scholarly journals European public health policies for managing contacts of invasive meningococcal disease cases better harmonised in 2013 than in 2007

2016 ◽  
Vol 21 (5) ◽  
Author(s):  
Sabine Vygen ◽  
Wiebke Hellenbrand ◽  
Pawel Stefanoff ◽  
Germaine Hanquet ◽  
Sigrid Heuberger ◽  
...  

In 2007, a European survey identified variation in country policies on public health management of invasive meningococcal disease (IMD). In 2009–10, the European Centre for Disease Prevention and Control (ECDC) published evidence-based guidance on IMD. We therefore surveyed again European countries to describe policies for managing IMD cases and contacts in 2013. We asked national IMD public health experts from 32 European countries to complete a questionnaire focusing on post-exposure prophylaxis (PEP) for IMD contacts and meningococcal vaccination. Proportions in 2007 and 2013 were compared using the chi-squared test. All 32 countries responded, with responses from two regions for Belgium and Italy; half stated having used ECDC guidance to update national recommendations. PEP was recommended to close contacts in 33 of 34 countries/regions, mainly ciprofloxacin for adults (29/32 countries) and rifampicin for children (29/32 countries). ECDC guidance for managing IMD contacts in airplanes was strictly followed by five countries/regions. Twenty-three countries/regions participated in both surveys. Compared with 2007, in 2013, more countries/regions recommended i) ceftriaxone for children (15/23 vs 6/20; p = 0.03), ii) PEP for all children in the same preschool group (8/23 vs 17/23; p = 0.02). More countries/regions recommended evidence-based measures for IMD public health management in 2013 than 2007. However, some discrepancies remain and they call for further harmonisation.

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
A Miglietta

Abstract During 2015-2016 an outbreak of invasive meningococcal disease due to Neisseria meningitidis serogroup C ST-11 (cc11) occurred in Tuscany, a Region in Central Italy. Sixty-two cases with 13 deaths (13%) were recorded. Regional Authorities responded through a mass immunization campaign targeting all the age groups by offering free of charge a single dose of the tetravalent (ACWY) meningococcal conjugate vaccine or monovalent meningococcal C conjugate (MCC) vaccine. Nevertheless, the response was fragmented and the campaign did not reach the risk-population groups (i.e. men who have sex with men), that were identified only when a Regional outbreak investigation was implemented. Also linkage between cases (i.e. attending the same gay-venue) were identified at a second stage, not allowing prompt max-prophylaxis interventions. In such a situation, an evidence-based approach as Health Technology Assessment, could have informed public health emergency preparedness and response planning processes, i.e. by identifying through early warning alert systems similar ongoing clusters in Europe among specific population-groups and consequently better targeting the immunization campaign. The objective of this presentation is to explore through a practical example how HTA could provide an evidence-based approach for public health response during a real outbreak underlining lesson learned.


2008 ◽  
Vol 13 (45) ◽  
Author(s):  
I Zuschneid ◽  
A Witschi ◽  
L Quaback ◽  
W Hellenbrand ◽  
N Kleinkauf ◽  
...  

Following the fatal invasive meningococcal disease in a Swiss student who had been visiting Berlin, several public health institutions on local, regional and national level cooperated to ensure that the appropriate measures such as contact tracing and post exposure prophylaxis were taken to prevent further cases. The incidence highlighted the importance of early disease notification and showed that if an infectious disease requiring public health action occurs in an international context, it is vital that relevant information is communicated to all levels of the public health systems of the countries involved.


1992 ◽  
Vol 25 (3) ◽  
pp. 321-328 ◽  
Author(s):  
S.R. Palmer ◽  
J. Corson ◽  
R. Hall ◽  
S. Payne ◽  
J. Ludlow ◽  
...  

2002 ◽  
Vol 6 (45) ◽  
Author(s):  
E Hoile

New, revised guidelines for the public health management of meningococcal disease have been published in the United Kingdom, as a result of recent changes in the epidemiology of meningococcal disease together with the introduction of new vaccines and an accumulation of new evidence on risk evaluation and control methods (1). The guidelines cover pre-admission management, investigation of suspect cases, the role of public health, public health action after a single case, prophylaxis in healthcare settings and the management of clusters. The guidance contains detailed revisions on the use of antibiotics before admission to hospital, the rationale and indications for chemoprophylaxis, and the use of new vaccines. All recommendations within the review are graded according to the level of evidence on which they are based, probably the first European guidelines to do so (2).


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