypoglycemia (n=50, 43.5%) was the most common complication. The prevalence of neuropathy (n=5, 4.3%, p=0.036) and cardiovascular disease (n=21, 18.3%, p=0.042) were significantly higher in the SMBG group. Conclusion: Although plasma glucose values were significantly lower in the SMBG group, its clinical significance remains questionable. Furthermore, many participants in both the groups had shortfalls in awareness, monitoring, and glycemic control. SMBG use needs to be evaluated in a cohort of patients with T2DM with adequate health awareness.

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The Effect of Insulin Provision on the Risk Reduction of Type 2 Diabetes Mellitus: Meta-Analysis

Childhood Stunting, Wasting, and Obesity, as the Critical Global Health Issues: Forging Cross-Sectoral Solutions ◽

10.26911/the7thicph.05.49 ◽

2020 ◽

Author(s):

Dian Dini Islami ◽

◽

Didik Gunawan Tamtomo ◽

Hanung Prasetya ◽

◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Risk Reduction ◽

Meta Analysis ◽

Cellular Transport ◽

Cross Sectional ◽

Fed State ◽

Central Java

ABSTRACT Background: Insulin is the pivotal hormone regulating cellular energy supply and macronutrient balance, directing anabolic processes of the fed state. Insulin is essential for the intra-cellular transport of glucose into insulin-dependent tissues such as muscle and adipose tissue. The purpose of this study was to examine the effect of insulin provision on the risk reduction of type 2 diabetes mellitus. Subjects and Method: This was meta-analysis and systematic review. The study was conducted by collecting articles from PubMed, Google Scholar, and Springer Link databases, from 2010-2020. Keywords used “effect insulin” OR “giving insulin” AND “diabetes mellitus” OR “diabetes” AND “cross sectional” AND “adjusted odd ratio”. The inclusion criteria were full text, using English or Indonesia language, and using crosssectional study design. The articles were selected by PRISMA flow chart. The quantitative data were analyzed by RevMan 5.3. Results: A meta-analysis from 5 studies in Ethiopia, Northeast Ethiopia, Taiwan, African American, and South Korea, reported that insulin provision reduced the risk of diabetes mellitus (aOR= 1.89; 95% CI= 1.82 to 3.57; p= 0.05) with I2= 84%. Conclusion: Insulin provision reduced the risk of diabetes mellitus. Keywords: insulin, type 2 diabetes mellitus Correspondence: Dian Dini Islami. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: [email protected]. Mobile: 085729483960. DOI: https://doi.org/10.26911/the7thicph.05.49

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Consumption of Dairy Products in Relation to Type 2 Diabetes Mellitus in Chinese People: The Henan Rural Cohort Study and an Updated Meta-Analysis

Nutrients ◽

10.3390/nu12123827 ◽

2020 ◽

Vol 12 (12) ◽

pp. 3827

Author(s):

Mengying Fan ◽

Yuqian Li ◽

Chongjian Wang ◽

Zhenxing Mao ◽

Lulu Zhang ◽

...

Keyword(s):

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Type 2 Diabetes Mellitus ◽

Meta Analysis ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Dairy Intake ◽

Dairy Consumption

Recent studies on whether dairy consumption is associated with type 2 diabetes mellitus (T2DM) have yielded inconsistent results, so we explored the relationship between dairy consumption and T2DM through a large-sample, cross-sectional study and a meta-analysis. In the meta-analysis, summary relative risks (RRs) of 23 articles were compiled with a random effects model, and a restricted cubic spline regression model was used to explore whether there is a nonlinear relationship between dairy intake and T2DM risk. This cross-sectional study used baseline data from 38,735 participants of the Henan Rural Cohort study and the association between dairy consumption and T2DM was analyzed by a logistic regression model. The meta-analysis revealed a borderline negative significant association between total dairy intake and risk of T2DM, the RR and 95% confidence interval (CI) was 0.94; (0.89, 1.00), and the risk was lowest at 270 g daily dairy intake. In the cross-sectional study, there were 3654 T2DM patients and 68.3 percent of the respondents had no dairy intake. The average intake of dairy in the total population was 12 g per day. Fully adjusted analyses suggested positive associations, with an odds ratio (OR) comparing the highest with the zero intake of 1.34 (95% CI: 1.22, 1.48) for all participants, which was unaffected by sex. Dairy intake in rural areas of Henan province is low, and we found, in the context of overall low dairy intake, that a high intake was positively associated with T2DM, which is inconsistent with the meta-analysis results suggesting that dairy has marginal protective effects against T2DM.

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The Effect of Depression Comorbidity on the Quality of Life of Patients with Type 2 Diabetes Mellitus: Meta-Analysis

Childhood Stunting, Wasting, and Obesity, as the Critical Global Health Issues: Forging Cross-Sectoral Solutions ◽

10.26911/the7thicph.01.56 ◽

2020 ◽

Author(s):

Rofana Aghniya ◽

◽

Bhisma Murti ◽

Didik Gunawan Tamtomo ◽

Hanung Prasetya ◽

...

Keyword(s):

Quality Of Life ◽

Diabetes Mellitus ◽

Type 2 Diabetes ◽

Meta Analysis ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Type 2 Dm

Background: The prevalence of depression is two to three times higher in diabetic patients, while most cases remain undiagnosed. The quality of life is substantially and adversely affected by depression. This study aimed to estimate the effect of depression comorbidity on patients’ quality of life with type 2 diabetes mellitus. Subjects and Method: This was a meta-analysis and systematic review. The study was conducted by collecting published articles from PubMed, ProQuest, Science Direct, Scopus, Spinger Link, Clinical Key, and Google Scholar databases. Keywords used “comorbidity depression and DM”, “depression and quality of life and DM and cross sectional study”, “depression and quality of life and DM and adjusted odd ratio”, “depression or diabetes”, “depression or quality of life or DM or adjusted odd ratio”. The study criteria were full text, using cross-sectional study design, and reporting adjusted Odds Ratio (aOR). The selected articles were analyzed using Revman 5.3 with fixed effect models. Results: 8 studies from Uganda, Iran, United States, United Kingdom, Australia, Nigeria, Brazil, and Nepal, were selected for this study. Current study reported that type 2 DM patients with depression had lower quality of life than those without depression (aOR= 2.72; 95% CI= 0.73 to 10.07; p<0.0001) Conclusion: Type 2 DM patient with depression has lower quality of life than those without depression. Keywords: depression, quality of life, diabetes mellitus Correspondence: Rofana Aghniya. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutami 36A, Surakarta 57126, Central Java. Email: [email protected]. Mobile: +685523528340.

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