scholarly journals Maerua angolensis DC. (Capparaceae): A Review of its Medicinal Uses, Phytochemistry and Pharmacological Properties -

2020 ◽  
Vol 10 (5) ◽  
pp. 247-256
Author(s):  
Alfred Maroyi

Maerua angolensis DC. is collected from the wild for its edible leaves and fruits, and is also used as a traditional medicine. This study is aimed at evaluating the ethnomedicinal uses, phytochemistry and pharmacological properties of M. angolensis. Results of the current study are based on data derived from several online databases such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as scientific publications, books, dissertations, book chapters and journal articles. The articles published between 1960 and 2020 were used in this study. This study revealed that the aerial parts, bark, leaves, roots and stem bark infusion and/or decoction of M. angolensis are mainly used as a protective charm and ethnoveterinary medicine, and a traditional medicine for pain, cancer, fever, malaria, sores, wounds and gastro-intestinal problems. Phytochemical compounds identified from the species include alkaloids, amino acids, anthraquinones, betaines, cardiac glycosides, cyanidin, esters, fatty acids, flavonoids, glucosinolates, phenols, saponins, sterols, steroids, tannins and triperpenoids. Ethnopharmacological research revealed that M. angolensis extracts have acaricidal, anthelmintic, antibacterial, antifungal, antidiarrhoeal, anticonvulsant, anti-diabetic, antidepressant, anti-inflammatory, antioxidant, antinociceptive, anxiolytic, anti-urolithiatic, antiprotozoal, molluscicidal and nematicidal activities. There is need for extensive toxicological evaluations of crude extracts and compounds isolated from the species since M. angolensis contains potentially toxic compounds

2020 ◽  
Vol 10 (5) ◽  
pp. 264-273
Author(s):  
Alfred Maroyi

Volkameria glabra (E. Mey.) Mabb. & Y.W. Yuan is a deciduous shrub or a small tree widely used as traditional medicine throughout its distributional range in tropical Africa. This study is aimed at providing a critical review of pharmacological properties, phytochemistry, and medicinal uses of V. glabra. Documented information on pharmacological properties, phytochemistry and medicinal uses of V. glabra was collected from several online sources such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as book chapters, books, journal articles and scientific publications obtained from the university library. This study revealed that the bark, leaf and root infusion and/or decoction of V. glabra are mainly used as immune booster, protective charm, anthelmintic and ethnoveterinary medicine, and traditional medicine for convulsions, fractured bones, fever, wounds, gastro-intestinal problems, snake bite and respiratory diseases. Phytochemical compounds identified from the species include aliphatic glycosides, anthraquinones, cardiac glycosides, flavonoids, iridoid, phenols, saponins, steroids, tannins and triterpenoids. The V. glabra and compounds isolated from the species exhibited acaricidal, anthelmintic, antibacterial, antifungal, antimycobacterial, anti-collagenase, antidiabetic, anti-elastase, anti-inflammatory, antileishmanial, antioxidant, antiplasmodial, antipyretic, cholinesterase enzyme inhibition, immune-stimulant and cytotoxicity activities. Volkameria glabra should be subjected to detailed phytochemical, pharmacological and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological activities.


2020 ◽  
Vol 11 (4) ◽  
pp. 6196-6202
Author(s):  
Alfred Maroyi

Maerua triphylla A. Rich. is a shrub or small tree collected from the wild for its edible leaves and also used as traditional medicine. This study is aimed at evaluating the ethnomedicinal and ethnobotanical uses of M. triphylla. Results of the current study are based on data derived from several online databases such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as scientific publications, books, dissertations, book chapters and journal articles. This study revealed that the fruit, leaf, root, stem bark and twig infusion and/or decoction of M. triphylla  are mainly used as ethnoveterinary medicine, aphrodisiac and antidote for poisoning, and traditional medicine for rheumatism, boils, cancer, respiratory problems, snakebite, headache, migraine and gastro-intestinal problems. Phytochemical compounds identified from dried aerial parts and branches of M. triphylla include betaines and quaternary ammonium compounds such as 3-hydroxyprolinebetaine, glycine betaine, proline betaine and 3-hydroxy-1,1-dimethyl pyridinium.  Preliminary ethnopharmacological research revealed that M. triphylla leaf extracts have acaricidal and cytotoxicity activities. Documentation of the medicinal uses, phytochemistry and pharmacological properties of M. triphylla is important as this information provides baseline data required for future research focusing on ethnopharmacological properties of the species. Maerua triphylla should be subjected to detailed phytochemical, pharmacological and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological properties"


2020 ◽  
Vol 11 (4) ◽  
pp. 5089-5096
Author(s):  
Alfred Maroyi

Maerua edulis (Gilg & Gilg-Ben.) DeWolf  is collected from the wild for its edible fruits and also used as traditional medicine. This study is aimed at evaluating the ethnomedicinal uses, phytochemistry and pharmacological properties of M. edulis. Results of the current study are based on data derived from several online databases such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as scientific publications, books, dissertations, book chapters and journal articles. This study revealed that the bark, fruit, leaf, root and tuber infusion and decoction of M. edulis  are mainly used as a thirst quencher and ethnoveterinary medicine, and traditional medicine for eye infections, stomach ache, infertility in women, wounds, fungal infections, rheumatic swellings, cough and tuberculosis and sexually transmitted diseases. Phytochemical compounds identified from the species include agmatine, betaines, cardiac glycosides, fatty acids, flavonoids and quaternary ammonium compounds. Ethnopharmacological research revealed that M. edulis extracts and compounds isolated from the species have acaricidal, anthelmintic, antibacterial, antimycobacterial, antifungal, antiproliferative and insecticidal activities. Future research on M. edulis should focus on the possible biochemical mechanisms of both the crude extracts and identified phytochemical compounds including toxicological, in vivo and clinical studies to corroborate the traditional medicinal applications of the species.


2020 ◽  
Vol 10 (5) ◽  
pp. 182-189
Author(s):  
Alfred Maroyi

Maerua crassifolia Forssk. is an evergreen tree widely used as traditional medicine throughout its distributional range in the Sahel region, peninsular Arabia east to Pakistan, east and west Africa. This study is aimed at providing a critical review of medicinal uses, phytochemical and pharmacological properties of M. crassifolia. Documented information on medicinal uses, phytochemical and pharmacological properties of M. crassifolia was collected from several online sources such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as book chapters, books, journal articles and scientific publications obtained from the university library. The articles published between 1964 and 2020 were used in this study. This study revealed that the bark, fruit, leaf and twig infusion and/or decoction of M. crassifolia are mainly used as ethnoveterinary medicine, and traditional medicine for cephalalgia, headache, fever, malaria, wounds, skin infections, toothache and gastro-intestinal problems. Phytochemical compounds identified from the species include alkaloids, amino acids, betaines, cardiac glycosides, fatty acids, flavonoids, lignan glucosides, phenolics, quaternary ammonium compounds, saponins, steroids, tannins and terpenoids. The M. crassifolia extracts exhibited antibacterial, anti-diarrhoeal, analgesic, anti-inflammatory, antioxidant, antiplasmodial, antiprotozoal, antitrypanosomal, antipyretic and cytotoxicity activities. Maerua crassifolia should be subjected to detailed phytochemical, pharmacological and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological activities.


2020 ◽  
Vol 10 (5) ◽  
pp. 196-204
Author(s):  
Alfred Maroyi

Gymnanthemum coloratum is a shrub or a small tree widely used as traditional medicine throughout its distributional range in tropical Africa. The current study is aimed at reviewing the phytochemistry, pharmacological properties and medicinal uses of G. coloratum. Literature on pharmacological properties, phytochemistry and medicinal uses of G. coloratum was obtained from numerous internet sources such as Scopus, Elsevier, SciFinder, Google Scholar, Pubmed, ScienceDirect, BMC and Web of Science. Other sources of information included pre-electronic sources such as journal articles, theses, book chapters, books and other scientific publications obtained from the university library. The articles published between 1964 and 2020 were used in this study. The current study showed that G. coloratum is used as an anthelmintic, and traditional medicine for reproductive problems, schistosomiasis, liver diseases, sexually transmitted infections, diabetes, sores and wounds, respiratory problems, malaria, skin diseases, fever and gastro-intestinal problems. Ethnopharmacological research identified glaucolides, lactones, amino acids, essential oils, alkaloids, anthocyanins, cardenolids, coumarins, flavonoids, glycosides, leucoanthocyanins, phenols, quinones, reducing sugars, saponins, steroids, tannins, terpenoids and triterpenes from the aerial parts, leaves, roots and stems of G. coloratum. The aerial parts, leaves, roots and whole plant parts of G. coloratum and compounds isolated from the species exhibited anthelmintic, antimicrobial, anti-Blastocystis, anti-inflammatory, anti-sickling, insecticidal and larvicidal, antiplasmodial, antimalarial, antioxidant, antiproliferative, anti-Toxoplasma, hypoglycaemic and antidiabetic and cytotoxicity activities. Gymnanthemum coloratum should be subjected to detailed phytochemical, pharmacological and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological activities.


2020 ◽  
Vol 10 (5) ◽  
pp. 274-279
Author(s):  
Alfred Maroyi

Acanthosicyos horridus Welw. ex Hook. f. is a perennial shrub collected from the wild for its edible fruits and is also used as a traditional medicine. This study is aimed at evaluating the chemical properties and ethnomedicinal uses of A. horridus. Results of the current study are based on data derived from several online databases such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as scientific publications, books, dissertations, book chapters and journal articles. This study revealed that the fruit and root infusions and/or decoctions of A. horridus are used as traditional medicine for arteriosclerosis, chest pains, gastro-intestinal disorders, kidney problems, nausea and sexually transmitted infections. Phytochemical compounds identified from the species include cucurbitacins, fatty acids and sterols. Some of the compounds identified from the species have applications in food industry and health promoting products.


Author(s):  
Alfred Maroyi

Hilliardiellia aristata is a herbaceous plant species used as traditional medicine in southern Africa. The current investigation is aimed at reviewing the phytochemistry, pharmacological properties and medicinal uses of H. aristata. Results of the current study are based on literature search on pharmacological properties, phytochemistry and medicinal uses of H. aristata using information obtained from several internet sources such as Scopus, Elsevier, SciFinder, Google Scholar, Pubmed, ScienceDirect, BMC and Web of Science. Other sources of information included pre-electronic sources such as journal articles, theses, book chapters, books and other scientific publications obtained from the University library. The current study showed that H. aristata is used as a protective charm, traditional medicine for kidney problems, fever, headache, respiratory infections and malaria. Ethnopharmacological research identified glaucolides, lactones, alkaloids, phenols, tannins, glycosides, terpenoids, saponins, flavonoids and steroids from the aerial parts and leaves of H. aristata. The aerial parts, leaves, roots and whole plant parts of H. aristata exhibited anti-inflammatory, antibacterial, antifungal, antiplasmodial, antiprotozoal, larvicidal and cytotoxicity activities. Hilliardiella aristata should be subjected to detailed phytochemical, pharmacological and toxicological studies.


2020 ◽  
Vol 10 (5) ◽  
pp. 190-195
Author(s):  
Alfred Maroyi

Cladostemon kirkii (Oliv.) Pax & Gilg is a shrub or a small tree widely used as traditional medicine in tropical Africa. This study is aimed at evaluating the chemical properties, biological activities and ethnomedicinal uses of C. kirkii. Results of the current study are based on data derived from several online databases such as Scopus, Google Scholar, PubMed and Science Direct, and pre-electronic sources such as scientific publications, books, dissertations, book chapters and journal articles. The articles published between 1960 and 2019 were used in this study. This study revealed that the bark, leaf, root and stem infusion and/or decoction of C. kirkii are mainly used as traditional medicines for boils, colds, gastro-intestinal problems, hypertension, ophthalmia, rheumatism, sexual dysfunction, abdominal pains, sexually transmitted infections, sores and wounds. Phytochemical compounds identified from the species include mearnsitrin, myricitrin, kaempferol-5-rhamnoside, kaempferin, kaempferol 3-gluco-7-rhamnoside, quercetin 3,7-dirhamnoside, quercetin 3-gluco-7-rhamnoside, choline, 3-hydroxyprolinebetaine and tetramethylammonium. Cladostemon kirkii should be subjected to detailed phytochemical, pharmacological and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological properties.


2020 ◽  
Vol 10 (5) ◽  
pp. 230-238
Author(s):  
Alfred Maroyi

Baccharoides adoensis is a shrub widely used as traditional medicine throughout its distributional range in tropical Africa. This study is aimed at providing a critical review of the pharmacological properties, phytochemistry, and medicinal uses of B. adoensis. Documented information on the pharmacological properties, phytochemistry, and medicinal uses of B. adoensis was collected from several online sources which included Scopus, Google Scholar, PubMed and Science Direct. Additional information on the pharmacological properties, phytochemistry, and medicinal uses of B. adoensis was gathered from pre-electronic sources such as book chapters, books, journal articles, and scientific publications sourced from the university library. The articles published between 1962 and 2020 were used in this study. This study showed that the roots, flowers, stems, and leaves of B adoensis are widely used as ethnoveterinary medicine and traditional medicines for backbone pain, reproductive problems, kidney diseases, fever and febrile complaints, wounds, ulcers, sexually transmitted infections, skin complaints, malaria, gastro-intestinal problems and respiratory problems. Phytochemical compounds identified from the species include alkaloids, carbohydrates, chondrillasterol, flavonoids, free sugars, glaucolides, glycosides, phenols, proanthocyanidin, saponins, steroids, tannins and terpenoids. Pharmacological research revealed that B. adoensis extracts and compounds isolated from the species have antimicrobial, antimycobacterial, anti-inflammatory, antioxidant, antiplasmodial, anti-pyretic, antitrypanosomal, antileishmanial, anti-ulcer and gastroprotective, immunomodulating, inhibition of Helicobacter pylori adhesion, larvicidal, cytotoxicity and toxicity activities. Baccharoides adoensis should be subjected to detailed phytochemical, pharmacological, and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological activities.


2020 ◽  
Vol 11 (4) ◽  
pp. 5460-5466
Author(s):  
Alfred Maroyi

Schefflera umbellifera (Sond.) Baill. is an evergreen tree widely used as traditional medicine throughout its distributional range in southern Africa. Schefflera umbellifera is indigenous to Eswatini, Malawi, Mozambique, South Africa and Zimbabwe. This study was aimed at providing a critical review of medicinal uses, phytochemical and pharmacological properties of S. umbellifera. Documented information on medicinal uses, phytochemical and pharmacological properties of S. umbellifera was collected from several online sources such as Scopus, Google Scholar, PubMed, Francis and Taylor and Science Direct, and pre-electronic sources such as book chapters, books, journal articles and scientific publications obtained from the University library. This study revealed that the bark, leaf and root decoction or infusion of S. umbellifera are mainly used as diuretic, laxative, colic and protective charm, and traditional medicine for stomach ulcers, weaning infants, insanity, inflammation, rheumatism and malaria. Phytochemical compounds identified from the species include 3-hydroxy-20(29)-lupen-28-ol, 7-hydroxy-6-methoxycoumarin, betulin, ent-kaur-16-en-19-oic acid and oleanolic acid. Pharmacological research revealed that S. umbellifera extracts and compounds isolated from the species have antibacterial, anti-HIV, anti-inflammatory, antimalarial, antiprotozoal, larvicidal and cytotoxicity activities. Schefflera umbellifera should be subjected to detailed phytochemical, pharmacological and toxicological evaluations aimed at correlating its medicinal uses with its phytochemistry and pharmacological activities.


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