scholarly journals Impact of infectious diseases on population health using incidence-based disability-adjusted life years (DALYs): results from the Burden of Communicable Diseases in Europe study, European Union and European Economic Area countries, 2009 to 2013

2018 ◽  
Vol 23 (16) ◽  
Author(s):  
Alessandro Cassini ◽  
Edoardo Colzani ◽  
Alessandro Pini ◽  
Marie-Josee J Mangen ◽  
Dietrich Plass ◽  
...  
Keyword(s):  
Infectious Disease ◽  
Prevention And Control ◽  
Data Availability ◽  
European Economic Area ◽  
Disability Adjusted Life Years ◽  
Economic Area ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Total Burden ◽  
And Control

Background and aims The Burden of Communicable Diseases in Europe (BCoDE) study aimed to calculate disability-adjusted life years (DALYs) for 31 selected diseases in the European Union (EU) and European Economic Area (EEA). Methods: DALYs were estimated using an incidence-based and pathogen-based approach. Incidence was estimated through assessment of data availability and quality, and a correction was applied for under-estimation. Calculation of DALYs was performed with the BCoDE software toolkit without applying time discounting and age-weighting. Results: We estimated that one in 14 inhabitants experienced an infectious disease episode for a total burden of 1.38 million DALYs (95% uncertainty interval (UI): 1.25–1.5) between 2009 and 2013; 76% of which was related to the acute phase of the infection and its short-term complications. Influenza had the highest burden (30% of the total burden), followed by tuberculosis, human immunodeficiency virus (HIV) infection/AIDS and invasive pneumococcal disease (IPD). Men had the highest burden measured in DALYs (60% of the total), adults 65 years of age and over had 24% and children less than 5 years of age had 11%. Age group-specific burden showed that infants (less than 1 year of age) and elderly people (80 years of age and over) experienced the highest burden. Conclusions: These results provide baseline estimates for evaluating infectious disease prevention and control strategies. The study promotes an evidence-based approach to describing population health and assessing surveillance data availability and quality, and provides information for the planning and prioritisation of limited resources in infectious disease prevention and control.

scholarly journals Burden of Healthcare-Associated Infections in Italy: Disability-Adjusted Life Years

2020 ◽  
Vol 30 (Supplement_5) ◽  
Author(s):  
V Bordino ◽  
C Vicentini ◽  
A D'Ambrosio ◽  
F Quattrocolo ◽  
C M Zotti
Keyword(s):  
Prevention And Control ◽  
Infection Prevention And Control ◽  
Healthcare Associated Infections ◽  
Disability Adjusted Life Years ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Significant Burden ◽  
Tract Infections ◽  
Healthcare Associated ◽  
And Control

Abstract Background Healthcare-Associated Infections (HAIs) significantly increase adverse clinical outcomes and healthcare costs. In 2016 Italy participated in the second European Centre for Disease Prevention and Control (ECDC) Point Prevalence Survey (PPS) of HAIs and antimicrobial use in acute care hospitals. The aim of this study was to estimate the burden of the 5 most common HAIs in Italy, by evaluating incidence, attributable deaths, Years of Life Lost (YLL), Years Lived with Disability (YLD) and Disability-Adjusted Life-Years (DALYs). Methods National PPS data were used to establish sex- and age-specific incidence of Healthcare-associated Pneumonia (HAP), HA Urinary tract infections (HA UTI), HA Bloodstream Infections (HA BSI) excluding neonatal BSI, Surgical Site Infections (SSI), HA Clostridium Difficile infections (HA CDI). Patients' life expectancy was adjusted according to the severity of underlying conditions using the McCabe score. Following the methodology from the Burden of Communicable Diseases in Europe (BCoDE)-project, an adapted version of the disease models of the BCoDE toolkit was used. Results An overall yearly incidence of 643434 new cases of HAI in Italy was estimated. The aggregate burden of the 5 HAIs was 426411.98 DALYs (86731.03 YLD + 339680.96 YLL), corresponding to 702.53 DALYs per 100000 total population. HA BSI and HAP had the highest burden with respectively 253868.22? and 126038.26 DALYs. The population strata with the highest burden were the ones with McCabe Score 1 for every considered HAI. The age groups with the highest burden were 70-74 for male and 45-49 for female patients. In total, 56% of DALYs were attributable to men and 44% to women. Conclusions This nation-wide study found a significant burden of disease due to HAIs in Italy. Results of this study could be used to guide policy-makers in the implementation of measures aiming to reduce the impact of HAIs. Key messages This study estimated the burden of 5 HAIs in Italy was 426411.98 DALYs (86731.03 YLD + 339680.96 YLL according to 2016 PPS data. Considering the significant burden of HAIs found in this study, infection prevention and control measures should be a Public Health priority in Italy.

scholarly journals High Blood Pressure prevention and control: from evidence to action

2018 ◽  
Vol 49 (2) ◽  
pp. 137-138
Author(s):  
Lena Barrera
Keyword(s):  
Blood Pressure ◽  
High Blood Pressure ◽  
Latin American ◽  
Prevention And Control ◽  
National Health Survey ◽  
Middle Income ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Health Organization ◽  
And Control

The Pan American Health Organization (PAHO) with the World Hypertension League has established the 17th May to promote the prevention and control of High Blood Pressure (HBP). Currently nearly 1.13 billion of adults suffer from HBP (blood pressure ≥140/90 mm Hg) worldwide. While HBP prevalence decreased in high income countries (HIC) between 1975 and 2015, the opposite trend was observed in low- and middle- income countries (LMIC). Particularly, in Latin American and Caribbean countries the prevalence decreased from 40.6% to 26.8% and from 26.8% to 19.4% for men and women between 45 to 49 years old respectively. However, in 2015, HBP accounted for 8.9 of the total of disability adjusted life years (DALYS) and was associated with 4.9 million, 2.0 million and 1.5 million deaths due to ischemic heart disease, hemorrhagic stroke and ischemic stroke respectively. Therefore, HBP is the leading cardiovascular risk factor worldwide. In Colombia, the last National Health Survey reported a global prevalence of 22.8% and nearly 60% for those between 60 and 69 years in 2007

scholarly journals Estimation of Burden of Cystic Echinococcosis in Iran Using Disability Adjusted Life Years (DALYs) in 2018

2021 ◽  
Author(s):  
Fateme Parandin ◽  
Fatemeh Heydarpour ◽  
Mehdi Mohebali ◽  
Ahmad Ali Hanafi-Bojd ◽  
Ali Akbari Sari ◽  
...  
Keyword(s):  
Premature Death ◽  
Years Of Life Lost ◽  
Disability Adjusted Life Years ◽  
Public Concern ◽  
Policy Makers ◽  
Control Programs ◽  
Disability Adjusted Life ◽  
Life Years ◽  
Standard Life ◽  
And Control

Background: Human hydatidosis as a public concern has increased in a number of countries that have reduced control programs for the disease due to lack of resources or policies. We aimed to estimate Disability-Adjusted Life Years (DALYs) for human hydatidosis in Iran in 2018. Methods: Data were collected from the Center of Communicable Diseases Control, Ministry of Health &Medical Education, Tehran, Iran in 2018. To calculate DALYs, years of life lost due to premature death (YLL) with years of life with disability (YLD) were calculated according to the formula as DALY = YLL + YLD. The standard life expectancy lost method (SEYLL) was used to calculate the years lost due to premature death. Results: DALYs for human hydatidosis was calculated as 1210.12 years (YLD equals to 177.12 and YLL equals to 1033) in Iran for the year 2018. It was estimated to be 700.2 years for men and 509.8 years for women.  DALYs in men were significantly different from women (P= 0.001) so DALYs were more in men than women were. YLD was calculated at 78.228 years in men and 98.892 years in women and in both men and women at 177.12 years. YLD was significantly different in women compared to men (P=0.001), so YLD in women was more than in men. Conclusion: We reached considerable indices for hydatidosis in our study. Therefore, disease prevention and control programs in Iran seem necessary by the policy makers.

Injury prevention and control

2021 ◽  
pp. 361-376
Author(s):  
Corinne Peek-Asa ◽  
Adnan A. Hyder
Keyword(s):  
Injury Prevention ◽  
Low Income ◽  
Prevention And Control ◽  
Low Income Countries ◽  
Middle Income ◽  
Injury Rates ◽  
Middle Income Countries ◽  
Disability Adjusted Life ◽  
Life Years ◽  
And Control

Injuries are among the leading causes of death and disability throughout the world and contribute disproportionately to premature life lost. Injury rates are highest among middle- and low-income countries. According to analyses of the 2016 Global Burden of Disease data, injuries cause over 4.6 million deaths per year, accounting for nearly 8.4% of all deaths and 10.7% of disability-adjusted life years. Many opportunities to implement injury prevention strategies exist, and a systematic approach to injury prevention can help identify the most effective and efficient approaches. Building capacity for injury prevention activities in low- and middle-income countries is an important public health priority.

scholarly journals ASSOCIATION BETWEEN CERTAIN DEMOGRAPHIC INDEXES AND THE NUMBER OF CLINICAL TRIALS IN THE EUROPEAN ECONOMIC AREA

2021 ◽  
Vol 27 (1) ◽  
pp. 3619-3623
Author(s):  
Liliya Bogdanova ◽  
◽  
Valentina Belcheva ◽  
Evgeni Grigorov ◽  
◽  
...  
Keyword(s):  
Clinical Trial ◽  
Clinical Trials ◽  
Life Expectancy ◽  
Demographic Factors ◽  
European Economic Area ◽  
European Economic ◽  
Trial Conduct ◽  
Economic Area ◽  
Disability Adjusted Life ◽  
Life Years

Purpose: The number of clinical trials conducted by the industry has increased significantly for the period 2014-2016. They have produced advances in disease prevention, treatment, and rehabilitation for many diseases. This was the main reason to carry a study on the association between certain demographic indexes and the number of clinical trials in the European economic area. Proving a correlation between those two variables could lead to additional research pursued by the industry during the feasibility phase of each study in order to have higher and quicker enrollment for the success of the clinical trial. Materials/Methods: Three demographic factors were considered to have some importance on the clinical trial enrollment – the number of population, life expectancy at age 65 and Disability-Adjusted Life Years (DALY). The numbers were processed with Spearman‘rho, and the read of the results shows a correlation to be present for the number of population and life expectancy at age 65. Results: There is a correlation between the number of clinical trials opened for enrollment of patients and certain demographic indexes, which could lead to favorable conditions for trial conduct in the different countries of EEA. Conclusions: Studying in advance if some demographic factors are significant for conduct of clinical studies is something new that could be used by the industry to avoid the wastefulness of a clinical project.

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