scholarly journals A Mini Review on SARS-COVID-19-2 Omicron Variant (B.1.1.529)

2021 ◽  
Vol 3 (4) ◽  
pp. 399-406
Author(s):  
Santhosh Kumar Ettaboina ◽  
Komalatha Nakkala ◽  
K. S. Laddha
Keyword(s):  
South Africa ◽  
Protein Structure ◽  
Genetic Code ◽  
Full Text ◽  
Essential Role ◽  
Lung Infection ◽  
Current Paper ◽  
Genome Replication ◽  
New Variant ◽  
Need To Evaluate

The current world facing unpredictable problems with different variants of COVID-19; SARS-COV-19 is a significant lung infection caused by a coronavirus. Each type has one or more alterations to distinguish from each other. The viruses, including SARS-COV-19, continuously change the genetic code (mutations) during their genome replication. WHO labelled two variants in that we are experienced with delta (B.1.617.2) variant, now recently the omicron came (B.1.1.529) with highly mutatable strikes on it. So WHO predicted it is more dangerous than previous variants because of its mutatable capability. The mutatable strikes play an essential role in transmissibility. So there is a need to evaluate threatens raised with the new variant, so scientists are working on it. Till now, South Africa noticed major cases positive for the Omicron variant. Based on recent reports, the current paper summarized different properties of the omicron variant with others, including protein structure, diagnosis, spreadability, treatment, and potency of vaccines. Doi: 10.28991/SciMedJ-2021-0304-10 Full Text: PDF

scholarly journals The Impact on Infectivity and Neutralization Efficiency of SARS-CoV-2 Lineage B.1.351 Pseudovirus

Viruses ◽  
2021 ◽  
Vol 13 (4) ◽  
pp. 633
Author(s):  
Yeong Jun Kim ◽  
Ui Soon Jang ◽  
Sandrine M. Soh ◽  
Joo-Youn Lee ◽  
Hye-Ra Lee
Keyword(s):  
South Africa ◽  
Monoclonal Antibodies ◽  
Cell Fusion ◽  
Receptor Binding ◽  
Neutralizing Antibodies ◽  
Receptor Binding Domain ◽  
Viral Spread ◽  
New Variant ◽  
Global Concern ◽  
The Impact

A new variant of SARS-CoV-2 B.1.351 lineage (first found in South Africa) has been raising global concern due to its harboring of multiple mutations in the spike that potentially increase transmissibility and yield resistance to neutralizing antibodies. We here tested infectivity and neutralization efficiency of SARS-CoV-2 spike pseudoviruses bearing particular mutations of the receptor-binding domain (RBD) derived either from the Wuhan strains (referred to as D614G or with other sites) or the B.1.351 lineage (referred to as N501Y, K417N, and E484K). The three different pseudoviruses B.1.351 lineage related significantly increased infectivity compared with other mutants that indicated Wuhan strains. Interestingly, K417N and E484K mutations dramatically enhanced cell–cell fusion than N501Y even though their infectivity were similar, suggesting that K417N and E484K mutations harboring SARS-CoV-2 variant might be more transmissible than N501Y mutation containing SARS-CoV-2 variant. We also investigated the efficacy of two different monoclonal antibodies, Casirivimab and Imdevimab that neutralized SARS-CoV-2, against several kinds of pseudoviruses which indicated Wuhan or B.1.351 lineage. Remarkably, Imdevimab effectively neutralized B.1.351 lineage pseudoviruses containing N501Y, K417N, and E484K mutations, while Casirivimab partially affected them. Overall, our results underscore the importance of B.1.351 lineage SARS-CoV-2 in the viral spread and its implication for antibody efficacy.

scholarly journals Perceptions on physiopathology and preferred treatment of epilepsy and asthma in the Limpopo Province, South Africa

2003 ◽  
Vol 8 (1) ◽  
Author(s):  
Supa Promtussananon
Keyword(s):  
South Africa ◽  
Risk Reduction ◽  
Full Text ◽  
Limpopo Province ◽  
Treatment Of Epilepsy

The objectives of this study were to analyse perceptions of epilepsy and asthma, due to attribution of cause, suggested means of risk reduction and preferred treatment. Opsomming Die doelwitte van hierdie studie was om persepsies van epilepsie en asma te analiseer na aanleiding van die toeskrywing van oorsaak, voorgestelde metodes van risikovermindering en verkose behandeling. *Please note: This is a reduced version of the abstract. Please refer to PDF for full text.

scholarly journals Factors affecting behaviours that address HIV risk among a sample of junior secondary school students in the Northern Province, South Africa

2002 ◽  
Vol 7 (3) ◽  
Author(s):  
Karl Peltzer
Keyword(s):  
South Africa ◽  
Secondary School ◽  
Hiv Risk ◽  
Full Text ◽  
Secondary School Students ◽  
Northern Province ◽  
School Students ◽  
Factors Affecting ◽  
Junior Secondary School ◽  
Junior Secondary

The purpose of this study was to identify factors affecting HIV risk reduction among junior secondary school pupils in South Africa. Opsomming Die doel van hierdie studie was om HIV risiko reduksie faktore onder junior sekondêre skool leerlinge in Suid-Afrika te identifiseer. *Please note: This is a reduced version of the abstract. Please refer to PDF for full text.

scholarly journals Editorial Comments/ Redaksionele Kommentaar

2005 ◽  
Vol 10 (2) ◽  
Author(s):  
V Roos
Keyword(s):  
South Africa ◽  
Health Care ◽  
Developing Country ◽  
Full Text

The challenges that health care face in a developing country such as South Africa are clearly illustrated in this edition of Health SA Gesondheid. Opsomming Die uitdagings waarmee gesondheidsorg in ‘n ontwikkelende land soos Suid-Afrika gekonfronteer word, word duidelik geillustreer in hierdie uitgawe van Health SA Gesondheid. *Please note: This is a reduced version of the abstract. Please refer to PDF for full text.

scholarly journals Die vroeë kommunikasieontwikkeling van ’n groep babas met pediatriese MIV/VIGS in sorgsentrums

2003 ◽  
Vol 8 (2) ◽  
Author(s):  
Isabel Bam ◽  
Alta Kritzinger ◽  
Brenda Louw
Keyword(s):  
South Africa ◽  
Human Immunodeficiency Virus ◽  
Primary Prevention ◽  
Full Text ◽  
Unique Combination ◽  
Developmental Needs ◽  
Early Management ◽  
Secondary Interventions ◽  
Immunodeficiency Virus ◽  
High Prevalence

The high prevalence and serious sequelae of the pediatric human immunodeficiency virus (HIV/AIDS) in South Africa pose great challenges for clinicians involved in early intervention to develop appropriate interdisciplinary programmes for primary prevention of transmission of the virus as well as secondary interventions directed at the early management of the unique combination of serious health problems, neuro-developmental needs and caregiving circumstances of the infants. Opsomming Die hoë prevalensie en ernstige gevolge van die pediatriese menslike immuniteitsgebrek-virus (MIV/VIGS) in Suid-Afrika stel groot uitdagings aan klinici betrokke by vroeë intervensie om toepaslike interdissiplinêre programme te ontwikkel vir primêre voorkoming van oordrag van die virus asook sekondêre intervensies gerig op die vroeë hantering van die babas se unieke kombinasie van ernstige Gesondheids-probleme, neuro-ontwikkelingsbehoeftes en versorgingsomstandighede. *Please note: This is a reduced version of the abstract. Please refer to PDF for full text.

Concepts and treatment modalities for hypertension by traditional and faith healers in the Northern Province, South Africa

2001 ◽  
Vol 6 (3) ◽  
pp. 59-67 ◽  
Author(s):  
K Peltzer ◽  
L B Khoza ◽  
M E Lekhuleni ◽  
S N Madu ◽  
V I Cherian ◽  
...  
Keyword(s):  
South Africa ◽  
Full Text ◽  
Treatment Modalities ◽  
Northern Province ◽  
Clinical Experiences ◽  
Research Findings

Clinical experiences and some research findings indicate that traditional and faith healers play a role in the management of hypertension in Africa.OpsommingKliniese ondervindings en sommige navorsingsbevindinge dui daarop dat tradisionele en geloofsgenesers ‘n rol speel in die hantering van hipertensie in Afrika. *Please note: This is a reduced version of the abstract. Please refer to PDF for full text.

scholarly journals The social construction of HIV/AIDS

2003 ◽  
Vol 8 (2) ◽  
Author(s):  
Natalie Goldstein ◽  
H G Pretorius ◽  
A D Stuart
Keyword(s):  
South Africa ◽  
Social Construction ◽  
Full Text ◽  
Aids Epidemic ◽  
The Social ◽  
The World ◽  
Hiv Aids

An in-depth look is taken at the specific discourses surrounding the debilitating HIV/AIDS epidemic sweeping South Africa and the world. Opsomming Hierdie artikel poog om ‘n indiepte ondersoek te loods na die spesifieke diskoerse rondom die MIV/VIGS epidemie in Suid-Afrika en die wêreld. *Please note: This is a reduced version of the abstract. Please refer to PDF for full text.

scholarly journals Public perception of community pharmacists in South Africa: a preliminary study

2006 ◽  
Vol 11 (3) ◽  
Author(s):  
Suzanne Bornman ◽  
Ilse Truter ◽  
Daniel JL Venter
Keyword(s):  
South Africa ◽  
Full Text ◽  
Public Perception ◽  
Community Pharmacists ◽  
Community Pharmacies ◽  
Self Medication ◽  
Over The Counter ◽  
Preliminary Study

This survey forms part of a study undertaken to identify and quantify the community pharmacist’s involvement in the use of non-prescription/over-the-counter (OTC) medicine/self-medication in community pharmacies throughout South Africa. Opsomming Hierdie opname vorm deel van ‘n studie wat onderneem word om die gemeenskapsapteker se betrokkenheid in die gebruik van nie-voorskrif/oor-die-toonbank medikasie/ selfmedikasie in gemeenskapsapteke in Suid Afrika te identifiseer en te kwantifiseer. *Please note: This is a reduced version of the abstract. Please refer to PDF for full text.

scholarly journals The contribution of the nurse manager to healthy labour relations: Part 2

1998 ◽  
Vol 3 (2) ◽  
pp. 11-17
Author(s):  
Marthie Bezuidenhout
Keyword(s):  
South Africa ◽  
Health Services ◽  
Full Text ◽  
Nurse Manager ◽  
Labour Relations

This study had its origins in the continuing evidence that health services in South Africa were increasingly being implicated in labour unrest. OpsommingDie studie het sy oorsprong in voortgesette bewyse dat die gesondheidsdienste in Suid-Afrika tot 'n al groter mate betrek word in arbeidsonrus. *Please note: This is a reduced version of the abstract. Please refer to PDF for full text.

scholarly journals The experience of nursing students in caring for aids patients

1997 ◽  
Vol 2 (3) ◽  
pp. 17-22
Author(s):  
Marieta Naude ◽  
Joyce Mokoena
Keyword(s):  
South Africa ◽  
Nursing Students ◽  
Full Text ◽  
Aids Patients

In South Africa the cumulative total of people suffering from AIDS between 1982 and 1991 was 969. OpsommingIn Suid-Afrika het 969 persone reeds tussen 1982 en 1991 aan VIGS gely (Epidemilogiese aantekeninge vol. 18, (11), November 1991). *Please note: This is a reduced version of the abstract. Please refer to PDF for full text.

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