scholarly journals Cardiovascular diseases and chronic obstructive pulmonary disease: etiopathogenetic relationship and clinical signifi cance (literature review)

2020 ◽  
Vol 35 (2) ◽  
pp. 26-34
Author(s):  
A. M. Chaulin ◽  
D. V. Duplyakov
Keyword(s):  
Oxidative Stress ◽  
Risk Factors ◽  
Chronic Obstructive Pulmonary Disease ◽  
Cardiovascular Diseases ◽  
Pulmonary Disease ◽  
Sedentary Lifestyle ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
The Relationship ◽  
And Oxidative Stress

Cardiovascular diseases (CVD) and chronic obstructive pulmonary disease (COPD) often coexist. Comorbidity of CVD and COPD is a serious modern medical and social problem. This article discusses the main risk factors that are common for COPD and CVD: smoking, infl ammation, a sedentary lifestyle, aging, and oxidative stress. Pathogenetic mechanisms underlying the relationship between COPD and CVD are also discussed.

scholarly journals COMBORIDITY OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND CARDIOVASCULAR DISEASES: GENERAL FACTORS, PATHOPHYSIOLOGICAL MECHANISMS AND CLINICAL SIGNIFICANCE

2020 ◽  
Author(s):  
Aleksey Mikhailovich Chaulin ◽  
Julia Vladimirovna Grigoryeva ◽  
Dmitriy Viktorovich Duplyakov
Keyword(s):  
Oxidative Stress ◽  
Chronic Obstructive Pulmonary Disease ◽  
Cardiovascular Diseases ◽  
Pulmonary Disease ◽  
Sedentary Lifestyle ◽  
Current Knowledge ◽  
Chronic Obstructive ◽  
Obstructive Pulmonary Disease ◽  
High Prevalence ◽  
Common Risk Factors

Currently, the comorbidity (combination) of chronic obstructive pulmonary disease (COPD) and cardiovascular diseases (CVD) is an relevant problem for health care. This is due to the high prevalence and continued growth of these pathologies. CVD and COPD have common risk factors and mechanisms underlying their development and progression: smoking, inflammation, sedentary lifestyle, aging, oxidative stress, air pollution, and hypoxia. In this review, we summarize current knowledge relating to the prevalence and frequency of cardiovascular diseases in people with COPD and the mechanisms that underlie their coexistence. The implications for clinical practice, in particular the main problems of diagnosis and treatment of COPD/CVD comorbidity, are also discussed.

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