scholarly journals Highly pathogenic avian influenza (HPAI) outbreaks, South East Asia: WHO response

2004 ◽  
Vol 8 (29) ◽  
Author(s):  

Two press releases from the World Health Organization (WHO) last week have refocused international attention on highly pathogenic avian influenza (HPAI) A(H5N1)

2006 ◽  
Vol 11 (51) ◽  
Author(s):  
Collective Influenza team (ECDC)

As of 29 November 2006, 258 human H5N1 infections that meet its strict laboratory criteria have been reported to the World Health Organization (WHO) since reporting began for 2003


2004 ◽  
Vol 8 (6) ◽  
Author(s):  

The Ministry of Health in Vietnam and the World Health Organization (WHO) have confirmed three new cases of highly pathogenic avian influenza (HPAI) A H5N1 in humans.


2019 ◽  
Vol 4 (4) ◽  
pp. 138 ◽  
Author(s):  
Chowdhury ◽  
Hossain ◽  
Ghosh ◽  
Ghosh ◽  
Hossain ◽  
...  

Highly pathogenic avian influenza (HPAI) H5N1 has caused severe illnesses in poultry and in humans. More than 15,000 outbreaks in domestic birds from 2005 to 2018 and 861 human cases from 2003 to 2019 were reported across the world to OIE (Office International des Epizooties) and WHO (World Health Organization), respectively. We reviewed and summarized the spatial and temporal distribution of HPAI outbreaks in South Asia. During January 2006 to June 2019, a total of 1063 H5N1 outbreaks in birds and 12 human cases for H5N1 infection were reported to OIE and WHO, respectively. H5N1 outbreaks were detected more in the winter season than the summer season (RR 5.11, 95% CI: 4.28–6.1). Commercial poultry were three times more likely to be infected with H5N1 than backyard poultry (RR 3.47, 95% CI: 2.99–4.01). The highest number of H5N1 outbreaks was reported in 2008, and the smallest numbers were reported in 2014 and 2015. Multiple subtypes of avian influenza viruses and multiple clades of H5N1 virus were detected. Early detection and reporting of HPAI viruses are needed to control and eliminate HPAI in South Asia.


2004 ◽  
Vol 8 (5) ◽  
Author(s):  
Collective Editorial team

There are currently widespread outbreaks of Highly Pathogenic Avian Influenza (HPAI) in South East Asia that have been ongoing since late 2003. The outbreaks are due to a strain of influenza A, subtype H5N1.


BMC Medicine ◽  
2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Xinhua Chen ◽  
Wei Wang ◽  
Yan Wang ◽  
Shengjie Lai ◽  
Juan Yang ◽  
...  

Abstract Background Highly pathogenic avian influenza A(H5N1) virus poses a global public health threat given severe and fatal zoonotic infections since 1997 and ongoing A(H5N1) virus circulation among poultry in several countries. A comprehensive assessment of the seroprevalence of A(H5N1) virus antibodies remains a gap and limits understanding of the true risk of A(H5N1) virus infection. Methods We conducted a systematic review and meta-analysis of published serosurveys to assess the risk of subclinical and clinically mild A(H5N1) virus infections. We assessed A(H5N1) virus antibody titers and changes in titers among populations with variable exposures to different A(H5N1) viruses. Results Across studies using the World Health Organization-recommended seropositive definition, the point estimates of the seroprevalence of A(H5N1) virus-specific antibodies were higher in poultry-exposed populations (range 0–0.6%) and persons exposed to both human A(H5N1) cases and infected birds (range 0.4–1.8%) than in close contacts of A(H5N1) cases or the general population (none to very low frequencies). Seroprevalence was higher in persons exposed to A(H5N1) clade 0 virus (1.9%, range 0.7–3.2%) than in participants exposed to other clades of A(H5N1) virus (range 0–0.5%) (p < 0.05). Seroprevalence was higher in poultry-exposed populations (range 0–1.9%) if such studies utilized antigenically similar A(H5N1) virus antigens in assays to A(H5N1) viruses circulating among poultry. Conclusions These low seroprevalences suggest that subclinical and clinically mild human A(H5N1) virus infections are uncommon. Standardized serological survey and laboratory methods are needed to fully understand the extent and risk of human A(H5N1) virus infections.


2005 ◽  
Vol 10 (3) ◽  
Author(s):  
C S Brown ◽  
W J Paget ◽  
A Meijer

Poultry outbreaks and human cases of infection with highly pathogenic avian influenza virus A(H5N1) continue to be documented in Asia, with several new human infections being reported since December 2004, following a period of 2 months when no cases were reported.


2006 ◽  
Vol 11 (6) ◽  
Author(s):  
Collective Editorial team

Highly pathogenic H5N1 avian influenza has been detected in poultry in northern Nigeria, according to the World Organisation for Animal Health (OIE) and the World Health Organization


Author(s):  
M. A. Sapachova ◽  
M. I. Sushko ◽  
S. S. Mandyhra ◽  
O. M. Movchun ◽  
A. O. Skorokhod ◽  
...  

The aim of the work was to analyze current epidemic situation on highly pathogenic avian influenza worldwide and in Ukraine during 2019–2020. The research was conducted in the framework of state control of infectious animal diseases. The results of PCR tests obtained in the State Scientific and Research Institute of Laboratory Diagnostics and Veterinary and Sanitary Expertise and in regional state laboratories, data of OIE website (http://www.oie.int) in 2019 and 2020 were analyzed and summarized. During 2019–2020 outbreaks of highly pathogenic avian influenza were detected in 53 countries of the World: in Europe — 22, in Asia — 21, in Africa — 7, in America — 2, and in Australia — 1. In 2019 there was not registered any case of the highly pathogenic avian influenza in Ukraine. In 2020 nine outbreaks of avian influenza were registered in commercial poultry farms (n = 2) and backyards (n = 7) of Vinnytsia, Mykolaiv, Kyiv, and Kherson regions of Ukraine. It was confirmed that all characterized viruses were closely related and belonged to the highly pathogenic avian influenza virus H5N8 clade 2.3.4.4b identical to the avian influenza viruses currently circulating in Europe and Asia. Wild birds were identified as the main modes of HPAIV spread


2005 ◽  
Vol 10 (32) ◽  
Author(s):  
M Cooke ◽  
J Van-Tam

The highly pathogenic avian influenza A (H5N1) virus which is causing influenza outbreaks in South East Asia represents the most plausible candidate for a pandemic human influenza strain since the last influenza pandemic in 1968


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