scholarly journals Review of Pharmacological Properties, Phytochemistry and Medicinal Uses of Baccharoides adoensis

2020 ◽  
Vol 10 (5) ◽  
pp. 230-238
Author(s):  
Alfred Maroyi

Baccharoides adoensis is a shrub widely used as traditional medicine throughout its distributional range in tropical Africa. This study is aimed at providing a critical review of the pharmacological properties, phytochemistry, and medicinal uses of B. adoensis. Documented information on the pharmacological properties, phytochemistry, and medicinal uses of B. adoensis was collected from several online sources which included Scopus, Google Scholar, PubMed and Science Direct. Additional information on the pharmacological properties, phytochemistry, and medicinal uses of B. adoensis was gathered from pre-electronic sources such as book chapters, books, journal articles, and scientific publications sourced from the university library. The articles published between 1962 and 2020 were used in this study. This study showed that the roots, flowers, stems, and leaves of B adoensis are widely used as ethnoveterinary medicine and traditional medicines for backbone pain, reproductive problems, kidney diseases, fever and febrile complaints, wounds, ulcers, sexually transmitted infections, skin complaints, malaria, gastro-intestinal problems and respiratory problems. Phytochemical compounds identified from the species include alkaloids, carbohydrates, chondrillasterol, flavonoids, free sugars, glaucolides, glycosides, phenols, proanthocyanidin, saponins, steroids, tannins and terpenoids. Pharmacological research revealed that B. adoensis extracts and compounds isolated from the species have antimicrobial, antimycobacterial, anti-inflammatory, antioxidant, antiplasmodial, anti-pyretic, antitrypanosomal, antileishmanial, anti-ulcer and gastroprotective, immunomodulating, inhibition of Helicobacter pylori adhesion, larvicidal, cytotoxicity and toxicity activities. Baccharoides adoensis should be subjected to detailed phytochemical, pharmacological, and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological activities.

2020 ◽  
Vol 10 (5) ◽  
pp. 213-222
Author(s):  
Alfred Maroyi

Cissampelos mucronata A. Rich. is a perennial climber widely used as traditional medicine in tropical Africa. This study is aimed at providing a critical review of medicinal uses, phytochemical and pharmacological properties of C. mucronata. Documented information on medicinal uses, phytochemical and pharmacological properties of C. mucronata was collected from several online sources such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as book chapters, books, journal articles and scientific publications obtained from the University library. The articles published between 1962 and 2020 were used in this study. This study revealed that leaves, rhizome, roots and stems, and whole plant parts of C. mucronata are mainly used as traditional medicines for sexually transmitted infections, fever, swellings, headache, respiratory problems, snakebite, malaria, pregnancy problems and gastro-intestinal problems. Phytochemical compounds identified from the species include alkaloids, anthraquinones, flavonoids, glycerine, glycosides, phenolics, reducing sugars, resin, saponins, steroids, tannins and triterpenes. Pharmacological research revealed that C. mucronata extracts and alkaloids isolated from the species have antibacterial, anti-mycobacterial, antifungal, antiplasmodial, antitrypanosomal, anti-ulcer, anti-androgenic, anti-steroidogenic, enzyme tyrosine kinase p56 inhibitory, hypoglycemic, larvicidal, molluscicidal, sedative, tocolytic, uterine relaxant and cytotoxicity activities. There is need for extensive toxicological evaluations of crude extracts and compounds isolated from the species since C. mucronata contains potentially toxic compounds


2020 ◽  
Vol 10 (5) ◽  
pp. 190-195
Author(s):  
Alfred Maroyi

Cladostemon kirkii (Oliv.) Pax & Gilg is a shrub or a small tree widely used as traditional medicine in tropical Africa. This study is aimed at evaluating the chemical properties, biological activities and ethnomedicinal uses of C. kirkii. Results of the current study are based on data derived from several online databases such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as scientific publications, books, dissertations, book chapters and journal articles. The articles published between 1960 and 2019 were used in this study. This study revealed that the bark, leaf, root and stem infusion and/or decoction of C. kirkii are mainly used as traditional medicines for boils, colds, gastro-intestinal problems, hypertension, ophthalmia, rheumatism, sexual dysfunction, abdominal pains, sexually transmitted infections, sores and wounds. Phytochemical compounds identified from the species include mearnsitrin, myricitrin, kaempferol-5-rhamnoside, kaempferin, kaempferol 3-gluco-7-rhamnoside, quercetin 3,7-dirhamnoside, quercetin 3-gluco-7-rhamnoside, choline, 3-hydroxyprolinebetaine and tetramethylammonium. Cladostemon kirkii should be subjected to detailed phytochemical, pharmacological and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological properties.


2020 ◽  
Vol 10 (5) ◽  
pp. 287-294
Author(s):  
Alfred Maroyi

Centrapalus pauciflorus is a herbaceous plant that is used as a traditional medicine and a source of epoxidised oil. This study is aimed at providing a critical review of the pharmacological properties, phytochemistry and medicinal uses of C. pauciflorus. Documented information on the pharmacological properties, phytochemistry and medicinal uses of C. pauciflorus was collected from several online sources, which included Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as scientific publications, these, books, dissertations, book chapters and journal articles. This study showed that the leaves and epoxidised oil of C. pauciflorus are used as traditional medicines for external injury, wounds, diabetes, chest pains, eye infections, stomach problems and skin infections. Phytochemical compounds identified from the species include coumarins, essential oils, fatty acids, flavonol glycosides, phenolic acids, sterols, sesquiterpene lactones, triterpenoids, alkaloids, cardiac glycosides, carotenoids, flavonoids, polyuronoids, saponins, steroids, tannins and terpenoids. Pharmacological research revealed that C. pauciflorus extracts and compounds isolated from the species have analgesic, anti-dermatitis, antimicrobial, antiulcerogenic, hypoglycemic, insecticide, larvicidal and sedative activities. Centrapalus pauciflorus should be subjected to detailed phytochemical, pharmacological and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological activities.


Author(s):  
ALFRED MAROYI

This study is aimed at providing a critical review of the botany, biological activities and medicinal uses of P. prunelloides. Documented information on botany, biological activities, and medicinal uses of P. prunelloides was collected from several online sources which included BMC, Scopus, SciFinder, Google Scholar, Science Direct, Elsevier, PubMed, and Web of Science. Additional information on the botany, biological activities, and medicinal uses of P. prunelloides was gathered from book chapters, books, journal articles, theses, and scientific publications sourced from the University of Fort Hare Library. The study showed that the leaves and roots of P. prunelloides are used as herbal medicines for bodily pains, burns, cancer, diabetes, fever, gastrointestinal problems, heartburn, heart problems, respiratory problems, retained placenta, rheumatism, sexually transmitted infections, skin infections, snakebite, sores, wounds, toothache, and vomiting. Pharmacological research revealed that P. prunelloides extracts have antibacterial, antimycobacterial, antifungal, antiviral, antidiabetic, anti-inflammatory, analgesic, antioxidant, uterotonic and cytotoxicity activities. Future studies should focus on evaluating the phytochemical, pharmacological, and toxicological activities of P. prunelloides crude extracts as well as chemical compounds isolated from the species.


2020 ◽  
Vol 10 (5) ◽  
pp. 264-273
Author(s):  
Alfred Maroyi

Volkameria glabra (E. Mey.) Mabb. & Y.W. Yuan is a deciduous shrub or a small tree widely used as traditional medicine throughout its distributional range in tropical Africa. This study is aimed at providing a critical review of pharmacological properties, phytochemistry, and medicinal uses of V. glabra. Documented information on pharmacological properties, phytochemistry and medicinal uses of V. glabra was collected from several online sources such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as book chapters, books, journal articles and scientific publications obtained from the university library. This study revealed that the bark, leaf and root infusion and/or decoction of V. glabra are mainly used as immune booster, protective charm, anthelmintic and ethnoveterinary medicine, and traditional medicine for convulsions, fractured bones, fever, wounds, gastro-intestinal problems, snake bite and respiratory diseases. Phytochemical compounds identified from the species include aliphatic glycosides, anthraquinones, cardiac glycosides, flavonoids, iridoid, phenols, saponins, steroids, tannins and triterpenoids. The V. glabra and compounds isolated from the species exhibited acaricidal, anthelmintic, antibacterial, antifungal, antimycobacterial, anti-collagenase, antidiabetic, anti-elastase, anti-inflammatory, antileishmanial, antioxidant, antiplasmodial, antipyretic, cholinesterase enzyme inhibition, immune-stimulant and cytotoxicity activities. Volkameria glabra should be subjected to detailed phytochemical, pharmacological and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological activities.


2020 ◽  
Vol 11 (4) ◽  
pp. 5948-5955
Author(s):  
Alfred Maroyi

Cissampelos capensis L.f. is a perennial climber widely used as a traditional medicine in South Africa. This study was aimed at providing a critical review of medicinal uses, phytochemical and pharmacological properties of C. capensis. Documented information on the pharmacological properties, phytochemistry and medicinal uses of C. capensis was collected from several online sources such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as book chapters, books, journal articles and scientific publications obtained from the university library. This study revealed that leaf, rhizome and root infusions and decoctions of C. capensis are mainly used as a blood purifier, and traditional medicines for respiratory problems, ulcers, sores and wounds, skin and stomach cancers, snakebite, sexually transmitted infections, skin diseases, diabetes and gastrointestinal problems. Phytochemical compounds identified from the species include alkaloids, essential oils, flavonoids, phenolics, saponins and tannins. Pharmacological research revealed that C. capensis extracts and compounds isolated from the species have anthelmintic, antibacterial, antifungal, antidiabetic, antimalarial, hepatotoxicity, spermatozoa and cytotoxicity activities. Documentation of the medicinal uses, phytochemistry and pharmacological properties of C. capensis is vital as this information provides baseline data required for future research and development of health-promoting and pharmaceutical products. There is a need for extensive toxicological evaluations of crude extracts and compounds isolated from the species since C. capensis contains potentially toxic compounds.


2020 ◽  
Vol 10 (5) ◽  
pp. 247-256
Author(s):  
Alfred Maroyi

Maerua angolensis DC. is collected from the wild for its edible leaves and fruits, and is also used as a traditional medicine. This study is aimed at evaluating the ethnomedicinal uses, phytochemistry and pharmacological properties of M. angolensis. Results of the current study are based on data derived from several online databases such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as scientific publications, books, dissertations, book chapters and journal articles. The articles published between 1960 and 2020 were used in this study. This study revealed that the aerial parts, bark, leaves, roots and stem bark infusion and/or decoction of M. angolensis are mainly used as a protective charm and ethnoveterinary medicine, and a traditional medicine for pain, cancer, fever, malaria, sores, wounds and gastro-intestinal problems. Phytochemical compounds identified from the species include alkaloids, amino acids, anthraquinones, betaines, cardiac glycosides, cyanidin, esters, fatty acids, flavonoids, glucosinolates, phenols, saponins, sterols, steroids, tannins and triperpenoids. Ethnopharmacological research revealed that M. angolensis extracts have acaricidal, anthelmintic, antibacterial, antifungal, antidiarrhoeal, anticonvulsant, anti-diabetic, antidepressant, anti-inflammatory, antioxidant, antinociceptive, anxiolytic, anti-urolithiatic, antiprotozoal, molluscicidal and nematicidal activities. There is need for extensive toxicological evaluations of crude extracts and compounds isolated from the species since M. angolensis contains potentially toxic compounds


2020 ◽  
Vol 11 (4) ◽  
pp. 5855-5859
Author(s):  
Alfred Maroyi

Bersama lucens (Hochst.) Szyszyl is a shrub or small tree with its different parts used traditionally to treat various diseases. Bersama lucens has been recorded in Eswatini, Mozambique and South Africa. The main aim of this review is to provide an overview and critical analysis of the medicinal uses, phytochemistry and biological activities of B. lucens. The information presented in this study was gathered using various databases such as PubMed, Taylor and Francis imprints, Springer, NCBI, Google scholar and Science direct, and review of books, journal articles and other scientific publications kept in the University library. The bark and root infusion or decoction of B. lucens are mainly used as a blood purifier, lice repellent and protective charm, and traditional medicine for stomach problems, leprosy, stroke, sexually transmitted infections, headache, infertility, nervous disorders, impotence and menstrual pain. The biological activities exhibited by B. lucens extracts include antibacterial, antifungal and anti-inflammatory activities. Documentation of the medicinal uses, phytochemistry and pharmacological properties of B. lucens is vital as this information provides baseline data required for future research and development of health-promoting and pharmaceutical products. Future research should focus on detailed phytochemical, pharmacological and toxicological screening, in vivo studies and clinical trials involving the crude extracts and phytochemical compounds isolated from the species.


2020 ◽  
Vol 11 (4) ◽  
pp. 5089-5096
Author(s):  
Alfred Maroyi

Maerua edulis (Gilg & Gilg-Ben.) DeWolf  is collected from the wild for its edible fruits and also used as traditional medicine. This study is aimed at evaluating the ethnomedicinal uses, phytochemistry and pharmacological properties of M. edulis. Results of the current study are based on data derived from several online databases such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as scientific publications, books, dissertations, book chapters and journal articles. This study revealed that the bark, fruit, leaf, root and tuber infusion and decoction of M. edulis  are mainly used as a thirst quencher and ethnoveterinary medicine, and traditional medicine for eye infections, stomach ache, infertility in women, wounds, fungal infections, rheumatic swellings, cough and tuberculosis and sexually transmitted diseases. Phytochemical compounds identified from the species include agmatine, betaines, cardiac glycosides, fatty acids, flavonoids and quaternary ammonium compounds. Ethnopharmacological research revealed that M. edulis extracts and compounds isolated from the species have acaricidal, anthelmintic, antibacterial, antimycobacterial, antifungal, antiproliferative and insecticidal activities. Future research on M. edulis should focus on the possible biochemical mechanisms of both the crude extracts and identified phytochemical compounds including toxicological, in vivo and clinical studies to corroborate the traditional medicinal applications of the species.


2020 ◽  
Vol 10 (5) ◽  
pp. 182-189
Author(s):  
Alfred Maroyi

Maerua crassifolia Forssk. is an evergreen tree widely used as traditional medicine throughout its distributional range in the Sahel region, peninsular Arabia east to Pakistan, east and west Africa. This study is aimed at providing a critical review of medicinal uses, phytochemical and pharmacological properties of M. crassifolia. Documented information on medicinal uses, phytochemical and pharmacological properties of M. crassifolia was collected from several online sources such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as book chapters, books, journal articles and scientific publications obtained from the university library. The articles published between 1964 and 2020 were used in this study. This study revealed that the bark, fruit, leaf and twig infusion and/or decoction of M. crassifolia are mainly used as ethnoveterinary medicine, and traditional medicine for cephalalgia, headache, fever, malaria, wounds, skin infections, toothache and gastro-intestinal problems. Phytochemical compounds identified from the species include alkaloids, amino acids, betaines, cardiac glycosides, fatty acids, flavonoids, lignan glucosides, phenolics, quaternary ammonium compounds, saponins, steroids, tannins and terpenoids. The M. crassifolia extracts exhibited antibacterial, anti-diarrhoeal, analgesic, anti-inflammatory, antioxidant, antiplasmodial, antiprotozoal, antitrypanosomal, antipyretic and cytotoxicity activities. Maerua crassifolia should be subjected to detailed phytochemical, pharmacological and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological activities.


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